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compositionComposition:NORETHISTERONE-5MG
prescription
Prescription Medicine
info

Norfem 5mg Tablet is used to treat heavy, painful, or irregular periods, premenstrual syndrome (PMS), and endometriosis. Additionally, it may be used in the treatment of breast cancer. It contains Norethisterone, which works by restoring the hormone levels in the body. In some cases, this medicine may cause side effects such as unusual vaginal bleeding or spotting, dizziness, dry mouth, constipation, nausea, and diarrhoea. Let the doctor know if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

NORETHISTERONE-5MG

Manufacturer/Marketer :

Femgrace Formulations

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Norfem 5mg Tablet

Norfem 5mg Tablet is an oral prescription medication used to manage heavy periods, painful menstruation, and irregular cycles. It is also commonly prescribed to treat endometriosis and to temporarily delay the onset of a period. By regulating hormone levels in your body, this medicine helps restore a manageable and predictable menstrual cycle.

For best results, you must take Norfem 5mg Tablet consistently at the same time each day as directed by your healthcare provider. You can take this tablet with or without food, though taking it with a glass of water is recommended. Incorporating a balanced diet and regular, moderate exercise can further support your body's hormonal balance and improve your treatment results.

While taking Norfem 5mg Tablet, you may experience mild, temporary side effects such as nausea, headaches, or breast tenderness. Most of these symptoms subside as your body adjusts, but you should contact your doctor immediately if you experience severe symptoms like sudden chest pain or shortness of breath.

Talk to your doctor before starting this medicine if you have a history of high blood pressure, diabetes, or migraines. Do not take this if you are pregnant, have active liver damage, a history of blood clots, or unexplained vaginal bleeding.

This medication can interact with certain epilepsy treatments, tuberculosis therapies, and herbal supplements, which may reduce how well it works. Avoid smoking while taking Norfem 5mg Tablet, as smoking significantly increases your risk of developing serious blood clots. If you are breastfeeding, elderly, or planning a pregnancy, always consult your doctor or pharmacist before starting treatment.

Uses of Norfem 5mg Tablet

Norfem 5mg Tablet is used to manage heavy periods, painful menstruation, and irregular cycles. The detailed uses of Norfem 5mg Tablet are as follows:

  • Heavy menstrual bleeding: Norfem 5mg Tablet helps control and significantly lighten abnormally heavy or prolonged blood flow during your cycle.
  • Painful periods: It reduces severe cramping, pelvic discomfort, and abdominal pain associated with menstruation.
  • Endometriosis: It works by limiting the abnormal growth of the womb lining outside the uterus, relieving chronic pelvic pain and inflammation.
  • Delaying periods: It temporarily postpones your menstrual cycle for travel, medical procedures, or personal convenience.

Key Benefits

Norfem 5mg Tablet helps manage heavy and painful menstrual periods by reducing excessive bleeding and relieving menstrual discomfort. With regular use, it supports better energy levels, improves daily comfort, and enhances overall quality of life.

  • Controls Heavy Menstrual Bleeding: By reducing excessive blood loss during menstruation, this medicine helps lower the risk of iron deficiency, reducing fatigue and physical weakness while supporting better energy levels.
  • Relieves Menstrual and Pelvic Pain: This medicine helps ease painful menstrual cramps, pelvic discomfort, and lower back pain associated with conditions such as endometriosis, improving comfort throughout your menstrual cycle.
  • Supports an Active Lifestyle: By reducing heavy bleeding and menstrual pain, this medicine helps improve physical mobility, allowing you to carry out your daily activities with greater confidence and comfort.

Directions for Use

  • Norfem 5mg Tablet can be taken with or without food, or as advised by the doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Norfem 5mg Tablet as a whole with a glass of water.
  • Do not chew, crush or break it.

How Norfem 5mg Tablet Works

Norfem 5mg Tablet contains a synthetic version of progesterone, norethisterone, a natural female sex hormone that regulates the monthly menstrual cycle. Under normal conditions, a drop in progesterone levels triggers the shedding of the womb lining, resulting in a period. This medicine works by maintaining steady hormone levels in your body. By mimicking natural progesterone, it prevents the womb lining from growing too quickly or shedding prematurely. This stabilisation helps stop irregular bleeding, lightens heavy cycles, and prevents menstruation entirely for as long as you continue taking the medication under medical supervision.
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Alcohol

Consult your doctor

The interaction of Norfem 5mg Tablet with alcohol is unknown. Please consult a doctor before consuming alcohol while using Norfem 5mg Tablet.

