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compositionComposition:ONDANSETRON-8MG
prescription
Prescription Medicine
info
Periset-8 Tablet 10's
Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

ONDANSETRON-8MG

Manufacturer/Marketer :

Alka Pharmaceuticals

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

NPPA :

Regulated

About Periset-8 Tablet

Periset-8 Tablet is a medication prescribed to prevent and treat nausea and vomiting. It is primarily used to help patients managing stomach upset caused by cancer chemotherapy, radiation therapy, or surgical procedures. This medicine helps manage these challenging symptoms so you can focus on your recovery.

Your doctor will determine how often you should take this medicine, which is typically taken consistently before your medical treatment begins. It can be taken safely with or without food. To get the best results, you can combine this treatment with simple lifestyle adjustments, such as eating small, frequent meals and keeping hydrated with clear liquids throughout the day.

While taking Periset-8 Tablet , some people may experience mild and temporary side effects such as headaches, constipation, or a warm, flushed feeling. While these are common and usually resolve on their own, you must consult your doctor immediately if you experience severe side effects, such as a rapid or irregular heartbeat, severe dizziness, or fainting.

Before starting this medication, talk to your doctor if you have a history of liver damage, heart rhythm conditions, or imbalances of potassium or magnesium in your blood. Do not take this if you are currently taking apomorphine, as the combination can cause a dangerous drop in blood pressure.

This medicine can interact with other substances, including certain antidepressants, which can lead to serious nervous system complications. It is also important to limit alcohol, as it can worsen dizziness and stomach upset. If you are pregnant, breastfeeding, or an elderly individual, consult your doctor or pharmacist to ensure this treatment is safe for your specific situation.

Uses of Periset-8 Tablet

Periset-8 Tablet may be prescribed for the following conditions: 

  • Chemotherapy-induced nausea and vomiting: This medicine helps prevent and manage severe stomach upset and vomiting triggered by cancer chemotherapy treatments.
  • Radiation therapy-induced nausea and vomiting: It is used to control nausea in patients undergoing radiation therapy, particularly treatments directed at the abdomen.
  • Post-operative nausea and vomiting: It prevents and treats the nausea and vomiting that commonly occur in patients waking up from anaesthesia after surgery.

Key Benefits

Periset-8 Tablet helps prevent and control nausea and vomiting caused by medical treatments, surgery, or other conditions. It works by blocking signals that trigger the urge to vomit, helping improve comfort and recovery.

  • Prevents Nausea and Vomiting: Helps control nausea and vomiting associated with chemotherapy, radiotherapy, surgery, and other medical conditions.
  • Provides Rapid Symptom Relief: Acts quickly to reduce feelings of nausea and prevent vomiting episodes.
  • Supports Treatment Adherence: Helps patients continue important treatments, such as chemotherapy and radiation therapy, more comfortably.
  • Reduces the Risk of Dehydration: By preventing vomiting, it helps the body retain fluids, nutrients, and prescribed medicines.
  • Promotes Recovery and Comfort: Helps improve overall well-being and supports a smoother recovery after surgery or illness.
Side effects of Periset-8 Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Get enough sleep. Maintain a regular sleep cycle.
  • Eat a healthy diet and exercise regularly.
  • Manage stress with yoga or meditation.
  • Limit alcohol and caffeine.
  • Avoid driving or operating machinery unless you are alert.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
  • Avoid rubbing or scratching the affected area, as this can cause further irritation and discomfort.
  • Consider using a humidifier to add moisture to the air and help reduce the sensation.
  • Seek medical attention if the sensation is severe, persistent, or worsens over time.
  • Avoid extreme temperatures, such as hot or cold showers, that can exacerbate the sensation.
  • Wear light, breathable clothing to help keep the body cool and reduce the sensation.
  • Avoid triggers that can cause the sensation, such as spicy foods or hot drinks.
  • Use cool compresses or fans to help lower body temperature and reduce the sensation.
Managing Medication-Triggered malaise (Feeling Unwell): A Step-by-Step Guide:
  • If you experience persistent or severe malaise (a general feeling of discomfort, illness, or unease) after taking medication, seek medical attention immediately.
  • Inform your doctor about the medication you're taking and the symptoms you're experiencing.
  • Your treatment plan may be modified, which may include adjusting the dosage, substituting with an alternative medication, or discontinuing the medication. Additionally, certain lifestyle changes may be recommended to help manage symptoms.
  • To manage malaise symptoms, follow your doctor's advice, such as getting plenty of rest, staying hydrated, and practicing stress-reducing techniques.
  • Track your symptoms regularly and report any changes or concerns to your healthcare provider to ensure the malaise is managed effectively.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.

