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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Ondem Sachet 4 gm is used in the prevention of vomiting and nausea that usually occur after cancer chemotherapy, radiation treatment, or surgery. It contains Ondanestron, which works by blocking the action of a chemical in the body (serotonin) responsible for causing nausea and vomiting. It may cause common side effects such as constipation, headache, diarrhea, drowsiness, flushing (a feeling of warmth), weakness, and tiredness. Before taking this medication, inform your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and any pre-existing medical conditions.

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Whats That

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Composition :

ONDANSETRON-4MG

Manufacturer/Marketer :

Alkem Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Ondem Sachet 4 gm

Ondem Sachet 4 gm belongs to a group of medications called ' antiemetics,' primarily used in the prevention of vomiting (being sick) and nausea (feeling sick) that usually occur after cancer chemotherapy, radiation treatment, or surgery. Nausea is an uneasy feeling in which a person feels an urge to vomit, while vomiting is the natural response of the body to expel the stomach contents from the mouth forcefully.

Ondem Sachet 4 gm contains Ondanestron, which works by blocking the action of a chemical in the body (serotonin) responsible for causing nausea and vomiting. As a result, Ondem Sachet 4 gm prevents the sensation of nausea and vomiting caused by conditions like surgery, cancer chemotherapy, pregnancy, or motion sickness.

Take Ondem Sachet 4 gm exactly as prescribed. Your doctor will advise you on how often you take Ondem Sachet 4 gm based on your medical condition. You may experience common side effects such as constipation, headache, diarrhea, drowsiness, flushing (a feeling of warmth), weakness, and tiredness. However, not every person experiences these side effects, and some of the unpleasant effects of Ondem Sachet 4 gm do not require medical attention. If the side effects persist or worsen, please consult your doctor.

Before using Ondem Sachet 4 gm, inform your doctor if you are allergic to any of its ingredients. Do not use Ondem Sachet 4 gm if you are taking apomorphine (a medicine used to treat Parkinson's disease), as it may cause a sharp drop in blood pressure and even fainting. Inform your doctor before using Ondem Sachet 4 gm if you have any medical conditions, such as severe constipation, bowel obstruction, depression, electrolyte imbalance, irregular heartbeat, liver problems, or a history of tonsils or adenoid removal surgery. Ondem Sachet 4 gm should be used during pregnancy and breastfeeding only if prescribed by a doctor.

Uses of Ondem Sachet 4 gm

Ondem Sachet 4 gm is used in the prevention of Nausea and Vomiting. The detailed uses of Ondem Sachet 4 gm are as follows:<br/> • Chemotherapy-Induced Nausea and Vomiting: Ondem Sachet 4 gm is frequently prescribed to alleviate nausea and vomiting caused by chemotherapy treatments.<br/> • Radiation Therapy Support: Ondem Sachet 4 gm can help manage nausea and vomiting experienced by patients undergoing radiation therapy, improving treatment tolerance.<br/> • Postoperative Nausea and Vomiting Relief: Many patients experience nausea or vomiting after surgical procedures, and Ondem Sachet 4 gm is effective in controlling and reducing these symptoms.<br/>

Directions for Use

  • Ondem Sachet 4 gm can be taken with or without food, as advised by the doctor.
  • Typically, it is taken twice daily. However, follow your doctor's instructions on the dosage and timing of this medication. 
  • Swallow the tablet as a whole with a glass of water.
  • Do not crush, chew, break, or open it.

Medicinal Benefits

Ondem Sachet 4 gm is an anti-emetic medication primarily used to prevent and treat nausea and vomiting associated with conditions such as cancer chemotherapy, radiation treatment, and surgery. When serotonin levels increase in the blood, it stimulates the CTZ receptor (chemoreceptor trigger zone) located in the brain responsible for controlling nausea and vomiting. Ondem Sachet 4 gm contains Ondansetron, which works by inhibiting the release of serotonin, thereby preventing nausea and vomiting.

How Ondem Sachet 4 gm Works

Ondem Sachet 4 gm contains Ondanestron, which works by blocking the action of a chemical in the body (serotonin) responsible for causing nausea and vomiting. As a result, Ondem Sachet 4 gm prevents the sensation of nausea and vomiting caused by conditions like surgery, cancer chemotherapy, pregnancy, or motion sickness.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Ondem Sachet 4 gm

Do not take more than the prescribed dose of Ondem Sachet 4 gm, as it may lead to an overdose. Symptoms of an overdose may include sudden loss of vision for a short time, irregular heartbeat, constipation, fainting, dizziness, or light-headedness. If you suspect that you have taken an overdose of this medication or notice any unusual symptoms, please consult a doctor immediately.

