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compositionComposition:PANCREATIN-350MG
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Panmate 25000 Capsule is used for the treatment of exocrine pancreatic insufficiency (pancreatin enzyme deficiency) due to cystic fibrosis (an inherited disorder that damages the lungs and digestive system), chronic pancreatitis (inflammation of the pancreas), or other conditions. It contains Pancreatin, which helps in the digestion of food. In some cases, it may cause certain common side effects such as nausea, mild stomach pain, diarrhoea, and mild skin rash. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

PANCREATIN-350MG

Manufacturer/Marketer :

Hetero Healthcare Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Panmate 25000 Capsule

Panmate 25000 Capsule is an oral enzyme replacement therapy used to treat digestive difficulties caused by a lack of natural digestive enzymes in the body. It is commonly prescribed for individuals whose pancreas does not produce enough enzymes to digest food properly, which can happen due to long-term pancreas swelling, cystic fibrosis, or after surgical removal of the pancreas.

To achieve the best results, you must take Panmate 25000 Capsule consistently with every meal and snack. Always take this medication during your meals with a full glass of water, and consider adopting a balanced, lower-fat diet with smaller, more frequent meals to support your digestive health.

While taking Panmate 25000 Capsule , some people may experience mild stomach-related side effects, such as bloating, nausea, or mild stomach discomfort. If you notice any severe side effects, such as intense abdominal pain or a severe skin rash, you should contact your doctor right away.

Do not take this if you have a known allergy to pork proteins, as these digestive enzymes are sourced from pigs. Before you begin taking this medication, talk to your doctor if you have a history of gout, kidney problems, or bowel blockages.

This medication can interact with other substances, including certain antacids and iron supplements, which may reduce its effectiveness or absorption. If you are pregnant, planning a pregnancy, breastfeeding, or are an elderly individual, consult your doctor or pharmacist to ensure this therapy is safe and appropriate for your specific needs.

Uses of Panmate 25000 Capsule

Panmate 25000 Capsule is used to replace digestive enzymes when the pancreas cannot produce enough of them on its own. It helps improve the digestion and absorption of nutrients in people with conditions that affect pancreatic function, including:

  • Pancreatic Exocrine Insufficiency: Panmate 25000 Capsule helps replace missing digestive enzymes, allowing your body to properly break down and absorb nutrients from the food you eat.
  • Chronic Pancreatitis: It supplements the reduced enzyme production caused by long-term inflammation of the pancreas, preventing malnutrition.
  • Cystic Fibrosis: It assists in digesting fats, proteins, and carbohydrates when thick mucus blocks the natural flow of enzymes from the pancreas into the small intestine.
  • Post-Pancreas Surgery: It serves as a vital replacement for enzymes when a portion of the pancreas, or the entire organ, has been surgically removed.

Key Benefits

By supporting the digestion of fats, proteins, and carbohydrates, Panmate 25000 Capsule provides several important digestive and nutritional benefits, including:

  • Improves Food Digestion: Helps the body break down nutrients more effectively, supporting normal digestive function.
  • Reduces Digestive Discomfort: Helps relieve symptoms such as bloating, excess gas, abdominal discomfort, and indigestion after meals.
  • Enhances Nutrient Absorption: Improves the absorption of essential vitamins, minerals, and other nutrients from food.
  • Helps Prevent Weight Loss: Supports proper calorie and nutrient uptake, reducing the risk of unintended weight loss associated with poor digestion.
  • Reduces Greasy or Oily Stools: Helps improve fat digestion, decreasing symptoms such as fatty, foul-smelling stools.
  • Supports Overall Nutritional Health: By improving nutrient utilisation, it can help reduce fatigue and nutritional deficiencies linked to pancreatic enzyme insufficiency.
Side effects of Panmate 25000 Capsule

Directions for Use

  • Panmate 25000 Capsule should be taken immediately after a meal or snack.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Panmate 25000 Capsule as a whole with a glass of water.
  • You may also open the capsules and mix the granules (do not crush them) with soft foods like yoghurt or applesauce, or with an acidic liquid such as apple, pineapple, or orange juice. Consume the mixture immediately.
  • Do not crush or chew this medication.