Directions for Use

To ensure the medicine works effectively, follow these step-by-step instructions based on your specific oral dosage form:

  • If you are taking regular swallowable tablets, swallow the tablet whole with a full glass of water. You can take it with or without food. Do not crush or chew the tablet.
  • If you are taking disintegrating tablets, ensure your hands are completely dry. Gently peel back the foil backing of the blister pack rather than pushing the tablet through, as the tablet is delicate and can break. Place the tablet directly on your tongue, allow it to dissolve completely, and swallow it with your saliva. You do not need to drink water to take this form.

Always follow your doctor's exact instructions regarding your specific schedule and when to take your dose relative to your treatments.

How Periset-8 Tablet Works

This medicine contains ondansetron, which works by blocking serotonin, a natural chemical in your body that triggers the vomiting reflex. When you undergo chemotherapy, radiation, or surgery, your body releases large amounts of serotonin, which binds to specific receptors in your gut and brain to signal your stomach to vomit. By blocking these specific serotonin receptors, Periset-8 Tablet prevents those chemical signals from reaching the vomiting centre in your brain. This stops the sensation of nausea before it can escalate, giving you effective and reliable control over your symptoms.
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Alcohol

Caution

Alcohol has no known direct interaction with Periset-8 Tablet . However, it is advisable to avoid consuming alcohol while taking Periset-8 Tablet , as it may worsen the side effects like drowsiness.

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Pregnancy

Unsafe

Periset-8 Tablet should be used during pregnancy only if prescribed by a doctor. It is generally not recommended for use during early pregnancy (first trimester), as it may increase the risk of birth defects in the mouth and face of the baby.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Periset-8 Tablet , as small amounts of the medicine may pass into breast milk.

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Driving

Caution

Periset-8 Tablet does not affect your ability to drive. However, if you experience drowsiness or blurred vision after taking Periset-8 Tablet , avoid driving or operating any heavy machinery.

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Liver

Caution

In individuals with liver problems, the use of Periset-8 Tablet is allowed if prescribed by a doctor. However, patients with severe liver impairment should take a low dose of Periset-8 Tablet as much as possible. Do not take more than 8 mg of Periset-8 Tablet per day in case of liver disease.

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Kidney

Safe if prescribed

The use of Periset-8 Tablet is considered safe in patients with kidney disorders. No dose adjustment is required.

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Children

Safe if prescribed

Periset-8 Tablet should not be given to children below 4 years of age, as its safety and effectiveness have not been established in this age group. The use of Periset-8 Tablet is safe in children above 4 years of age if prescribed by a doctor.

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Heart

Caution

Periset-8 Tablet should be taken with caution in patients with heart problems. Please inform your doctor if you have any pre-existing heart problems before using Periset-8 Tablet .

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Geriatrics

Caution

Periset-8 Tablet should be given with caution in elderly patients due to an increased risk of side effects. Seek medical advice before using Periset-8 Tablet .

What if I have taken an overdose of Periset-8 Tablet

Do not take more than the prescribed dose of Periset-8 Tablet , as it may lead to an overdose. Symptoms of an overdose may include sudden loss of vision for a short time, irregular heartbeat, constipation, fainting, dizziness, or light-headedness. If you suspect that you have taken an overdose of this medication or notice any unusual symptoms, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Stay hydrated gradually: Avoid drinking large amounts of liquid all at once. Instead, sip small amounts of water, clear broths, or electrolyte drinks continuously throughout the day.
  • Eat small, frequent meals: Rather than eating three large meals, eat five or six small portions of bland, low-fat foods. Excellent choices include crackers, toast, plain rice, oatmeal, and applesauce.
  • Avoid strong odours: Keep your eating and resting areas well-ventilated. Cooking smells, heavy perfumes, and household chemicals can quickly trigger nausea.
  • Remain upright after eating: Sit up or rest in a comfortable, upright position for at least 30 to 60 minutes after meals to help digestion and prevent acid reflux.

