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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Olmibid Trio-40 Tablet is used for lowering high blood pressure (hypertension) by removing extra fluid (electrolytes) from the body. It works by relaxing and widening the narrowed blood vessels. It reduces the heart's workload and makes it more efficient at pumping blood throughout the body. Also, it removes extra water/fluid and certain electrolyte overload from the body. Thus, it lowers fluid overload and high blood pressure, improves blood flow, and reduces the future risk of a heart attack and stroke. In some cases, it may cause common side effects such as nausea, upset stomach, dehydration, headache, diarrhoea, electrolyte imbalance, headache, feeling exhausted, swollen ankles, dizziness, and decreased blood pressure. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer :

Avaxa Pharmaceuticals

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Olmibid Trio-40 Tablet

Olmibid Trio-40 Tablet belongs to a group of medications called 'anti-hypertensives' primarily used for lowering high blood pressure (hypertension) by removing extra fluid (electrolytes) from the body. High blood pressure is a chronic condition in which the blood's force against the artery wall is high. As a result, it increases the risk of heart-related diseases like heart attack, heart failure, stroke, irregular heartbeat, and other complications.

Olmibid Trio-40 Tablet is a combination of three medicines: Olmesartan medoximil, Amlodipine, and Hydrochlorothiazide. Olmesartan medoximil is a prodrug and breaks down into active form, i.e., olmesartan once absorbed in the GIT (Gastrointestinal tract). An angiotensin receptor blocker (ARB) blocks the hormone angiotensin, thereby relaxing and widening the narrowed blood vessels. Amlodipine is a calcium channel blocker; it reduces the heart's workload and makes it more efficient at pumping blood throughout the body. Hydrochlorothiazide is a diuretic or water pill that removes extra water/fluid and certain electrolyte overload from the body. Together, Olmibid Trio-40 Tablet lowers fluid overload, raises blood pressure, improves blood flow, and reduces the future risk of a heart attack and stroke.

Depending upon your medical condition, you are advised to take Olmibid Trio-40 Tablet for as long as your doctor has prescribed it for you. The most common side effects of Olmibid Trio-40 Tablet are nausea, upset stomach, dehydration, headache, diarrhoea, electrolyte imbalance, headache, feeling exhausted, swollen ankles, dizziness, and decreased blood pressure in some cases. Most of these side effects of Olmibid Trio-40 Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Do not use potassium supplements or salt substitutes unless your doctor tells you. In rare cases, Olmibid Trio-40 Tablet can cause a condition that results in a skeletal muscle problem, leading to further kidney failure. If you notice unexplained muscle pain, dark-coloured urine, tenderness, or weakness, especially if you also have a fever or unexplained tiredness, immediately contact the doctor. Try not to stop taking this medicine of your own. Let your doctor know about this, as it may cause a rise in blood pressure and increase heart disease and stroke risk. Inform your doctor if you are suffering from kidney, liver, heart disease, or diabetes. If you are pregnant or breastfeeding, do not take Olmibid Trio-40 Tablet as it is a category D pregnancy drug and may harm the baby. Do not use the Olmibid Trio-40 Tablet if you cannot urinate, are dehydrated, have low blood pressure (hypotension), or have had cardiogenic shock (sudden stopping blood flow to the heart). Please tell your doctor if you are taking any other medicines or are allergic to this medicine. Reducing table salt (sodium chloride) in your food often helps lower blood pressure.

Uses of Olmibid Trio-40 Tablet

Treatment of Hypertension (high blood pressure)

Directions for Use

Swallow the medicine as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Olmibid Trio-40 Tablet belongs to a group of medications called 'anti-hypertensives' primarily used for lowering high blood pressure (hypertension) by removing extra fluid (electrolytes) from the body. Olmibid Trio-40 Tablet is a combination of three medicines: Olmesartan medoximil, Amlodipine, and Hydrochlorothiazide. Olmesartan medoximil is a prodrug and breaks down into active form, i.e., olmesartan once absorbed in the GIT (Gastrointestinal tract). An angiotensin receptor blocker (ARB) blocks the hormone angiotensin, thereby relaxing and widening the narrowed blood vessels. Amlodipine is a calcium channel blocker; it reduces the heart's workload and makes it more efficient at pumping blood throughout the body. Hydrochlorothiazide is a diuretic or water pill that removes extra water/fluid and certain electrolyte overload from the body. Together, Olmibid Trio-40 Tablet lowers fluid overload, raises blood pressure, improves blood flow, and reduces the future risk of a heart attack and stroke.

