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compositionComposition:OTILONIUM BROMIDE-40MG
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Prescription Medicine
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Obgram-40 Tablet is used to treat irritable bowel syndrome (IBS) and other gastrointestinal conditions associated with abnormal gut movements, painful bowel spasms and abdominal distension (swelling or bloating in the belly area). It helps relieve symptoms such as abdominal pain, spasms, cramps, bloating, and irregular bowel habits by relaxing the intestinal muscle.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

OTILONIUM BROMIDE-40MG

Manufacturer/Marketer :

Ingram Biosciences Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Obgram-40 Tablet

Obgram-40 Tablet is a prescription medication used to relieve painful muscle spasms and cramps in the digestive tract. It is most commonly prescribed to treat the symptoms of irritable bowel syndrome (IBS). By relaxing the muscles of your gut, this medicine helps reduce abdominal discomfort and bloating.

To achieve the best results, you should take Obgram-40 Tablet consistently and exactly as prescribed by your medical professional. This medicine is typically taken with a glass of water about 20 to 30 minutes before your meals. Combining this treatment with simple lifestyle adjustments, such as eating smaller portions and managing daily stress, can significantly improve your overall results.

Some people may experience mild side effects, such as a dry mouth, mild nausea, or light dizziness. While these symptoms are usually harmless, you must contact your doctor immediately if you notice severe allergic reactions, swelling of the face, or difficulty breathing.

Talk to your doctor before taking Obgram-40 Tablet if you have glaucoma (particularly narrow-angle glaucoma), an enlarged prostate, gastrointestinal obstruction, or other significant medical conditions to ensure this medicine is appropriate for you. Do not take this if you have a known allergy to this medication or if you suffer from a severe blockage in your digestive system.

This medicine may interact with other treatments, and drinking alcohol while taking it should be avoided as it can increase dizziness. Pregnant women, breastfeeding mothers, and elderly patients should consult their doctor before starting Obgram-40 Tablet to ensure it is safe for their specific health needs.

Uses of Obgram-40 Tablet

The following are the common conditions for which Obgram-40 Tablet is prescribed: 

  • Irritable Bowel Syndrome (IBS): Obgram-40 Tablet helps by relaxing hyperactive gut muscles, reducing painful stomach cramps, bloating, and unpredictable bowel habits.
  • Digestive tract spasms: Obgram-40 Tablet relieves painful, sudden muscle contractions in the stomach and intestines.

Key Benefits

Obgram-40 Tablet provides targeted relief directly to your digestive tract, helping you return to your daily activities without the constant worry of sudden stomach pain. By calming the overactive muscles in your abdomen, this medicine allows you to eat and move more comfortably.

Key benefits include:

  • Easing of painful, sudden stomach cramps and squeezing sensations
  • Reduction of abdominal bloating and pressure by allowing trapped gas to pass more easily
  • Improved daily comfort and freedom from the unpredictable pain associated with gut spasms
Side effects of Obgram-40 Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.

Directions for Use

  • Obgram-40 Tablet can be taken on an empty stomach, preferably 20 minutes before a meal or as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Obgram-40 Tablet as a whole with a glass of water.
  • Do not chew, crush, or break it.

How Obgram-40 Tablet Works

Obgram-40 Tablet contains otilonium bromide, an antispasmodic medicine that helps relieve painful muscle spasms in the stomach and intestines associated with digestive disorders such as irritable bowel syndrome (IBS). Obgram-40 Tablet works through two complementary mechanisms. It blocks the entry of calcium into the smooth muscle cells of the digestive tract, reducing the muscle contractions responsible for intestinal spasms. It also has mild antimuscarinic (anticholinergic) activity, which further helps relax overactive intestinal muscles and relieve abdominal cramping. Since it acts mainly within the digestive tract, where it selectively reduces excessive intestinal contractions while helping preserve normal digestive function. By selectively reducing excessive intestinal contractions rather than completely stopping normal bowel movement, it helps relieve abdominal pain, cramps, bloating, and discomfort associated with digestive spasms.
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Alcohol

Caution

The interaction of Obgram-40 Tablet with alcohol is unknown. Please consult a doctor before consuming alcohol while using Obgram-40 Tablet .