Have a query?

How Soon It Starts Working

  • The time required for Periset-8 Tablet to start to work: Periset-8 Tablet ideally shows its action within 2 hours after administration.
  • The time for which the effects of Periset-8 Tablet last: The effect of Periset-8 Tablet lasts for 12 to 28 hours.

What if you forget to take Periset-8 Tablet

If you forget to take a dose of Periset-8 Tablet , take it as soon as you remember. However, if it is time for your next dose, skip the missed dose and take your regular dose. Never take a double dose to make up for a forgotten dose.

Storage

• Store the tablets at room temperature, ideally between 68°F and 77°F (20°C and 25°C). • Keep your medication in a dry place away from direct light and moisture. Do not store this medicine in bathroom cabinets, as high humidity can damage the tablets.

Drug Warnings

  • Check the Dosage Form: Confirm whether you have regular tablets or orally disintegrating tablets, as they should be taken differently.
  • Handle Disintegrating Tablets Carefully: Peel back the foil gently with dry hands and avoid pushing orally disintegrating tablets through the packaging.
  • Use Caution During Activities: Avoid driving or operating machinery if Periset-8 Tablet causes dizziness, drowsiness, or reduced alertness.
  • Manage Constipation: Speak with your doctor or pharmacist about ways to prevent or manage constipation, which can occur during treatment.
  • Inform Healthcare Providers About Other Medicines: Tell your doctor about all medicines, vitamins, and herbal supplements you are taking before starting Periset-8 Tablet .

Drug-Drug Interactions

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Drug-Drug Interactions

Inform your doctor if you are taking any of the following medicines, as they may interact with Periset-8 Tablet : 

  • Apomorphine: Do not take this medicine if you are using apomorphine (a drug used for Parkinson's disease). Combining them can cause an extreme, dangerous drop in blood pressure and loss of consciousness.
  • Antidepressants (SSRIs and SNRIs): Taking Periset-8 Tablet alongside certain antidepressants can increase the risk of serotonin syndrome, a rare but life-threatening condition that causes high fever, agitation, and muscle stiffness.
  • Heart rhythm medications: Combining this medicine with drugs that alter your heart's electrical activity can increase the risk of irregular heartbeats.


Drug-Food Interactions

The following food or drink may affect your treatment with Periset-8 Tablet : 

  • Alcohol: Avoid drinking alcohol while taking this medicine. Alcohol can significantly worsen side effects like drowsiness and dizziness, and it can further irritate your stomach.


Drug-Disease Interactions

Inform your doctor if you have any of the following conditions before taking Periset-8 Tablet : 

  • Liver damage: If you have severe liver damage, your body may process this medicine much slower than normal. Your doctor may need to prescribe a lower daily dose.
  • Heart conditions: If you have a history of long QT syndrome, heart failure, or irregular heartbeats, use this medicine with extreme caution, as it can affect your heart's electrical rhythm.
  • Electrolyte imbalances: Having low blood levels of potassium or magnesium increases your risk of developing heart rhythm complications while taking this medicine.
OndansetronZiprasidone
Critical
OndansetronLinezolid
Severe

Drug-Drug Interactions

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OndansetronZiprasidone
Critical
How does the drug interact with Periset-8 Tablet:
Taking Periset-8 Tablet with Ziprasidone can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Periset-8 Tablet with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
OndansetronLinezolid
Severe
How does the drug interact with Periset-8 Tablet:
When Periset-8 Tablet is taken with linezolid it can cause serotonin syndrome. (a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Co-administration of Periset-8 Tablet along with linezolid can lead to an interaction, it can be taken if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, incoordination, stomach pain, nausea, vomiting, and diarrhea, consult the doctor. Do not discontinue any medications without consulting a doctor.
OndansetronAlmotriptan
Severe
How does the drug interact with Periset-8 Tablet:
When Periset-8 Tablet, is taken with almotriptan it can cause serotonin syndrome (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Periset-8 Tablet along with almotriptan can lead to an interaction, it can be taken if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, a shaking sensation, incoordination, stomach cramp, nausea, vomiting, and diarrhea, see a doctor. Do not discontinue any medications without a doctor's advice.
OndansetronFentanyl
Severe
How does the drug interact with Periset-8 Tablet:
Taking fentanyl with Periset-8 Tablet may increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although taking fentanyl with Periset-8 Tablet can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience confusion, hallucinations (seeing and hearing things that do not exist), increased heart rate, fever, excessive sweating, muscle pain or stiffness, stomach cramps, vomiting, or diarrhoea, consult a doctor. Do not discontinue any medications without consulting your doctor.
OndansetronPanobinostat
Severe
How does the drug interact with Periset-8 Tablet:
Taking Periset-8 Tablet with Panobinostat increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Co-administration of Periset-8 Tablet along with Panobinostat can result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without a doctor's advice.
OndansetronRizatriptan
Severe
How does the drug interact with Periset-8 Tablet:
When Periset-8 Tablet, is taken with rizatriptan it increases the risk of serotonin syndrome (a condition in which a chemical called serotonin increase in body).

