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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Nulet-5 Tablet is used to treat mood disorders like schizophrenia, irritability linked with autism, and Tourette's syndrome. Besides this, it also helps in managing mental depression along with other antidepressant medicines. It contains Aripiprazole, which stabilizes and blocks the dopamine and serotonin receptors in the brain, preventing their overactivity, thereby controlling the positive symptoms like hallucinations, misbeliefs, and unfriendly characteristics of schizophrenia. It improves the activity of dopamine and serotonin receptors in other areas of the brain. It helps control negative symptoms (like lack of emotion, social isolation, poor attention, and memory loss) of schizophrenia. Thus, it improves mood swings, depression, and other psychotic problems. Some people may experience drowsiness, headache, tiredness, akathisia (an inability to sit still), difficulty sleeping, lightheadedness, indigestion, shaking, blurred vision, nausea, vomiting, anxiety, and increased saliva production.

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Whats That

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Composition :

ARIPIPRAZOLE-5MG

Manufacturer/Marketer :

Alteus Biogenics Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Nulet-5 Tablet

 Nulet-5 Tablet is an antipsychotic medicine used to treat mood disorders like schizophrenia, irritability linked with autism, and Tourette's syndrome. Besides this, Nulet-5 Tablet also helps in managing mental depression along with other antidepressant medicines. Schizophrenia affects the ability of a person to feel, think and behave clearly. Tourette's syndrome is a mental disorder characterised by uncontrollable, repetitive movements or unwanted sounds (tics). Psychosis may be caused by disturbances in chemical messenger activity known as neurotransmitters (like dopamine and serotonin) in the brain.

Nulet-5 Tablet contains Aripiprazole, which stabilises and blocks the dopamine and serotonin receptors in the brain, preventing their overactivity, thereby controlling the symptoms like hallucinations, misbeliefs, and unfriendly characteristics of schizophrenia. Nulet-5 Tablet improves the activity of dopamine and serotonin receptors in other areas of the brain. It helps control negative symptoms (like lack of emotion, social isolation, poor attention, and memory loss) of schizophrenia. Thus, Nulet-5 Tablet improves mood swings, depression, and other psychotic problems. 

Take Nulet-5 Tablet as prescribed. Your doctor will advise you on how often to take Nulet-5 Tablet , based on your medical condition. Some people may experience drowsiness, headache, tiredness, akathisia (an inability to sit still), difficulty sleeping, lightheadedness, indigestion, shaking, blurred vision, nausea, vomiting, anxiety, and increased saliva production. Most of these side effects of Nulet-5 Tablet do not require medical attention and typically resolve on their own over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Nulet-5 Tablet or any other medicines, please tell your doctor. Nulet-5 Tablet should be used with caution in elderly patients above 65 years of age. There is an increased risk of adverse reactions, including dizziness, difficulty moving and maintaining balance, orthostatic hypotension (a drop in blood pressure when standing up), and drowsiness. Avoid taking Nulet-5 Tablet if you are pregnant or breastfeeding, and consult a doctor. Nulet-5 Tablet is not recommended for children below 13 years of age. If you have any self-harming thoughts or behaviour while taking Nulet-5 Tablet , please get in touch with a doctor immediately. If you have diabetes, abnormal blood pressure, high cholesterol, fits, involuntary muscle movements, especially in the face, attention-deficit hyperactivity disorder (ADHD), blood clots, a history of stroke or heart attack, kidney or liver problems, inform your doctor before taking Nulet-5 Tablet .

