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compositionComposition:RABEPRAZOLE-20MG
prescription
Prescription Medicine
info
Opra Tablet 10's
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

RABEPRAZOLE-20MG

Manufacturer/Marketer :

BRD MediLabs

Consume Type :

Oral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Opra Tablet 10's

Opra Tablet 10's is a prescription medicine used to treat conditions caused by excess stomach acid. It is commonly prescribed to help heal acid damage in the oesophagus, treat painful stomach ulcers, and manage symptoms of severe acid reflux. By lowering the amount of acid your stomach produces, it provides relief and allows your digestive tract to heal.

For the best results, you should take Opra Tablet 10's consistently every day, exactly as prescribed by your doctor. It is typically taken once daily in the morning, at least 30 minutes before eating breakfast. Making simple lifestyle adjustments, such as eating smaller meals and avoiding eating late at night, can also significantly improve how well this medicine works.

While taking Opra Tablet 10's, some people may experience mild side effects like headaches or occasional diarrhoea. These symptoms usually go away on their own, but you should contact your doctor right away if you experience severe diarrhoea, persistent muscle spasms, or joint pain. Always consult your healthcare provider if you notice any unusual or worsening symptoms.

Talk to your doctor before taking Opra Tablet 10's if you have a history of severe liver damage or osteoporosis. Do not take this if you are allergic to similar acid-reducing medicines, as this can trigger a severe allergic reaction. Your doctor will help determine if this medication is safe for your specific health needs.

This medicine can interact with certain other treatments, such as specific blood thinners or antifungal medications, by changing how your body absorbs them. Let your doctor know if you drink alcohol or smoke regularly, as these habits can increase stomach acid and reduce the effectiveness of your treatment. If you are pregnant, breastfeeding, or are an older adult, talk to your doctor or pharmacist to ensure it is safe for you.

Uses of Opra Tablet 10's

Opra Tablet 10's may be prescribed for the following acid-related gastrointestinal conditions: 

  • Gastroesophageal Reflux Disease (GERD): Opra Tablet 10's helps by reducing the backflow of stomach acid into the food pipe, which relieves painful heartburn and prevents acid-induced irritation.
  • Peptic Ulcer Disease: It aids in healing painful sores that develop on the lining of your stomach or upper small intestine by keeping acid levels low enough for the tissue to repair itself.
  • Zollinger-Ellison Syndrome: In this rare condition, where the stomach produces extreme amounts of acid, Opra Tablet 10's helps control and lower acid production to safe, manageable levels.
  • Helicobacter pylori (H. pylori) Infection: When used alongside antibiotics, Opra Tablet 10's lowers stomach acid to create an environment where the antibiotics can effectively clear the bacterial infection.
     

Key Benefits

Opra Tablet 10's helps reduce excess stomach acid, providing relief from acid-related conditions and supporting the healing of the digestive tract.

  • Relieves Heartburn and Acid Reflux: Helps reduce burning sensations, acid regurgitation, and discomfort caused by excess stomach acid.
  • Promotes Healing: Supports the healing of damage to the food pipe and stomach caused by acid irritation.
  • Helps Prevent Ulcers: Reduces stomach acid production, helping prevent the formation and recurrence of acid-related ulcers.
  • Improves Digestive Comfort: Helps reduce symptoms such as indigestion, sour stomach, and upper abdominal discomfort.
  • Provides Long-Lasting Acid Control: Offers sustained reduction of stomach acid to help manage symptoms throughout the day.
     
Side effects of Opra Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Regularly brush and floss your teeth.
  • Rinse your mouth with water and baking soda a solution to neutralize acid in the mouth. This makes your food taste as it should.
  • Drink plenty of water or non-caffeinated drinks to prevent dry mouth which may lead to altered taste.
  • Try ginger, peppermint, fruit or green teas, lemonade, ginger ale or fruit juice to help mask unpleasant tastes.
  • Try sucking on sugar-free ice pops or ice cubes to prevent dry mouth.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

Directions for Use

  • Opra Tablet 10's can be taken with or without food depending on the medical condition. However, it is preferable to take it at least 30 minutes before a meal for better efficacy.
  • It is usually taken 1-2 times daily or as prescribed by your doctor.
  • Swallow Opra Tablet 10's as a whole with a glass of water.
  • Do not crush or chew this medication.