How to manage the interaction:
Although there is a possible interaction between Periset-8 Tablet and Rizatriptan, it can be taken if a doctor has advised it. If you notice any of these symptoms like confusion, hallucination, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, shaking of hands and legs, incoordination, stomach cramps, nausea, vomiting, and loose stools, contact a doctor. Do not discontinue any medications without consulting a doctor.
OndansetronTranylcypromine
Severe
How does the drug interact with Periset-8 Tablet:
When Periset-8 Tablet, is taken with tranylcypromine it increases the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in body).

How to manage the interaction:
Although taking Periset-8 Tablet along with tranylcypromine can lead to an interaction, it can be taken if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, a shaking sensation, incoordination, stomach cramp, nausea, vomiting, and diarrhea, see a doctor. Do not discontinue any medications without a doctor's advice.
OndansetronMifepristone
Severe
How does the drug interact with Periset-8 Tablet:
Co-administration of Periset-8 Tablet with mifepristone can increase the risk of irregular heart rhythms.

How to manage the interaction:
Taking Periset-8 Tablet with mifepristone together can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not discontinue any medications without consulting a doctor.
OndansetronMilnacipran
Severe
How does the drug interact with Periset-8 Tablet:
When Periset-8 Tablet, is taken with milnacipran it can cause serotonin syndrome. (a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Co-administration of Periset-8 Tablet along with milnacipran can lead to an interaction, it can be taken if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, a shaking sensation, incoordination, stomach cramp, nausea, vomiting, and diarrhea, see a doctor. Do not discontinue any medications without a doctor's advice.
OndansetronImipramine
Severe
How does the drug interact with Periset-8 Tablet:
Coadministration of Periset-8 Tablet along with imipramine can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Taking Periset-8 Tablet along with imipramine together can result in an interaction, it can be taken if a doctor has advised it. However, if you have sudden dizziness, lightheadedness, fainting, confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles, or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea, or fast or rapid heartbeats during therapy, consult the doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIEMETICS]

FAQs

Periset-8 Tablet is used in the prevention of vomiting and nausea that usually occur after cancer chemotherapy, radiation treatment, or surgery.

Periset-8 Tablet contains Ondansetron, which works by blocking the action of a chemical in the body (serotonin) responsible for causing nausea and vomiting.

Periset-8 Tablet may cause drowsiness and changes in vision, so avoid driving or operating any machines that require mental alertness.

People with an irregular heartbeat (arrhythmia) and phenylketonuria (too much of the protein phenylalanine in the blood) should not take Periset-8 Tablet as it may cause serious conditions. The patient with liver disease should not take more than 8 mg of Periset-8 Tablet daily. Taking Periset-8 Tablet with apomorphine can cause a sharp dip in blood pressure, even leading to death, so avoid its intake together.

Periset-8 Tablet contains Ondansetron, an antiemetic drug, used in the prevention of vomiting and nausea.

Before taking Periset-8 Tablet , inform your doctor about all your medical conditions, sensitivities, and medications you are using. Also, tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Common side effects of Periset-8 Tablet may include constipation, headache, diarrhea, drowsiness, flushing (a feeling of warmth), weakness, and tiredness. However, not every person experiences these side effects, and some of the unpleasant effects of Periset-8 Tablet do not require medical attention. If the side effects persist or worsen, please consult your doctor.

Periset-8 Tablet works by blocking the action of a chemical in the body (serotonin) that is responsible for causing nausea and vomiting. As a result, Periset-8 Tablet prevents the sensation of nausea and vomiting caused by conditions like surgery, cancer chemotherapy, pregnancy, or motion sickness.