How Panmate 25000 Capsule Works

Panmate 25000 Capsule contains a combination of digestive enzymes that help your body break down and absorb nutrients from food when the pancreas is unable to produce enough enzymes on its own. Lipase is an enzyme that helps break down fats into smaller substances called fatty acids, which can be easily absorbed by the body. Amylase is an enzyme that breaks down complex carbohydrates and starches into simpler sugars, making them easier for the body to digest and use for energy. Protease is an enzyme that breaks down proteins from food into amino acids, which are essential for growth, repair, and normal body functions. These enzymes are specially formulated to resist destruction by stomach acid, allowing them to reach the small intestine where digestion takes place. Together, these enzymes help improve the digestion and absorption of fats, proteins, and carbohydrates, reducing symptoms such as bloating, gas, abdominal discomfort, and fatty stools caused by pancreatic enzyme deficiency.
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Alcohol

Caution

It is unknown whether alcohol interacts with Panmate 25000 Capsule . Please consult your doctor if you have any concerns regarding this.

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Pregnancy

Caution

Panmate 25000 Capsule belongs to pregnancy category C. Consult your doctor before taking Panmate 25000 Capsule if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

It is unknown whether Panmate 25000 Capsule passes into breast milk. Consult your doctor before taking Panmate 25000 Capsule ; your doctor will decide whether breastfeeding mothers can take Panmate 25000 Capsule or not.

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Driving

Caution

Panmate 25000 Capsule does not affect your ability to drive. However, Panmate 25000 Capsule may cause dizziness. So, do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed. Consult your doctor before taking Panmate 25000 Capsule if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Consult your doctor before taking Panmate 25000 Capsule if you have kidney impairment or any concerns regarding this.

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Children

Safe if prescribed

Panmate 25000 Capsule can be given to children if prescribed by the doctor. The dose depends upon the child’s age and body weight.

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Heart

Consult your doctor

Consult your doctor before taking Panmate 25000 Capsule if you have heart problems or any concerns regarding this.

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Geriatrics

Safe if prescribed

Panmate 25000 Capsule can be given safely to the elderly if advised by the doctor.

What if I have taken an overdose of Panmate 25000 Capsule

Taking too much of this medicine can cause high levels of uric acid in your blood or urine, or lead to severe constipation. If you suspect an overdose, drink plenty of water and seek immediate medical attention or contact a poison control center.

Diet & Lifestyle Advise

  • Eat smaller, more frequent meals: Eating five to six small meals throughout the day instead of three large ones can make food easier to digest and reduce stomach strain.
  • Manage fat intake: Work closely with a dietitian to ensure you are consuming healthy fats in amounts that your prescribed dose of Panmate 25000 Capsule can manage.
  • Stay hydrated: Drink plenty of water throughout the day to support healthy digestion and help prevent constipation.
  • Avoid alcohol and smoking: Both alcohol and tobacco can irritate your pancreas, worsen your digestive symptoms, and lower the effectiveness of your therapy.

Have a query?

How Soon It Starts Working

The time required for Panmate 25000 Capsule to start to work: The time required for Panmate 25000 Capsule to show its action is not clinically established. The time for which the effects of Panmate 25000 Capsule last: The duration of action for Panmate 25000 Capsule is not clinically established.

What if you forget to take Panmate 25000 Capsule

If you forget to take Panmate 25000 Capsule with a meal or snack, skip the missed dose and take your regular dose with your next meal. Do not take a double dose or extra medicine to make up for a missed one. If you have already finished eating and forgot the dose, do not take it, as it will not be effective without food.

Storage

•Store Panmate 25000 Capsule at room temperature, ideally between 15°C and 25°C (59°F to 77°F). •Keep the container tightly closed to protect the medication from moisture.

Drug Warnings

  • Never skip food: Always take Panmate 25000 Capsule with food; taking it without food can cause severe irritation to your stomach lining.
  • Do not chew the beads: If you open the capsules to mix them with soft food, swallow the mixture immediately without chewing to prevent mouth irritation.
  • Do not switch brands: Different brands of this medication may not work the same way in your body. Always consult your pharmacist or doctor before changing products.
  • Keep the bottle sealed: These enzymes are highly sensitive to moisture and can lose their strength quickly if the container is left open.
  • Watch for severe stomach pain: Contact your doctor immediately if you experience severe, persistent stomach pain, as this can be a sign of a rare but serious bowel issue.

Drug-Drug Interactions

verifiedApollotooltip

Panmate 25000 Capsule can interact with certain medicines that affect digestion or nutrient absorption, potentially altering treatment effectiveness or nutritional status, including:

  • Calcium or magnesium-based antacids: Taking these antacids at the same time may reduce the effectiveness of Panmate 25000 Capsule .
  • Iron supplements: This medication may decrease the absorption of iron in your body, potentially requiring your doctor to monitor your iron levels.