Drug Warnings

Do not use Ondem Sachet 4 gm if you are allergic to any of its ingredients. Avoid using Ondem Sachet 4 gm if you are taking apomorphine (a medicine used to treat Parkinson's disease), as it may cause a sharp drop in blood pressure and even fainting. Inform your doctor before using Ondem Sachet 4 gm if you have any medical conditions, such as severe constipation, bowel obstruction, depression, electrolyte imbalance, heart or blood vessel problems (such as irregular heartbeats and high blood pressure), diabetes, liver problems, or a history of tonsils or adenoid removal surgery. Tell your doctor if you are taking any medications for depression, as using them alongside Ondem Sachet 4 gm may increase the risk of serotonin syndrome, a potentially life-threatening condition. Ondem Sachet 4 gm is not recommended for use during early pregnancy (first trimester), as it may increase the risk of birth defects in the mouth and face of the baby. Avoid breastfeeding while taking Ondem Sachet 4 gm, as small amounts of the medicine may pass into breast milk. Avoid consuming alcohol while taking Ondem Sachet 4 gm, as it may worsen the side effects like drowsiness.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Ondem Sachet 4 gm:
Taking Ondem Sachet 4 gm with Ziprasidone can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Ondem Sachet 4 gm with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Ondem Sachet 4 gm:
Taking Ondem Sachet 4 gm with crizotinib increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Although taking Ondem Sachet 4 gm along with crizotinib can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Ondem Sachet 4 gm:
Using Nortriptyline together with Ondem Sachet 4 gm can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Co-administration of Ondem Sachet 4 gm along with nortriptyline can result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, a shaking sensation, incoordination, stomach cramp, nausea, vomiting, or diarrhea. while taking these medications. Do not discontinue any medications without a doctor's advice.
OndansetronVandetanib
Severe
How does the drug interact with Ondem Sachet 4 gm:
Taking Ondem Sachet 4 gm with vandetanib increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Although taking Ondem Sachet 4 gm along with vandetanib can result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Ondem Sachet 4 gm:
Taking Ondem Sachet 4 gm with hydroxychloroquine increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Co-administration of Ondem Sachet 4 gm along with hydroxychloroquine can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Ondem Sachet 4 gm:
Taking Ondem Sachet 4 gm with disopyramide increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Although taking Ondem Sachet 4 gm along with disopyramide can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
OndansetronVemurafenib
Severe
How does the drug interact with Ondem Sachet 4 gm:
Although it is a very rare adverse effect, taking Ondem Sachet 4 gm with vemurafenib increases the risk of an abnormal heart rhythm. If you're dealing with other heart illnesses or electrolyte imbalances (for example, magnesium or potassium loss likely due to serious or prolonged diarrhoea or vomiting), you may be at greater risk.

How to manage the interaction:
Although taking Ondem Sachet 4 gm along with vemurafenib can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without a doctor's advice
How does the drug interact with Ondem Sachet 4 gm:
Taking Ondem Sachet 4 gm with escitalopram may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Co-administration of Ondem Sachet 4 gm along with escitalopram can possibly result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucinations (seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Ondem Sachet 4 gm:
When Ondem Sachet 4 gm is taken with paroxetine, can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Co-administration of Ondem Sachet 4 gm along with paroxetine can result in an interaction, it can be taken if a doctor has advised it. However, if you have sudden dizziness, lightheadedness, fainting, confusion, hallucination, fits, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles, or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea, or fast or rapid heartbeats during therapy, consult the doctor. Do not stop using any medication without consulting a doctor.
How does the drug interact with Ondem Sachet 4 gm:
Taking Ondem Sachet 4 gm and Sotalol can increase the risk or severity of irregular heart rhythms which can be severe.

How to manage the interaction:
Although taking Ondem Sachet 4 gm and Sotalol can result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat consult a doctor. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat small meals throughout the day and eat slowly to help digestion.
  • If you are sensitive to food smells, try eating cold or room-temperature foods instead of hot ones.
  • Avoid acidic foods or drinks like orange or grapefruit juice.
  • After your meals, rest with your head elevated about 12 inches above your head.
  • Drink liquids or water between meals rather than during meals.
  • Eat when you are least nauseated to help prevent discomfort.
  • Avoid consuming greasy or oily foods, as these foods can trigger nausea and vomiting.
  • Include clear broths, non-fat yoghurt, fruit juice, sherbet, and sports drinks for fluid makeup that has been lost due to vomiting.

Habit Forming

No

Therapeutic Class

ANTIEMETICS
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Alcohol

Caution

Alcohol has no known direct interaction with Ondem Sachet 4 gm. However, it is advisable to avoid consuming alcohol while taking Ondem Sachet 4 gm, as it may worsen the side effects like drowsiness.

