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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Pentasa 1 gm Suppository is used to treat ulcerative colitis. It contains Mesalazine, which helps reduce inflammation (redness and swelling) in the intestines and provides relief from symptoms such as stomach pain or bleeding. It may cause side effects such as diarrhoea, stomach pain, headache or nausea.

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Composition :

MESALAZINE-1000MG

Manufacturer/Marketer :

Ferring Pharmaceuticals Pvt Ltd

Consume Type :

RECTAL

Return Policy :

Not Returnable

Expires on or after :

About Pentasa 1 gm Suppository

Pentasa 1 gm Suppository is used to treat ulcerative colitis and ulcerative proctitis. Ulcerative colitis is a chronic inflammatory bowel disease that causes inflammation of the large intestine lining (colon). Ulcerative proctitis is a condition in which ulcerative colitis solely affects the rectum.

Pentasa 1 gm Suppository contains Mesalazine, which works by preventing the synthesis of chemical messengers such as prostaglandins in the intestines that produce inflammation (swelling).

Sometimes, you may experience diarrhoea, stomach pain, headache or nausea. Most of these side effects of Pentasa 1 gm Suppository do not require medical attention and typically resolve on their own over time. However, if the side effects persist or worsen, please consult your doctor.

Follow your doctor's instructions on the dosage and timing of this medication. Pentasa 1 gm Suppository is for rectal use only. It is advised to wash your hands before and after applying the medicament. Ensure the rectal area is clean and dry before application.

Inform your doctor if you are allergic to any components present in Pentasa 1 gm Suppository. Pentasa 1 gm Suppository should be used with caution in the elderly. If you are pregnant or breastfeeding, please inform your doctor before taking Pentasa 1 gm Suppository. Avoid taking Pentasa 1 gm Suppository if you have severe kidney failure. If you have stomach pain, cramps, severe headache, fever or rash, after taking Pentasa 1 gm Suppository, stop taking it immediately and consult a doctor.

Uses of Pentasa 1 gm Suppository

Pentasa 1 gm Suppository is used in the treatment of Ulcerative colitis and Ulcerative proctitis. The detailed uses of Pentasa 1 gm Suppository are as follows:

  • Management of Irritable Bowel Syndrome (IBS): Pentasa 1 gm Suppository helps manage IBS symptoms like bloating, gas, and abdominal discomfort.
  • Support for Ulcerative Colitis: Pentasa 1 gm Suppository supports ulcerative colitis management by reducing flare-ups and promoting gut health.
  • Restoration of Gut Flora Post-Antibiotics: Pentasa 1 gm Suppository helps to restore beneficial gut bacteria after antibiotic use.

Have a query?

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Check the label for directions and use it as advised by the doctor. 
  • Before using, empty your bowels (if necessary) and wash your hands. Shake the bottle vigorously for at least 30 seconds. Remove the applicator's protective cap and hold the bottle by its top end. Lie on your left side, your left leg extended and your right leg bent. Insert the applicator (lubricant-coated) for easier entry into the rectum. Squeeze the bottle gently while holding it directed towards your navel. When the bottle is empty, remove the applicator from the rectum. Allow the drug to spread throughout the lower section of the large intestine for at least 30 minutes by remaining in this posture.
  • Wash your hands before and after applying the medicament. Ensure the rectal area is clean and dry before application.
  • For rectal use only.

Medicinal Benefits

  • Pentasa 1 gm Suppository contains Mesalamine, an anti-inflammatory drug used to treat ulcerative colitis and ulcerative proctitis.
  • This medicine helps reduce inflammation (redness and swelling) in the intestines and provides relief from symptoms such as stomach pain or bleeding.
  • Pentasa 1 gm Suppository may also prevent further episodes of ulcerative colitis.

How Pentasa 1 gm Suppository Works

Pentasa 1 gm Suppository contains Mesalazine, which works by inhibiting the production of certain chemical substances, such as prostaglandins, that cause pain and swelling. Thus, it helps reduce inflammation (redness and swelling) in the intestines and provides relief from symptoms such as stomach pain or bleeding.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Pentasa 1 gm Suppository

Do not use Pentasa 1 gm Suppository in more doses or more often than prescribed. If you have any unusual signs or symptoms, please consult a doctor immediately.

