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compositionComposition:THEOPHYLLINE-400MG
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Prescription Medicine
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Onimar 400 Tablet is used for the management of asthma and chronic obstructive pulmonary disease (COPD). It contains Theophylline, which works by relaxing the airway in the lungs and making it easier to breathe. In some cases, you may experience side effects such as nausea, vomiting, restlessness, tremors, headache, muscle cramps, and increased heart rate. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

THEOPHYLLINE-400MG

Manufacturer/Marketer :

Emcee Pharmaceuticals (P) Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Onimar 400 Tablet

Onimar 400 Tablet is a prescription medication used to prevent and treat wheezing, shortness of breath, and chest tightness caused by ongoing lung diseases like asthma and chronic obstructive pulmonary disease (COPD), which includes chronic bronchitis and emphysema. It belongs to a group of medicines called bronchodilators, which work by relaxing the muscles in your airways to make breathing easier. This medication is designed for long-term control and should not be used as a rescue treatment for sudden breathing emergencies.

For this medicine to work effectively, you must take it regularly at the same times every day, even when you feel well. Depending on the specific form your doctor prescribes, you may need to take it consistently either always with food or always on an empty stomach to ensure even absorption. Making positive lifestyle changes, such as avoiding respiratory irritants like secondhand smoke and dust, can further support your lung function and help improve your treatment results.

Some people may experience mild side effects like a mild headache, nausea, or trouble sleeping when first starting this medication. However, if you experience more serious symptoms such as a very rapid or irregular heartbeat, severe vomiting, tremors, or confusion, you should contact your doctor right away.

Do not take this if you are allergic to any of the ingredients in this medicine or to similar medications. Talk to your doctor before taking Onimar 400 Tablet if you have heart disease, thyroid problems, liver damage, kidney disease, or a history of stomach ulcers or seizures, as these conditions may require special monitoring or dose adjustments.

This medication can interact with other substances; for example, smoking tobacco or drinking alcohol can change how quickly your body clears the drug, making it less effective or increasing the risk of side effects. If you are pregnant, breastfeeding, or are an older adult, talk to your doctor or pharmacist to ensure this medicine is safe for your specific situation.

Uses of Onimar 400 Tablet

Onimar 400 Tablet is used to treat respiratory issues. The detailed uses of Onimar 400 Tablet are as follows: 

  • Asthma: Onimar 400 Tablet helps prevent sudden asthma attacks and long-term wheezing by keeping the airways in your lungs open and relaxed over time.
  • Chronic Bronchitis: It reduces chest tightness and shortness of breath by relaxing the inflamed airway muscles in individuals with chronic bronchitis.
  • Emphysema: It improves airflow and breathing capacity, helping you manage ongoing respiratory difficulties associated with damaged air sacs.
     

Key Benefits

Onimar 400 Tablet provides targeted relief that helps you return to your normal daily activities. It delivers several key benefits:

 

  • Easier Daily Breathing: By keeping the air passages in your lungs constantly relaxed, Onimar 400 Tablet helps reduce the daily struggle with shortness of breath, allowing you to perform routine activities with less fatigue.
  • Prevention of Nighttime Symptoms: Taking this medication consistently helps control overnight and early-morning wheezing, which can significantly improve your sleep quality.
  • Reduced Reliance on Rescue Inhalers: As a long-term controller medication, it helps lower the frequency and severity of sudden breathing flare-ups, meaning you may need to use your quick-relief rescue inhaler less often.
Side effects of Onimar 400 Tablet
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Maintain consistent habits, sleep patterns and food times to help maintain stability and reduce confusion.
  • Mindfulness techniques such as deep breathing or meditation help you stay focused and in the now.
  • Participate in cognitive therapy to enhance your ability to remember, focus and solve problems.
  • As directed by your physician, take your medications to help control underlying disorders like depression, anxiety or cognitive impairment.
Here are the steps to manage medication-triggered tremors or involuntary shaking:
  • Notify your doctor immediately if you experience tremors or involuntary shaking after taking medication or adjusting your medication regimen.
  • Your doctor may adjust your medication regimen or recommend alternative techniques like relaxation, meditation, or journaling to alleviate tremor symptoms.
  • Your doctor may direct you to practice stress-reducing techniques, such as deep breathing exercises, yoga, or journaling.
  • Regular physical activity, such as walking or jogging, can help reduce anxiety and alleviate tremor symptoms.
  • Your doctor may recommend lifestyle changes, such as avoiding caffeine, getting enough sleep, and staying hydrated, to help manage tremors.
  • Maintain regular follow-up appointments with your doctor to monitor tremor symptoms and adjust treatment plans as needed.