Uses of Nulet-5 Tablet

Nulet-5 Tablet is primarily used in the treatment of schizophrenia. Its specific uses are as follows:<br/> • Schizophrenia: Nulet-5 Tablet is used to treat schizophrenia in adults and children aged 13 years and older. It helps manage negative symptoms of schizophrenia, such as lack of emotion, social isolation, poor attention, and memory loss.<br/> • Bipolar I Disorder (Manic Depression): Nulet-5 Tablet is used alone or in combination with mood stabilizers (like valproate or lithium) to treat acute episodes of mania (abnormally elevated mood) in adults and children aged 10 years and older. It helps stabilize mood and reduce irritability and hyperactivity.<br/> • Major Depressive Disorder (MDD) - As Adjunctive Therapy: Nulet-5 Tablet is used in combination with antidepressants to treat MDD when antidepressants alone are not effective. It helps improve mood, energy levels, and overall functioning.<br/> • Tourette Syndrome (TS): Nulet-5 Tablet is used to reduce the severity and frequency of tics (sudden, uncontrollable vocal sounds or movements) in children over 6 years with TS.<br/> • Autism Spectrum Disorder (ASD): Nulet-5 Tablet is used to manage the symptoms of ASD in children over 6 years, such as mood swings, irritability, aggression, tantrums, and self-injurious behaviour.<br/> • Maintenance Treatment: Nulet-5 Tablet is used for long-term management of schizophrenia and bipolar disorder to prevent relapse or worsening of symptoms.<br/>

Directions for Use

  • Nulet-5 Tablet can be taken with or without food, as advised by the doctor.
  • It is usually taken once daily or as prescribed by your doctor.
  • Swallow Nulet-5 Tablet as a whole with a glass of water.
  • Do not crush, chew, or break it.

Medicinal Benefits

Nulet-5 Tablet contains Aripiprazole, which helps treat various psychotic conditions like schizophrenia, mood disorders (such as mania and bipolar disorder), and sometimes depression. Nulet-5 Tablet inhibits the dopamine receptor in our brain, thereby controlling the positive symptoms (like hallucinations, misbelief, and unfriendliness) and negative symptoms (like social isolation, lack of emotion, poor attention, and memory loss) of schizophrenia. Thus, Nulet-5 Tablet improves overall behaviour and thoughts, helping people lead a better social life and comfortably perform daily activities. Nulet-5 Tablet may be used in combination with other medicines to treat depression. Additionally, Nulet-5 Tablet is also used to reduce the severity of unwanted sounds (tics) in Tourette's syndrome (a nervous system problem that causes unwanted sounds or sudden movements).

How Nulet-5 Tablet Works

Nulet-5 Tablet contains Aripiprazole, which stabilises and blocks the dopamine and serotonin receptors in the brain, preventing their overactivity, thereby controlling the positive symptoms like hallucinations, misbeliefs, and unfriendly characteristics of schizophrenia. Nulet-5 Tablet improves the activity of dopamine and serotonin receptors in other areas of the brain. It helps control negative symptoms (like lack of emotion, social isolation, poor attention, and memory loss) of schizophrenia. Thus, Nulet-5 Tablet improves mood swings, depression, and other psychotic problems.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Nulet-5 Tablet
Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:
  • Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
  • Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
  • Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
  • Try relaxing techniques like deep breathing, mindfulness meditation and any others.
  • Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
  • Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
  • Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.
Managing back pain as a side effect of medication requires a combination of self-care techniques, lifestyle modifications, and medical interventions. Here are the steps:
  • Talk to your doctor about your back pain and potential medication substitutes or dose changes.
  • Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
  • To lessen the tension on your back, sit and stand upright and maintain proper posture.
  • To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
  • Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
  • Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
  • To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
  • Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
  • Back discomfort can worsen by bending, twisting, and heavy lifting.
  • Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce irritation.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin soothing.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
  • Restlessness is related to mental health and needs medical attention if it's severe.
  • Regular practice of meditation and yoga can help calm your mind. This can reduce restlessness.
  • Prevent smoking as it can impact your calmness of body and mind.
  • Talk to your friends and family about restlessness, who can provide a solution for why you feel restless.
  • Get sufficient sleep for a minimum of 6-7 hours to reduce restlessness.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
  • Restlessness is related to mental health and needs medical attention if it's severe.
  • Regular practice of meditation and yoga can help calm your mind. This can reduce restlessness.
  • Prevent smoking as it can impact your calmness of body and mind.
  • Talk to your friends and family about restlessness, who can provide a solution for why you feel restless.
  • Get sufficient sleep for a minimum of 6-7 hours to reduce restlessness.

