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compositionComposition:NORETHISTERONE-5MG
prescription
Prescription Medicine
info
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Normendo 5mg Tablet is used to treat heavy, painful, or irregular periods, premenstrual syndrome (PMS), and endometriosis. Additionally, it may be used in the treatment of breast cancer. It contains Norethisterone, which works by restoring the hormone levels in the body. In some cases, this medicine may cause side effects such as unusual vaginal bleeding or spotting, dizziness, dry mouth, constipation, nausea, and diarrhoea. Let the doctor know if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

NORETHISTERONE-5MG

Manufacturer/Marketer :

Curewin Hylico Pharma Pvt Ltd

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Normendo 5mg Tablet

Normendo 5mg Tablet is an oral prescription medication used to manage heavy periods, painful menstruation, and irregular cycles. It is also commonly prescribed to treat endometriosis and to temporarily delay the onset of a period. By regulating hormone levels in your body, this medicine helps restore a manageable and predictable menstrual cycle.

For best results, you must take Normendo 5mg Tablet consistently at the same time each day as directed by your healthcare provider. You can take this tablet with or without food, though taking it with a glass of water is recommended. Incorporating a balanced diet and regular, moderate exercise can further support your body's hormonal balance and improve your treatment results.

While taking Normendo 5mg Tablet, you may experience mild, temporary side effects such as nausea, headaches, or breast tenderness. Most of these symptoms subside as your body adjusts, but you should contact your doctor immediately if you experience severe symptoms like sudden chest pain or shortness of breath.

Talk to your doctor before starting this medicine if you have a history of high blood pressure, diabetes, or migraines. Do not take this if you are pregnant, have active liver damage, a history of blood clots, or unexplained vaginal bleeding.

This medication can interact with certain epilepsy treatments, tuberculosis therapies, and herbal supplements, which may reduce how well it works. Avoid smoking while taking Normendo 5mg Tablet, as smoking significantly increases your risk of developing serious blood clots. If you are breastfeeding, elderly, or planning a pregnancy, always consult your doctor or pharmacist before starting treatment.

Uses of Normendo 5mg Tablet

Normendo 5mg Tablet is used to manage heavy periods, painful menstruation, and irregular cycles. The detailed uses of Normendo 5mg Tablet are as follows:

  • Heavy menstrual bleeding: Normendo 5mg Tablet helps control and significantly lighten abnormally heavy or prolonged blood flow during your cycle.
  • Painful periods: It reduces severe cramping, pelvic discomfort, and abdominal pain associated with menstruation.
  • Endometriosis: It works by limiting the abnormal growth of the womb lining outside the uterus, relieving chronic pelvic pain and inflammation.
  • Delaying periods: It temporarily postpones your menstrual cycle for travel, medical procedures, or personal convenience.

Key Benefits

Normendo 5mg Tablet helps manage heavy and painful menstrual periods by reducing excessive bleeding and relieving menstrual discomfort. With regular use, it supports better energy levels, improves daily comfort, and enhances overall quality of life.

  • Controls Heavy Menstrual Bleeding: By reducing excessive blood loss during menstruation, this medicine helps lower the risk of iron deficiency, reducing fatigue and physical weakness while supporting better energy levels.
  • Relieves Menstrual and Pelvic Pain: This medicine helps ease painful menstrual cramps, pelvic discomfort, and lower back pain associated with conditions such as endometriosis, improving comfort throughout your menstrual cycle.
  • Supports an Active Lifestyle: By reducing heavy bleeding and menstrual pain, this medicine helps improve physical mobility, allowing you to carry out your daily activities with greater confidence and comfort.

Directions for Use

  • Normendo 5mg Tablet can be taken with or without food, or as advised by the doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Normendo 5mg Tablet as a whole with a glass of water.
  • Do not chew, crush or break it.

How Normendo 5mg Tablet Works

Normendo 5mg Tablet contains a synthetic version of progesterone, norethisterone, a natural female sex hormone that regulates the monthly menstrual cycle. Under normal conditions, a drop in progesterone levels triggers the shedding of the womb lining, resulting in a period. This medicine works by maintaining steady hormone levels in your body. By mimicking natural progesterone, it prevents the womb lining from growing too quickly or shedding prematurely. This stabilisation helps stop irregular bleeding, lightens heavy cycles, and prevents menstruation entirely for as long as you continue taking the medication under medical supervision.
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Alcohol

Consult your doctor

The interaction of Normendo 5mg Tablet with alcohol is unknown. Please consult a doctor before consuming alcohol while using Normendo 5mg Tablet.

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Pregnancy

Unsafe

Normendo 5mg Tablet is a category X pregnancy drug and is not recommended for use during pregnancy as it may harm the unborn baby. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Consult your doctor

Normendo 5mg Tablet is given to breastfeeding women only if the doctor thinks benefits are greater than risks. Please consult a doctor if you are breastfeeding.

