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  3. Panderm-KZ Tablet 10's

Panderm-KZ Tablet 10's, Pack of 10
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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Panderm-KZ Tablet 10's is an antifungal medicine used in the treatment of fungal infections such as blastomycosis, coccidioidomycosis, paracoccidioidomycosis, and histoplasmosis (lung infection caused by Histoplasma fungus). This medicine works by inhibiting the growth and multiplication of fungal cells that are responsible for the growth of infection-causing fungi.
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Composition :

KETOCONAZOLE-200MG

Manufacturer/Marketer :

Macleods Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Panderm-KZ Tablet 10's

Panderm-KZ Tablet 10's belongs to a class of drugs called antifungals indicated to treat various systemic fungal infections such as blastomycosis (infection caused by Blastomyces fungus), chromomycosis (chronic infection of the skin and subcutaneous tissue), Coccidioidomycosis (infection caused by Coccidioides fungus), paracoccidioidomycosis (infection caused by Paracoccidioides fungus) and histoplasmosis (lung infection caused by Histoplasma fungus). It is used only when other effective antifungal therapies are not available or tolerated and if potential benefits outweigh potential risks.

Panderm-KZ Tablet 10's contains Ketoconazole which works by destroying fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, kills fungi and treats the fungal infection.

Take Panderm-KZ Tablet 10's as prescribed. Your doctor will advise you on how often you need to take Panderm-KZ Tablet 10's based on your medical condition. Some people may experience headache, nausea, stomach pain, and diarrhoea. Most of these side effects of Panderm-KZ Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

If you are allergic to Ketoconazole or any other medicines, please tell your doctor. If you are pregnant or planning for pregnancy, inform your doctor before taking Panderm-KZ Tablet 10's. Avoid breastfeeding while taking Panderm-KZ Tablet 10's as it may be excreted in breast milk. You are recommended to avoid alcohol consumption whilst on treatment with Panderm-KZ Tablet 10's. Panderm-KZ Tablet 10's is not recommended for children below 2 years of age. For children above 2 years, it is recommended to use only if the doctor has determined that the benefits outweigh the risks.

Uses of Panderm-KZ Tablet 10's

Treatment of Systemic fungal infections

Directions for Use

• Panderm-KZ Tablet 10's can be taken with or without food. • Your doctor will decide the dose and duration depending on your condition.• Swallow the medicine as a whole with a glass of water.• Do not crush, chew, or break Panderm-KZ Tablet 10's as it may affect the way the medication is absorbed.

Medicinal Benefits

Panderm-KZ Tablet 10's is an antifungal used to treat severe fungal infections. It is used only when other effective antifungal therapies are not available or tolerated and if potential benefits outweigh potential risks. It destroys fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, kills fungi and treats the fungal infection.

How Panderm-KZ Tablet 10's Works

Panderm-KZ Tablet 10's contains Ketoconazole which works by destroying fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, kills fungi and treats the fungal infection.

Storage

• Store in a cool and dry place away from sunlight.
• Keep Panderm-KZ Tablet 10's out of the sight and reach of children.
• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Panderm-KZ Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

What if I have taken an overdose of Panderm-KZ Tablet 10's

Never take more than the prescribed dose. When Panderm-KZ Tablet 10's is used at high doses, it may, though unlikely, result in decreased testosterone levels, sperm production, and an issue with the adrenal glands (adrenal insufficiency). Seek emergency medical help if an overdose is suspected.

Drug Warnings

If you are allergic to Ketoconazole or any other medicines, please tell your doctor. If you are pregnant or planning for pregnancy, inform your doctor before taking Panderm-KZ Tablet 10's. Avoid breastfeeding while taking Panderm-KZ Tablet 10's as it may be excreted in breast milk. You are recommended to avoid alcohol consumption with Panderm-KZ Tablet 10's. If you have a loss of appetite, tiredness, stomach pain, vomiting, yellowing of skin or eyes, dark urine, or light-coloured stools, inform your doctor immediately as they might be symptoms of hepatotoxicity (liver damage). 