What if I have taken an overdose of Nulet-5 Tablet

Do not take more than the prescribed dose of Nulet-5 Tablet , as it may cause an overdose. Symptoms of an overdose may include confusion, tremors, drowsiness, vomiting, aggression, fast or slow heart rate, seizure (convulsions), weak or shallow breathing, fainting, or coma. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

If you are allergic to Nulet-5 Tablet or any other medicines, please tell your doctor. Nulet-5 Tablet should be used with caution in elderly patients above 65 years of age, as there is an increased risk of adverse reactions, including dizziness, changes in mobility and balance, orthostatic hypotension (a drop in blood pressure when standing up), and drowsiness. Avoid taking Nulet-5 Tablet if you are pregnant or breastfeeding, and consult a doctor. Nulet-5 Tablet is not recommended for children below 13 years of age. If you have any self-harming thoughts or behaviour while taking Nulet-5 Tablet , please get in touch with a doctor immediately. If you develop impulse control disorders such as excessive eating, spending, addictive gambling, or abnormally high sex drive, inform your doctor so that the dose may be adjusted appropriately, or you are advised to stop taking Nulet-5 Tablet . If you have diabetes, abnormal blood pressure, high cholesterol, fits, involuntary muscle movements especially in the face, attention-deficit hyperactivity disorder (ADHD), blood clots, history of stroke or heart attack, kidney or liver problems, inform your doctor before taking Nulet-5 Tablet .

Drug-Drug Interactions

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AripiprazoleOxycodone
Severe

Drug-Drug Interactions

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How does the drug interact with Nulet-5 Tablet:
Co-administration of Metoclopramide with Nulet-5 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Nulet-5 Tablet with Metoclopramide is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AripiprazoleOxycodone
Severe
How does the drug interact with Nulet-5 Tablet:
Using Nulet-5 Tablet together with Oxycodone can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Taking Nulet-5 Tablet with Oxycodone together can result in an interaction, but it can be taken if a doctor has advised it. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Furthermore, because these medications may induce dizziness, sleepiness, trouble focusing, and impairment in judgement, response speed, and motor coordination, you should avoid driving or operating dangerous machinery. Do not stop using any medications without a doctor's advice.
AripiprazolePethidine
Severe
How does the drug interact with Nulet-5 Tablet:
Using Nulet-5 Tablet together with Pethidine can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although there is a possible interaction between Pethidine and Nulet-5 Tablet, you can take these medicines together if prescribed by a doctor. Consult a doctor if you experience dizziness, drowsiness, difficulty concentrating, impaired judgment, reaction speed, and motor coordination. Do not discontinue any medications without consulting a doctor.
AripiprazoleEsketamine
Severe
How does the drug interact with Nulet-5 Tablet:
Using Esketamine together with Nulet-5 Tablet may increase side effects (drowsiness, confusion, difficulty concentrating, and impairment in thinking, judgment, reaction speed, and motor coordination).

