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compositionComposition:NORETHISTERONE-10MG
prescription
Prescription Medicine
info
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Offday CR 10 Tablet 10's is used to treat heavy, painful, or irregular periods, premenstrual syndrome (PMS), and endometriosis. Additionally, it may be used in the treatment of breast cancer. It contains Norethisterone, which works by restoring the hormone levels in the body. In some cases, this medicine may cause side effects such as unusual vaginal bleeding or spotting, dizziness, dry mouth, constipation, nausea, and diarrhoea. Let the doctor know if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

NORETHISTERONE-10MG

Manufacturer/Marketer :

Wellesta Healthcare Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Offday CR 10 Tablet 10's

Offday CR 10 Tablet 10's is an oral prescription medication used to manage heavy periods, painful menstruation, and irregular cycles. It is also commonly prescribed to treat endometriosis and to temporarily delay the onset of a period. By regulating hormone levels in your body, this medicine helps restore a manageable and predictable menstrual cycle.

For best results, you must take Offday CR 10 Tablet 10's consistently at the same time each day as directed by your healthcare provider. You can take this tablet with or without food, though taking it with a glass of water is recommended. Incorporating a balanced diet and regular, moderate exercise can further support your body's hormonal balance and improve your treatment results.

While taking Offday CR 10 Tablet 10's, you may experience mild, temporary side effects such as nausea, headaches, or breast tenderness. Most of these symptoms subside as your body adjusts, but you should contact your doctor immediately if you experience severe symptoms like sudden chest pain or shortness of breath.

Talk to your doctor before starting this medicine if you have a history of high blood pressure, diabetes, or migraines. Do not take this if you are pregnant, have active liver damage, a history of blood clots, or unexplained vaginal bleeding.

This medication can interact with certain epilepsy treatments, tuberculosis therapies, and herbal supplements, which may reduce how well it works. Avoid smoking while taking Offday CR 10 Tablet 10's, as smoking significantly increases your risk of developing serious blood clots. If you are breastfeeding, elderly, or planning a pregnancy, always consult your doctor or pharmacist before starting treatment.

Uses of Offday CR 10 Tablet 10's

Offday CR 10 Tablet 10's is used to manage heavy periods, painful menstruation, and irregular cycles. The detailed uses of Offday CR 10 Tablet 10's are as follows:

  • Heavy menstrual bleeding: Offday CR 10 Tablet 10's helps control and significantly lighten abnormally heavy or prolonged blood flow during your cycle.
  • Painful periods: It reduces severe cramping, pelvic discomfort, and abdominal pain associated with menstruation.
  • Endometriosis: It works by limiting the abnormal growth of the womb lining outside the uterus, relieving chronic pelvic pain and inflammation.
  • Delaying periods: It temporarily postpones your menstrual cycle for travel, medical procedures, or personal convenience.

Key Benefits

Offday CR 10 Tablet 10's helps manage heavy and painful menstrual periods by reducing excessive bleeding and relieving menstrual discomfort. With regular use, it supports better energy levels, improves daily comfort, and enhances overall quality of life.

  • Controls Heavy Menstrual Bleeding: By reducing excessive blood loss during menstruation, this medicine helps lower the risk of iron deficiency, reducing fatigue and physical weakness while supporting better energy levels.
  • Relieves Menstrual and Pelvic Pain: This medicine helps ease painful menstrual cramps, pelvic discomfort, and lower back pain associated with conditions such as endometriosis, improving comfort throughout your menstrual cycle.
  • Supports an Active Lifestyle: By reducing heavy bleeding and menstrual pain, this medicine helps improve physical mobility, allowing you to carry out your daily activities with greater confidence and comfort.

Directions for Use

  • Offday CR 10 Tablet 10's can be taken with or without food, or as advised by the doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Offday CR 10 Tablet 10's as a whole with a glass of water.
  • Do not chew, crush or break it.

