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  3. Opmet AM 50 Tablet 15's

Opmet AM 50 Tablet 15's, Pack of 15 TABLETS
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Written By Lakshmithulasi Yarragunta ,
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Opmet AM 50 Tablet is used to treat hypertension (increased blood pressure). It contains Amlodipine and Metoprolol, which widen and relax the blood vessels, making the heart more efficient at pumping blood throughout the body. Thus, it helps to lower high blood pressure, reducing the chances of heart attack or stroke. It is generally safe to consume. Some people may experience side effects such as nausea, vomiting, diarrhoea, fatigue, headache, low heart rate, and breathlessness. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

AMLODIPINE-5MG + METOPROLOL-50MG

Manufacturer/Marketer :

Opsis Care Lifesciences Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Opmet AM 50 Tablet

Opmet AM 50 Tablet belongs to the class of drugs known as antihypertensive, used to treat hypertension (increased blood pressure). Hypertension (high blood pressure) is a lifelong or chronic condition in which the force exerted by the blood against the artery walls becomes so high that it leads to heart disease. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. Lowering blood pressure may reduce the risk of stroke and heart attacks.

Opmet AM 50 Tablet contains Amlodipine and Metoprolol. Amlodipine is a calcium channel blocker, while Metoprolol belongs to a group of medicines called beta-blockers. Metoprolol relaxes blood vessels by blocking the action of certain natural substances in your body. On the other hand, Amlodipine widens and relaxes the blood vessels, making the heart more efficient at pumping blood throughout the body. Together, it helps to lower high blood pressure, reducing the chances of heart attack or stroke. Opmet AM 50 Tablet is prescribed to adults and children more than six years of age.

Opmet AM 50 Tablet can be taken with or without food as directed by your physician. Swallow the whole tablet with a glass of water. Do not crush, chew, or break it. Opmet AM 50 Tablet is preferable to take at the same time every day for better results. Opmet AM 50 Tablet is generally safe to consume. Some people may experience nausea, vomiting, diarrhoea, fatigue, headache, low heart rate, and breathlessness. Most of the side effects of Opmet AM 50 Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Don't stop taking $ name without talking to your doctor first. Stopping Opmet AM 50 Tablet gradually may cause changes in your heart rhythm and blood pressure, cause chest pain, or a heart attack. Your doctor will lower your dose gradually over time to help prevent these symptoms. It is advisable to drink plenty of fluids while taking this medicine to overcome muscle weakness, dry mouth, and extreme thirst. Do not take grapefruit or grapefruit juices with Opmet AM 50 Tablet as it can increase the concentration of Opmet AM 50 Tablet and worsen its side effects.

Uses of Opmet AM 50 Tablet

Opmet AM 50 Tablet used in the treatment of High blood pressure (hypertension), Heart-related chest pain (angina pectoris). The detailed uses of Opmet AM 50 Tablet are as follows:

Treatment of hypertension: Opmet AM 50 Tablet controls hypertension by relaxing blood vessels, reducing blood pressure, and preventing serious complications like heart attack and stroke.

Heart-related chest pain relief: Opmet AM 50 Tablet provides relief from chest pain by relaxing veins and blood vessels, and improving blood flow.

Chronic heart failure prevention: Opmet AM 50 Tablet helps prevent complications associated with chronic heart failure by reducing the extra load on the heart.

Abnormal heart rhythm control: Opmet AM 50 Tablet helps control abnormal heart rhythms by regulating heartbeats and reducing strain on the heart.

Directions for Use

  • Opmet AM 50 Tablet can be taken with or without food as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Opmet AM 50 Tablet as a whole with a glass of water.
  • Do not crush, break, or chew it.

Medicinal Benefits

  • Opmet AM 50 Tablet is used to treat high blood pressure (hypertension) and chest pain (angina), helping to improve blood flow and reduce strain on the heart.
  • It contains Amlodipine, a calcium channel blocker that relaxes and widens blood vessels by blocking the entry of calcium into heart and vessel walls, improving oxygen delivery to the heart.
  • It also contains Metoprolol, a beta-blocker that slows down the heart rate and relaxes blood vessels by blocking the effects of certain stress hormones, helping to lower blood pressure.
  • This combination reduces spasms of the coronary arteries, preventing sudden chest pain episodes and improving overall heart function.
  • It helps the heart work more efficiently, reduces its oxygen demand, and increases tolerance to physical activity, lowering the risk of angina attacks during exercise or stress.

