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compositionComposition:AMOXAPINE-100MG
prescription
Prescription Medicine
info
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Oradem 100 Tablet is used to treat depression, anxiety, and agitation. It contains Amoxapine, a second-generation tricyclic dibenzoxazepine antidepressant. It works by increasing the level of certain chemicals (GABA) in the brain that are responsible for mental health and mood changes. This medicine helps improve mood and feelings.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

AMOXAPINE-100MG

Manufacturer/Marketer :

Ryon Pharma

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Oradem 100 Tablet

Oradem 100 Tablet is a prescription medication primarily used to treat depression. It is especially helpful for patients experiencing depressive symptoms accompanied by anxiety, tension, or agitation. This medication belongs to a class of drugs that help restore balance to certain chemical messengers in the brain.

To get the best results, you must take Oradem 100 Tablet consistently every day exactly as your doctor prescribes. You can take this medicine with or without food, though taking it with meals can help prevent stomach upset. Incorporating a regular sleep schedule, eating a balanced diet, and engaging in light daily physical activity can also support your treatment outcomes.

While taking this medicine, some people may experience common side effects like drowsiness, dry mouth, or constipation. If you face specific serious side effects, such as unusual muscle stiffness, tremors, a rapid heartbeat, or sudden changes in your mental state, you should consult your doctor right away.

Before you begin taking Oradem 100 Tablet, tell your doctor if you have a history of heart disease, seizures, glaucoma, or difficulty urinating. Do not take this if you are currently recovering from a recent heart attack. It is also important that you do not take this if you have used certain other antidepressant medicines within the last two weeks.

This medicine can interact with other drugs that make you sleepy, and drinking alcohol while taking it can dangerously increase drowsiness. Additionally, smoking may change how quickly your body processes this medication. If you are pregnant, planning to become pregnant, breastfeeding, or are an elderly individual, you should consult your doctor or pharmacist to discuss the risks and benefits before starting treatment.

Uses of Oradem 100 Tablet

Oradem 100 Tablet is used to treat depression. The detailed uses of Oradem 100 Tablet are as follows:

  • Depression: Oradem 100 Tablet helps relieve persistent sadness, loss of interest in activities, and fatigue by balancing critical chemicals in the brain.
  • Depression with anxiety or agitation: It helps calm nervous tension and restlessness that frequently occur alongside depressive disorders.
  • Severe or psychotic depression: It helps manage severe depressive states, including those where individuals experience distorted thoughts or see and hear things that are not there.

Key Benefits

Oradem 100 Tablet helps manage depression and anxiety by restoring the balance of important brain chemicals. With regular use as prescribed, it helps improve mood, reduce anxiety symptoms, and support better emotional well-being.

  • Improves Mood: By balancing key neurotransmitters in the brain, this medicine helps reduce symptoms of depression, improve emotional well-being, and make it easier to return to daily activities.
  • Reduces Anxiety Symptoms: This medicine helps relieve anxiety-related symptoms such as excessive worry, restlessness, and physical tension, promoting a greater sense of calm.
  • Promotes Better Sleep and Daily Functioning: By improving mood and reducing anxiety, this medicine supports healthier sleep patterns, improves concentration, and helps you feel more rested and better able to manage everyday responsibilities.
Side effects of Oradem 100 Tablet
  • Get enough sleep. Maintain a regular sleep cycle.
  • Eat a healthy diet and exercise regularly.
  • Manage stress with yoga or meditation.
  • Limit alcohol and caffeine.
  • Avoid driving or operating machinery unless you are alert.
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.

Directions for Use

  • Oradem 100 Tablet can be taken with or without food as directed by the doctor.
  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Swallow Oradem 100 Tablet as a whole with a glass of water.
  • Do not break, chew or crush Oradem 100 Tablet.

How Oradem 100 Tablet Works

Oradem 100 Tablet contains amoxapine, which works by increasing the levels of certain natural chemicals in your brain, specifically norepinephrine and serotonin. These chemicals act as messengers between your brain cells and are essential for regulating your mood, emotions, and overall sense of well-being. In addition to boosting these mood-regulating chemicals, Oradem 100 Tablet blocks a chemical pathway called dopamine. This combined action is highly unique and makes the medicine particularly effective at quieting overactive brain signals, helping to relieve severe anxiety, agitation, and extreme mood disturbances.
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Alcohol

Unsafe

Alcohol should be avoided while on treatment with Oradem 100 Tablet as it can affect you much more and may make you feel more depressed.