How Olmibid Trio-40 Tablet Works

Olmibid Trio-40 Tablet is a combination of three medicines: Olmesartan medoximil, Amlodipine, and Hydrochlorothiazide. Olmesartan medoximil is a prodrug and breaks down into active form, i.e., olmesartan once absorbed in the GIT (Gastrointestinal tract). An angiotensin receptor blocker (ARB) blocks the hormone angiotensin, thereby relaxing and widening the narrowed blood vessels. Amlodipine is a calcium channel blocker; it reduces the heart's workload and makes it more efficient at pumping blood throughout the body. Hydrochlorothiazide is a diuretic or water pill that removes extra water/fluid and certain electrolyte overload from the body. Together, Olmibid Trio-40 Tablet lowers fluid overload, raises blood pressure, improves blood flow, and reduces the future risk of a heart attack and stroke.<

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Olmibid Trio-40 Tablet

Do not take more than the prescribed dose of Olmibid Trio-40 Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not use Olmibid Trio-40 Tablet if you are pregnant, planning for pregnancy, or unable to urinate (anuria). If you have diabetes and taking Olmibid Trio-40 Tablet with other blood pressure-lowering pills like 'aliskiren,' immediately stop taking both together and consult a doctor. Besides this, it is contraindicated in low blood pressure (hypotension), cardiogenic shock (sudden stopping of blood flow to the heart), and aortic stenosis (heart valve problem). Olmibid Trio-40 Tablet may pass into breast milk, so before starting Olmibid Trio-40 Tablet , either you need to stop nursing or you should not take Olmibid Trio-40 Tablet while breastfeeding. Please inform your doctor before surgery if you are taking Olmibid Trio-40 Tablet as it needs to be stopped because it might lower the blood pressure further if taken along with local anaesthesia. Avoid potassium salt or its substitute intake while using Olmibid Trio-40 Tablet to avoid any electrolyte imbalance. Olmibid Trio-40 Tablet can pass into breast milk, but its effect on the baby is unknown. So, it is better to tell your doctor if you take Olmibid Trio-40 Tablet and breastfeeding.

Drug-Drug Interactions

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AmlodipineDantrolene
Critical

Drug-Drug Interactions

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How does the drug interact with Olmibid Trio-40 Tablet:
Using aliskiren together with olmesartan may increase the risk of serious side effects (kidney problems, low blood pressure, and high potassium levels in the blood).

How to manage the interaction:
Taking Olmibid Trio-40 Tablet with Aliskiren is not recommended as it can cause an interaction, they can be taken if advised by a doctor. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat.It is crucial that you continue to consume enough fluids while taking these medications. Do not stop using any medications without consulting a doctor.
AmlodipineDantrolene
Critical
How does the drug interact with Olmibid Trio-40 Tablet:
Using Olmibid Trio-40 Tablet together with dantrolene may increase the risk of hyperkalemia (high blood potassium).

How to manage the interaction:
Taking Olmibid Trio-40 Tablet with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
Critical
How does the drug interact with Olmibid Trio-40 Tablet:
Taking Dofetilide and Olmibid Trio-40 Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Combining Dofetilide and Olmibid Trio-40 Tablet together is not recommended as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Olmibid Trio-40 Tablet:
Taking Cisapride and Olmibid Trio-40 Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Combining Cisapride and Olmibid Trio-40 Tablet together is generally avoided as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, or fast or pounding heartbeats, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Olmibid Trio-40 Tablet:
Taking Olmibid Trio-40 Tablet with triamterene may increase potassium levels in the blood. (High potassium levels can cause hyperkalemia, which can lead to kidney failure, muscular paralysis, abnormal heart rhythm, and cardiac arrest in extreme cases).

How to manage the interaction:
Although taking Olmibid Trio-40 Tablet with triamterene may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Olmibid Trio-40 Tablet:
When Olmibid Trio-40 Tablet is taken with captopril, it may cause low blood pressure, kidney problems, and may increase potassium levels in the blood.

How to manage the interaction:
Although taking Olmibid Trio-40 Tablet with captopril may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
Olmesartan medoxomilPotassium citrate
Severe
How does the drug interact with Olmibid Trio-40 Tablet:
Coadministration of Olmibid Trio-40 Tablet may increase potassium levels in the blood, which can lead to kidney failure, muscular paralysis, and abnormal heart rhythm.

How to manage the interaction:
Although taking Olmibid Trio-40 Tablet together with potassium citrate may result in an interaction, they can be taken together if prescribed by your doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Olmibid Trio-40 Tablet:
Coadministration of Olmibid Trio-40 Tablet with enalapril can elevate the risk of adverse effects such as low blood pressure, kidney impairment, and hyperkalemia (high blood potassium). Hyperkalemia can cause kidney failure, strong paralysis, abnormal heart rhythm, and cardiac arrest in extreme instances. If you are elderly, dehydrated, or have renal disease, diabetes, or severe heart failure, you are more prone to develop hyperkalemia while taking these medications.

