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compositionComposition:PARACETAMOL-1000MG
prescription
Prescription Medicine
info
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Paranir Injection is an antipyretic and analgesic medicine used in the treatment of mild to moderate pain and fever. This medicine contains paracetamol which works by inhibiting the release of chemical messengers called prostaglandins that cause pain and inflammation. Some of the common side effects include constipation, nausea, and vomiting, and injection site reactions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

PARACETAMOL-1000MG

Manufacturer/Marketer :

Elite Pharmaceuticals, Inc

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Paranir Injection

Paranir Injection is an intravenous medication primarily used for the short-term relief of moderate pain, especially after surgical procedures. It is also highly effective at rapidly reducing high body temperature in patients suffering from severe fever. This medication is typically prescribed in hospital or clinical settings when oral treatments are not suitable or when fast-acting relief is medically necessary.

This injection is given at regular intervals or on an as-needed basis as scheduled by your healthcare provider. Because it is delivered directly into a vein, food intake does not affect how it works. To support your recovery, your doctor may suggest simple lifestyle adjustments such as resting in a comfortable, quiet room and staying well-hydrated.

While this medication is generally well-tolerated, some individuals may experience mild side effects like nausea, headache, or localised pain at the injection site. However, if you experience rare but serious symptoms, such as severe skin rashes, yellowing of your eyes or skin, or breathing difficulties, you must alert your medical team immediately.

Before receiving this medicine, tell your doctor if you have a history of liver disease, kidney disease, or severe dehydration. Do not receive this medicine if you have a known allergy to Paranir Injection or any of its ingredients, or if you have severe liver failure (severe hepatocellular insufficiency). Also tell your doctor if you have phenylketonuria (PKU) or a known allergy to any inactive ingredients in the formulation, as some brands may contain different excipients.

This injection can interact with certain other medicines, especially other pain relievers or blood thinners, which can increase the risk of liver damage or bleeding. It is also vital to avoid alcohol while receiving this medication to protect your liver. If you are pregnant, breastfeeding, or managing health conditions as an elderly individual, talk to your doctor to discuss safe usage.

Uses of Paranir Injection

Your doctor may prescribe Paranir Injection to help manage the following conditions:

  • Moderate pain after surgery: Paranir Injection helps manage post-operative pain quickly and effectively when you are unable to swallow oral medications.
  • Severe fever reduction: Paranir Injection works rapidly to lower high body temperature when oral cooling methods or medications are not practical or fast enough.

Key Benefits

When used as directed as part of your treatment plan, this medicine may provide the following benefits:

  • Fast Relief: Because Paranir Injection is injected directly into your bloodstream, it bypasses your digestive tract entirely. This allows the medication to begin working almost immediately, offering rapid relief from intense pain or high fever when every minute counts.
  • When IV Is Preferred: Additionally, this treatment is highly beneficial for patients who are unable to keep oral medications down due to severe nausea, vomiting, or recent stomach and bowel surgeries. It ensures you receive consistent, reliable pain control and fever relief during critical recovery periods.
Side effects of Paranir Injection 100 ml
  • Tell your doctor about any pain or discomfort at the infusion site.
  • Apply a warm compress to reduce swelling and ease pain.
  • Switch infusion sites to avoid irritating the same spot.
  • Practice calming techniques like deep breathing, meditation, or yoga to manage pain and anxiety.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of Paranir Injection to ensure its safe and effective use.
  • Paranir Injection will be administered by a healthcare professional in a hospital.
  • Do not self-administer this medication.

How Paranir Injection Works

Paracetamol works centrally in the brain and spinal cord to block the chemical messengers that transmit pain signals to your body. It also acts directly on the temperature-regulating centre of your brain to help lower a high fever. By instantly entering your bloodstream through an intravenous line, it provides fast, reliable comfort and stabilisation without the delay of digestive absorption.
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Paranir Injection . Alcohol intake, along with Paranir Injection may cause increased liver damage.

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Pregnancy

Consult your doctor

Please consult your doctor before taking Paranir Injection if you are a pregnant.

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Breast Feeding

Consult your doctor

Paranir Injection should be used during breastfeeding only when suggested by a doctor.

