Apollo
logo

Welcome User

Login/Sign Up

Home
Buy Medicines
Lab Tests
Doctor Consult
Circle Membership
insurance
Blogs
Contact Us
Privacy Policy
Return & Refunds
Need Help
Terms and Conditions
Select Delivery Location
compositionComposition:OXETACAINE-0.4%W/W+SUCRALFATE-7%W/W
prescription
Prescription Medicine
info
image icons

Pepsigard T Rectal Cream is used to treat haemorrhoids (piles). Hemorrhoids, known as piles, are inflamed and bulging veins that cause discomfort, pain and bleeding in the rectum and anus. It contains sucralfate and oxetacaine as key ingredients. It forms a protective layer over the damaged ulcer tissue in the stomach, shielding it from acid or injury. This protective barrier facilitates healing. It works by blocking nerve signals, providing fast relief from pain caused by ulcers. Its numbing effect offers immediate and prolonged pain relief.

Read more
Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
OffersOffers & Discounts

Get Free delivery (₹99) with circle icon

Join Circle
coupon
Get 18% Off with Coupons
coupon
Extra 10% Off with Bank Offers
bank offer
bank offer
bank offer

More about the Product

Composition :

OXETACAINE-0.4%W/W+SUCRALFATE-7%W/W

Manufacturer/Marketer :

Saf Fermion Ltd

Consume Type :

Topical

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Pepsigard T Rectal Cream

Pepsigard T Rectal Cream is a specialized oral liquid medication used to treat and manage painful conditions of the food pipe and stomach, such as stomach ulcers, acid reflux, and inflammation. It helps protect the sensitive lining of your digestive tract while quickly relieving localized pain. By acting directly where it is needed, it offers targeted comfort to irritated mucosal tissues.

For the best results, you should take this medicine consistently at the times prescribed by your doctor. It is typically taken on an empty stomach, either one hour before meals or two hours after eating, to allow the protective layer to form properly. Making simple dietary adjustments, such as eating smaller portions and avoiding highly seasoned or fatty foods, can greatly enhance your comfort and healing.

Most individuals tolerate this medication well, though mild side effects like constipation, diarrhea, or a dry sensation in the mouth can occur. If you experience severe stomach discomfort, persistent vomiting, or signs of an allergic reaction, stop taking it and contact your doctor immediately. Always consult a healthcare professional if you experience any unusual symptoms.

Talk to your doctor before starting this medicine if you have kidney problems, as your body may have difficulty processing some of the minerals in this suspension. Do not take this if you have a known allergy to any of the ingredients in Pepsigard T Rectal Cream. It is highly recommended to have a professional medical evaluation to confirm your diagnosis before beginning treatment.

This medication can interfere with how your body absorbs other pills, so it is important to space out your medicines carefully. You should also talk to your doctor or pharmacist if you are pregnant, breastfeeding, or are an older adult to ensure this is the safest treatment option for your specific situation.

Uses of Pepsigard T Rectal Cream

  • Stomach and intestinal ulcers: Pepsigard T Rectal Cream helps by creating a physical barrier over the open sore, shielding it from stomach acids and digestive enzymes so it can heal.
  • Acid reflux (GERD): Pepsigard T Rectal Cream relieves the burning sensation in your chest and throat by protecting the food pipe from backing-up stomach acid.
  • Esophagitis (inflammation of the food pipe): Pepsigard T Rectal Cream calms irritation, reduces swelling, and numbs local pain in the food pipe, making it easier to swallow.

 

Key Benefits

  • Fast-acting pain relief: Because this liquid contains a powerful local numbing agent, it works within minutes to soothe intense burning and pain in your chest or stomach.
  • Protective liquid shield: It behaves like a liquid bandage, covering raw and inflamed tissues in your gut. This prevents stomach acid from continuously irritating the area, allowing the tissue to recover.
  • Improved daily comfort: By reducing pain during and after meals, this medication helps you enjoy your food and go about your daily activities without constant digestive discomfort.
     