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Pregnancy

Unsafe

Norfem 5mg Tablet is a category X pregnancy drug and is not recommended for use during pregnancy as it may harm the unborn baby. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Consult your doctor

Norfem 5mg Tablet is given to breastfeeding women only if the doctor thinks benefits are greater than risks. Please consult a doctor if you are breastfeeding.

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Driving

Safe if prescribed

Norfem 5mg Tablet usually does not affect your ability to drive or operate machinery.

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Liver

Unsafe

Norfem 5mg Tablet is not recommended if you have liver disease. However, if you have any concerns regarding this, please consult a doctor.

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Kidney

Caution

Take Norfem 5mg Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Norfem 5mg Tablet is not recommended for use in children under 18 years.

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Heart

Caution

Norfem 5mg Tablet should be used with caution in patients with heart problems. Inform your doctor about any heart-related conditions before taking Norfem 5mg Tablet.

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Geriatrics

Unsafe

Norfem 5mg Tablet is generally not recommended for elderly patients due to an increased risk of side effects and reduced effectiveness.

What if I have taken an overdose of Norfem 5mg Tablet

In case of an accidental overdose, seek immediate medical attention. Symptoms of an overdose may include severe nausea, vomiting, dizziness, or unexpected vaginal bleeding.

Diet & Lifestyle Advise

  • Increase iron-rich foods: If you experience heavy bleeding, eat more spinach, lean red meats, beans, and fortified cereals to help prevent anaemia and fatigue.
  • Stay hydrated: Drink plenty of water throughout the day to help reduce bloating and support overall metabolic function.
  • Engage in gentle exercise: Activities like walking, swimming, or yoga can naturally relieve menstrual cramps, improve pelvic blood flow, and boost your mood.
  • Track your symptoms: Keep a detailed diary of your period dates, bleeding intensity, and any side effects to share with your doctor during follow-up visits.
  • Avoid smoking: Smoking while taking hormone treatments significantly increases the risk of serious cardiovascular complications, including blood clots.
health query

Have a query?

How Soon It Starts Working

  • The time required for Norfem 5mg Tablet to start to work: The time required for Norfem 5mg Tablet to show its action is unknown.
  • The time for which the effects of Norfem 5mg Tablet last: The duration of action for Norfem 5mg Tablet is clinically unknown.

What if you forget to take Norfem 5mg Tablet

If you miss a dose, take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for a forgotten tablet, as this may increase your risk of side effects. If you are using this medicine to delay your period, a missed dose may cause breakthrough bleeding or spotting.

Storage

•Store Norfem 5mg Tablet oral tablets at room temperature, ideally below 25°C or 30°C. •Keep the tablets in their original packaging to protect them from direct light and moisture.

Drug Warnings

  • Always confirm with your doctor that Norfem 5mg Tablet is safe for you if you have a history of blood clots, heart disease, or liver problems.
  • Do not rely on Norfem 5mg Tablet as a contraceptive unless your doctor has specifically prescribed it for that purpose; use a barrier method like condoms if you need to prevent pregnancy.
  • Stop taking this medicine immediately and contact your doctor if you experience a sudden migraine, visual disturbances, or severe leg pain.
  • Inform your surgeon or dentist that you are taking this medication well in advance of any planned surgeries, as you may need to stop taking it temporarily to lower your risk of blood clots.
  • Check your blood pressure regularly while taking this medication, especially if you have a history of hypertension.

Drug-Drug Interactions

verifiedApollotooltip
  • Epilepsy medications: Taking this medicine with drugs like carbamazepine, phenytoin, or phenobarbital may reduce its effectiveness.
  • Tuberculosis treatments: Rifampicin and rifabutin can speed up how your liver processes Norfem 5mg Tablet, making it less effective.
  • Herbal remedies: St. John’s Wort can lower the levels of this medicine in your body, reducing its ability to control your symptoms.
NorethisteroneTelaprevir
Severe

Drug-Drug Interactions

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NorethisteroneTelaprevir
Severe
How does the drug interact with Norfem 5mg Tablet:
Using Telaprevir and Norfem 5mg Tablet together can increase risk of unintended pregnancy and decrease the effectiveness of norethindrone.

How to manage the interaction:
Combining Telaprevir with Norfem 5mg Tablet can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms like increased hot flashes, vaginal dryness, or menstrual abnormalities, contact the doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Norfem 5mg Tablet:
Co-administration of Norfem 5mg Tablet with Bosentan can reduce the blood levels and effects of norethindrone.

How to manage the interaction:
Taking Norfem 5mg Tablet with Bosentan together can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to a doctor.
How does the drug interact with Norfem 5mg Tablet:
Coadministration of Acitretin with Norfem 5mg Tablet may interfere with the contraceptive effect of Norfem 5mg Tablet.