How to manage the interaction:
Taking Nulet-5 Tablet with Esketamine together can result in an interaction, but it can be taken if a doctor has advised it. If you're having any of these symptoms like feeling sleepy, having trouble concentrating, or feeling confused, it's important to let your doctor know right away. They may be able to recommend other options for you that won't cause these problems. Do not stop using any medications without talking to a doctor.
How does the drug interact with Nulet-5 Tablet:
Using Nulet-5 Tablet together with Nalbuphine can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Co-administration of Nulet-5 Tablet with Nalbuphine can result in an interaction, but it can be taken if a doctor has advised it. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Furthermore, because these medications may induce dizziness, sleepiness, trouble focusing, and impairment in judgement, response speed, and motor coordination, you should avoid driving or operating dangerous machinery. Do not stop using any medications without a doctor's advice.
How does the drug interact with Nulet-5 Tablet:
Using Nulet-5 Tablet together with Fentanyl can cause central nervous system depression (a condition that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Taking Nulet-5 Tablet with Fentanyl together can result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms - trouble breathing, feeling tired, or difficulty concentrating - contact a doctor immediately. Do not stop using any medications without a doctor's advice.
AripiprazoleIomeprol
Severe
How does the drug interact with Nulet-5 Tablet:
Coadministration of Nulet-5 Tablet and Iohexol may increase the risk of seizure (a sudden, violent, uncontrollable contraction of a group of muscles).

How to manage the interaction:
Although there is a possible interaction between Nulet-5 Tablet and Iomeprol, you can take these medicines together if prescribed by a doctor. If you have seizures or a head injury, it's important to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Nulet-5 Tablet:
Taking carbamazepine and Nulet-5 Tablet together can reduce the effects of Nulet-5 Tablet which may make the medication less effective.

How to manage the interaction:
Taking carbamazepine and Nulet-5 Tablet together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Nulet-5 Tablet:
Using Nulet-5 Tablet together with Codeine can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Nulet-5 Tablet and Codeine together can cause an interaction, it can be taken if a doctor has suggested it. However, if you notice trouble breathing, feeling too sleepy or dizzy, having trouble focusing, consult a doctor right away. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Do not stop using any medications without talking to a doctor.
AripiprazoleHydrocodone
Severe
How does the drug interact with Nulet-5 Tablet:
Using Nulet-5 Tablet together with Hydrocodone can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Nulet-5 Tablet and Hydrocodone together can cause an interaction, it can be taken if a doctor has suggested it. If you have any of these symptoms like trouble breathing, feeling very sleepy, or having trouble focusing, it's important to call a doctor right away. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Limit the intake of caffeine as it may reduce the effectiveness of Nulet-5 Tablet .
  • Eat plenty of fruits and vegetables. Eat more fish, especially oily fish such as salmon, sardines, trout, mackerel, pilchards, and herring.
  • Cut down sugars, salt, and saturated fats.
  • Drink adequate water to keep the body hydrated.
  • Engage in regular exercise and maintain a stable weight, as Nulet-5 Tablet may contribute to weight gain.
  • Avoid alcohol consumption, as it may increase drowsiness.

Habit Forming

No

Therapeutic Class

ANTIPSYCHOTICS
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Alcohol

Unsafe

Avoid alcohol consumption while taking Nulet-5 Tablet , as it may increase the risk of side effects such as dizziness, drowsiness, or difficulty concentrating.

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Pregnancy

Unsafe

Nulet-5 Tablet is a Category C pregnancy drug. It is not recommended for use during pregnancy, especially in the third trimester, as it may cause extrapyramidal and/or withdrawal symptoms in newborn babies.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Nulet-5 Tablet , as it may be excreted in breast milk and cause adverse effects in the baby.

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Driving

Unsafe

Nulet-5 Tablet may cause dizziness or vision problems, such as blurred vision. Therefore, avoid driving if you feel dizzy or have vision disturbances after taking Nulet-5 Tablet .

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Liver

Caution

Take Nulet-5 Tablet with caution, especially if you have a history of liver disease. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Nulet-5 Tablet with caution, especially if you have a history of kidney disease. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Nulet-5 Tablet is not recommended for children below 13 years due to the increased risk of adverse effects. However, please consult a doctor before giving Nulet-5 Tablet to children.

Have a query?

FAQs

Nulet-5 Tablet is used to treat mood disorders like schizophrenia, irritability linked with autism, and Tourette's syndrome. Besides this, it also helps in managing mental depression along with other antidepressant medicines.