How Opmet AM 50 Tablet Works

Opmet AM 50 Tablet contains Amlodipine and Metoprolol. Amlodipine is a calcium channel blocker, while Metoprolol belongs to a group of medicines called beta-blockers. Metoprolol relaxes blood vessels by blocking the action of certain natural substances in your body. On the other hand, Amlodipine widens and relaxes the blood vessels, making the heart more efficient at pumping blood throughout the body. Together, it helps to lower high blood pressure, reducing the chances of heart attack or stroke.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Opmet AM 50 Tablet

Do not take more than the prescribed dose. Using more medication will not improve your symptoms; rather, it may cause poisoning or serious side effects. If you suspect that you may have overdosed on Opmet AM 50 Tablet or if you experience any adverse events, please go to the emergency department of the closest hospital.

Drug Warnings

  • Do not stop taking this medicine suddenly without medical advice, as it can cause severe chest pain, abnormal heart rhythms, or even a heart attack. Your doctor will reduce the dose gradually to prevent these risks.
  • This medicine can lower your blood pressure or slow your heart rate too much, leading to dizziness, fainting, or fatigue. Inform your doctor immediately if these symptoms occur.
  • Use with caution if you have diabetes, as Metoprolol may mask the warning signs of low blood sugar and increase the risk of hypoglycemia, especially if you use insulin or other diabetes medicines.
  • Avoid using this medicine unless specifically prescribed by your doctor if you have asthma, severe breathing problems, or a history of bronchospasm, as beta-blockers like Metoprolol can worsen breathing difficulties.
  • Inform your doctor about heart conditions such as heart failure, heart block, sick sinus syndrome, or severe circulation problems, as special monitoring or dose changes may be needed.
  • Tell your doctor about all medicines, supplements, or herbal remedies you are taking (such as clonidine, digoxin, certain antidepressants, or other blood pressure drugs), as they may interact and increase the risk of side effects.

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
AmlodipinePrimidone
Severe

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
How does the drug interact with Opmet AM 50 Tablet:
Using Opmet AM 50 Tablet together with dantrolene may increase the risk of hyperkalemia (high blood potassium).

How to manage the interaction:
Taking Opmet AM 50 Tablet with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
AmlodipinePrimidone
Severe
How does the drug interact with Opmet AM 50 Tablet:
Using Opmet AM 50 Tablet and primidone together may lower Opmet AM 50 Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of Opmet AM 50 Tablet with primidone can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipinePhenobarbital
Severe
How does the drug interact with Opmet AM 50 Tablet:
Using phenobarbital and Opmet AM 50 Tablet may drastically lower Opmet AM 50 Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of phenobarbital with Opmet AM 50 Tablet can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineRifapentine
Severe
How does the drug interact with Opmet AM 50 Tablet:
Coadministration of Opmet AM 50 Tablet and Rifapentine may significantly reduce the blood levels of Opmet AM 50 Tablet, which may make the medication less effective.

How to manage the interaction:
There may be a possibility of interaction between Opmet AM 50 Tablet and Rifapentine, but it can be taken if prescribed by a doctor. If you have any symptoms, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
AmlodipineItraconazole
Severe
How does the drug interact with Opmet AM 50 Tablet:
Coadministration of Opmet AM 50 Tablet with itraconazole may significantly raise the blood levels and effects of Opmet AM 50 Tablet.

How to manage the interaction:
Opmet AM 50 Tablet and itraconazole may interact, but if prescribed by a doctor, they can be used together. Consult a doctor if you develop chest discomfort, trouble breathing, dizziness or fainting, swelling of the hands, ankles, or feet, or any other of these symptoms. Without consulting a doctor, never stop taking any medication.
AmlodipineCarbamazepine
Severe
How does the drug interact with Opmet AM 50 Tablet:
Coadministration of Opmet AM 50 Tablet and carbamazepine together may significantly reduce Opmet AM 50 Tablet blood levels, making the medicine less effective.

How to manage the interaction:
Although there is an interaction between Opmet AM 50 Tablet with carbamazepine, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms contact the doctor immediately. Do not stop using any medications without talking to a doctor.
AmlodipineLemborexant
Severe
How does the drug interact with Opmet AM 50 Tablet:
Coadministration of lemborexant and Opmet AM 50 Tablet may increase the blood levels of lemborexant.

How to manage the interaction:
Although co-administration of Opmet AM 50 Tablet with Lemborexant can result in an interaction, it can be taken if a doctor has advised it. However, consult your doctor if you experience abnormal sleep patterns, worsening of depression, changes in heartbeat, or headache. Do not discontinue any medications without consulting a doctor.
AmlodipineIdelalisib
Severe
How does the drug interact with Opmet AM 50 Tablet:
Coadministration of Opmet AM 50 Tablet and Idelalisib may raise Opmet AM 50 Tablet levels in the blood this may lead to serious side effects (irregular heart rhythm, fluid retention, swelling, heart failure, and abnormally low blood pressure).

