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compositionComposition:ITOPRIDE-150MG-SUSTAINED+PANTOPRAZOLE-40MG
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Prescription Medicine
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Pantabrex-IT Capsule 10's is used to treat acidity, GERD (gastro-oesophagal reflux disease), and peptic ulcers. It contains Pantoprazole and Itopride, which decrease the production of acid. Additionally, it works by accelerating gastric emptying and improving gastric sensitivity and tone. It also has anti-emetic action. Thus, it helps in preventing acid reflux, thereby providing relief from acidity. In some cases, you may experience certain common side effects such as headache, nausea, stomach pain, dizziness and diarrhoea. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

ITOPRIDE-150MG-SUSTAINED+PANTOPRAZOLE-40MG

Manufacturer/Marketer :

Cambrex Life Sciences

Consume Type :

Oral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Pantabrex-IT Capsule 10's

Pantabrex-IT Capsule 10's is a prescription medication used to treat gastroesophageal reflux disease (GERD), acid reflux, and functional dyspepsia. It helps relieve uncomfortable symptoms like chronic heartburn, sour burps, and stomach fullness by addressing both excessive acid production and slow digestion. This medication is typically prescribed to restore comfort to your upper digestive tract.

To get the best results, you should take this medicine consistently every day, exactly as directed by your doctor. It is highly recommended to take it on an empty stomach, usually in the morning before your first meal. Incorporating simple habits like eating smaller meals and avoiding heavy, spicy, or fatty foods can significantly support the medication's effectiveness.

While taking Pantabrex-IT Capsule 10's, some people may experience mild side effects like headache, gas, or slightly loose stools. Most of these symptoms go away on their own as your body adjusts. However, if you experience serious issues such as severe, watery diarrhoea, joint pain, or muscle spasms, you should contact your doctor immediately.

Do not take this if you have a known blockage, tear, or active bleeding in your stomach or intestines. Before starting this medication, it is vital to tell your doctor if you have severe liver damage, kidney issues, or a history of bone thinning (osteoporosis).

This medicine can interact with other substances, such as certain blood thinners, antifungals, and alcohol, which can increase stomach irritation. If you are pregnant, breastfeeding, or managing health conditions as an older adult, talk to your doctor or pharmacist to ensure this treatment is safe for your specific situation.

Uses of Pantabrex-IT Capsule 10's

Pantabrex-IT Capsule 10's is prescribed to treat acid-related digestive disorders and symptoms associated with delayed stomach emptying, including:

  • Gastroesophageal Reflux Disease (GERD): Pantabrex-IT Capsule 10's helps by reducing the amount of acid your stomach produces, preventing acid from backing up into your food pipe and causing painful heartburn.
  • Functional Dyspepsia: This medicine relieves symptoms of persistent indigestion, such as early fullness during meals, bloating, and upper abdominal pain, by helping food pass through your stomach more efficiently.
  • Acid Reflux with Delayed Stomach Emptying: It assists in clearing acid and digested food from the stomach quickly, reducing nausea and preventing the regurgitation of sour fluids.
     

Key Benefits

Pantabrex-IT Capsule 10's offers the following benefits when used as prescribed:

  • Relieves heartburn and acid reflux: It reduces stomach acid production, helping to relieve the burning sensation in the chest and throat caused by acid reflux.
  • Improves stomach emptying: By enhancing the movement of food through the digestive tract, it helps reduce symptoms related to delayed gastric emptying.
  • Reduces bloating and post-meal discomfort: It helps alleviate feelings of fullness, heaviness, and abdominal bloating that may occur after eating.
  • Decreases nausea and regurgitation: Faster stomach emptying can reduce the likelihood of food and stomach contents moving back into the food pipe.
  • Supports healing of the food pipe: Long-term control of stomach acid helps protect and heal the irritated lining of the oesophagus, reducing the risk of further acid-related damage.
  • Improves overall digestive comfort: By addressing both excess acid and slow digestion, it helps patients feel more comfortable during and after meals.
     