Drug-Drug Interactions

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KetoconazolePimozide
Critical
KetoconazoleLovastatin
Critical

Drug-Drug Interactions

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KetoconazolePimozide
Critical
How does the drug interact with Panderm-KZ Tablet:
When Pimozide is taken with Panderm-KZ Tablet, it can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Panderm-KZ Tablet with Pimozide is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
KetoconazoleLovastatin
Critical
How does the drug interact with Panderm-KZ Tablet:
Coadministration of Lovastatin with Panderm-KZ Tablet can increase the risk of liver damage, rhabdomyolysis (the breakdown of skeletal muscle tissue) which may lead to kidney damage.

How to manage the interaction:
Taking Panderm-KZ Tablet with Lovastatin is not recommended as it can cause an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms like unexplained muscular pain, tenderness, weakness, accompanied by fever, dark urine or unexpected bruising or bleeding, skin rash, itching, vomiting, yellowing of the skin or eyes, chills, joint pain, swelling, consult a doctor immediately. Do not discontinue any medication without consulting a doctor.
KetoconazoleSilodosin
Critical
How does the drug interact with Panderm-KZ Tablet:
Coadministration of Silodosin with Panderm-KZ Tablet may lead to side effects including extremely low blood pressure, and increased heart rate.

How to manage the interaction:
Taking Panderm-KZ Tablet with Silodosin together is not recommended as it can result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, headache, flushing, nasal congestion, heart palpitation. Do not discontinue any medications without consulting a doctor.
KetoconazoleMethylergometrine
Critical
How does the drug interact with Panderm-KZ Tablet:
Using Panderm-KZ Tablet with Methylergometrine can increase the concentration of Methylergometrine, which may lead to side effects.

How to manage the interaction:
Taking Panderm-KZ Tablet with Methylergometrine is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. Do not discontinue any medication without consulting a doctor.
KetoconazoleMethadone
Critical
How does the drug interact with Panderm-KZ Tablet:
When Methadone is taken with Panderm-KZ Tablet, it can increase the risk of serious side effects such as respiratory problems, low blood pressure, irregular heart rhythm.

How to manage the interaction:
Taking Panderm-KZ Tablet with Methadone is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. However, if you experience breathing difficulty, fainting, heart palpitations, consult the doctor immediately. Do not discontinue any medication without consulting a doctor.
KetoconazoleNimodipine
Critical
How does the drug interact with Panderm-KZ Tablet:
When Nimodipine is taken with Panderm-KZ Tablet, it can increase the blood levels of Nimodipine which may lead to serious side effects .

How to manage the interaction:
Taking Panderm-KZ Tablet with Nimodipine is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. However, if you experience -irregular heart rhythm, swelling, and low blood pressure, consult the doctor. Do not discontinue any medications without consulting the doctor.
KetoconazoleDofetilide
Critical
How does the drug interact with Panderm-KZ Tablet:
When Dofetilide is taken with Panderm-KZ Tablet, it can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Panderm-KZ Tablet with Dofetilide is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
KetoconazoleTolvaptan
Critical
How does the drug interact with Panderm-KZ Tablet:
When Tolvaptan is taken with Panderm-KZ Tablet, may increase the risk of side effects.

How to manage the interaction:
Taking Tolvaptan with Panderm-KZ Tablet is not recommended as it can lead to an interaction, it can be taken if prescribed by a doctor. However, if you notice any of these signs -difficulty swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, mood changes, seizures, call a doctor right away. Do not stop using any medications without a doctor's advice.
KetoconazoleAlfuzosin
Critical
How does the drug interact with Panderm-KZ Tablet:
Using alfuzosin together with Panderm-KZ Tablet may significantly increase the blood levels of alfuzosin, which may result in side effects.

How to manage the interaction:
Taking Alfuzosin with Panderm-KZ Tablet is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience fainting, headache, flushing, nasal congestion, or heart palpitation, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
KetoconazoleNaloxegol
Critical
How does the drug interact with Panderm-KZ Tablet:
When Naloxegol is taken with Panderm-KZ Tablet, it can increase the blood levels of naloxegol which may cause the side effects.