How to manage the interaction:
Although taking Opmet AM 50 Tablet with idelalisib can result in an interaction, it can be taken if a doctor has advised it. However, if you experience dizziness or fainting, sudden, unexplained weight gain, swelling of the hands, ankles, or feet, chest discomfort, or trouble breathing while taking these drugs, consult the doctor. Use caution while getting up from a sitting or sleeping position and avoid driving or using dangerous machinery. Do not stop using any medications without a doctor's advice.
AmlodipinePhenytoin
Severe
How does the drug interact with Opmet AM 50 Tablet:
Using Opmet AM 50 Tablet and phenytoin together may drastically lower Opmet AM 50 Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although Opmet AM 50 Tablet with phenytoin can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineNitisinone
Severe
How does the drug interact with Opmet AM 50 Tablet:
Coadministration of Opmet AM 50 Tablet and Nitisinone may increase the blood levels and effects of Nitisinone.

How to manage the interaction:
Taking Nitisinone with Opmet AM 50 Tablet together can result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms or if you feel unwell after taking your medication, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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AMLODIPINE-5MG+METOPROLOL-50MGFruit juices, Fruits
Moderate

Drug-Food Interactions

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AMLODIPINE-5MG+METOPROLOL-50MGFruit juices, Fruits
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking Amlodipine and Metoprolol with grapefruit and grapefruit juice significantly increases the metabolism of Amlodipine. Avoid taking Amlodipine and Metoprolol with grapefruit and grapefruit juice.

Diet & Lifestyle Advise

  • Maintain a healthy body weight, ideally with a BMI between 18.5 and 24.9, as excess weight increases the risk of high blood pressure and heart disease.
  • Engage in regular physical activity, aiming for at least 150 minutes of moderate-intensity exercise per week (e.g., brisk walking, cycling, swimming) to help lower blood pressure by about 5–8 mmHg.
  • Limit sodium intake to ≤2300 mg per day, with an ideal goal of 1500 mg daily for adults with high blood pressure or heart problems.
  • If you drink alcohol, limit intake to up to 1 drink per day for women and up to 2 drinks per day for men, as excessive drinking can raise blood pressure.
  • Quit smoking, as it significantly increases the risk of heart attack, stroke, and complications from high blood pressure.
  • Manage stress through relaxation techniques, deep breathing, mindfulness, adequate sleep, and spending time with loved ones to help maintain stable blood pressure levels.
  • Monitor blood pressure regularly at home and keep a record. Contact your doctor promptly if you notice frequent or large fluctuations.
  • Eat a heart-healthy diet, rich in fruits, vegetables, whole grains, lean protein, and omega-3 fatty acids (from fish, flaxseeds, or walnuts) to support cardiovascular health.
  • Use healthy cooking oils such as olive, canola, or soybean oil, and limit saturated fats to help manage blood pressure and improve heart health.
  • Follow your doctor’s advice strictly regarding medications, diet, and lifestyle adjustments to reduce the risk of severe heart complications.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Opmet AM 50 Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

You are recommended not to consume alcohol along with Opmet AM 50 Tablet to avoid unpleasant side-effects.

bannner image

Pregnancy

Caution

Opmet AM 50 Tablet is not recommended during pregnancy unless your doctor considers it essential. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

bannner image

Breast Feeding

Unsafe

Opmet AM 50 Tablet is not recommended while breastfeeding. If you have any concerns regarding this, discuss them with your doctor.

bannner image

Driving

Unsafe

Opmet AM 50 Tablet is unlikely to affect your ability to drive or to operate machinery. However, some people may occasionally feel dizzy or tired when taking Propranolol. If this happens to you, ask your doctor for advice.

bannner image

Liver

Caution

Opmet AM 50 Tablet to be taken with caution, especially if you have a history of Liver diseases/conditions. The dose may have to be adjusted by your doctor.

bannner image

Kidney

Caution

Opmet AM 50 Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

bannner image

Children

Unsafe

The safety and efficacy of Opmet AM 50 Tablet in children have not been established. Opmet AM 50 Tablet is not recommended in children.

Have a query?

FAQs

Opmet AM 50 Tablet is used to treat high blood pressure (hypertension) and heart-related chest pain (angina pectoris). It widens and relaxes the blood vessels, making the heart more efficient at pumping blood throughout the body.