How Offday CR 10 Tablet 10's Works

Offday CR 10 Tablet 10's contains a synthetic version of progesterone, norethisterone, a natural female sex hormone that regulates the monthly menstrual cycle. Under normal conditions, a drop in progesterone levels triggers the shedding of the womb lining, resulting in a period. This medicine works by maintaining steady hormone levels in your body. By mimicking natural progesterone, it prevents the womb lining from growing too quickly or shedding prematurely. This stabilisation helps stop irregular bleeding, lightens heavy cycles, and prevents menstruation entirely for as long as you continue taking the medication under medical supervision.
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Alcohol

Consult your doctor

The interaction of Offday CR 10 Tablet 10's with alcohol is unknown. Please consult a doctor before consuming alcohol while using Offday CR 10 Tablet 10's.

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Pregnancy

Unsafe

Offday CR 10 Tablet 10's is a category X pregnancy drug and is not recommended for use during pregnancy as it may harm the unborn baby. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Consult your doctor

Offday CR 10 Tablet 10's is given to breastfeeding women only if the doctor thinks benefits are greater than risks. Please consult a doctor if you are breastfeeding.

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Driving

Safe if prescribed

Offday CR 10 Tablet 10's usually does not affect your ability to drive or operate machinery.

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Liver

Unsafe

Offday CR 10 Tablet 10's is not recommended if you have liver disease. However, if you have any concerns regarding this, please consult a doctor.

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Kidney

Caution

Take Offday CR 10 Tablet 10's with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Offday CR 10 Tablet 10's is not recommended for use in children under 18 years.

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Heart

Caution

Offday CR 10 Tablet 10's should be used with caution in patients with heart problems. Inform your doctor about any heart-related conditions before taking Offday CR 10 Tablet 10's.

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Geriatrics

Unsafe

Offday CR 10 Tablet 10's is generally not recommended for elderly patients due to an increased risk of side effects and reduced effectiveness.

What if I have taken an overdose of Offday CR 10 Tablet 10's

In case of an accidental overdose, seek immediate medical attention. Symptoms of an overdose may include severe nausea, vomiting, dizziness, or unexpected vaginal bleeding.

Diet & Lifestyle Advise

  • Increase iron-rich foods: If you experience heavy bleeding, eat more spinach, lean red meats, beans, and fortified cereals to help prevent anaemia and fatigue.
  • Stay hydrated: Drink plenty of water throughout the day to help reduce bloating and support overall metabolic function.
  • Engage in gentle exercise: Activities like walking, swimming, or yoga can naturally relieve menstrual cramps, improve pelvic blood flow, and boost your mood.
  • Track your symptoms: Keep a detailed diary of your period dates, bleeding intensity, and any side effects to share with your doctor during follow-up visits.
  • Avoid smoking: Smoking while taking hormone treatments significantly increases the risk of serious cardiovascular complications, including blood clots.
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How Soon It Starts Working

  • The time required for Offday CR 10 Tablet 10's to start to work: The time required for Offday CR 10 Tablet 10's to show its action is unknown.
  • The time for which the effects of Offday CR 10 Tablet 10's last: The duration of action for Offday CR 10 Tablet 10's is clinically unknown.

What if you forget to take Offday CR 10 Tablet 10's

If you miss a dose, take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for a forgotten tablet, as this may increase your risk of side effects. If you are using this medicine to delay your period, a missed dose may cause breakthrough bleeding or spotting.

Storage

•Store Offday CR 10 Tablet 10's oral tablets at room temperature, ideally below 25°C or 30°C. •Keep the tablets in their original packaging to protect them from direct light and moisture.