Directions for Use

To get the best results from Pantabrex-IT Capsule 10's, follow these instructions carefully:

  • Take this medicine on an empty stomach: It is typically taken by mouth once daily, at least 30 to 60 minutes before breakfast, or as directed by your doctor.
  • Swallow the capsule whole: Take it with a full glass of water. Do not crush, chew, or break the capsule, as this can damage the special coating and affect how the medicine works.
  • Take it at the same time each day: Consistent timing helps maintain steady symptom control and improves treatment effectiveness.
  • Follow your prescribed treatment duration: Continue taking the medicine for the full period recommended by your doctor, even if your symptoms improve before treatment is completed.
  • Do not change the dose without medical advice: Always follow your doctor's instructions regarding the dose and frequency of use.
     

How Pantabrex-IT Capsule 10's Works

Pantabrex-IT Capsule 10's works through the combined action of its two active ingredients, pantoprazole and itopride, which target your digestive system in different, complementary ways. The first active ingredient, pantoprazole, is an acid reducer. It works by temporarily shutting down the tiny acid-producing pumps in your stomach lining, which dramatically lowers the volume of acid your stomach secretes. The second active ingredient, itopride, is a movement-promoting agent. It stimulates the muscles in your stomach and upper intestines, accelerating the rate at which your stomach empties food into your bowels and helping to keep digestive fluids moving in the right direction.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Pantabrex-IT Capsule 10's. Alcohol intake leads to increased production of stomach acid, thereby increases acidity and heartburn.

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Pregnancy

Caution

Consult your doctor before taking Pantabrex-IT Capsule 10's if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Pantabrex-IT Capsule 10's; your doctor will decide whether Pantabrex-IT Capsule 10's can be taken by breastfeeding mothers or not.

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Driving

Caution

Pantabrex-IT Capsule 10's may cause dizziness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed. Consult your doctor before taking Pantabrex-IT Capsule 10's if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Consult your doctor before taking Pantabrex-IT Capsule 10's if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Pantabrex-IT Capsule 10's should not be given to children as safety and effectiveness were not established.

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Heart

Caution

Exercise caution while taking Pantabrex-IT Capsule 10's, if you have any heart problems. Please consult your physician.

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Geriatrics

Caution

Exercise caution while giving Pantabrex-IT Capsule 10's in elderly patients. Please consult your physician.

What if I have taken an overdose of Pantabrex-IT Capsule 10's

Do not take more than the prescribed dose of Pantabrex-IT Capsule 10's as it may cause an overdose. The symptoms of overdose include fever, back pain, slow/irregular heartbeat, rash, pain while peeing or blood in urine (signs of kidney problems) or stomach pain that worsens (sign of an inflammed liver or pancreas). If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Eat Smaller, More Frequent Meals: Eat smaller, more frequent meals throughout the day instead of three large ones to avoid putting excess pressure on your stomach.
  • Avoid Late-Night Eating: Avoid eating within 3 to 4 hours of lying down or going to sleep to keep stomach acid from traveling upward naturally.
  • Identify and Avoid Trigger Foods: Identify and limit foods that trigger your reflux, such as fried or fatty foods, chocolate, caffeine, citrus juices, tomatoes, and spicy dishes.
  • Elevate Your Head While Sleeping: Elevate the head of your bed by 6 to 8 inches using bed risers or a firm wedge pillow to help keep acid down while you sleep.
  • Wear Loose-Fitting Clothing: Wear loose-fitting clothing around your waist to minimize physical pressure on your abdomen.
     
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How Soon It Starts Working

The time required for Pantabrex-IT Capsule 10's to start to work: Pantabrex-IT Capsule 10's ideally shows its action within 30 minutes to 1 hour after administration. The time for which the effects of Pantabrex-IT Capsule 10's last: The duration of action for Pantabrex-IT Capsule 10's is unknown.

What if you forget to take Pantabrex-IT Capsule 10's

If you miss a dose of Pantabrex-IT Capsule 10's, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for the missed one.