Nulet-5 Tablet contains Aripiprazole, an antipsychotic that works by inhibiting the dopamine receptors in the brain and preventing their overactivity. Thereby, helps in controlling the positive symptoms (such as hallucinations, misbeliefs and unfriendliness) of schizophrenia. Also, Nulet-5 Tablet improves the activity of dopamine receptors in other areas of the brain and helps in controlling negative symptoms (such as social isolation, lack of emotion, poor attention and memory loss) of schizophrenia. Therefore, Nulet-5 Tablet improves behaviour, thoughts, and helps in having a better social life, enabling one to comfortably perform daily activities.

No, you are not recommended to take Nulet-5 Tablet with ibuprofen as co-administration of these medicines may increase the risk of fits and increase the levels of Nulet-5 Tablet in the blood, leading to increased adverse effects. However, please consult a doctor before taking Nulet-5 Tablet with other medicines.

Nulet-5 Tablet may cause weight gain in some patients, but it is not a necessary side effect for everyone taking Nulet-5 Tablet . However, to avoid gaining weight while taking Nulet-5 Tablet , it is advisable to engage in regular exercise and limit high-calorie drinks. Instead, opt for non-alcoholic beverages, herbal tea, and lemon water.

Nulet-5 Tablet is not recommended for dementia (loss of memory or other mental abilities) patients, especially in elderly people, as it may cause severe adverse effects, including stroke. Therefore, it is advised to inform your doctor if you have dementia or a history of stroke before taking Nulet-5 Tablet .

Yes, Nulet-5 Tablet may cause high blood sugar levels. Therefore, regular monitoring of blood sugar levels is recommended while taking Nulet-5 Tablet and inform your doctor if you have diabetes before taking Nulet-5 Tablet . However, if you experience dry mouth, increased thirst or urination, or a fruity breath odour, please consult a doctor, as these may be signs of high blood sugar.

No, you are not recommended to stop taking Nulet-5 Tablet without consulting your doctor, as it may worsen the condition or cause recurring symptoms. Therefore, take Nulet-5 Tablet for as long as your doctor has prescribed it. If you experience any difficulty while taking Nulet-5 Tablet , please consult your doctor so that the dose can be gradually reduced.

Yes, Nulet-5 Tablet is a mood stabiliser. It helps calm the mood and treats mood-related problems.

Nulet-5 Tablet might start working within a few days or weeks. However, you may notice the full benefits of Nulet-5 Tablet after 2-3 months. Continue taking Nulet-5 Tablet for the prescribed duration to prevent the recurrence of symptoms.

Nulet-5 Tablet may cause priapism (prolonged and painful erection) in some people. Please consult the doctor if you have any concerns.

Elderly patients more than 65 years old with dementia-related psychosis treated with Nulet-5 Tablet can be at an increased risk of death. Increased risk of suicidal thinking and behaviour changes has been observed in children, adolescents, and young adults taking Nulet-5 Tablet , so close monitoring for worsening and the emergence of suicidal thoughts and behaviours is required.

Avoid intake of grapefruit juice with Nulet-5 Tablet as it may reduce the effect of Nulet-5 Tablet . Also, avoid alcohol consumption with Nulet-5 Tablet as it may increase the risk of side effects such as dizziness, drowsiness or difficulty in concentrating. Do not drive if you feel dizzy or have vision disturbances after taking Nulet-5 Tablet .

Consult the doctor if you are diabetic, as Nulet-5 Tablet may cause high blood sugar levels. Regular monitoring of blood glucose levels is advised.

Nulet-5 Tablet may cause side effects like drowsiness, headache, tiredness, akathisia (inability to sit still), difficulty sleeping, light-headedness, indigestion, shaking, blurred vision, nausea, vomiting, anxiety, and increased saliva production. Most of these side effects of Nulet-5 Tablet do not require medical attention and typically resolve on their own over time. However, if the side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Alteus Biogenics Pvt. Ltd., 14-B Dover Lane, Kolkata - 700029, Wb, India.
Other Info - NUL0085

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