How Opra Tablet 10's Works

Opra Tablet 10's contains rabeprazole, a proton pump inhibitor (PPI) that helps reduce the production of stomach acid. It works by blocking proton pumps, which are specialised structures in the stomach lining responsible for releasing acid into the stomach. By inhibiting these pumps, rabeprazole significantly lowers the amount of acid produced. This reduction in stomach acid helps relieve symptoms associated with acid-related conditions and creates a less irritating environment in the stomach and oesophagus. As a result, it supports the healing of inflamed tissues, erosions, and ulcers while helping to prevent further acid-related damage.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Opra Tablet 10's. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.

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Pregnancy

Caution

Please consult your doctor if you are pregnant. Your doctor will weigh the benefits and any potential risks before prescribing Opra Tablet 10's.

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Breast Feeding

Caution

Please consult your doctor if you are breastfeeding. Your doctor will decide if Opra Tablet 10's can be taken by breastfeeding mothers or not.

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Driving

Caution

Opra Tablet 10's may cause dizziness and sleepiness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Opra Tablet 10's is not recommended for children as the safety and effectiveness were not established.

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Heart

Safe if prescribed

Opra Tablet 10's can generally be used even if you have heart problems, but only under your doctor’s guidance. Consult your doctor if you have any concerns regarding it.

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Geriatrics

Caution

Opra Tablet 10's can be taken by geriatric patients, but with caution and medical supervision.

What if I have taken an overdose of Opra Tablet 10's

If you suspect you or someone else has taken too much of this medicine, seek immediate medical attention or call your local poison control centre right away

Diet & Lifestyle Advise

  • Avoid Trigger Foods: Limit foods and drinks that may worsen reflux, such as spicy foods, fried foods, chocolate, caffeine, citrus fruits, and carbonated beverages.
  • Eat Smaller Meals: Have smaller, more frequent meals instead of large meals to reduce pressure on the stomach.
  • Avoid Lying Down After Meals: Wait at least 2 to 3 hours after eating before lying down, and consider elevating the head of your bed if you experience night-time reflux.
  • Limit Alcohol and Avoid Smoking: Both alcohol and smoking can worsen acid reflux and reduce the effectiveness of treatment.
     

Have a query?

How Soon It Starts Working

The time required for Opra Tablet 10's to start to work: The time required for Opra Tablet 10's to start to work is 1 hour after administration. The time for which the effects of Opra Tablet 10's last: The effect of Opra Tablet 10's lasts for 24 hours.

What if you forget to take Opra Tablet 10's

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Storage

•Store Opra Tablet 10's in its original packaging at room temperature, ideally between 15°C and 30°C (59°F to 86°F). •Keep the medicine in a dry place away from direct light and moisture, meaning you should avoid storing it in bathroom cabinets.

Drug Warnings

  • Take Before Breakfast: Take Opra Tablet 10's at the same time each day, preferably about 30 minutes before breakfast.
  • Check Before Use: Do not take the medicine if the tablet is damaged or the packaging is broken.
  • Discuss Long-Term Use: Speak with your doctor if long-term treatment is required, as monitoring for vitamin B12 deficiency and bone health may be necessary.
  • Do Not Stop Suddenly: Consult your doctor before stopping treatment, as symptoms may return or worsen.
  • Inform Healthcare Providers: Let your doctor, dentist, or other healthcare professionals know that you are taking Opra Tablet 10's, especially before medical tests or procedures.
     

Drug-Drug Interactions

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Drug-Drug Interactions

Inform your doctor if you are taking any of the following medicines, as they may interact with Opra Tablet 10's: 

  • Antifungal medicines (like ketoconazole): Opra Tablet 10's lowers stomach acid, which can make it harder for your body to absorb these medications, reducing their effectiveness.
  • Blood thinners (like warfarin): Combining these can increase your risk of bleeding, requiring closer monitoring by your doctor.
  • Methotrexate (used for arthritis or cancer): Opra Tablet 10's may increase the levels of methotrexate in your body, which can raise the risk of side effects.

Drug-Food Interactions

  • Food: Taking this medicine with a heavy meal can delay how quickly your body absorbs it. For best results, take it on an empty stomach.