Storage

•Store Pantabrex-IT Capsule 10's at room temperature, preferably below 25°C, or as directed on the product packaging. •Keep the capsules in their original blister pack or container to protect them from moisture, heat, and direct sunlight.

Drug Warnings

  • Take on an Empty Stomach: Always take Pantabrex-IT Capsule 10's on an empty stomach, at least half an hour before your first meal, for the medication to work as intended.
  • Do Not Stop Treatment Abruptly: Do not stop taking this medicine suddenly without consulting your doctor, as doing so can cause your acid symptoms to return worse than before.
  • Monitor Vitamin and Mineral Levels During Long-Term Use: If you need to take this medicine for more than a few weeks, your doctor may monitor your vitamin and mineral levels, as long-term acid reduction can interfere with how your body absorbs Vitamin B12 and magnesium.
  • Inform Your Medical Team Before an Endoscopy: Inform your medical team if you are scheduled for an endoscopy, as this medicine can mask certain signs of stomach conditions and may need to be paused beforehand.
  • Seek Medical Attention for Severe Digestive Symptoms: Contact your doctor immediately if you develop a fever, severe stomach cramping, or watery diarrhoea that does not improve.
     

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Drug-Drug Interactions

The following medications may affect how Pantabrex-IT Capsule 10's works or increase the risk of side effects:

  • Medicines that require stomach acid for absorption: PANTOPRAZOLE may decrease the absorption and effectiveness of medications such as ketoconazole, itraconazole, and certain antiviral medicines that depend on stomach acid for proper absorption.
  • Blood thinners: Taking this medicine with anticoagulants such as warfarin may increase the risk of bleeding and may require closer monitoring.
  • Anticholinergic medications: Medicines used for conditions such as bladder overactivity, motion sickness, or intestinal cramps may reduce the gut-stimulating effects of ITOPRIDE, making the combination less effective.

Drug-Food Interactions

Certain foods and beverages may affect your treatment or worsen your symptoms, including:

  • Alcohol: Avoid drinking alcohol while taking this medicine, as alcohol can increase stomach irritation, worsen acid reflux symptoms, and reduce the overall effectiveness of treatment.

Drug-Disease Interactions

Some medical conditions may affect the safety or effectiveness of Pantabrex-IT Capsule 10's, including:

  • Gastrointestinal obstruction, perforation, or bleeding: Do not take this medicine if you have an active blockage, perforation, or bleeding in the digestive tract, as increased gut movement may worsen these conditions.
  • Liver or kidney disease: Use with caution if you have impaired liver or kidney function, as dose adjustments or closer monitoring may be required.
  • History of bone fractures or osteoporosis: Long-term use of proton pump inhibitors such as pantoprazole may be associated with an increased risk of bone fractures, particularly in individuals with existing risk factors.
     

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Habit Forming

No

Therapeutic Class

[GASTROINTESTINAL AGENTS]