In case you have missed a dose of Opmet AM 50 Tablet , you are advised to take it as soon as you remember. However, try not to miss a dose in the first place. If it's time for you to take your next dose, then do not take both doses together. Take only one dose; taking a double dose of Opmet AM 50 Tablet will lead to low blood pressure.

When you are taking a beta-blocker, your health care provider may recommend that you limit your consumption of bananas and other high potassium foods, including papaya, tomato, avocado and kale.

Opmet AM 50 Tablet can be safely taken as long as your doctor has prescribed it to you. Conditions such as high blood pressure are lifelong conditions, and one should not abruptly discontinue them without consulting a doctor.

Yes, Opmet AM 50 Tablet is contraindicated in people with known allergy to any of the components of this medicine. It should be avoided in people with severe kidney or liver impairment and people with anuria (reduction or absence of urine). It should also be avoided in women who are in the second and third trimesters of their pregnancy.

It is unlikely that Opmet AM 50 Tablet affects fertility in men or women. However, there's not enough evidence to say for sure. For the best advice, consult your doctor.

Yes, Opmet AM 50 Tablet is known to cause ankle swelling. Please try to keep your feet up when sitting for long hours. If the problem persists still, consult your doctor and do as advised.

Yes, Opmet AM 50 Tablet can cause dry mouth. Therefore, it is always advised to increase fluid intake while taking Opmet AM 50 Tablet . If you still feel excessively thirsty, please consult your doctor and follow their recommendations for the best results.

No, you are advised to inform your doctor and monitor your blood pressure for at least two weeks before stopping the medicine. Depending upon your current blood pressure readings, there is a possibility your doctor may lower your medicine dosage and not recommend discontinuing it.

Common side effects of Opmet AM 50 Tablet may include nausea, vomiting, diarrhoea, fatigue, headache, low heart rate, and breathlessness. Most of the side effects of Opmet AM 50 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist, contact your doctor.

Eating well, exercising regularly, maintaining a healthy weight, quitting smoking, getting enough sleep, and managing stress are all lifestyle changes that can help lower blood pressure.

Store in a cool and dry place away from sunlight. Keep out of the sight and reach of children. To help protect the environment, avoid throwing away medicines in wastewater or household waste. Ask your doctor or pharmacist about the disposal of medicines.

In some cases, Opmet AM 50 Tablet may cause Headaches. These usually go away after the first week of taking Opmet AM 50 Tablet . If they persist, consult your doctor.

Opmet AM 50 Tablet is not recommended during pregnancy unless your doctor considers it essential. Consult your doctor. Your doctor will weigh the benefits and potential risks before prescribing it.

Yes, Opmet AM 50 Tablet can cause dizziness in some people, particularly when they first start taking it or after taking a higher dose. If this happens to you, do not drive a car, ride a bike, or operate any machinery.

Some people who use Opmet AM 50 Tablet report that their sexual urge decreases or that they are unable to achieve an erection. However, this is not a common side effect, and there is insufficient data to conclude that Opmet AM 50 Tablet is the reason. If you're having trouble with your sex life, consult your doctor.

Opmet AM 50 Tablet does not affect hormonal contraception. However, several hormonal methods of contraception, such as the combination pill, progestogen-only pill, and contraceptive patch, are generally not indicated if you have high blood pressure. Consult your doctor if you are taking or using any contraception.

If you take Opmet AM 50 Tablet , you do not have to quit doing sports. Regular exercise is beneficial because it reduces blood pressure while also keeping your heart and blood vessels in good working order. If you participate in high-level sports, keep in mind that several sports prohibit the use of metoprolol.

Metoprolol starts working after around 2 hours, but it can take up to a week to reach full effectiveness. You may not notice any difference when you take metoprolol, but that doesn't mean it is ineffective. You must continue to take your medication until advised otherwise by your healthcare provider.

Drinking alcohol can increase the risk of side effects with Opmet AM 50 Tablet . It can make you feel dizzy or lightheaded. It's best to stop drinking alcohol until you see how the medicine affects you.

Country of origin

India

Manufacturer/Marketer address

311, Patel Avenue Nr. Gurudwara, Bodakdev, S.G. Highway Ahmedabad Ahmedabad Gj 380015 In
Other Info - OPM0003

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Aug 1, 2025 | 11:06 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.medicines.org.uk/emc/files/pil.5200.pdf
  2. https://www.drugs.com/drug-interactions/amlodipine-with-metoprolol-succinate-er-172-0-1615-14142.html
  3. https://www.medicines.org.uk/emc/files/pil.5701.pdf
  4. https://www.ciplamed.com/content/metolar-am-tablets

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