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Pregnancy

Consult your doctor

If you are pregnant or planning pregnancy inform your doctor before taking Oradem 100 Tablet. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

If you are breastfeeding, inform your doctor before receiving Oradem 100 Tablet. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Unsafe

Oradem 100 Tablet may cause drowsiness and impair your concentration. Hence, it is advised not to drive or operate machines while on treatment with Oradem 100 Tablet.

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before taking Oradem 100 Tablet. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor before taking Oradem 100 Tablet. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Oradem 100 Tablet is not recommended for use in children below 16 years of age as the safety and efficacy are not established.

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Heart

Caution

Oradem 100 Tablet should be avoided if you have heart problems, especially a history of heart attack or arrhythmias. It may cause serious cardiac side effects like QTc prolongation, tachycardia, or sudden death. Always consult your doctor for safer alternatives.

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Geriatrics

Caution

Oradem 100 Tablet should be used with caution in geriatric patients due to increased sensitivity to side effects like dizziness, confusion, and heart rhythm changes. Close medical supervision is essential to ensure safe use.

What if I have taken an overdose of Oradem 100 Tablet

In case of an accidental overdose, seek immediate emergency medical attention. Symptoms of an overdose may include extreme drowsiness, confusion, rapid heart rate, severe muscle shaking, or fainting.

Diet & Lifestyle Advise

  • Drink plenty of fluids and consume high-fibre foods, such as fresh fruits, vegetables, and whole grains, to help prevent constipation caused by this medicine.
  • Sip water, suck on ice chips, or chew sugar-free gum to relieve dry mouth symptoms.
  • Completely avoid alcohol while taking this medicine, as it can worsen sedation and dizziness.
  • Stand up slowly from a sitting or lying position to prevent dizziness and reduce your risk of falling.
  • Establish a consistent bedtime routine to support healthy sleep habits, which can aid your recovery from depression.
health query

Have a query?

How Soon It Starts Working

The time required for Oradem 100 Tablet to start to work: The onset time of Oradem 100 Tablet has not been clinically established. The time for which the effects of Oradem 100 Tablet last: The duration of Oradem 100 Tablet’s effect is clinically not established.

What if you forget to take Oradem 100 Tablet

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store Oradem 100 Tablet tablets at room temperature, ideally between 68°F and 77°F (20°C to 25°C).

Drug Warnings

  • Do not stop taking Oradem 100 Tablet suddenly, as this can cause withdrawal symptoms like headache, nausea, or a general feeling of discomfort.
  • Wear sunscreen and protective clothing when outdoors, as this medication can make your skin more sensitive to sunlight.
  • Do not drive, operate machinery, or perform hazardous activities until you are certain how this medicine affects your alertness.
  • Ask family members or close friends to help monitor you for sudden changes in mood, worsening depression, or unusual behaviors, especially during the first few weeks of treatment.
  • Inform your dentist, surgeon, or emergency room physician that you are taking Oradem 100 Tablet before undergoing any medical procedures or surgeries.

Drug-Drug Interactions

verifiedApollotooltip
  • Monoamine Oxidase Inhibitors (MAOIs): Do not take this medicine if you have taken an MAOI antidepressant within the last 14 days, as combining them can cause dangerously high blood pressure or a life-threatening brain reaction.
  • Sedatives and Sleep Medicines: Taking this medication with other drugs that cause drowsiness, such as sleeping pills, opioid pain relievers, or muscle relaxants, can cause extreme sedation and slow breathing.
  • Blood Pressure Medications: Oradem 100 Tablet may interfere with how certain blood pressure medications work, potentially reducing their effectiveness.
AmoxapineTranylcypromine
Critical
AmoxapineMetoclopramide
Critical

Drug-Drug Interactions

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AmoxapineTranylcypromine
Critical
How does the drug interact with Oradem 100 Tablet:
Taking tranylcypromine with Oradem 100 Tablet can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Oradem 100 Tablet with Tranylcypromine is not recommended, but can be taken if prescribed by a doctor. However, consult a doctor if you have symptoms such as confusion, hallucination, fits, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
AmoxapineMetoclopramide
Critical
How does the drug interact with Oradem 100 Tablet:
Co-administration of Metoclopramide with Oradem 100 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Metoclopramide with Oradem 100 Tablet is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmoxapineZiprasidone
Critical
How does the drug interact with Oradem 100 Tablet:
Co-administration of Oradem 100 Tablet with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although there is an interaction between Ziprasidone and Oradem 100 Tablet but can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
AmoxapineSafinamide
Critical
How does the drug interact with Oradem 100 Tablet:
Taking Safinamide with Oradem 100 Tablet can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Safinamide with Oradem 100 Tablet is not recommended, as it can possibly result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting your doctor.
AmoxapineBupropion
Severe
How does the drug interact with Oradem 100 Tablet:
Taking bupropion with Oradem 100 Tablet may raise the chance of seizures(fits), which can happen with either medicine. Furthermore, bupropion can raise Oradem 100 Tablet levels in the blood, which may exacerbate other adverse effects.