Drug-Disease Interactions

Inform your doctor if you have any of the following medical conditions before taking Opra Tablet 10's, as dose adjustments or monitoring may be required: 

  • Liver disease: If you have severe liver damage, your body may process this medicine more slowly, meaning you should discuss safe monitoring with your doctor.
  • Osteoporosis: Long-term use of this medicine can slightly increase the risk of bone fractures, so inform your doctor if you already have weak bones.
     
OmeprazoleErlotinib
Critical
OmeprazoleRilpivirine
Critical

Drug-Drug Interactions

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OmeprazoleErlotinib
Critical
How does the drug interact with Opra Tablet:
Opra Tablet can make Erlotinib less effective by reducing its absorption in the body. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Opra Tablet and Erlotinib together is not recommended as it can result in an interaction; it should be taken only if a doctor has advised it. Do not stop using any medications without talking to a doctor.
OmeprazoleRilpivirine
Critical
How does the drug interact with Opra Tablet:
Using rilpivirine together with Opra Tablet can decrease the absorption and blood levels of rilpivirine.

How to manage the interaction:
Taking Opra Tablet with Rilpivirine can cause an interaction, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
OmeprazoleTacrolimus
Severe
How does the drug interact with Opra Tablet:
Taking tacrolimus with Opra Tablet may significantly increase the blood levels of tacrolimus, which may increase the risk of serious side effects (high sugars, infections, kidney problems, hyperkalemia - high blood levels of potassium).

How to manage the interaction:
Although taking Opra Tablet with tacrolimus can lead to interaction, they can be taken if recommended by a doctor. However, consult the doctor if you experience irregular heart rhythm, palpitations (fast heartbeat), muscle spasm, tremor (shaking of hands & legs), and seizures(fits). Do not stop using any medications without talking to a doctor.
OmeprazoleMesalazine
Severe
How does the drug interact with Opra Tablet:
Co-administration of Opra Tablet with mesalazine can decrease the effects of mesalazine.

How to manage the interaction:
There could be a possible interaction between Mesalazine and Opra Tablet, but they can be taken together if a doctor has prescribed them. Do not discontinue any medications without consulting a doctor.
OmeprazoleMethotrexate
Severe
How does the drug interact with Opra Tablet:
Coadministration of Opra Tablet with methotrexate may increase the levels and side effects of Opra Tablet.

How to manage the interaction:
Although there is a possible interaction between Opra Tablet and methotrexate, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without consulting to a doctor.
OmeprazoleAtazanavir
Severe
How does the drug interact with Opra Tablet:
When taken together, Opra Tablet, through decreasing stomach acid, can reduce atazanavir absorption and blood levels, making the medication less effective.

How to manage the interaction:
Although taking Opra Tablet with atazanavir can lead to interaction, they can be taken if recommended by a doctor. Do not stop using any medications without talking to a doctor.
OmeprazoleDasatinib
Severe
How does the drug interact with Opra Tablet:
Taking Opra Tablet and Dasatinib together may decrease the blood levels of Dasatinib.

How to manage the interaction:
Although taking Opra Tablet with Dasatinib can lead to interaction, they can be taken if recommended by a doctor. If you experience any unusual symptoms, visit a doctor. Do not stop using any medications without talking to a doctor.
OmeprazolePazopanib
Severe
How does the drug interact with Opra Tablet:
Opra Tablet may interfere with pazopanib absorption and reduces its effectiveness.

How to manage the interaction:
Although taking Opra Tablet with pazopanib can lead to interaction, they can be taken if recommended by a doctor. Do not stop using any medications without talking to a doctor.
OmeprazoleCarbamazepine
Severe
How does the drug interact with Opra Tablet:
Taking Opra Tablet and carbamazepine may possibly reduce the effects of Opra Tablet, which could reduce its capacity to treat the condition.

How to manage the interaction:
Although taking Opra Tablet and carbamazepine together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without consulting a doctor.
OmeprazoleNelfinavir
Severe
How does the drug interact with Opra Tablet:
Using Opra Tablet in conjunction with nelfinavir can reduce the effectiveness of nelfinavir.