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Pregnancy

Caution

Ondem Sachet 4 gm should be used during pregnancy only if prescribed by a doctor. It is generally not recommended for use during early pregnancy (first trimester), as it may increase the risk of birth defects in the mouth and face of the baby.

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Breast Feeding

Caution

Avoid breastfeeding while taking Ondem Sachet 4 gm, as small amounts of the medicine may pass into breast milk.

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Driving

Caution

Ondem Sachet 4 gm does not affect your ability to drive. However, if you experience drowsiness or blurred vision after taking Ondem Sachet 4 gm, avoid driving or operating any heavy machinery.

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Liver

Caution

In individuals with liver problems, the use of Ondem Sachet 4 gm is allowed if prescribed by a doctor. However, patients with severe liver impairment should take a low dose of Ondem Sachet 4 gm as much as possible. Do not take more than 8 mg of Ondem Sachet 4 gm per day in case of liver disease.

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Kidney

Safe if prescribed

The use of Ondem Sachet 4 gm is considered safe in patients with kidney disorders. No dose adjustment is required.

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Children

Safe if prescribed

Ondem Sachet 4 gm should not be given to children below 4 years of age, as its safety and effectiveness have not been established in this age group. The use of Ondem Sachet 4 gm is safe in children above 4 years of age if prescribed by a doctor.

Have a query?

FAQs

Ondem Sachet 4 gm is used in the prevention of vomiting and nausea that usually occur after cancer chemotherapy, radiation treatment, or surgery.

Ondem Sachet 4 gm contains Ondanestron, which works by blocking the action of a chemical in the body (serotonin) responsible for causing nausea and vomiting.

Ondem Sachet 4 gm may cause drowsiness and changes in vision, so avoid driving or operating any machines that require mental alertness.

People with an irregular heartbeat (arrhythmia), and phenylketonuria (too much of the protein phenylalanine in the blood) should not take Ondem Sachet 4 gm as it may cause serious conditions. The liver patient should not take more than 8 mg of Ondem Sachet 4 gm daily. Taking Ondem Sachet 4 gm with apomorphine can cause a sharp dip in blood pressure, even leading to death, so avoid its intake together.

Ondem Sachet 4 gm contains Ondansetron, an antiemetic drug, used in the prevention of vomiting and nausea.

Ondem Sachet 4 gm is ineffective in preventing nausea associated with motion sickness.

Before taking Ondem Sachet 4 gm, inform your doctor about all your medical conditions, sensitivities, and medications you are using. Also, tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Ondem Sachet 4 gm usually works quickly, usually within 30 minutes, but it can take up to two hours for the full effect.

Common side effects of Ondem Sachet 4 gm may include constipation, headache, diarrhea, drowsiness, flushing (a feeling of warmth), weakness, and tiredness. However, not every person experiences these side effects, and some of the unpleasant effects of Ondem Sachet 4 gm do not require medical attention. If the side effects persist or worsen, please consult your doctor.

Ondem Sachet 4 gm was not found to be beneficial in the treatment of seasickness.

Ondem Sachet 4 gm works by blocking the action of a chemical in the body (serotonin) that is responsible for causing nausea and vomiting. As a result, Ondem Sachet 4 gm prevents the sensation of nausea and vomiting caused by conditions like surgery, cancer chemotherapy, pregnancy, or motion sickness.

Yes, you can take Ondem Sachet 4 gm half an hour to 1 hour before meals.

If you forget to take a dose of Ondem Sachet 4 gm, take it as soon as you remember. However, if it is time for your next dose, skip the missed dose and take your regular dose. Never take a double dose to make up for a forgotten dose.

If you take more than the recommended dose of Ondem Sachet 4 gm, it may result in an overdose. Signs and symptoms of an overdose of Ondem Sachet 4 gm may include constipation, dizziness or lightheadedness, fainting, irregular heartbeat, and sudden loss of vision for a short time. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

No, Ondem Sachet 4 gm is not a steroid. Ondem Sachet 4 gm belongs to a class of drugs known as antiemetics.

While specific dosing instructions will vary depending on your individual needs and medical history. Always follow your doctor's prescribed dosage and timing for taking these medications.

Take Ondem Sachet 4 gm exactly as prescribed by the doctor. Take it at the same time daily, as it will help you to remember taking the medication.

Yes, Ondem Sachet 4 gm can be given during pregnancy if prescribed by a doctor. However, it is not recommended for use during early pregnancy (first trimester), as it may increase the risk of birth defects in the mouth and face of the baby.

Country of origin

INDIA

Manufacturer/Marketer address

Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Other Info - OND0088

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