How to manage the interaction:
Taking Panderm-KZ Tablet with Naloxegol is not recommended as it can cause an interaction, but it can be taken if prescribe by the doctor. However, if you experience symptoms such as sweating, tearing, runny nose, chills, diarrhea, stomach pain, anxiety, difficulty sleeping, irritability, restlessness, and yawning, consult the doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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KETOCONAZOLE-200MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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KETOCONAZOLE-200MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consumption of grapefruit or its juice with Panderm-KZ Tablet may result in side effects such as joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, dark urine, light colored stools, and yellowing of the skin or eyes. Avoid consuming grapefruit, grapefruit juice, or any supplements that include grapefruit extract while taking Panderm-KZ Tablet.

Diet & Lifestyle Advise

  • Avoid high-risk areas such as renovated buildings, construction sites, pigeon or chick coops, and caves.
  • Wear a respiratory mask when there is a risk of exposure to spores.
  • People with a weak immune system are advised to avoid activities that involve close contact with dust or dirt including digging, yard work, and gardening.
  • Close windows and stay inside during dust storms.
  • Clean skin injuries well with soap and water to reduce the risk of developing a skin infection.

Habit Forming

No

Therapeutic Class

ANTIFUNGALS - ORAL

Panderm-KZ Tablet 10's Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Panderm-KZ Tablet 10's as it may increase the risk of liver damage and cause adverse effects.

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Pregnancy

Caution

Panderm-KZ Tablet 10's is a Category C pregnancy drug and is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Unsafe

Panderm-KZ Tablet 10's may be excreted in breast milk. Therefore, it is recommended to avoid breastfeeding while taking Panderm-KZ Tablet 10's.

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Driving

Caution

Panderm-KZ Tablet 10's may cause dizziness or drowsiness. Therefore, drive only if you alert after taking Panderm-KZ Tablet 10's.

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Liver

Unsafe

Panderm-KZ Tablet 10's is contraindicated in patients with chronic or acute liver disease. Therefore, inform your doctor if you have any Liver diseases/conditions.

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Kidney

Caution

If you have any concerns regarding the use of Panderm-KZ Tablet 10's in patients with kiver diseases/conditions, consult a doctor.

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Children

Caution

Panderm-KZ Tablet 10's is not recommended for children below 2 years of age. For children above 2 years, it is recommended to use only if the doctor has determined that benefits outweigh risks.

Have a query?

FAQs

Panderm-KZ Tablet 10's belongs to a class of drugs called antifungals indicated to treat various systemic fungal infections such as blastomycosis (infection caused by Blastomyces fungus), chromomycosis (chronic infection of the skin and subcutaneous tissue), Coccidioidomycosis (infection caused by Coccidioides fungus), paracoccidioidomycosis (infection caused by Paracoccidioides fungus) and histoplasmosis (lung infection caused by Histoplasma fungus).

Panderm-KZ Tablet 10's works by destroying fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, kills fungi and treats the fungal infection.

Panderm-KZ Tablet 10's is not recommended to treat fungal meningitis (fungal infection spreads to the brain and spinal cord) as it poorly penetrates into the cerebrospinal fluid. Therefore, inform your doctor if you have fungal meningitis so that appropriate medication may be prescribed.

You are recommended to avoid foods containing chocolate and caffeine such as cocoa beans, tea, coffee, cola and energy drinks while taking Panderm-KZ Tablet 10's as it may increase the adverse effects of caffeine such as drowsiness, nervousness or nausea.

You are not recommended to take Panderm-KZ Tablet 10's with simvastatin (lipid-lowering drug) as co-administration of these medicines may cause muscle problems. Therefore, please consult a doctor before taking Panderm-KZ Tablet 10's with other medicines.

No, you are not recommended to stop taking Panderm-KZ Tablet 10's without consulting your doctor as it may cause recurring infection. Therefore, take Panderm-KZ Tablet 10's for as long as your doctor has prescribed it and if you experience any difficulty while taking Panderm-KZ Tablet 10's, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, India.
Other Info - PAN2575

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Santoshini Reddy GDoctor badge

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Jul 18, 2025 | 9:24 AM IST

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Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/018533s040lbl.pdf
  2. https://www.drugs.com/mtm/ketoconazole.html
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