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  3. Pezlor-1 Tablet 10's

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Pezlor-1 Tablet 10's, Pack of 10 TABLETS
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Pezlor-1 Tablet 10's is used to treat epilepsy (status epilepticus) and anxiety disorder. It may be prescribed as short-term therapy for sleeping difficulties due to anxiety. It may also be used as a sedative prior to surgery. It contains Lorazepam, which works by increasing levels of the calming chemical in the brain; this helps relieve anxiety, stops seizure attacks (fits) and relaxes the tense muscles. It may cause common side effects such as sleepiness, tiredness, muscle weakness and problems with coordination. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

LORAZEPAM-1MG

Manufacturer/Marketer :

Signova Pharma

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Pezlor-1 Tablet 10's

Pezlor-1 Tablet 10's is used to treat epilepsy (status epilepticus) and anxiety disorder. Pezlor-1 Tablet 10's may be prescribed as short-term therapy for sleeping difficulties due to anxiety. It may also be used as a sedative prior to surgery. An anxiety disorder is a mental health disorder characterised by feelings of excessive fear or worry that affect an individual's daily activities. Epilepsy is a chronic disorder characterised by episodes of seizures (fits). 

Pezlor-1 Tablet 10's contains lorazepam, which works by increasing levels of the calming chemical mediator known as gamma-aminobutyric acid (GABA) in the brain; this helps relieve anxiety, stops seizure attacks (fits) and relaxes the tense muscles.

Take Pezlor-1 Tablet 10's exactly as prescribed. The common side effects of Pezlor-1 Tablet 10's are sleepiness, tiredness, muscle weakness and problems with coordination. Most of these side effects of Pezlor-1 Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Do not take Pezlor-1 Tablet 10's if you are allergic to any of its components. Inform your doctor if you have lung disease, muscle weakness (myasthenia gravis), sleeping disorder, severe liver disease, or problems with alcohol or other recreational drugs. Pezlor-1 Tablet 10's is a habit-forming drug, and hence, there is a risk of dependence on this medicine. Before stopping this medicine, contact a doctor as it may cause withdrawal symptoms like anxiety, increased heart rate, tremors or general unwell feeling.

Uses of Pezlor-1 Tablet 10's

Pezlor-1 Tablet 10's is used in the treatment of epilepsy (fits) and anxiety disorders. The detailed uses of Pezlor-1 Tablet 10's are as follows:

  • Anxiety management: Pezlor-1 Tablet 10's is frequently prescribed for short-term relief of anxiety symptoms, promoting calmness and alleviating intense feelings of worry or panic.
  • Sedation: Pezlor-1 Tablet 10's serves as a sedative before medical procedures or surgeries, calming patients and reducing anxiety.
  • Insomnia treatment: Pezlor-1 Tablet 10's plays a role in treating anxiety-related insomnia by assisting individuals in falling asleep through stress and anxiety reduction.
  • Seizure control: Pezlor-1 Tablet 10's is employed in treating certain seizure disorders by stabilising patients experiencing acute seizures.
  • Alcohol withdrawal symptoms: Pezlor-1 Tablet 10's reduces symptoms of alcohol withdrawal, easing the transition for those reducing or stopping alcohol intake.

Directions for Use

• Pezlor-1 Tablet 10's can be taken with or without food as advised by your doctor. • Follow your doctor's instructions on the dosage and timing of this medication. • Swallow Pezlor-1 Tablet 10's as a whole with a glass of water. • Do not crush, break, or chew it.

Medicinal Benefits

Pezlor-1 Tablet 10's belongs to a group of medications called benzodiazepine, primarily used to treat epilepsy (fits) and anxiety disorder. Pezlor-1 Tablet 10's contains lorazepam, which works by increasing levels of the chemical mediator that calms brain cells (neurons), known as gamma-aminobutyric acid (GABA); this helps relieve anxiety, stops seizure attacks (fits) and relaxes tense muscles. Additionally, Pezlor-1 Tablet 10's may be prescribed as short-term therapy for sleeping difficulties due to anxiety. It may also be used as a sedative prior to surgery.