Directions for Use

Follow these step-by-step instructions for taking this medication:

  • Take this medication by mouth exactly as prescribed by your doctor.
  • If you are taking extended-release tablets or capsules, swallow them whole with a full glass of water. Do not crush, chew, or break them, as this can release the entire drug at once and increase the risk of side effects.
  • If you are using the liquid form, measure your dose carefully using a marked medical measuring spoon or device, rather than a household spoon, to ensure an accurate amount.
  • Always try to take your doses at the same time each day to keep a steady level of the medicine in your body.

Always follow your doctor's exact instructions regarding how and when to take your medication.
 

How Onimar 400 Tablet Works

Onimar 400 Tablet contains theophylline and works by targeting the smooth muscles that line the airways of your lungs. When you have respiratory conditions like asthma or COPD, these muscles can tighten and spasm, making the airways narrow and making it hard to breathe. This medication acts directly on these muscles, causing them to relax and widen the airways. Additionally, it helps decrease the lungs' sensitivity to allergens and other irritants that trigger inflammation and constriction. By keeping the air passages open and reducing muscle spasms, Onimar 400 Tablet ensures a steady, improved flow of oxygen in and out of your lungs.
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Alcohol

Caution

Alcohol can alter the way Onimar 400 Tablet works. Please consult your doctor if you intend to drink alcohol whilst taking Onimar 400 Tablet.

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Pregnancy

Consult your doctor

Please consult your doctor if you are pregnant before starting Onimar 400 Tablet.

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Breast Feeding

Consult your doctor

Please consult your doctor if you are breastfeeding before starting Onimar 400 Tablet.

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Driving

Caution

Onimar 400 Tablet usually causes dizziness, drowsiness and visual disturbances, which may affect their ability to drive or operate machinery. So, do not drive or operate heavy machinery if you feel sleepy or dizzy after taking Onimar 400 Tablet. Tell your doctor if you get these types of side effects.

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Liver

Caution

Onimar 400 Tablet to be taken with caution, especially if you have a history of liver disease. The dose may have to be adjusted by your doctor.

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Kidney

Safe if prescribed

Onimar 400 Tablet has no reported interactions; if you experience any difficulty, discuss it with your doctor.

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Children

Caution

Onimar 400 Tablet is not recommended for children under six years of age.

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Heart

Consult your doctor

Please consult your doctor before using Onimar 400 Tablet if you have pre-existing heart problems.

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Geriatrics

Caution

Onimar 400 Tablet can be taken by geriatric patients, but with caution and medical supervision.

What if I have taken an overdose of Onimar 400 Tablet

Do not take more than the prescribed dose of Onimar 400 Tablet as it may cause an overdose. The symptoms of overdose include slow heart rate, seizures (fits), fainting or weak pulse. Seizures caused due to overdose of Theophylline may cause permanent brain damage or it can be fatal. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Limit Caffeine Intake: Avoid consuming large amounts of coffee, tea, colas, energy drinks, or chocolate. Because Onimar 400 Tablet is chemically similar to caffeine, combining them can significantly increase your risk of experiencing side effects like a rapid heart rate, nervousness, and trouble sleeping.
  • Keep a Consistent Diet: Avoid making sudden, drastic changes to your daily diet (such as switching to a very high-protein or very high-carbohydrate diet) without discussing it with your doctor, as these dietary changes can alter how your body processes this medicine.
  • Avoid Smoking and Secondhand Smoke: Tobacco smoke speeds up how quickly your body clears this medication, which can lower its effectiveness. If you start or stop smoking while taking this medicine, you must inform your doctor, as your dose will need to be adjusted.
  • Stay Hydrated: Drinking plenty of water helps thin the mucus in your lungs, making it easier to cough up and clear your airways.
     