How to manage the interaction:
Acitretin and Norfem 5mg Tablet should be used together only if prescribed by your doctor. Use of at least two methods of effective contraception is mandatory during acitretin therapy and for at least 3 years after stopping therapy.
NorethisteroneBexarotene
Severe
How does the drug interact with Norfem 5mg Tablet:
Coadministration of Bexarotene and Norfem 5mg Tablet together can decrease the effectiveness of norethindrone and increase the risk of unintended pregnancy.

How to manage the interaction:
Combining Bexarotene with Norfem 5mg Tablet can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms like increased hot flashes, vaginal dryness, or menstrual abnormalities, contact the doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Norfem 5mg Tablet:
Coadministration of Phenytoin and Norfem 5mg Tablet may decrease the blood levels of Norfem 5mg Tablet, which may make Norfem 5mg Tablet less effective.

How to manage the interaction:
Although taking Phenytoin and Norfem 5mg Tablet together can result in an interaction, it can be taken if your doctor has prescribed it. If you experience any symptoms, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Norfem 5mg Tablet:
Using Felbamate and Norfem 5mg Tablet together can reduce the blood levels and effects of norethindrone.

How to manage the interaction:
There may be a possibility of interaction between Norfem 5mg Tablet and Felbamate, but it can be taken if prescribed by a doctor. If you notice any unusual symptoms like changes in your menstrual cycle, excessive bleeding, make sure to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Norfem 5mg Tablet:
Taking Norfem 5mg Tablet with rifampicin can decrease the blood levels of Norfem 5mg Tablet, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between Norfem 5mg Tablet and rifampicin, they can be taken together if prescribed by a doctor. However, if you experience abnormal bleeding, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
NorethisteroneRifapentine
Severe
How does the drug interact with Norfem 5mg Tablet:
Combining Rifapentine and norethindrone reduces the blood levels and effects of norethindrone and increases the risk of bleeding and unintended pregnancy.

How to manage the interaction:
Although there is a possible interaction between Norfem 5mg Tablet and Rifapentine, you can take these medicines together if prescribed by your doctor. If you're having any of these symptoms like unexpected bleeding, abnormal bleeding, it's important to reach out to a doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Norfem 5mg Tablet:
Eslicarbazepine may reduce the effects of Norfem 5mg Tablet and its blood levels.

How to manage the interaction:
Although taking Eslicarbazepine and Norfem 5mg Tablet results in an interaction, they can be taken together if prescribed by your doctor. Do not stop using any medications without consulting a doctor.
NorethisteroneFosphenytoin
Severe
How does the drug interact with Norfem 5mg Tablet:
Coadministration of Norfem 5mg Tablet with Fosphenytoin can reduces the blood levels and effects of Norfem 5mg Tablet .

How to manage the interaction:
Taking Norfem 5mg Tablet with Fosphenytoin together can result in an interaction, but it can be taken if your doctor has advised it. If you experience symptoms of abnormal bleeding while using birth control, it's important to contact a doctor right away. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip

No clinically significant food interactions are known with Norfem 5mg Tablet when used as directed. 

NORETHISTERONE-5MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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NORETHISTERONE-5MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Consuming Grapefruit juice may increase the blood levels of Norfem 5mg Tablet. Avoid or limit the consumption of grapefruit and grapefruit juice while taking the Norfem 5mg Tablet dose. Avoid or limit the consumption of grapefruit and grapefruit juice while taking the Norfem 5mg Tablet dose.

All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[PROGESTIN]