How to manage the interaction:
Although taking Olmibid Trio-40 Tablet together with enalapril may result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience signs and symptoms of hyperkalemia, such as nausea, vomiting, confusion, numbness, tingling in hands and feet, and irregular heartbeat. It is advised to limit the intake of potassium-rich foods like tomatoes, bananas, mangoes, beans, and potassium-containing supplements. Do not discontinue any medication without consulting your doctor.
How does the drug interact with Olmibid Trio-40 Tablet:
Taking Amiloride with Olmibid Trio-40 Tablet can elevate potassium levels in the blood. (High potassium levels can cause hyperkalemia, which can lead to kidney failure, muscular paralysis, abnormal heart rhythm, and cardiac arrest in extreme cases).

How to manage the interaction:
Although taking amiloride with Olmibid Trio-40 Tablet may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop using any medications without talking to a doctor.
How does the drug interact with Olmibid Trio-40 Tablet:
Taking ramipril together with olmesartan may increase the risk of side effects (blood pressure, kidney function impairment, and a condition called Hyperkalemia - high blood potassium).

How to manage the interaction:
Although taking Olmibid Trio-40 Tablet with ramipril may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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AMLODIPINE-5MG+HYDROCHLOROTHIAZIDE-12.5MG+OLMESARTAN MEDOXOMIL-40MGPotassium rich foods
Moderate

Drug-Food Interactions

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AMLODIPINE-5MG+HYDROCHLOROTHIAZIDE-12.5MG+OLMESARTAN MEDOXOMIL-40MGPotassium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt

How to manage the interaction:
Taking Olmibid Trio-40 Tablet with potassium-containing salt substitutes or potassium supplements can cause high levels of potassium in the blood. Avoid taking potassium-containing salt substitutes or potassium supplements while being treated with Olmibid Trio-40 Tablet.

Diet & Lifestyle Advise

  • Create a well-balanced and healthy diet that includes vegetables, fruits, whole grains, legumes, omega-3-rich foods, and lean protein sources.

  • Keep your weight under control with a BMI of 19.5-24.9.

  • Avoid chronic stress, as it can raise your blood pressure.

  • Spend time with your loved ones to cope with stress and practice mindfulness techniques.

  • Be mindful of salt; consume no more than 2,300 mg each day.

  • Limit or avoid alcohol consumption.

  • Quitting smoking is the best strategy to lower the risk of heart disease.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES
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Alcohol

Unsafe

You are recommended not to consume alcohol and Olmibid Trio-40 Tablet to avoid unpleasant side effects like drowsiness, dizziness, and liver damage.

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Pregnancy

Unsafe

Olmibid Trio-40 Tablet is not recommended during pregnancy as it contains Olmesartan, which is a category D pregnancy drug. This medicine may cause fetal damage and can affect the unborn baby (fetus).

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Breast Feeding

Unsafe

Olmibid Trio-40 Tablet is known to pass breast milk, but its effect on the baby is unknown. So, before breastfeeding, let your doctor know about this. Either you need to stop breastfeeding for using Olmibid Trio-40 Tablet or stop taking Olmibid Trio-40 Tablet .

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Driving

Caution

Drive with caution; Olmibid Trio-40 Tablet usually causes drowsiness and affects driving ability.

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Liver

Caution

Olmibid Trio-40 Tablet to be taken with caution, especially if you have or have had a history of liver disease. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.

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Kidney

Caution

Olmibid Trio-40 Tablet to be taken with caution, especially if you have had a history of kidney disease. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.

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Children

Caution

Efficacy and safety of Olmibid Trio-40 Tablet have not been established in children. If prescribed, it should be strictly under medical supervision and only if the benefits outweigh the harm.

Have a query?

FAQs

Olmibid Trio-40 Tablet is used for lowering high blood pressure (hypertension) by removing extra fluid (electrolytes) from the body.

Olmibid Trio-40 Tablet is a combination of three medicines: Olmesartan medoximil, Amlodipine, and Hydrochlorothiazide. Olmesartan medoximil relaxes and widens the narrowed blood vessels. Amlodipine reduces the heart&amp;#039;s workload and makes the heart more efficient at pumping blood throughout the body. Hydrochlorothiazide is a diuretic or water pill that removes extra water/fluid and certain electrolyte overload from the body. Together, Olmibid Trio-40 Tablet lowers fluid overload, raises blood pressure, improves blood flow, and reduces the future risk of a heart attack and stroke.