How Pezlor-1 Tablet 10's Works

Pezlor-1 Tablet 10's contains lorazepam, which works by increasing levels of the calming chemical mediator known as gamma-aminobutyric acid (GABA) in the brain; this helps relieve anxiety, stops seizure attacks (fits) and relaxes the tense muscles.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Pezlor-1 Tablet
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
  • Apply a hot/cold pack to the affected area.
  • Doing gentle exercises can help cope with pain by stretching muscles.
  • Get enough sleep. It helps enhance mood and lower pain sensitivity.
  • Avoid alcohol, smoking and tobacco as they can increase pain.
  • Follow a well-balanced meal.
  • Meditation and massages may also help with pain.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Stay organized with calendars, planners, and sticky notes. Write in notebooks and journals to remember things. Make photo albums to trigger memories and track special events.
  • Use digital tools to help you remember like reminder apps, voice recordings, and GPS navigation
  • Improve your memory with brain exercises, memory aids, and visualization.
  • Create a daily routine and set a schedule. Use reminders and labels to stay organized and on track.
  • Get help to recall from family and friends. You can also talk to a therapist for support.
  • Confusion is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control confusion.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your confusion.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes.
  • Talk to your dietician and consume food that can improve your mental health.
Managing depression as a side effect of medication: a comprehensive guide.
  • Remember, managing depression as a side effect of medication requires patience, persistence, and collaboration with your healthcare team.
  • Tell your doctor about your depression symptoms to adjust medication.
  • Consult a therapist or counsel for emotional support.
  • Engage in regular exercise to release endorphins (neurotransmitters).
  • Practice stress-reducing techniques like meditation and deep breathing.
  • Build a support network of friends, family, and support groups.
  • Establish a consistent sleep schedule.
  • Eat a nutritious diet rich in fruits, vegetables, and whole grains.
  • Limit or avoid alcohol and recreational substances.
  • Keep a mood journal to track symptoms and progress.

What if I have taken an overdose of Pezlor-1 Tablet 10's

Do not take more than the prescribed dose of Pezlor-1 Tablet 10's as it may cause overdose. The symptoms of overdose include sleepiness, slow or irregular heartbeat, uncontrolled eye movements, muscle weakness, overexcited, trouble speaking or poor coordination. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Inform your doctor if you have had severe breathing problems, are allergic to lorazepam or other related benzodiazepines, have muscle weakness (myasthenia gravis), serious liver problems, breathing problems, or glaucoma (high blood pressure in eyes), are breastfeeding, pregnant or planning for pregnancy. Avoid using Pezlor-1 Tablet 10's with opioid medicines as it can cause severe drowsiness, breathing problems, coma, and death. Pezlor-1 Tablet 10's should be taken with extreme caution in patients with a history of alcohol or drug abuse. If you feel suicidal thoughts, difficulty in concentration, sleep disturbances, dizziness, or sleepiness, let your doctor know about this.

Drug-Drug Interactions

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LorazepamTapentadol
Severe
LorazepamAlfentanil
Severe

Drug-Drug Interactions

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LorazepamTapentadol
Severe
How does the drug interact with Pezlor-1 Tablet:
Using Pezlor-1 Tablet together with Tapentadol can increase the risk or severity of side effects like decreased breathing rate, irregular heart rhythms, or problems with movement and memory.

How to manage the interaction:
Taking Pezlor-1 Tablet with Tapentadol is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of dizziness, lightheadedness, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
LorazepamAlfentanil
Severe
How does the drug interact with Pezlor-1 Tablet:
Using narcotic pain or cough medications together with other medications that also cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
There may be a possibility of interaction between Pezlor-1 Tablet and Alfentanil, but it can be taken if prescribed by a doctor. It's important to keep an eye on your health. Your doctor can recommend other options that won't cause any problems. If you notice any of these signs - feeling sad, having trouble breathing, feeling dizzy or sleepy, or finding it hard to focus - make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.
LorazepamMorphine
Severe
How does the drug interact with Pezlor-1 Tablet:
Using Pezlor-1 Tablet together with Morphine can increase the risk of central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Co-administration of Morphine with Pezlor-1 Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms like trouble breathing, feeling tired, or having a cough, dizziness, drowsiness, difficulty concentrating, impaired judgment, reaction speed, and motor coordination, make sure to contact a doctor immediately. Do not stop using any medications without consulting a doctor.
LorazepamCaptopril
Severe
How does the drug interact with Pezlor-1 Tablet:
Coadministration of Pezlor-1 Tablet with Captopril may show additive effects and result in low blood pressure.