Drug Warnings

  • Inform your doctor if you are allergic to this medication or any of its components.
  • The use of Pentasa 1 gm Suppository should be exercised with caution in the elderly.
  • Avoid taking Pentasa 1 gm Suppository if you have severe kidney failure.
  • Do not use Pentasa 1 gm Suppository if you are pregnant, planning to become pregnant, or breastfeeding without first consulting the doctor.
  • Pentasa 1 gm Suppository is recommended not to be used in populations with severe renal or hepatic impairment, so inform your doctor if you have severe renal or hepatic impairment.
  • Use Pentasa 1 gm Suppository as directed by a doctor, in the dose and duration advised.
  • Pentasa 1 gm Suppository is for rectal use. Do not swallow it. In case of accidental swallowing, drink plenty of water and consult a doctor immediately.
  • Pentasa 1 gm Suppository is not recommended for use in children.

Diet & Lifestyle Advise

  • Maintain a low-fat diet and eat foods rich in vitamin C, such as bell peppers, spinach, parsley, and berries, which help promote faster healing.
  • Opt for food and drinks rich in Omega-3 fatty acids to alleviate pain, swelling, and inflammation. Omega 3 fatty acid-enriched foods include flaxseeds, walnuts, soybean oil, salmon, and tuna if you prefer non-veg.
  • Eat more fibre-rich foods such as fruits and vegetables.
  • Eat smaller meals all day.
  • Drink small amounts of water throughout the day.
  • If you are intolerant to lactose, lower your intake of milk.
  • Avoid consuming foods high in sugar and fat, as well as processed foods, as these may trigger inflammation.
  • Try to avoid alcohol as it can affect your stomach and intestines and also limit the absorption of the important nutrients required by your body.

Habit Forming

No

Therapeutic Class

ANTI- INFLAMMATORY AGENTS

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Alcohol

Consult your doctor

The interaction of alcohol with Pentasa 1 gm Suppository is unknown. Consult the physician.

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Pregnancy

Unsafe

Pentasa 1 gm Suppository should not be used in pregnancy unless necessary. So, inform your doctor if you are pregnant or suspect pregnancy.

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Breast Feeding

Consult your doctor

Pentasa 1 gm Suppository should not be used while breastfeeding unless necessary. So, inform your doctor if you are a nursing mother. Your doctor will weigh the benefits and potential risks before prescribing Pentasa 1 gm Suppository.

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Driving

Safe if prescribed

Pentasa 1 gm Suppository usually does not affect your ability to drive or operate machinery.

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Liver

Consult your doctor

Inform your doctor before using Pentasa 1 gm Suppository if you have a history of liver disease. It should be used cautiously in patients with mild to moderately impaired liver function. It is not recommended for use in populations with severe liver impairment.

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Kidney

Caution

Inform your doctor before using Pentasa 1 gm Suppository if you have a history of kidney disease. It should be used cautiously in patients with mild to moderate kidney impairment. It is not recommended for use in populations with severe kidney impairment.

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Children

Not applicable

Pentasa 1 gm Suppository is intended for adults. Not recommended for children.

FAQs

Pentasa 1 gm Suppository is used to treat ulcerative colitis, a chronic inflammatory bowel disease that causes inflammation of the large intestine lining (colon).

Pentasa 1 gm Suppository contains Mesalazine, which works by inhibiting the production of certain chemical substances, such as prostaglandins, that cause pain and swelling. Thus, it helps reduce inflammation (swelling) in the intestines and relieves symptoms such as stomach pain or bleeding.

Pentasa 1 gm Suppository may cause diarrhoea as a common side effect. However, if the condition persists or worsens, accompanied by fever, watery stools, or persistent stomach pain, please consult a doctor. Also, drink plenty of water while using Pentasa 1 gm Suppository to prevent dehydration.

You are not recommended to take Pentasa 1 gm Suppository with aspirin as co-administration of these two medicines may increase the risk of kidney problems. However, please consult your doctor before taking Pentasa 1 gm Suppository with other medicines.

No, you are not recommended to stop using Pentasa 1 gm Suppository suddenly, as it may cause recurring symptoms. Therefore, use Pentasa 1 gm Suppository for as long as your doctor has prescribed it, and if you experience any difficulty while using Pentasa 1 gm Suppository, please consult your doctor.

Country of origin

INDIA

Manufacturer/Marketer address

K-28/1, ADDITIONAL MIDC , ANAND NAGAR , AMBERNATH - 421506 , INDIA
Other Info - PEN0413

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