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safety.
  • Check the label for directions before using Pepsigard T Rectal Cream.
  • Take the required amount of Pepsigard T Rectal Cream and apply it to the rectal (anus) region.
  • Wash your hands thoroughly before and after use.

How Pepsigard T Rectal Cream Works

This medicine uses a dual-action approach to target stomach pain and inflammation directly at the source. It combines two active components that work topically on the lining of your digestive tract without needing to be absorbed into your bloodstream to be effective. The first component acts as a physical shield. When it enters the acidic environment of your stomach, it forms a sticky, gel-like barrier that selectively binds to damaged tissues and ulcers. This creates a protective layer that blocks stomach acid, pepsin, and bile from causing further irritation. The second component is a highly effective local anesthetic. It temporarily numbs the nerve endings in the lining of your food pipe and stomach, providing rapid relief from severe pain and burning. Together, these actions protect your digestive tract and give it the quiet environment it needs to heal naturally.
bannner image

Alcohol

Consult your doctor

It is unknown whether alcohol interacts with Pepsigard T Rectal Cream. However, avoid or limit alcohol as a precaution.

bannner image

Pregnancy

Consult your doctor

If you are pregnant or planning pregnancy, inform your doctor before applying Pepsigard T Rectal Cream. Your doctor may prescribe this medicine if the benefits outweigh the risks.

bannner image

Breast Feeding

Consult your doctor

Limited data is available on the effect of Pepsigard T Rectal Cream on breastfeeding. Hence, if you are a nursing mother, inform your doctor before receiving Pepsigard T Rectal Cream. Your doctor may prescribe this medicine if the benefits outweigh the risks.

bannner image

Driving

Consult your doctor

It is unknown whether Pepsigard T Rectal Cream affects driving ability. Hence, consult your doctor.

bannner image

Liver

Consult your doctor

Limited information is available on using Pepsigard T Rectal Cream in liver disease patients. Please consult your doctor if you have any concerns regarding using Pepsigard T Rectal Cream in patients with liver impairment.

bannner image

Kidney

Consult your doctor

Limited information is available on using Pepsigard T Rectal Cream in kidney disease patients. Please consult your doctor if you have any concerns regarding using Pepsigard T Rectal Cream in patients with liver impairment.

bannner image

Children

Consult your doctor

Limited information is available on the use of Pepsigard T Rectal Cream in paediatric patients. Please consult your doctor. Your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Heart

Caution

Pepsigard T Rectal Cream should be avoided in heart patients unless specifically recommended by a doctor. Even with minimal absorption, underlying cardiac conditions may heighten the risk of adverse effects or interactions.

bannner image

Geriatrics

Caution

Pepsigard T Rectal Cream should be avoided in geriatric patients unless prescribed by a doctor. Older adults may have thinner or more sensitive skin, increasing the risk of irritation or adverse reactions, so medical supervision is important.

What if I have taken an overdose of Pepsigard T Rectal Cream

If you accidentally take too much of this medicine and experience severe stomach pain, persistent vomiting, or extreme drowsiness, seek immediate medical attention or contact a poison control center right away.

Diet & Lifestyle Advise

  • Eat smaller, frequent meals: Consuming smaller portions helps prevent your stomach from stretching too much, which reduces acid production and pressure.
  • Avoid trigger foods: Stay away from spicy, greasy, acidic, or fried foods, as well as caffeine, chocolate, and carbonated drinks that can irritate your stomach lining.
  • Stay upright after eating: Do not lie down for at least 2 to 3 hours after a meal to prevent acid from flowing back up into your food pipe.
  • Elevate your head: Raise the head of your bed by 6 inches using blocks or a wedge pillow to help keep acid down while you sleep.
health query

Have a query?

How Soon It Starts Working

  • The time required for Pepsigard T Rectal Cream to start to work: Pepsigard T Rectal Cream ideally shows its action within 1 to 2 hours after application.
  • The time for which the effects of Pepsigard T Rectal Cream last: The duration of action for Pepsigard T Rectal Cream is clinically unknown.