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Pregnancy

Caution

Please consult a doctor if you are pregnant. Obgram-40 Tablet is given to pregnant women only if the doctor thinks the benefits are greater than the risks.

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Breast Feeding

Caution

It is unknown whether Obgram-40 Tablet is excreted in human milk. Therefore, Obgram-40 Tablet is given to breastfeeding mothers only if the doctor thinks the benefits are greater than the risks.

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Driving

Safe if prescribed

Obgram-40 Tablet usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Take Obgram-40 Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Obgram-40 Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Obgram-40 Tablet is not recommended for children below 18 years of age, as the safety and effectiveness have not established.

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Heart

Caution

Please inform your doctor if you have a history of heart disease before taking Obgram-40 Tablet . Your doctor will prescribe it only if the potential benefits outweigh the possible risks.

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Geriatrics

Caution

Obgram-40 Tablet should be used in elderly patients only when prescribed by a doctor. If you have any concerns about using Obgram-40 Tablet for geriatrics, please consult a doctor.

What if I have taken an overdose of Obgram-40 Tablet

If you suspect an overdose or have taken more than the prescribed amount, seek immediate medical attention or contact your local poison control centre right away, even if you do not feel any symptoms.

Diet & Lifestyle Advise

  • Identify trigger foods: Keep a daily food journal to track what you eat and note any foods—such as fatty dishes, caffeine, carbonated beverages, or spicy foods—that seem to trigger your stomach spasms.
  • Adjust your meal sizes: Try eating smaller, more frequent meals throughout the day rather than three large meals, as this places less strain on your digestive tract.
  • Manage daily stress: Since stress directly impacts gut contractions, practise relaxation techniques such as deep breathing exercises, gentle yoga, or meditation.
  • Incorporate soluble fibre: Gradually add foods rich in soluble fibre, like oats and barley, to your diet to help stabilise your bowel movements.
  • Stay hydrated: Drink adequate amounts of water throughout the day to support healthy digestion and keep your bowel movements regular.
health query

Have a query?

How Soon It Starts Working

  • The time required for Obgram-40 Tablet to start to work: Obgram-40 Tablet ideally shows its action within 30 minutes to 1 hour after administration.
  • The time for which the effects of Obgram-40 Tablet last: The effect of Obgram-40 Tablet lasts for 4 to 8 hours.

What if you forget to take Obgram-40 Tablet

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a forgotten tablet.

Storage

• Store Obgram-40 Tablet tablets at room temperature, strictly between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Inspect the packaging before use: Always check the blister pack before taking a tablet. Do not use the medication if the foil is punctured or damaged.
  • Be cautious with activities requiring alertness: Avoid driving, operating machinery, or performing tasks that require mental alertness if you experience dizziness after taking Obgram-40 Tablet .
  • Do not share your medication: Never share Obgram-40 Tablet with anyone else, even if they have symptoms similar to yours.
  • Inform healthcare professionals before procedures: Tell your dentist, surgeon, or any other healthcare provider that you are taking Obgram-40 Tablet before undergoing any medical or dental procedures.
  • Monitor your response to treatment: Consult your doctor if your gut spasms and stomach pain do not begin to improve after a few weeks of consistent use.