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Driving

Safe if prescribed

Paranir Injection does not usually affect your ability to drive.

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Liver

Consult your doctor

Please consult your doctor since Paranir Injection should be used with caution in patients with liver impairment/liver disease.

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Kidney

Consult your doctor

Please consult your doctor since Paranir Injection should be used with caution in patients with kidney impairment/kidney disease.

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Children

Caution

Paranir Injection should be given to children only when prescribed by a doctor

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Heart

Safe if prescribed

Paranir Injection is generally considered safe for heart patients when used at recommended doses. However, please consult your doctor if you have any concerns.

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Geriatrics

Safe if prescribed

Paranir Injection is considered safe for elderly patients when administered at recommended doses; however, liver function and total daily dosage should be monitored to prevent toxicity.

What if I have taken an overdose of Paranir Injection

Because a professional administers this injection, an overdose is very rare. However, receiving too much of this medicine can cause severe liver damage. If you suspect an overdose has occurred, or if you experience delayed symptoms such as severe nausea, vomiting, loss of appetite, or abdominal pain, seek immediate emergency medical care.

Diet & Lifestyle Advise

  • Stay hydrated: Drink plenty of water (if your doctor allows) to help your body recover and support healthy liver and kidney function.
  • Prioritise rest: Give your body ample time to rest and heal, particularly if you are recovering from a surgical procedure.
  • Avoid alcohol: Strictly avoid alcoholic beverages while receiving this treatment, as alcohol significantly increases the risk of serious liver damage.
  • Eat light, balanced meals: Once you are cleared to eat, opt for easy-to-digest, nutrient-rich foods to help rebuild your strength without straining your stomach.
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How Soon It Starts Working

The time required for Paranir Injection to start to work: Paranir Injection shows its action within 1 hour of administration. The time for which the effects of Paranir Injection last: Paranir Injection effect last for 4 to 6 hours.

What if you forget to take Paranir Injection

Since this medication is given in a controlled hospital or clinic environment by professional healthcare staff, it is highly unlikely that you will miss a dose. If you believe a scheduled dose has been missed, notify your nurse or doctor immediately.

Storage

•Store this injection at room temperature, ideally below 30°C (86°F). Do not refrigerate or freeze the solution.

Drug Warnings

  • Inspect the Vial: Ensure your nurse or doctor inspects the vial before use; the solution must be clear and free from any floating particles.
  • Share Your Medical History: Always inform your healthcare team if you have a history of liver disease, kidney issues, or chronic malnutrition before the injection is given.
  • Avoid Duplicate Medicines: Double-check with your medical team to ensure you are not taking any other over-the-counter or prescription pain relievers that contain the same active ingredient, as this can lead to accidental liver damage.
  • Pregnancy and Breastfeeding: Alert your doctor if you are pregnant, planning to become pregnant, or breastfeeding before receiving this therapy.

Drug-Drug Interactions

verifiedApollotooltip
  • Blood thinners: Regular, prolonged use of this medication may increase the risk of bleeding when combined with blood thinners like warfarin.
  • Other pain relievers: Combining this injection with other medicines containing the same active ingredient can easily lead to an accidental overdose and severe liver damage.
  • Certain anti-seizure or TB medicines: Medications used to treat seizures or tuberculosis may increase the risk of liver strain when used alongside this treatment.
ParacetamolLomitapide
Severe
ParacetamolLeflunomide
Severe

Drug-Drug Interactions

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ParacetamolLomitapide
Severe
How does the drug interact with Paranir Injection 100 ml:
Co-administration of Lomitapide and Paranir Injection 100 ml may increase the risk of severity of liver injury.

How to manage the interaction:
Although there is a possible interaction between Paranir Injection 100 ml and Lomitapide, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
ParacetamolLeflunomide
Severe
How does the drug interact with Paranir Injection 100 ml:
Co-administration of Paranir Injection 100 ml and Leflunomide may increase the risk of liver problems.

How to manage the interaction:
Although there is a possible interaction between Paranir Injection 100 ml and Leflunomide, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ParacetamolValdecoxib
Severe
How does the drug interact with Paranir Injection 100 ml:
Co-administration of Paranir Injection 100 ml and Valdecoxib may increase the risk or severity of adverse effects.