What if you forget to take Pepsigard T Rectal Cream

If you miss a dose, take it as soon as you remember, provided it is on an empty stomach. However, if it is almost time for your next dose, skip the missed one and return to your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store in a cool and dry place away from sunlight.• Keep Pepsigard T Rectal Cream out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Always shake the bottle vigorously before pouring your dose to ensure the active ingredients are evenly distributed.
  • Do not eat or drink anything for at least 15 to 30 minutes after taking your dose so the protective barrier can form properly on your stomach lining.
  • Space out other medications by at least 2 hours before or after taking Pepsigard T Rectal Cream, as it can significantly reduce the absorption of other pills.
  • Inspect the liquid before use; do not take it if you notice unusual clumping, discoloration, or a strange odor.

verifiedApollotooltip
  • Antibiotics (such as tetracyclines and fluoroquinolones): Pepsigard T Rectal Cream can bind to these drugs in your stomach, making them much less effective. Take your antibiotics at least 2 hours before or 4 to 6 hours after this medication.
  • Thyroid hormones (levothyroxine): Taking these medications together can reduce the absorption of your thyroid medicine. Space them at least 4 hours apart.
  • Heart medications (digoxin, quinidine): This suspension can decrease the amount of heart medicine absorbed by your body, reducing its therapeutic effect.

Login/Sign Up

verifiedApollotooltip
  • Food: Taking this medication with or immediately after a meal prevents the protective coating from sticking to the lining of your stomach and ulcers, making the medicine less effective.
     

Login/Sign Up

All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[MISCELLANEOUS]

FAQs

Pepsigard T Rectal Cream is used to treat Hemorrhoids.
Pepsigard T Rectal Cream strengthens the walls of tiny blood vessels and prevents leakage and fragility. It relieves the symptoms of haemorrhoids (piles).
Continue using Pepsigard T Rectal Cream for as long as your doctor has prescribed it to treat your illness effectively. Consult your doctor if you experience any undesirable effects during the treatment with Pepsigard T Rectal Cream.
The local numbing component in Pepsigard T Rectal Cream usually starts relieving pain within a few minutes of taking it, while the protective coating begins working almost immediately. If your symptoms do not improve after a few days, talk to your doctor.
This medicine can block the absorption of many other drugs. You should take other medications at least 2 hours before or after taking Pepsigard T Rectal Cream. Talk to your doctor or pharmacist to set up a safe schedule for all your medicines.
The safety of this medication during pregnancy has not been fully established. Since some components can be absorbed in tiny amounts, you should talk to your doctor to weigh the benefits against any risks before using it.
Yes, constipation is one of the most common side effects of this medication because it contains minerals that can slow down bowel movements. Drinking plenty of water and eating fiber-rich foods can help, but always talk to your doctor if the constipation is severe.
No, you do not need to refrigerate Pepsigard T Rectal Cream. Store it at room temperature, away from direct light and heat, and make sure it does not freeze. Talk to your pharmacist if you need more storage advice.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. DrugBank Online. Db12532 Clinical & Chemical Summary. Edmonton, AB: DrugBank; 2026. [Accessed on 02 Jun. 2026]Check here
  2. National Center for Biotechnology Information (NCBI). Sucralfate + Oxetacaine Scientific Research Publication. Bethesda, MD: NLM; 2025. [Accessed on 02 Jun. 2026]Check here
  3. National Center for Biotechnology Information (NCBI). Pmc7975930 Scientific Research Publication. Bethesda, MD: NLM; 2025. [Accessed on 02 Jun. 2026]Check here
  4. Sucralfate Sucralfate. 2013. [Accessed on 15 Apr. 2019]Check here
  5. Pujitha Kudaravalli; Savio John. Sucralfate. StatPearls [Internet]. NIH. National Library of Medicine. National Center for Biotechnology Information. [Revised in February 2022]. [Accessed on 15th October 2022]Check here
  6. Oxetacaine. [Accessed on 02 Jun. 2026]Check here
  7. Iwj.13901. [Accessed on 02 Jun. 2026]Check here

Country of origin

India
Other Info - PE87097
whatsapp Floating Button
Buy Now
Add to Cart