How to manage the interaction:
Co- administration of bupropion along with Oradem 100 Tablet can possibly lead to an interaction, it can be taken if recommended by a doctor. Do not discontinue any medications without consulting a doctor.
AmoxapineTetrabenazine
Severe
How does the drug interact with Oradem 100 Tablet:
The combined use of Tetrabenazine and Oradem 100 Tablet can increase the risk of an irregular heart rhythm and the severity of side effects associated with Tetrabenazine.

How to manage the interaction:
Co-administration of Tetrabenazine and Oradem 100 Tablet can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like muscle spasms or movements that you can't stop or control, such as lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, tremor, jitteriness, restlessness, pacing, and foot tapping, fever, heat intolerance, excessive sweating, stiffness, difficulty moving or swallowing, sudden dizziness, lightheadedness, fainting, and fast or pounding heartbeats, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
AmoxapineMoxifloxacin
Severe
How does the drug interact with Oradem 100 Tablet:
Using Moxifloxacin together with Oradem 100 Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Moxifloxacin with Oradem 100 Tablet can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you experience dizziness, irregular heart rhythm, or difficulty breathing, it is important to contact a doctor right away. Do not stop using any medications without talking to a doctor.
AmoxapineTrazodone
Severe
How does the drug interact with Oradem 100 Tablet:
Taking Trazodone with Oradem 100 Tablet can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Co-administration of Trazodone with Oradem 100 Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience confusion, seizure(fits), extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm, tremor(shaking of hands & legs), incoordination, stomach pain, nausea, vomiting, and diarrhea contact your doctor right away. Do not discontinue any medications without first consulting your doctor.
AmoxapineVilazodone
Severe
How does the drug interact with Oradem 100 Tablet:
When Vilazodone is taken with Oradem 100 Tablet, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
There may be a possibility of interaction between Vilazodone and Oradem 100 Tablet, but it can be taken if prescribed by a doctor. If you notice any of these signs - like confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea-call a doctor right away. Do not stop using any medications without a doctor's advice.
AmoxapineVenlafaxine
Severe
How does the drug interact with Oradem 100 Tablet:
When venlafaxine is combined with Oradem 100 Tablet, can cause serotonin syndrome (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Although taking Venlafaxine and Oradem 100 Tablet together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience any of the following symptoms: confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea, seek immediate medical attention. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Grapefruit and Grapefruit Juice: Consuming grapefruit products may alter how your body breaks down this medicine, potentially increasing the risk of side effects.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIDEPRESSANT]

FAQs

It is not known whether Oradem 100 Tablet is completely safe during pregnancy or while breastfeeding. It should only be used if your doctor believes the benefits outweigh the potential risks. Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding before starting this medicine.
No, you should avoid alcohol while taking this medicine. Alcohol can significantly increase drowsiness, dizziness, and confusion, and it can also make your depression symptoms worse. Talk to your doctor or pharmacist if you have concerns.
Yes, some patients experience an increased appetite and subsequent weight gain while taking this medication. Maintaining a balanced diet and exercising regularly can help manage this side effect. Talk to your doctor if you experience significant changes in your weight.
No, it is advised not to stop taking Oradem 100 Tablet suddenly as it can cause withdrawal symptoms like suicidal thoughts, irritability, and excessive aggression, which can sometimes be fatal. So, please consult your doctor; the doctor might lower your dose depending on your medical condition.
Yes, drowsiness is a very common side effect, especially when you first start taking the medicine. Your doctor may recommend taking your dose at bedtime to help manage this. Avoid driving if you feel sleepy, and talk to your doctor if the sleepiness does not improve.
Yes, this medication can affect your heart rhythm and heart rate, particularly if you already have a heart condition. If you experience a very fast or irregular heartbeat, seek medical attention immediately. Talk to your doctor before starting this medicine if you have any heart issues.
Dry mouth is a common side effect of this class of medication. You can manage this by sipping water throughout the day, chewing sugar-free gum, or sucking on ice chips. If the dry mouth is severe or causes dental issues, talk to your doctor or pharmacist.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India
Other Info - ORAD134
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