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Driving

Safe if prescribed

Normendo 5mg Tablet usually does not affect your ability to drive or operate machinery.

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Liver

Unsafe

Normendo 5mg Tablet is not recommended if you have liver disease. However, if you have any concerns regarding this, please consult a doctor.

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Kidney

Caution

Take Normendo 5mg Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Normendo 5mg Tablet is not recommended for use in children under 18 years.

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Heart

Caution

Normendo 5mg Tablet should be used with caution in patients with heart problems. Inform your doctor about any heart-related conditions before taking Normendo 5mg Tablet.

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Geriatrics

Unsafe

Normendo 5mg Tablet is generally not recommended for elderly patients due to an increased risk of side effects and reduced effectiveness.

What if I have taken an overdose of Normendo 5mg Tablet

In case of an accidental overdose, seek immediate medical attention. Symptoms of an overdose may include severe nausea, vomiting, dizziness, or unexpected vaginal bleeding.

Diet & Lifestyle Advise

  • Increase iron-rich foods: If you experience heavy bleeding, eat more spinach, lean red meats, beans, and fortified cereals to help prevent anaemia and fatigue.
  • Stay hydrated: Drink plenty of water throughout the day to help reduce bloating and support overall metabolic function.
  • Engage in gentle exercise: Activities like walking, swimming, or yoga can naturally relieve menstrual cramps, improve pelvic blood flow, and boost your mood.
  • Track your symptoms: Keep a detailed diary of your period dates, bleeding intensity, and any side effects to share with your doctor during follow-up visits.
  • Avoid smoking: Smoking while taking hormone treatments significantly increases the risk of serious cardiovascular complications, including blood clots.
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How Soon It Starts Working

  • The time required for Normendo 5mg Tablet to start to work: The time required for Normendo 5mg Tablet to show its action is unknown.
  • The time for which the effects of Normendo 5mg Tablet last: The duration of action for Normendo 5mg Tablet is clinically unknown.

What if you forget to take Normendo 5mg Tablet

If you miss a dose, take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for a forgotten tablet, as this may increase your risk of side effects. If you are using this medicine to delay your period, a missed dose may cause breakthrough bleeding or spotting.

Storage

•Store Normendo 5mg Tablet oral tablets at room temperature, ideally below 25°C or 30°C. •Keep the tablets in their original packaging to protect them from direct light and moisture.

Drug Warnings

  • Always confirm with your doctor that Normendo 5mg Tablet is safe for you if you have a history of blood clots, heart disease, or liver problems.
  • Do not rely on Normendo 5mg Tablet as a contraceptive unless your doctor has specifically prescribed it for that purpose; use a barrier method like condoms if you need to prevent pregnancy.
  • Stop taking this medicine immediately and contact your doctor if you experience a sudden migraine, visual disturbances, or severe leg pain.
  • Inform your surgeon or dentist that you are taking this medication well in advance of any planned surgeries, as you may need to stop taking it temporarily to lower your risk of blood clots.
  • Check your blood pressure regularly while taking this medication, especially if you have a history of hypertension.

Drug-Drug Interactions

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  • Epilepsy medications: Taking this medicine with drugs like carbamazepine, phenytoin, or phenobarbital may reduce its effectiveness.
  • Tuberculosis treatments: Rifampicin and rifabutin can speed up how your liver processes Normendo 5mg Tablet, making it less effective.
  • Herbal remedies: St. John’s Wort can lower the levels of this medicine in your body, reducing its ability to control your symptoms.
NorethisteroneAcitretin
Severe
NorethisteronePhenobarbital
Severe

Drug-Drug Interactions

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NorethisteroneAcitretin
Severe
How does the drug interact with Normendo 5mg Tablet:
Coadministration of Acitretin with Normendo 5mg Tablet may interfere with the contraceptive effect of Normendo 5mg Tablet.

How to manage the interaction:
Acitretin and Normendo 5mg Tablet should be used together only if prescribed by your doctor. Use of at least two methods of effective contraception is mandatory during acitretin therapy and for at least 3 years after stopping therapy.
NorethisteronePhenobarbital
Severe
How does the drug interact with Normendo 5mg Tablet:
The combined use of Normendo 5mg Tablet and phenobarbital can reduce the blood levels and effects of Normendo 5mg Tablet.

How to manage the interaction:
Although taking phenobarbital and Normendo 5mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. If you experience any symptoms like abnormal bleeding, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
NorethisteroneEtretinate
Severe
How does the drug interact with Normendo 5mg Tablet:
Using Etretinate and Normendo 5mg Tablet together can cause severe, birth defects. Never use etretinate if you are pregnant. Both a primary and a secondary form of birth control must be used together and for at least 3 years after stopping therapy.