Have a query?

How Soon It Starts Working

The time required for Onimar 400 Tablet to start to work: The time required for Onimar 400 Tablet to show its action is unknown.

The time for which the effects of Onimar 400 Tablet last: The duration of action for Onimar 400 Tablet is unknown.

What if you forget to take Onimar 400 Tablet

If you miss a dose of Onimar 400 Tablet, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for the missed one.

Storage

Store this medication at room temperature, ideally between 20°C and 25°C (68°F to 77°F). Keep the container tightly closed and protect it from direct sunlight, excessive heat, and moisture (do not store it in the bathroom cabinet).

Drug Warnings

  • Get Regular Blood Tests: You must attend all scheduled appointments for blood tests. Your doctor needs to measure the exact amount of Onimar 400 Tablet in your blood to ensure it is at a safe and effective level.
  • Do Not Switch Brands Without Consultation: Different brands or formulations of this medicine can release the drug into your body at different rates. Never switch brands or switch between generic and brand-name versions without checking with your doctor first.
  • Monitor for Fever and Illness: If you develop a high fever or a severe viral illness (like the flu), contact your doctor. These conditions can slow down how your body processes the medicine, potentially leading to toxic levels in your blood.
  • Report Changes in Smoking Habits: Because smoking tobacco or marijuana significantly affects how your body processes this medicine, always inform your doctor immediately if you start, stop, or change your smoking habits.
     

Drug-Drug Interactions

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Drug-Drug Interactions

Inform your doctor if you are taking any of the following medicines, as they may interact.

  • Antibiotics (like ciprofloxacin or erythromycin): Can slow down how your body clears Onimar 400 Tablet, significantly increasing the risk of side effects and toxicity.
  • Seizure Medications (like phenytoin or carbamazepine): Can speed up the clearance of Onimar 400 Tablet, making it less effective in controlling your breathing symptoms.
  • Blood Pressure Medications (like beta-blockers): May block the airway-relaxing effects of this medicine, potentially causing severe breathing difficulties.

Drug-Food Interactions

  • Caffeine-Rich Foods and Drinks: Consuming coffee, tea, chocolate, or energy drinks can worsen side effects like shaking, headaches, and rapid heart rates.
  • High-Protein, Low-Carbohydrate Diets: May speed up the clearance of this drug, reducing its effectiveness, while high-carbohydrate, low-protein diets may do the opposite.

Drug-Disease Interactions

Inform your doctor if you have a history of the following conditions before taking Onimar 400 Tablet, as it may worsen your condition or cause complications.

  • Liver Damage: Severe liver disease can slow the processing of this drug, increasing the risk of toxic side effects in the body.
  • Heart Failure or Arrhythmias: This medicine can worsen irregular heart rhythms or increase strain on a weakened heart.
  • Seizure Disorders: May lower the seizure threshold, making seizures more likely to occur or harder to control.
  • Stomach Ulcers: This medication can stimulate stomach acid production, which may worsen active ulcers.
     

Drug-Drug Interactions

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How does the drug interact with Onimar 400 Tablet:
Co-administration of Onimar 400 Tablet with Riociguat can increase the risk of low blood pressure.

How to manage the interaction:
Taking Onimar 400 Tablet with Riociguat is not recommended but can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, lightheadedness, fainting, flushing (a sudden reddening of the face), headache, and nasal congestion (stuffy nose). Do not discontinue any medications without consulting a doctor.
How does the drug interact with Onimar 400 Tablet:
Taking esmolol with Onimar 400 Tablet, could make esmolol less effective and enhance the effects of Onimar 400 Tablet.