 

No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

verifiedApollotooltip

Certain foods can affect how Panmate 25000 Capsule works, particularly when capsules are opened and mixed with food, including:

  • Alkaline (non-acidic) foods: If opening the capsules, do not mix the medicine with milk, ice cream, custard, or other alkaline foods, as this can destroy the protective coating of the enzymes before they reach your intestines.
     
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ENZYMES]

FAQs

Panmate 25000 Capsule is used to treat Pancreatic insufficiency (pancreatin enzyme deficiency).
Panmate 25000 Capsule contains pancreatin enzymes that break down food and convert it into energy. Panmate 25000 Capsule is a combination of amylase (to digest starch), protease (to digest protein), and lipase (to digest fat). Together, it fulfils the digestive enzymes' requirements in conditions such as pancreatitis (inflammation of the pancreas), cystic fibrosis (a genetic disorder that damages the lungs), pancreatic cancer, pancreatectomy (surgical removal of the pancreas), and steatorrhea (loose fatty stool due to poor fat absorption).
Panmate 25000 Capsule might interfere with the absorption and reduce the effectiveness of folic acid and iron. To prevent this, maintain a minimum gap between both.
Diarrhoea might be a side-effect of Panmate 25000 Capsule . Drink enough fluids and eat non-spicy food if you experience diarrhoea. Consult your doctor if you experience watery diarrhoea or if you find blood in your stools. Do not take anti-diarrhoeal medicine on your own.
Mixing Panmate 25000 Capsule with non-acidic food or liquids, chewing or crushing may cause irritation in the mouth. It might also change the way Panmate 25000 Capsule works in the body. Do not hold Panmate 25000 Capsule or its contents in your mouth.
To treat your condition effectively, continue taking Panmate 25000 Capsule for as long as your doctor has prescribed it. Many patients will need to take Panmate 25000 Capsule for the rest of their lives. Do not hesitate to consult your doctor if you experience any difficulties while taking Panmate 25000 Capsule .
Pancreatin is a pancreatic enzyme derived from the pancreatic organs of pigs used for food. Consult your doctor before taking Panmate 25000 Capsule if you are allergic to the pig (pork), cow products or buffalo products.
Panmate 25000 Capsule may cause side effects such as nausea, mild stomach pain, diarrhoea, and mild skin rash. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
Panmate 25000 Capsule is safe to be used in children if prescribed by the doctor. The dose is determined by the child’s age and body weight.
Take Panmate 25000 Capsule during or immediately after eating a meal or a snack, and drink plenty of water.
Include fruits, vegetables, whole grains, lean meats, poultry without skin, fish, yoghurt, cheese, and non-fat/low-fat milk. Avoid high-fat, deep-fried, and buttered foods.
No, you should not take Panmate 25000 Capsule on an empty stomach. The enzymes in the medication require food to work and can irritate your stomach lining if taken without a meal or snack. Talk to your doctor if you have questions about your dosing schedule.
You can open the capsule and mix the contents with a small amount of acidic soft food, such as applesauce. Swallow this mixture immediately without chewing, and follow with a glass of water. Talk to your doctor or pharmacist if you need further help.
You should consult your healthcare provider before using Panmate 25000 Capsule if you are pregnant or breastfeeding. Your doctor will weigh the benefits and potential risks to decide if it is safe for you. Talk to your doctor to discuss your options.
Yes, Panmate 25000 Capsule is typically prescribed as a long-term treatment for chronic conditions where the pancreas does not produce enough enzymes. Your doctor will monitor your progress and adjust your dose as needed. Talk to your doctor about your long-term care.
Panmate 25000 Capsule helps your body absorb nutrients and fats properly, which can lead to healthy weight gain or weight maintenance if you have previously lost weight due to malabsorption. It does not cause abnormal weight gain. Talk to your doctor if you have concerns about your weight.
It is highly recommended to avoid alcohol while taking this medicine. Alcohol can damage your pancreas, worsen your underlying condition, and interfere with how well the medicine works. Talk to your doctor about your alcohol consumption.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

INDIA

Manufacturer/Marketer address

A/201-202, Dipti Classic, 32/34 Surendra Road, Andheri (E), Mumbai Maharashtra 400093 India
Other Info - PAN1645
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