FAQs

Norfem 5mg Tablet is used to treat heavy, painful, or irregular periods, premenstrual syndrome (PMS), and endometriosis. Additionally, Norfem 5mg Tablet may be used in the treatment of breast cancer.
Norfem 5mg Tablet contains Norethisterone, a synthetic hormone that mimics the activity of the natural hormone progesterone. Thereby, it restores hormone levels in the body and regulates the growth and shedding of the womb lining. Thus, it helps to treat menstrual disorders.
Norfem 5mg Tablet may be used to delay periods. Norfem 5mg Tablet keeps progesterone levels high and prevents shedding of the womb lining. However, please consult a doctor before using Norfem 5mg Tablet.
Norfem 5mg Tablet may increase the risk of a blood clot in the veins of the leg, especially if you are overweight, smoke, or have a history of a blood clot in the lungs or veins, repeated miscarriage or have major surgery, serious injury, or systemic lupus erythematosus (autoimmune disease). Therefore, please inform your doctor if you have any of these conditions before taking Norfem 5mg Tablet.
You are not recommended to take Norfem 5mg Tablet with rifampicin as it may decrease the levels of Norfem 5mg Tablet in blood and reduce its effectiveness. However, please consult a doctor before taking Norfem 5mg Tablet with other medicines.
Periods usually resume within 3 days of discontinuing Norfem 5mg Tablet. However, please consult a doctor if you have any concerns regarding this.
Norfem 5mg Tablet may cause changes in blood sugar levels. Therefore, it is advised to regularly monitor blood sugar levels while taking Norfem 5mg Tablet and inform your doctor if you have diabetes before taking Norfem 5mg Tablet.
No, Norfem 5mg Tablet is not a contraceptive on its own.
No, Norfem 5mg Tablet is unlikely to cause weight loss.
The recommended dosage can vary greatly depending on the reason for taking the medication. It's crucial to follow your doctor's instructions precisely. Taking an incorrect dosage can lead to ineffective treatment or adverse side effects.
No, Norfem 5mg Tablet does not cause miscarriages. However, it is not safe to take Norfem 5mg Tablet during pregnancy.
Norfem 5mg Tablet can generally be taken either before or after a meal. There is no strict requirement regarding the timing of food intake.
Norfem 5mg Tablet contains Norethisterone, a second-generation progestin.
The duration of Norfem 5mg Tablet use can vary depending on the specific medical condition being treated.
Yes, Norfem 5mg Tablet treats irregular menstrual cycles.
Even after taking Norfem 5mg Tablet and having unprotected sex, one can get pregnant. However, Norfem 5mg Tablet is a category X pregnancy drug. It is not recommended for use during pregnancy as it may harm the unborn baby. Please consult a doctor if you are pregnant or planning for pregnancy.
Common side effects of Norfem 5mg Tablet may cause unusual vaginal bleeding or spotting, dizziness, dry mouth, constipation, nausea, diarrhoea, headache, breast pain, and tenderness. Most of these side effects of Norfem 5mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Yes, Norfem 5mg Tablet can lead to weight gain in some persons. However, it's crucial to remember that this isn't a common adverse effect. The potential risk of weight gain varies based on the individual and the dosage. Talk to your doctor or pharmacist if you are concerned about weight gain or have any other questions regarding norethisterone acetate. They can provide personalized information based on your circumstances.
Limited research is available. Seek medical attention from your doctor if you have any questions. Remember that self-medication can be risky. Always consult with a healthcare professional for proper diagnosis and treatment.
Yes, bleeding may occasionally occur while taking Norfem 5mg Tablet. If you're experiencing bleeding while on Norfem 5mg Tablet and you're concerned, it's important to consult with your healthcare provider. They can determine if the bleeding is normal or if there's another underlying issue.
Norfem 5mg Tablet usually stops irregular bleeding within a few days, but this varies from person to person. If bleeding persists or worsens, consult your doctor.
The duration of Norfem 5mg Tablet use depends on your specific medical condition and the reason for taking it.
The exact dosage and schedule for Norfem 5mg Tablet will vary based on your individual health needs. It is important to follow your doctor's instructions to ensure effective treatment and minimize side effects.
If you forget a dose of Norfem 5mg Tablet, take it as soon as possible. If it's been more than 12 hours, skip the missed dose and continue with your regular schedule or as directed by the physician.
Yes, Norfem 5mg Tablet can interact with other medications. It's important to avoid taking Norfem 5mg Tablet with any medications without consulting your doctor first. They can assess the potential risks and benefits and recommend alternative treatments if necessary.
Store in a cool and dry place away from sunlight. Keep Norfem 5mg Tablet out of reach and out of sight to children.
Norfem 5mg Tablet can be used to treat long-term disorders like endometriosis. But you should talk to your doctor about the long-term advantages and risks.
There is no direct drug interaction between alcohol and Norfem 5mg Tablet. However, heavy alcohol consumption can stress your liver and worsen side effects like headache or nausea. It is best to limit alcohol intake while taking this medicine. Talk to your doctor for further guidance.
This medicine is generally not recommended for breastfeeding mothers, as small amounts of the hormone can pass into breast milk and may affect milk production. Always consult your doctor or pharmacist to discuss safer alternatives.
Yes, it is generally safe to take common over-the-counter painkillers like ibuprofen or paracetamol alongside Norfem 5mg Tablet to manage menstrual cramps or headaches. However, it is always a good practice to talk to your doctor or pharmacist before combining any medications.

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Country of origin

India

Manufacturer/Marketer address

203, 2nd Floor, Aditraj Arcade, Near Hetvi Tower,100 Feet Ring Road, Satellite, Ahmedabad, Gujarat 380015.
Other Info - NO92358
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