How to manage the interaction:
Although taking esmolol and Onimar 400 Tablet together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as nausea, vomiting, insomnia, shaking of hands and legs, restlessness, uneven heartbeats, or difficulty breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Onimar 400 Tablet:
Using propranolol together with Onimar 400 Tablet makes the propranolol less effective in controlling blood pressure, and it also increases the effects of Onimar 400 Tablet

How to manage the interaction:
Although taking Propranolol together with Onimar 400 Tablet can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, consult your doctor if you experience nausea, vomiting, sleeplessness, tremors, restlessness, irregular heartbeats, or difficulty breathing. Do not stop using any medication without consulting a doctor.
How does the drug interact with Onimar 400 Tablet:
Co-administration of Onimar 400 Tablet with mexiletine can increase the effect of mexiletine. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Onimar 400 Tablet with Mexiletine can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any symptoms such as nausea, vomiting, diarrhea, loss of appetite, headache, tremor, confusion, restlessness, insomnia, seizures, heart palpitations, and/or irregular heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Onimar 400 Tablet:
Taking Onimar 400 Tablet with ciprofloxacin may increase the blood levels of Onimar 400 Tablet, which increases the risk of side effects.

How to manage the interaction:
Although taking ciprofloxacin and Onimar 400 Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience nausea, vomiting, diarrhea, lack of appetite, headache, tremor(shaking of hands & legs), confusion, restlessness, sleeplessness, seizures(fits), irregular heartbeat, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Onimar 400 Tablet:
Combined use of Nebivolol with Onimar 400 Tablet may increase the effect of Onimar 400 Tablet.

How to manage the interaction:
Although there is a possible interaction between Onimar 400 Tablet and Nebivolol, you can take these medicines together if prescribed by your doctor. However, if you experience nausea, vomiting, insomnia, tremors, restlessness, irregular heartbeats, contact a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Onimar 400 Tablet:
Co-administration of tramadol with Onimar 400 Tablet can increase the effect of tramadol.

How to manage the interaction:
Taking Onimar 400 Tablet with tramadol together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any symptoms such as confusion, hallucination, seizure, increased heart rate, blurred vision, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Onimar 400 Tablet:
Co-administration of Bisoprolol with Onimar 400 Tablet may cause Bisoprolol to be less effective and increase the effects of Onimar 400 Tablet.

How to manage the interaction:
Although there may be an interaction, Bisoprolol can be taken with Onimar 400 Tablet if prescribed by the doctor. Consult the prescriber if you experience nausea, vomiting, insomnia, shaking hands and legs, restlessness, uneven heartbeats, or difficulty breathing. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Onimar 400 Tablet:
Taking fluvoxamine with Onimar 400 Tablet may significantly increase the blood levels of Onimar 400 Tablet.

How to manage the interaction:
Although taking fluvoxamine and Onimar 400 Tablet together can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as nausea, vomiting, diarrhea, loss of hunger, headache, shaking of hands and legs, confusion, restlessness, insomnia, fits, heart palpitations, or irregular heartbeat. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Onimar 400 Tablet:
Taking Metoprolol Succinate with Onimar 400 Tablet, could make Metoprolol Succinate less effective and enhance the effects of Onimar 400 Tablet.

How to manage the interaction:
Although taking metoprolol succinate and Onimar 400 Tablet together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as nausea, vomiting, insomnia, shaking of hands and legs, restlessness, uneven heartbeats, or difficulty breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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THEOPHYLLINE-400MGCaffeine containing foods/drinks
Moderate

Drug-Food Interactions

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THEOPHYLLINE-400MGCaffeine containing foods/drinks
Moderate
Common Foods to Avoid:
Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu

How to manage the interaction:
Caffeine consumption can modify Onimar 400 Tablet blood levels. Caffeine should be avoided in excess while using Onimar 400 Tablet. Consult a doctor if you suffer any symptoms such as headaches, sleeplessness, or increases in blood pressure or heart rate. Do not discontinue any medications without consulting a doctor.

All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIHYPONATREMIC]

FAQs

Onimar 400 Tablet is used to manage asthma and chronic obstructive pulmonary disease (COPD).

Onimar 400 Tablet contains Theophylline, which relaxes the lungs' airways and makes breathing easier.

Yes, Onimar 400 Tablet can lead to withdrawal symptoms. So, it should not be stopped abruptly. Consult your doctor, and your dose might be lowered if required.