Drug Warnings

  • Always confirm with your doctor that Offday CR 10 Tablet 10's is safe for you if you have a history of blood clots, heart disease, or liver problems.
  • Do not rely on Offday CR 10 Tablet 10's as a contraceptive unless your doctor has specifically prescribed it for that purpose; use a barrier method like condoms if you need to prevent pregnancy.
  • Stop taking this medicine immediately and contact your doctor if you experience a sudden migraine, visual disturbances, or severe leg pain.
  • Inform your surgeon or dentist that you are taking this medication well in advance of any planned surgeries, as you may need to stop taking it temporarily to lower your risk of blood clots.
  • Check your blood pressure regularly while taking this medication, especially if you have a history of hypertension.

Drug-Drug Interactions

verifiedApollotooltip
  • Epilepsy medications: Taking this medicine with drugs like carbamazepine, phenytoin, or phenobarbital may reduce its effectiveness.
  • Tuberculosis treatments: Rifampicin and rifabutin can speed up how your liver processes Offday CR 10 Tablet 10's, making it less effective.
  • Herbal remedies: St. John’s Wort can lower the levels of this medicine in your body, reducing its ability to control your symptoms.
NorethisteroneAcitretin
Severe
NorethisteronePhenobarbital
Severe

Drug-Drug Interactions

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NorethisteroneAcitretin
Severe
How does the drug interact with Offday CR 10 Tablet:
Coadministration of Acitretin with Offday CR 10 Tablet may interfere with the contraceptive effect of Offday CR 10 Tablet.

How to manage the interaction:
Acitretin and Offday CR 10 Tablet should be used together only if prescribed by your doctor. Use of at least two methods of effective contraception is mandatory during acitretin therapy and for at least 3 years after stopping therapy.
NorethisteronePhenobarbital
Severe
How does the drug interact with Offday CR 10 Tablet:
The combined use of Offday CR 10 Tablet and phenobarbital can reduce the blood levels and effects of Offday CR 10 Tablet.

How to manage the interaction:
Although taking phenobarbital and Offday CR 10 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. If you experience any symptoms like abnormal bleeding, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
NorethisteroneEtretinate
Severe
How does the drug interact with Offday CR 10 Tablet:
Using Etretinate and Offday CR 10 Tablet together can cause severe, birth defects. Never use etretinate if you are pregnant. Both a primary and a secondary form of birth control must be used together and for at least 3 years after stopping therapy.

How to manage the interaction:
Although taking Offday CR 10 Tablet and Etretinate together can cause an interaction, it can be taken if your doctor has suggested it. If you notice any of these signs, make sure to contact your doctor right away. These symptoms may be related to your birth control. Do not stop using any medications without a doctor's advice.
NorethisteroneGriseofulvin
Severe
How does the drug interact with Offday CR 10 Tablet:
Taking griseofulvin with Offday CR 10 Tablet may reduce blood levels and the effects of Offday CR 10 Tablet.

How to manage the interaction:
Although there is a possible interaction between Griseofulvin and Offday CR 10 Tablet, you can take these medicines together if prescribed by a doctor. However, if you experience any of these symptoms like unexpected bleeding or abnormal bleeding, it's important to contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
NorethisteroneTranexamic acid
Severe
How does the drug interact with Offday CR 10 Tablet:
Using tranexamic acid together with norethindrone may increase the risk of blood clots.

How to manage the interaction:
Taking Offday CR 10 Tablet with tranexamic acid can lead to an interaction, however, it can be taken only if a doctor has advised it. If you experience symptoms such as chest pain, shortness of breath, coughing up blood, blood in the urine, sudden loss of vision, and pain, redness, or swelling in your arm or leg, contact a doctor immediately .Do not discontinue any medications without consulting a doctor.
NorethisteroneBosentan
Severe
How does the drug interact with Offday CR 10 Tablet:
Co-administration of Offday CR 10 Tablet with Bosentan can reduce the blood levels and effects of norethindrone.

How to manage the interaction:
Taking Offday CR 10 Tablet with Bosentan together can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to a doctor.
NorethisteroneRifapentine
Severe
How does the drug interact with Offday CR 10 Tablet:
Combining Rifapentine and norethindrone reduces the blood levels and effects of norethindrone and increases the risk of bleeding and unintended pregnancy.