How to manage the interaction:
Although there is a possible interaction between Paranir Injection 100 ml and Valdecoxib, you can take these medicines together if prescribed by a doctor. However, if the side effects worsen, please consult a doctor.
ParacetamolKetoconazole
Severe
How does the drug interact with Paranir Injection 100 ml:
Co-administration of Paranir Injection 100 ml and Ketoconazole may increase the risk of liver injury.

How to manage the interaction:
Although there is a possible interaction between Paranir Injection 100 ml and Ketoconazole, you can take these medicines together if prescribed by a doctor. However, if you have joint pain or swelling, fever, chills, unusual bleeding or bruising, skin rash, itching, over-tiredness, nausea, vomiting, loss of appetite, stomach pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact a doctor immediately as these may be signs and symptoms of liver damage. Do not discontinue the medication without consulting a doctor.
ParacetamolTeriflunomide
Severe
How does the drug interact with Paranir Injection 100 ml:
Co-administration of Teriflunomide with Paranir Injection 100 ml may increase the risk or severity of Liver problems.

How to manage the interaction:
Taking Paranir Injection 100 ml with Teriflunomide together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
ParacetamolOxazepam
Severe
How does the drug interact with Paranir Injection 100 ml:
Co-administration of Paranir Injection 100 ml may decrease the excretion rate of Oxazepam which could result in a higher serum level.

How to manage the interaction:
Although there is a possible interaction between Oxazepam and Paranir Injection 100 ml, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
ParacetamolMipomersen
Severe
How does the drug interact with Paranir Injection 100 ml:
Co-administration of Mipomersen with Paranir Injection 100 ml may increase the risk or severity of liver injury.

How to manage the interaction:
There may be a possibility of interaction between Paranir Injection 100 ml and Mipomersen, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
ParacetamolKetamine
Severe
How does the drug interact with Paranir Injection 100 ml:
Co-administration of ketamine and Paranir Injection 100 ml may decrease the effectiveness of Ketamine which could result in a higher blood level.

How to manage the interaction:
Although taking Ketamine and Paranir Injection 100 ml together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you're feeling very sleepy or having trouble breathing, it's important to contact your doctor right away. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
  • Alcohol: Consuming alcohol while using this medicine severely increases the risk of acute liver damage and must be avoided completely.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANALGESIC AND ANTIPYRETIC AGENT]

FAQs

Paranir Injection is used to relieve mild to moderate pain and to treat fever. Pain is a symptom triggered by the nervous system, which causes uncomfortable sensations in the body. Fever occurs when the body's temperature exceeds the average (98.6°F or 37°C).
Paranir Injection works by blocking the effect of chemical messengers (prostaglandins), thereby reducing fever, pain, stiffness, swelling, and inflammation.
It is not advised to take Paranir Injection on your own. You should use Paranir Injection only if a healthcare professional prescribes it.
Paranir Injection is to be cautiously used in case of any allergic reactions to other pain killers. Let your doctor know your medical history before starting Paranir Injection .
Though Paranir Injection is usually safe to use, it may very rarely cause serious skin reactions like generalized exanthematous pustulosis (AGEP), Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis (TEN). Please discontinue the usage of Paranir Injection if you notice any skin rash and consult your doctor immediately.
It is generally considered safe for short-term use during pregnancy when clinically necessary, but it should only be used under strict medical supervision. Talk to your doctor to weigh the risks and benefits for your specific situation.
Mild pain, redness, or swelling at the injection site is common and usually resolves quickly. However, if the pain becomes severe, warm, or swollen, tell your nurse or doctor immediately. Talk to your doctor if the discomfort persists.
No, you must avoid alcohol while receiving this medication. Alcohol significantly increases the risk of severe, life-threatening liver damage. Talk to your doctor or pharmacist if you have concerns about alcohol use.
This medication typically does not cause drowsiness or impair your mental alertness. However, post-surgical fatigue or other medications given alongside it might make you feel tired. Talk to your doctor if you feel unusually fatigued or dizzy.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

1210/11/12 G.I.D.C., Phase III, Vatva, Ahmedabad - 382 445. Gujarat-India
Other Info - PAR0645

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