Yes, you can take Periset-8 Tablet half an hour to 1 hour before meals.

If you forget to take a dose of Periset-8 Tablet , take it as soon as you remember. However, if it is time for your next dose, skip the missed dose and take your regular dose. Never take a double dose to make up for a forgotten dose.

If you take more than the recommended dose of Periset-8 Tablet , it may result in an overdose. Signs and symptoms of an overdose of Periset-8 Tablet may include constipation, dizziness or lightheadedness, fainting, irregular heartbeat, and sudden loss of vision for a short time. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

No, Periset-8 Tablet is not a steroid. Periset-8 Tablet belongs to a class of drugs known as antiemetics.

While specific dosing instructions will vary depending on your individual needs and medical history. Always follow your doctor's prescribed dosage and timing for taking these medications.

Take Periset-8 Tablet exactly as prescribed by the doctor. Take it at the same time daily, as it will help you remember to take the medication.

Yes, Periset-8 Tablet can be given during pregnancy if prescribed by a doctor. However, it is not recommended for use during early pregnancy (first trimester), as it may increase the risk of birth defects in the mouth and face of the baby.

Yes, you can take this medicine with or without food. If you find that taking it on an empty stomach makes you feel slightly uneasy, try taking your dose with a small snack or a light meal. Talk to your doctor or pharmacist if your nausea makes it difficult to eat.

This medicine generally starts working within 1 to 2 hours after you take it. If you are taking the orally disintegrating tablet, it dissolves rapidly on your tongue and begins absorbing quickly to help keep your symptoms controlled. Talk to your doctor if your nausea does not improve after taking it.

Feeling tired or drowsy is a known, common side effect of this medicine. If you experience drowsiness, lightheadedness, or dizziness, avoid driving, riding a bicycle, or operating tools and machinery. Talk to your doctor if this sleepiness interferes with your daily routine.

You must consult your doctor before using this medicine during pregnancy. While it is sometimes prescribed for severe pregnancy-related nausea, your doctor will carefully evaluate your situation to ensure it is the safest option for both you and your developing baby. Talk to your doctor for personalised advice.

It is highly recommended to avoid alcohol while taking this medicine. Alcohol can worsen side effects like drowsiness, headache, and dizziness, and it can also irritate your stomach lining, which may make your nausea worse. Talk to your doctor if you have questions about alcohol use.

If you vomit shortly after taking your dose, do not take an immediate replacement dose, as you may accidentally absorb too much medicine. Contact your doctor or pharmacist right away for specific, safe instructions on whether to take another dose or wait.

This medicine is generally not effective for motion sickness. It targets chemical pathways in the body associated with chemotherapy, radiation, and surgery rather than the balance centres in the inner ear. Talk to your doctor or pharmacist to find a more appropriate treatment for travel-related nausea.

You should only take this medicine for the exact duration prescribed by your doctor. The duration of treatment depends on the condition being treated and your doctor's recommendation. Some people may use Periset-8 Tablet for a short period around chemotherapy, surgery, or radiation therapy, while others may require treatment for longer. Talk to your doctor if your nausea persists beyond your prescribed treatment days.

Disclaimer

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Reference

  1. U.S. Food and Drug Administration (FDA). 020103S035 020605S019 020781S019Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026] Check here
  2. Electronic Medicines Compendium (EMC). Product Summary of Product Characteristics (SmPC). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026] Check here
  3. Drugs.com Clinical Review Team. Ondansetron Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026] Check here
  4. MedlinePlus. A601209 Patient Information Monograph. Bethesda, MD: U.S. National Library of Medicine (NLM); 2025. [Accessed on 02 Jun. 2026] Check here
  5. Ondansetron 4 mg film-coated tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2025 [Accessed on 17th September 2025] Check here
  6. Ondansetron 4 mg film-coated tablets - Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2025 [Accessed on 17th September 2025] Check here
  7. CDSCO [Internet]. Cdscoonline.gov.in. 2025 [Accessed on 17th September 2025]Check here

Country of origin

India

Manufacturer/Marketer address

142 AB, Kandivli Industrial Estate, Kandivli (West), Mumbai - 400 067, Maharashtra
Other Info - PER0108

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