How to manage the interaction:
Although there is a possible interaction between Offday CR 10 Tablet and Rifapentine, you can take these medicines together if prescribed by your doctor. If you're having any of these symptoms like unexpected bleeding, abnormal bleeding, it's important to reach out to a doctor right away. Do not discontinue any medications without consulting a doctor.
NorethisteroneTopiramate
Severe
How does the drug interact with Offday CR 10 Tablet:
Coadministration of Offday CR 10 Tablet with Topiramate can reduce the blood levels and effects of norethindrone in the body. This increases the risk of severe bleeding and unintended pregnancy.

How to manage the interaction:
Taking Offday CR 10 Tablet and topiramate together can result in an interaction; it can be taken if your doctor has advised it. However, if you notice any symptoms of abnormal bleeding, hot flashes or vaginal dryness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
NorethisteronePhenytoin
Severe
How does the drug interact with Offday CR 10 Tablet:
Coadministration of Phenytoin and Offday CR 10 Tablet may decrease the blood levels of Offday CR 10 Tablet, which may make Offday CR 10 Tablet less effective.

How to manage the interaction:
Although taking Phenytoin and Offday CR 10 Tablet together can result in an interaction, it can be taken if your doctor has prescribed it. If you experience any symptoms, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
NorethisteroneAmprenavir
Severe
How does the drug interact with Offday CR 10 Tablet:
Coadministration of Amprenavir and Offday CR 10 Tablet together may reduce amprenavir effects.

How to manage the interaction:
Combining Amprenavir with Offday CR 10 Tablet can result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip

No clinically significant food interactions are known with Offday CR 10 Tablet 10's when used as directed. 

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[PROGESTIN]