How to manage the interaction:
Although taking Opra Tablet with nelfinavir can lead to interaction, they can be taken if recommended by a doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIULCERS]

FAQs

Opra Tablet 10's is used to treat duodenal ulcers, gastro-oesophageal reflux disease (reflux of gastric contents into the oesophagus), heartburn, erosive oesophagitis (acid-related damage to the lining of the oesophagus), infections caused by Helicobacter pylori when given along with an antibiotic, and Zollinger-Ellison syndrome.

Opra Tablet 10's works by blocking the action of the enzyme known as gastric proton pump that is responsible for the production of acid. This helps in reducing the amount of acid produced, heals the ulcers and prevents the formation of new ulcers.

Do not take Opra Tablet 10's for longer than prescribed by your doctor. If long-term treatment is required, regular medical follow-up may be necessary. Prolonged use may increase the risk of vitamin B12 deficiency, low magnesium levels, bone fractures, and certain gastrointestinal infections. Consult your doctor if symptoms persist or if you require treatment beyond the recommended duration.

Do not stop taking Opra Tablet 10's without consulting your doctor, even if you feel better or your symptoms have improved. Stopping treatment too early may allow your condition to return or prevent complete healing. Continue taking Opra Tablet 10's for the duration prescribed by your doctor.

Diarrhoea might be a side-effect of Opra Tablet 10's. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Prolonged intake of Opra Tablet 10's is linked with a greater risk of Clostridium difficile-associated diarrhoea, so if you develop diarrhoea that does not improve, immediately consult a doctor.

Dry mouth could be a side effect of Opra Tablet 10's. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help stimulate saliva and thereby prevent dry mouth.

On long-term treatment, Opra Tablet 10's might increase the risk of fractures of the hip, spine, and wrist. Inform your doctor if you have osteoporosis or if you are taking corticosteroids.

Opra Tablet 10's should be used with caution in the elderly as it may cause bone weakness and increased risk of fractures if taken for longer duration.

Inform your doctor before taking Opra Tablet 10's if you are due to have Chromogranin A blood test. Opra Tablet 10's may cause abnormal blood and liver enzyme values. Inform the person doing the tests that you are taking Opra Tablet 10's. This medicine may cause dizziness and sleepiness, so drive only if you are alert.

Long term treatment with Opra Tablet 10's may cause malabsorption of vitamin B12 leading to its deficiency. Consult the doctor if you notice symptoms of cyanocobalamin deficiency like tiredness, sore mouth, mouth ulcers and pins & needles sensation.

Opra Tablet 10's is usually best taken on an empty stomach, preferably about 30 minutes before a meal, unless otherwise directed by your doctor. Taking it before food helps it work more effectively by reducing stomach acid production.

Side effects of Opra Tablet 10's include headache, dizziness, diarrhoea, constipation, nausea, vomiting, flatulence (wind), weakness, and runny nose. Consult the doctor if the side effects persist or worsen.

The safety of this medicine during pregnancy is not fully established. If you are pregnant or planning to become pregnant, talk to your doctor to weigh the benefits and risks.

While alcohol does not directly stop the medicine from working, drinking alcohol can irritate your stomach lining and make your acid reflux symptoms worse. Talk to your doctor for personalised advice.

No, you should swallow the tablet whole with a glass of water. Crushing or chewing it damages the special coating that protects the medicine from stomach acid. Talk to your pharmacist if you have difficulty swallowing pills.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Electronic Medicines Compendium (EMC). Pil.2842 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026] Check here
  2. U.S. Food and Drug Administration (FDA). 020973S035204736S005Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026] Check here
  3. National Health Service (NHS). Rabeprazole - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026] Check here
  4. Drugs.com Clinical Review Team. Rabeprazole Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026] Check here
  5. Drugs and Lactation Database (LactMed) [Internet]. 2006. [Accessed on 20 Feb. 2020] Check here
  6. CiplaMed CiplaMed. [Accessed on 25 Jul. 2023] Check here
  7. Rabeprazole Rabeprazole. 2025. [Accessed on 07 Jul. 2025]Check here

Country of origin

India

Manufacturer/Marketer address

No. 23, Dic Industrial Area, Baddi, Himachal Pradesh - 173205, India
Other Info - OPR0041

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