How to manage the interaction:
Although taking Normendo 5mg Tablet and Etretinate together can cause an interaction, it can be taken if your doctor has suggested it. If you notice any of these signs, make sure to contact your doctor right away. These symptoms may be related to your birth control. Do not stop using any medications without a doctor's advice.
NorethisteroneGriseofulvin
Severe
How does the drug interact with Normendo 5mg Tablet:
Taking griseofulvin with Normendo 5mg Tablet may reduce blood levels and the effects of Normendo 5mg Tablet.

How to manage the interaction:
Although there is a possible interaction between Griseofulvin and Normendo 5mg Tablet, you can take these medicines together if prescribed by a doctor. However, if you experience any of these symptoms like unexpected bleeding or abnormal bleeding, it's important to contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
NorethisteroneTranexamic acid
Severe
How does the drug interact with Normendo 5mg Tablet:
Using tranexamic acid together with norethindrone may increase the risk of blood clots.

How to manage the interaction:
Taking Normendo 5mg Tablet with tranexamic acid can lead to an interaction, however, it can be taken only if a doctor has advised it. If you experience symptoms such as chest pain, shortness of breath, coughing up blood, blood in the urine, sudden loss of vision, and pain, redness, or swelling in your arm or leg, contact a doctor immediately .Do not discontinue any medications without consulting a doctor.
NorethisteroneBosentan
Severe
How does the drug interact with Normendo 5mg Tablet:
Co-administration of Normendo 5mg Tablet with Bosentan can reduce the blood levels and effects of norethindrone.

How to manage the interaction:
Taking Normendo 5mg Tablet with Bosentan together can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to a doctor.
NorethisteroneRifapentine
Severe
How does the drug interact with Normendo 5mg Tablet:
Combining Rifapentine and norethindrone reduces the blood levels and effects of norethindrone and increases the risk of bleeding and unintended pregnancy.

How to manage the interaction:
Although there is a possible interaction between Normendo 5mg Tablet and Rifapentine, you can take these medicines together if prescribed by your doctor. If you're having any of these symptoms like unexpected bleeding, abnormal bleeding, it's important to reach out to a doctor right away. Do not discontinue any medications without consulting a doctor.
NorethisteroneTopiramate
Severe
How does the drug interact with Normendo 5mg Tablet:
Coadministration of Normendo 5mg Tablet with Topiramate can reduce the blood levels and effects of norethindrone in the body. This increases the risk of severe bleeding and unintended pregnancy.

How to manage the interaction:
Taking Normendo 5mg Tablet and topiramate together can result in an interaction; it can be taken if your doctor has advised it. However, if you notice any symptoms of abnormal bleeding, hot flashes or vaginal dryness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
NorethisteronePhenytoin
Severe
How does the drug interact with Normendo 5mg Tablet:
Coadministration of Phenytoin and Normendo 5mg Tablet may decrease the blood levels of Normendo 5mg Tablet, which may make Normendo 5mg Tablet less effective.

How to manage the interaction:
Although taking Phenytoin and Normendo 5mg Tablet together can result in an interaction, it can be taken if your doctor has prescribed it. If you experience any symptoms, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
NorethisteroneAmprenavir
Severe
How does the drug interact with Normendo 5mg Tablet:
Coadministration of Amprenavir and Normendo 5mg Tablet together may reduce amprenavir effects.

How to manage the interaction:
Combining Amprenavir with Normendo 5mg Tablet can result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No clinically significant food interactions are known with Normendo 5mg Tablet when used as directed. 

NORETHISTERONE-5MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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NORETHISTERONE-5MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Consuming Grapefruit juice may increase the blood levels of Normendo 5mg Tablet. Avoid or limit the consumption of grapefruit and grapefruit juice while taking the Normendo 5mg Tablet dose. Avoid or limit the consumption of grapefruit and grapefruit juice while taking the Normendo 5mg Tablet dose.

All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[PROGESTIN]