How to manage the interaction:
Although taking Pezlor-1 Tablet with Captopril together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice headache, dizziness, lightheadedness, fainting, or irregular pulse or heart rate, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
LorazepamTramadol
Severe
How does the drug interact with Pezlor-1 Tablet:
Coadministration of Pezlor-1 Tablet with Tramadol can increase the risk and severity of side effects like dizziness, decreased breathing rate, and irregular heart rates.

How to manage the interaction:
Taking Pezlor-1 Tablet with Tramadol together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of dizziness, lightheadedness, severe headache, weakness, difficulty concentrating, or impairment in judgment, and motor coordination you should contact a doctor immediately. Avoid driving or using hazardous machines. Do not stop using any medications without talking to a doctor.
LorazepamKetamine
Severe
How does the drug interact with Pezlor-1 Tablet:
Using Pezlor-1 Tablet together with Ketamine can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness, possibly leading to coma or death).

How to manage the interaction:
There may be a possibility of interaction between Ketamine and Pezlor-1 Tablet, but it can be taken if prescribed by a doctor. If you feel dizzy, sleepy, confused, have trouble focusing, feel too relaxed, or have trouble breathing, make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
LorazepamRemifentanil
Severe
How does the drug interact with Pezlor-1 Tablet:
Using Pezlor-1 Tablet together with Remifentanil can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness, possibly leading to coma or death).

How to manage the interaction:
Taking Pezlor-1 Tablet with Remifentanil together can result in an interaction, but it can be taken if your doctor has advised it. It's important to keep an eye on your health and talk to a doctor about any concerns. They can recommend different options that won't cause any problems. If you notice any discomfort like pain, feeling dizzy, or having trouble focusing, make sure to reach out to a doctor right away. Do not stop using any medications without talking to a doctor.
LorazepamDroperidol
Severe
How does the drug interact with Pezlor-1 Tablet:
Coadministration of Pezlor-1 Tablet with Droperidol can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Pezlor-1 Tablet and Droperidol, you can take these medicines together if prescribed by your doctor. If you notice that your heart is beating very slowly, your blood pressure is low, or your heart rhythm feels irregular, it's important to contact a doctor right away. Also, if you suddenly feel dizzy, lightheaded, or faint, or if your heartbeat doesn't feel normal, don't hesitate to reach out to a doctor for help. Do not stop using any medications without talking to a doctor.
LorazepamClozapine
Severe
How does the drug interact with Pezlor-1 Tablet:
Co-administration of Pezlor-1 Tablet with Clozapine may show additive effects and increase the risk or severity of side effects.

How to manage the interaction:
Although taking Pezlor-1 Tablet with Clozapine together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any extreme drowsiness, confusion, shallow breathing, low blood pressure, weak pulse, and incoordination, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
LorazepamEsketamine
Severe
How does the drug interact with Pezlor-1 Tablet:
Using Esketamine together with Pezlor-1 Tablet may increase side effects such as drowsiness, confusion, difficulty concentrating, and impairment in thinking, judgment, reaction speed, and motor coordination.

How to manage the interaction:
Although taking Pezlor-1 Tablet and Esketamine together can cause an interaction, it can be taken if your doctor has suggested it. If you're having trouble with feeling sleepy, confused or finding it hard to focus, it's important to let a doctor know right away. They may have other options for you that won't cause these problems. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Do regular exercise, this can help lower anxiety by releasing endorphins and improving your sleep and self-image.
  • You can increase your mindfulness by including yoga, meditation, mindfulness-based cognitive therapy and mindfulness-based stress reduction.
  • Drink enough water to stay hydrated.
  • Include a diet rich in whole grains, vegetables and fruits.
  • Herbs like turmeric, ginger and chamomile contain anti-inflammatory properties. They can reduce inflammation caused due to anxiety disorder.
  • Reduce your alcohol, caffeine, added sugar, high salt and high fat intake.
  • Try to spend time with your friends and family. Having a strong social network may help lower the risk of anxiety.