FAQs

Offday CR 10 Tablet 10's is used to treat heavy, painful, or irregular periods, premenstrual syndrome (PMS), and endometriosis. Additionally, Offday CR 10 Tablet 10's may be used in the treatment of breast cancer.
Offday CR 10 Tablet 10's contains Norethisterone, a synthetic hormone that mimics the activity of the natural hormone progesterone. Thereby, it restores hormone levels in the body and regulates the growth and shedding of the womb lining. Thus, it helps to treat menstrual disorders.
Offday CR 10 Tablet 10's may be used to delay periods. Offday CR 10 Tablet 10's keeps progesterone levels high and prevents shedding of the womb lining. However, please consult a doctor before using Offday CR 10 Tablet 10's.
Offday CR 10 Tablet 10's may increase the risk of a blood clot in the veins of the leg, especially if you are overweight, smoke, or have a history of a blood clot in the lungs or veins, repeated miscarriage or have major surgery, serious injury, or systemic lupus erythematosus (autoimmune disease). Therefore, please inform your doctor if you have any of these conditions before taking Offday CR 10 Tablet 10's.
You are not recommended to take Offday CR 10 Tablet 10's with rifampicin as it may decrease the levels of Offday CR 10 Tablet 10's in blood and reduce its effectiveness. However, please consult a doctor before taking Offday CR 10 Tablet 10's with other medicines.
Periods usually resume within 3 days of discontinuing Offday CR 10 Tablet 10's. However, please consult a doctor if you have any concerns regarding this.
Offday CR 10 Tablet 10's may cause changes in blood sugar levels. Therefore, it is advised to regularly monitor blood sugar levels while taking Offday CR 10 Tablet 10's and inform your doctor if you have diabetes before taking Offday CR 10 Tablet 10's.
No, Offday CR 10 Tablet 10's is not a contraceptive on its own.
No, Offday CR 10 Tablet 10's is unlikely to cause weight loss.
The recommended dosage can vary greatly depending on the reason for taking the medication. It's crucial to follow your doctor's instructions precisely. Taking an incorrect dosage can lead to ineffective treatment or adverse side effects.
No, Offday CR 10 Tablet 10's does not cause miscarriages. However, it is not safe to take Offday CR 10 Tablet 10's during pregnancy.
Offday CR 10 Tablet 10's can generally be taken either before or after a meal. There is no strict requirement regarding the timing of food intake.
Offday CR 10 Tablet 10's contains Norethisterone, a second-generation progestin.
The duration of Offday CR 10 Tablet 10's use can vary depending on the specific medical condition being treated.
Yes, Offday CR 10 Tablet 10's treats irregular menstrual cycles.
Even after taking Offday CR 10 Tablet 10's and having unprotected sex, one can get pregnant. However, Offday CR 10 Tablet 10's is a category X pregnancy drug. It is not recommended for use during pregnancy as it may harm the unborn baby. Please consult a doctor if you are pregnant or planning for pregnancy.
Common side effects of Offday CR 10 Tablet 10's may cause unusual vaginal bleeding or spotting, dizziness, dry mouth, constipation, nausea, diarrhoea, headache, breast pain, and tenderness. Most of these side effects of Offday CR 10 Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Yes, Offday CR 10 Tablet 10's can lead to weight gain in some persons. However, it's crucial to remember that this isn't a common adverse effect. The potential risk of weight gain varies based on the individual and the dosage. Talk to your doctor or pharmacist if you are concerned about weight gain or have any other questions regarding norethisterone acetate. They can provide personalized information based on your circumstances.
Limited research is available. Seek medical attention from your doctor if you have any questions. Remember that self-medication can be risky. Always consult with a healthcare professional for proper diagnosis and treatment.
Yes, bleeding may occasionally occur while taking Offday CR 10 Tablet 10's. If you're experiencing bleeding while on Offday CR 10 Tablet 10's and you're concerned, it's important to consult with your healthcare provider. They can determine if the bleeding is normal or if there's another underlying issue.
Offday CR 10 Tablet 10's usually stops irregular bleeding within a few days, but this varies from person to person. If bleeding persists or worsens, consult your doctor.
The duration of Offday CR 10 Tablet 10's use depends on your specific medical condition and the reason for taking it.
The exact dosage and schedule for Offday CR 10 Tablet 10's will vary based on your individual health needs. It is important to follow your doctor's instructions to ensure effective treatment and minimize side effects.
If you forget a dose of Offday CR 10 Tablet 10's, take it as soon as possible. If it's been more than 12 hours, skip the missed dose and continue with your regular schedule or as directed by the physician.
Yes, Offday CR 10 Tablet 10's can interact with other medications. It's important to avoid taking Offday CR 10 Tablet 10's with any medications without consulting your doctor first. They can assess the potential risks and benefits and recommend alternative treatments if necessary.
Store in a cool and dry place away from sunlight. Keep Offday CR 10 Tablet 10's out of reach and out of sight to children.
Offday CR 10 Tablet 10's can be used to treat long-term disorders like endometriosis. But you should talk to your doctor about the long-term advantages and risks.
There is no direct drug interaction between alcohol and Offday CR 10 Tablet 10's. However, heavy alcohol consumption can stress your liver and worsen side effects like headache or nausea. It is best to limit alcohol intake while taking this medicine. Talk to your doctor for further guidance.
This medicine is generally not recommended for breastfeeding mothers, as small amounts of the hormone can pass into breast milk and may affect milk production. Always consult your doctor or pharmacist to discuss safer alternatives.
Yes, it is generally safe to take common over-the-counter painkillers like ibuprofen or paracetamol alongside Offday CR 10 Tablet 10's to manage menstrual cramps or headaches. However, it is always a good practice to talk to your doctor or pharmacist before combining any medications.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Unit 3A, Level 2, The Centrium Phoenix Market City Complex, Lbs Road, Kurla West Mumbai Mumbai City Mh 400070 In
Other Info - OFF0056
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