FAQs

Normendo 5mg Tablet is used to treat heavy, painful, or irregular periods, premenstrual syndrome (PMS), and endometriosis. Additionally, Normendo 5mg Tablet may be used in the treatment of breast cancer.
Normendo 5mg Tablet contains Norethisterone, a synthetic hormone that mimics the activity of the natural hormone progesterone. Thereby, it restores hormone levels in the body and regulates the growth and shedding of the womb lining. Thus, it helps to treat menstrual disorders.
Normendo 5mg Tablet may be used to delay periods. Normendo 5mg Tablet keeps progesterone levels high and prevents shedding of the womb lining. However, please consult a doctor before using Normendo 5mg Tablet.
Normendo 5mg Tablet may increase the risk of a blood clot in the veins of the leg, especially if you are overweight, smoke, or have a history of a blood clot in the lungs or veins, repeated miscarriage or have major surgery, serious injury, or systemic lupus erythematosus (autoimmune disease). Therefore, please inform your doctor if you have any of these conditions before taking Normendo 5mg Tablet.
You are not recommended to take Normendo 5mg Tablet with rifampicin as it may decrease the levels of Normendo 5mg Tablet in blood and reduce its effectiveness. However, please consult a doctor before taking Normendo 5mg Tablet with other medicines.
Periods usually resume within 3 days of discontinuing Normendo 5mg Tablet. However, please consult a doctor if you have any concerns regarding this.
Normendo 5mg Tablet may cause changes in blood sugar levels. Therefore, it is advised to regularly monitor blood sugar levels while taking Normendo 5mg Tablet and inform your doctor if you have diabetes before taking Normendo 5mg Tablet.
No, Normendo 5mg Tablet is not a contraceptive on its own.
No, Normendo 5mg Tablet is unlikely to cause weight loss.
The recommended dosage can vary greatly depending on the reason for taking the medication. It's crucial to follow your doctor's instructions precisely. Taking an incorrect dosage can lead to ineffective treatment or adverse side effects.
No, Normendo 5mg Tablet does not cause miscarriages. However, it is not safe to take Normendo 5mg Tablet during pregnancy.
Normendo 5mg Tablet can generally be taken either before or after a meal. There is no strict requirement regarding the timing of food intake.
Normendo 5mg Tablet contains Norethisterone, a second-generation progestin.
The duration of Normendo 5mg Tablet use can vary depending on the specific medical condition being treated.
Yes, Normendo 5mg Tablet treats irregular menstrual cycles.
Even after taking Normendo 5mg Tablet and having unprotected sex, one can get pregnant. However, Normendo 5mg Tablet is a category X pregnancy drug. It is not recommended for use during pregnancy as it may harm the unborn baby. Please consult a doctor if you are pregnant or planning for pregnancy.
Common side effects of Normendo 5mg Tablet may cause unusual vaginal bleeding or spotting, dizziness, dry mouth, constipation, nausea, diarrhoea, headache, breast pain, and tenderness. Most of these side effects of Normendo 5mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Yes, Normendo 5mg Tablet can lead to weight gain in some persons. However, it's crucial to remember that this isn't a common adverse effect. The potential risk of weight gain varies based on the individual and the dosage. Talk to your doctor or pharmacist if you are concerned about weight gain or have any other questions regarding norethisterone acetate. They can provide personalized information based on your circumstances.
Limited research is available. Seek medical attention from your doctor if you have any questions. Remember that self-medication can be risky. Always consult with a healthcare professional for proper diagnosis and treatment.
Yes, bleeding may occasionally occur while taking Normendo 5mg Tablet. If you're experiencing bleeding while on Normendo 5mg Tablet and you're concerned, it's important to consult with your healthcare provider. They can determine if the bleeding is normal or if there's another underlying issue.
Normendo 5mg Tablet usually stops irregular bleeding within a few days, but this varies from person to person. If bleeding persists or worsens, consult your doctor.
The duration of Normendo 5mg Tablet use depends on your specific medical condition and the reason for taking it.
The exact dosage and schedule for Normendo 5mg Tablet will vary based on your individual health needs. It is important to follow your doctor's instructions to ensure effective treatment and minimize side effects.
If you forget a dose of Normendo 5mg Tablet, take it as soon as possible. If it's been more than 12 hours, skip the missed dose and continue with your regular schedule or as directed by the physician.
Yes, Normendo 5mg Tablet can interact with other medications. It's important to avoid taking Normendo 5mg Tablet with any medications without consulting your doctor first. They can assess the potential risks and benefits and recommend alternative treatments if necessary.
Store in a cool and dry place away from sunlight. Keep Normendo 5mg Tablet out of reach and out of sight to children.
Normendo 5mg Tablet can be used to treat long-term disorders like endometriosis. But you should talk to your doctor about the long-term advantages and risks.
There is no direct drug interaction between alcohol and Normendo 5mg Tablet. However, heavy alcohol consumption can stress your liver and worsen side effects like headache or nausea. It is best to limit alcohol intake while taking this medicine. Talk to your doctor for further guidance.
This medicine is generally not recommended for breastfeeding mothers, as small amounts of the hormone can pass into breast milk and may affect milk production. Always consult your doctor or pharmacist to discuss safer alternatives.
Yes, it is generally safe to take common over-the-counter painkillers like ibuprofen or paracetamol alongside Normendo 5mg Tablet to manage menstrual cramps or headaches. However, it is always a good practice to talk to your doctor or pharmacist before combining any medications.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Plot No. 294, 1st Floor, Industrial Area Phase 2, Panchkula - 134113 , Haryana , India
Other Info - NO40483
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