No, dose of Onimar 400 Tablet should not be increased without consulting your doctor as it may increase the risk of hypokalemia (high blood potassium level), which may lead to side effects of Onimar 400 Tablet and also affect its efficacy.

Onimar 400 Tablet is contraindicated in patients who are allergic to any of its ingredients. It is advised to avoid taking Onimar 400 Tablet and beta-blockers like propranolol together at once.

If you are taking medication for seizures, it might worsen your condition and lead to symptoms like confusion, trouble talking, tremors or twitching, loss of muscle tone or tense muscles. Consult your doctor before taking Onimar 400 Tablet along with seizure medications.

No, you should not take Onimar 400 Tablet if you have ulcers, as it may worsen your ulcers and lead to bleeding and inflammation. So, please consult your doctor before starting Onimar 400 Tablet, as dose adjustment may be required.

Onimar 400 Tablet may cause side effects such as vomiting, diarrhoea, dizziness and indigestion. If these side effects persist or worsen, please consult your doctor.

Take Onimar 400 Tablet as advised by your doctor. Swallow it as a whole with a glass of water. Do not break, crush or chew it.

Onimar 400 Tablet starts working quickly, and you may see an improvement in symptoms within about 30 minutes of taking it. However, it may take a little longer, about 4 to 8 hours, to show the full effect. If there is no considerable improvement in your symptoms, consult your doctor.

While taking Onimar 400 Tablet, you should avoid foods high in caffeine, such as cocoa, tea, coffee, and chocolate, as these foods increase Onimar 400 Tablet side effects. Also, you should avoid alcohol and tobacco. If you have any concerns regarding food restriction, please discuss with your doctor.

It is best to avoid or strictly limit your intake of caffeine-rich beverages like coffee, tea, and energy drinks. Because Onimar 400 Tablet and caffeine are chemically similar, combining them can significantly increase your risk of experiencing side effects like a rapid heart rate, nervousness, and sleep issues. Talk to your doctor or pharmacist about safe dietary choices.

This medicine has a narrow safety range, meaning the difference between an effective dose and a toxic dose can be very small. Regular blood tests help your doctor monitor the amount of medicine in your body to ensure it is working safely and effectively. Talk to your doctor if you have questions about your blood test schedule.

No, you should not stop taking this medication suddenly, even if you feel completely fine. Onimar 400 Tablet is a long-term controller medicine designed to prevent breathing problems, not a quick-relief rescue treatment. Stopping it abruptly can cause your asthma or COPD symptoms to return or worsen. Talk to your doctor before making any changes to your treatment.

You must notify your doctor immediately. Tobacco smoke speeds up how quickly your body breaks down this medicine. If you stop smoking, the level of Onimar 400 Tablet in your blood can rise to dangerous levels, whereas starting smoking can make it less effective. Your doctor will need to adjust your dose safely.

No, Onimar 400 Tablet is a daily preventive controller medication and does not work quickly enough to relieve a sudden, acute asthma attack or severe shortness of breath. You must always have a fast-acting rescue inhaler on hand for sudden breathing emergencies. Talk to your doctor to create an asthma action plan.

This medicine passes into breast milk and can cross the placenta. It should only be used during pregnancy or breastfeeding if the benefits outweigh the risks and under close medical supervision. Your doctor may need to monitor your blood levels more frequently during this time. Talk to your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

If your doctor has prescribed an extended-release tablet or capsule, you must swallow it whole. Crushing, chewing, or breaking these formulations releases all of the medicine into your system at once, which can lead to serious side effects. If you have trouble swallowing tablets, talk to your doctor or pharmacist about alternative liquid options.

If you develop a high or persistent fever, or if you get a severe viral illness like the flu, you should contact your doctor right away. Severe fevers and viral infections can slow down how your body breaks down this medication, which can cause the drug to build up to toxic levels in your bloodstream. Talk to your doctor for guidance if you feel unwell.

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Country of origin

India

Manufacturer/Marketer address

DB-107, Ground Floor, Sector-I, Salt Lake City, Kolkata- 700064
Other Info - ONI0031
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