FAQs

Pantabrex-IT Capsule 10's is used to treat acidity, GERD (gastro-oesophagal reflux disease), and peptic ulcers.
Pantabrex-IT Capsule 10's is a combination of two drugs, namely: Pantoprazole and Itopride. Pantoprazole works by blocking the action of an enzyme called gastric proton pump, responsible for the production of acid. Itopride works by accelerating gastric emptying and improves gastric sensitivity and tension. Together, Pantabrex-IT Capsule 10's helps in preventing acid reflux, thereby provides relief from acidity.
Avoid lying down immediately after meals to prevent acid reflux. Raise the head of the bed 10-20cm by putting a pillow so that the head and chest are above the waist. This helps in preventing acid reflux.
Yes, Pantabrex-IT Capsule 10's may cause constipation as a side effect. It can be minimized by drinking plenty of water or eating foods that will help you stay hydrated and also increase your intake of high-fibre foods like raw fruits, whole grains, and vegetables.
No, a single dose of Pantabrex-IT Capsule 10's is usually not sufficient for treating conditions like GERD (gastro-oesophageal reflux disease) or peptic ulcers. Therefore, it’s important to follow your doctor's instructions and complete the full course of treatment to see full benefits.
Pantabrex-IT Capsule 10's is generally considered safe when taken as prescribed by your doctor. Do not exceed the recommended daily dose.
Long-term use of Pantabrex-IT Capsule 10's, especially at high doses or for prolonged periods, may increase the risk of osteoporosis, bone fractures, hypomagnesemia (low magnesium levels), and certain vitamin deficiencies. Your doctor may recommend monitoring or supplementation if long-term treatment is necessary.
No, do not stop taking Pantabrex-IT Capsule 10's without consulting your doctor, even if you start feeling better. Stopping Pantabrex-IT Capsule 10's too early may cause your symptoms to return or worsen, and it might not fully treat the underlying condition. Always follow your doctor's instructions and complete the full course of treatment to ensure the best results.
Weight gain is not a common side effect of Pantabrex-IT Capsule 10's. However, the long-term use of proton pump inhibitors (PPIs) like pantoprazole may indirectly cause weight gain through changes in appetite and food intake. To overcome this side effect, follow a balanced diet and consult your doctor. If you have any concerns, consult your doctor.
No. It is recommended to avoid alcohol while taking Pantabrex-IT Capsule 10's because alcohol can irritate the stomach lining, increase acid production, worsen heartburn and reflux symptoms, and reduce the effectiveness of treatment.
Yes, you can take antacids 2 hours before or after taking Pantabrex-IT Capsule 10's, to prevent any possible interactions, this allows the antacids to work effectively without interfering with the absorption of Pantabrex-IT Capsule 10's. However, please consult a doctor before taking other medicines with Pantabrex-IT Capsule 10's.
To get relieve from acidity, include high-fibre foods like whole grains, vegetables and fruits, alkaline foods such as cauliflower, fennel, and nuts, watery foods like celery, cucumber, lettuce, and watermelon, lean proteins and ginger as they can help reduce acid reflux symptoms.
You are recommended to consult a doctor before taking pain killers along with Pantabrex-IT Capsule 10's.
The common side effects of Pantabrex-IT Capsule 10's are headache, nausea, stomach pain, dizziness and diarrhoea. If any of these side effects persist or worsen, please consult your doctor.
Take Pantabrex-IT Capsule 10's exactly as prescribed by your doctor. It is recommended to take it on an empty stomach, preferably 30–60 minutes before food, usually before breakfast. Taking it with or after food may reduce its effectiveness. If you have difficulty following this schedule, consult your doctor.
Pantabrex-IT Capsule 10's starts working within a few hours of taking a dose. Some people may notice relief from symptoms such as heartburn, acidity, or bloating within 1–3 days. However, it may take several days to a few weeks of regular use to achieve the full benefit, depending on the condition being treated.
The safety of Pantabrex-IT Capsule 10's during pregnancy has not been fully established. It should only be used if your doctor determines that the medical benefit to you outweighs any potential risk to the baby. Talk to your doctor if you are pregnant or planning to become pregnant.
Take Pantabrex-IT Capsule 10's only for the duration prescribed by your doctor. If your symptoms do not improve after 14 days, consult your doctor. Long-term use without medical supervision may increase the risk of osteoporosis, bone fractures, hypomagnesemia, and vitamin deficiencies.
Yes, diarrhoea can occur as a side effect of Pantabrex-IT Capsule 10's. Drink plenty of fluids and eat non-spicy foods if you develop mild diarrhoea. However, if the diarrhoea is severe, persistent, watery, associated with fever or stomach cramps, or if you notice blood in your stools, contact your doctor immediately. Do not take anti-diarrhoeal medicines without medical advice.
No, you must swallow Pantabrex-IT Capsule 10's whole with water. Crushing, chewing, or breaking the capsule destroys its special protective coating, which prevents the medicine from being destroyed prematurely by stomach acid. Talk to your doctor or pharmacist if you have persistent trouble swallowing capsules.

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Country of origin

India

Manufacturer/Marketer address

Cambrex Life Sciences
Other Info - PAN2609

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