Drug-Drug Interactions

verifiedApollotooltip

The following medicines may interact with Obgram-40 Tablet and affect how it works or increase the risk of side effects: 

  • Anticholinergic drugs: Combining Obgram-40 Tablet with other medications that have anticholinergic properties (such as certain antihistamines or antidepressants) may increase the risk of dry mouth, constipation, and blurred vision.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

verifiedApollotooltip

The following foods or dietary habits may influence how Obgram-40 Tablet works in your body: 

  • High-fat meals: Taking this medication with very high-fat meals may delay the absorption and onset of action of Obgram-40 Tablet . It is best taken on an empty stomach, about 20 to 30 minutes before eating.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTISPASMODICS]

FAQs

Obgram-40 Tablet is used to treat irritable bowel syndrome (IBS) and other gastrointestinal conditions associated with abnormal gut movements, painful bowel spasms and abdominal distension (swelling or bloating in the belly area).
Obgram-40 Tablet contains Otilonium bromide, an antispasmodic that works by relaxing the muscles of the intestinal walls. Thus, it provides relief from IBS symptoms such as abdominal pain, spasms, cramps, bloating, and irregular bowel habits.
Obgram-40 Tablet should be used with caution in glaucoma patients as it may worsen the condition. Therefore, if you have glaucoma, please inform your doctor before taking Obgram-40 Tablet .
Dizziness may be a side effect of Obgram-40 Tablet . However, if the condition persists or worsens, please consult a doctor.
Obgram-40 Tablet reduces stomach pain, which is a symptom of irritable bowel syndrome. Obgram-40 Tablet is an antispasmodic agent that reduces spasms, cramps and stomach pain. However, please consult a doctor before taking Obgram-40 Tablet .
Obgram-40 Tablet should be used with caution in people with an enlarged prostate gland, as it may increase the risk of severe adverse effects. Therefore, if you have an enlarged prostate gland, inform your doctor before taking Obgram-40 Tablet .
It is highly recommended to take Obgram-40 Tablet on an empty stomach, approximately 20 to 30 minutes before your meals. Taking it with food may delay its effectiveness. Talk to your doctor or pharmacist if you have questions about timing.
The safety of this medicine during pregnancy has not been fully established. It is recommended to avoid taking Obgram-40 Tablet if you are pregnant unless your doctor specifically decides it is necessary. Talk to your doctor before using this medicine during pregnancy.
Your doctor will determine how long you should take Obgram-40 Tablet based on your symptoms and response to the treatment. Do not use this medicine for longer than prescribed without medical advice. Talk to your doctor about your treatment duration.
Dry mouth is a known mild side effect. Sucking on sugar-free candies, chewing sugar-free gum, or taking frequent sips of water can help relieve this discomfort. Talk to your doctor or pharmacist if the dry mouth is severe.
It is best to limit or avoid alcohol while taking this medicine. Alcohol can increase the risk of side effects like dizziness and drowsiness. Talk to your doctor or pharmacist for personalised safety advice.
No, Obgram-40 Tablet is specifically prescribed for spasms and cramps related to conditions like irritable bowel syndrome (IBS). It is not designed to treat general indigestion, heartburn, or stomach ulcers. Talk to your doctor for an accurate diagnosis of your stomach symptoms.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. U.S. Food and Drug Administration (FDA). Spasmomen Otilonium Bromide 40Mg Tablets Pil [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  2. U.S. Food and Drug Administration (FDA). Otilonium Bromide 40 Mg Film Coateds Spasmomen A. Menarini Industrie Farmaceutiche Riunite Srl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  3. MIMS Drug Reference Compendium. Otilonium Bromide Monograph. Singapore: MIMS; 2025. [Accessed on 02 Jun. 2026]Check here
  4. Evangelista S, Traini C, Vannucchi MG Otilonium Bromide: A Drug with a Complex Mechanism of Action. Curr Pharm Des. 2018;24(16):1772-1779Check here
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed on 28 Mar. 2019]Check here
  6. Doralin 40 Mg Film Coated Tablets (Otilonium Bromide). [Accessed on 02 Jun. 2026]Check here

Country of origin

India

Manufacturer/Marketer address

Corp. Off. : Ar-1, Office No-D/126,Sector-3,Airoli,New Mumbai-400708
Other Info - OBG0002

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