Olmibid Trio-40 Tablet can be safely taken as long as your doctor prescribes it. Conditions such as high blood pressure are life-long conditions, and one should not abruptly discontinue it without discussing it with a doctor. Discontinuing Olmibid Trio-40 Tablet may lead to increased blood pressure and a high risk of heart attack and stroke.

It&amp;#039;s unlikely that Olmibid Trio-40 Tablet affects fertility in men or women. However, in some cases, some water pills like hydrochlorothiazide may lead to erectile dysfunction. For the best advice, please consult your doctor.

Please inform your doctor before surgery if you are taking Olmibid Trio-40 Tablet as it needs to be stopped because it might lower the blood pressure further if taken along with local anaesthesia.

Do not use Olmibid Trio-40 Tablet if you are pregnant, planning for pregnancy, or unable to urinate. If you have diabetes and taking Olmibid Trio-40 Tablet with other blood pressure-lowering pills like &amp;#039;aliskiren&amp;#039;, immediately stop taking both together and consult a doctor.

High blood pressure during pregnancy is called &amp;#039;Pregnancy-induced hypertension (PIH). It is harmful to both the baby and the mother. In the mother, very high blood pressure can cause seizures (fits), headache, swelling of feet, kidney damage, and a higher risk of bleeding during pregnancy and delivery. This can also affect the baby by causing abnormal fetal heart rate, risk of stillbirth, and a small baby. So, during pregnancy, you should have regular blood pressure monitoring. Visit your Obstetrician if you have any concerns about blood pressure during pregnancy.

Yes, Olmibid Trio-40 Tablet is known to cause ankle swelling (oedema) upon long-term use as Olmibid Trio-40 Tablet amlodipine. Please try to keep your feet up when sitting for long hours. If the problem persists still, consult your doctor and do as advised.

Olmibid Trio-40 Tablet can be taken with or without food or as advised by the doctor.

You are not recommended to stop Olmibid Trio-40 Tablet , as stopping it may raise blood pressure and increase the risk of heart disease and stroke. Therefore, inform your doctor if you intend to stop taking Olmibid Trio-40 Tablet or if you experience any difficulty while taking Olmibid Trio-40 Tablet .

To control high blood pressure, it’s important to follow a balanced diet that includes proteins, whole grains, and fiber-rich fruits and vegetables. Limit your intake of carbohydrates, salt, and sugar. Before making any changes to your diet or eating habits, consult your doctor. Regular exercise and weight loss are also recommended. Avoid smoking and drinking.

You may observe a decrease in your blood pressure within 2 weeks of starting Olmibid Trio-40 Tablet . But to notice the full effects of Olmibid Trio-40 Tablet , it may take up to 8 weeks.

You are recommended to take the first dose before bedtime, as Olmibid Trio-40 Tablet can cause dizziness. After the first dose, you can take Olmibid Trio-40 Tablet at any time of day, but it’s essential to take it at the same time each day for consistency and to help you remember.

You may feel dizzy after taking Olmibid Trio-40 Tablet as it is one of its side effects. Avoid driving if you feel dizzy. This condition doesn’t require any medical treatment as it will gradually reduce over time. Consult your doctor, if the condition persists longer.

Olmibid Trio-40 Tablet does not usually cause weight gain. Change your lifestyle and maintain a balanced diet if you observe any changes in your weight. However, in rare cases, chronic diarrhoea with weight loss may occur. If the patient experiences diarrhoea while taking Olmibid Trio-40 Tablet and the cause is unknown, consult a doctor.

Olmibid Trio-40 Tablet includes side effects such as painful joints, fast heartbeat, skin rash or itchiness, chest tightness, shortness of breath, weak muscles, swelling of feet, hands, or ankles. Please, consult your doctor if you experience any of these side effects.

Take the Olmibid Trio-40 Tablet whole with a glass of water; do not crush or chew it. To help you remember, try to take it at the same time every day.

Before taking Olmibid Trio-40 Tablet , inform your doctor if you have kidney, liver or heart disease, diabetes, or asthma. Also, let your doctor know about all the medications you might be taking.

You are recommended to be cautious while driving or operating machinery after taking Olmibid Trio-40 Tablet as it may cause drowsiness which affects the driving ability.

Inform your doctor about all the medications you are currently taking, as Olmibid Trio-40 Tablet may interact with other drugs, potentially causing harmful reactions. It may interact with medications such as antidepressants (lithium), heart rhythm drugs (digoxin), blood thinners (aspirin), antidiabetics (metformin, insulin), erectile dysfunction treatments (sildenafil), cholesterol-lowering drugs (simvastatin), immune-suppressants (cyclosporine), other anti-hypertensives (atenolol), pain relievers (ibuprofen), and ulcer medications (carbenoxolone).

Country of origin

India
Other Info - OLM0389

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