Habit Forming

Yes

Therapeutic Class

SEDATIVE-HYPNOTIC DRUGS

Pezlor-1 Tablet 10's Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Avoid taking Pezlor-1 Tablet 10's with alcohol as it can increase the side effects of this medicine like dizziness, drowsiness and difficulty in concentrating.

bannner image

Pregnancy

Unsafe

Pezlor-1 Tablet 10's is considered unsafe for pregnant women. Pezlor-1 Tablet 10's may cause harmful effects on the baby (foetus), so your doctor will weigh the benefits and potential risks before prescribing it.

bannner image

Breast Feeding

Unsafe

Pezlor-1 Tablet 10's passes into the breast milk and may harm the baby. Avoid breastfeeding while taking Pezlor-1 Tablet 10's.

bannner image

Driving

Unsafe

Pezlor-1 Tablet 10's may cause sleepiness, dizziness, and drowsiness. So, it is not recommended to drive or operate machinery after taking Pezlor-1 Tablet 10's.

bannner image

Liver

Caution

Pezlor-1 Tablet 10's to be taken with caution, especially if you have a history of liver disease. The dose may have to be adjusted by your doctor.

bannner image

Kidney

Caution

Pezlor-1 Tablet 10's to be taken with caution, especially if you have a history of kidney disease. The dose may have to be adjusted by your doctor.

bannner image

Children

Unsafe

The safety and effectiveness of Pezlor-1 Tablet 10's in children have not been established.

Have a query?

FAQs

Pezlor-1 Tablet 10's is used to treat epilepsy (status epilepticus) and anxiety disorder. It may also be prescribed as short-term therapy for sleeping difficulties due to anxiety and as a sedative prior to surgery.

Pezlor-1 Tablet 10's works by increasing levels of the chemical mediator which calms brain cells (neurons), known as gamma-aminobutyric acid (GABA), thus helps relieve anxiety.

Elderly patients are more likely to have confusion and sleepiness or age-related health issues, which may require caution and an adjustment in the dose. Consult your doctor if you have any concerns.

Pezlor-1 Tablet 10's is a habit-forming drug. It is not likely to be addictive if you take it for 2-4 weeks. Pezlor-1 Tablet 10's may be habit-forming if you previously had problems with drugs or alcohol. Therefore, notify your doctor if you had problems with recreational drugs or alcohol.

Do not stop taking Pezlor-1 Tablet 10's until instructed by your doctor. Stopping Pezlor-1 Tablet 10's suddenly may cause side effects like confusion, depression, nervousness, sweating and diarrhoea.

If you have taken a double dose or overdosed on Pezlor-1 Tablet 10's, you need immediate medical help. Call your doctor or go to the nearest hospital or clinic.

No, Pezlor-1 Tablet 10's is not an opioid. It belongs to the group of medications called benzodiazepines used for the treatment of epilepsy and anxiety disorders.

Yes, Pezlor-1 Tablet 10's can be used for short-term treatment of sleep difficulties caused by anxiety if prescribed by the doctor.

Pezlor-1 Tablet 10's will stay in our body's system for 12 hours.

If you get addicted to Pezlor-1 Tablet 10's, you might experience symptoms like, withdrawal symptoms like anxiety, tremors, insomnia, intense cravings and increased tolerance. Seek emergency medical help if you experience these symptoms.

Pezlor-1 Tablet 10's is not known to cause weight gain. However, you may experience weight changes due to loss of appetite.

Yes, Pezlor-1 Tablet 10's may cause depression if you suddenly stop taking it. Hence, continue taking this medicine for a prescribed period.

Yes, Pezlor-1 Tablet 10's may affect memory, particularly in older persons. Consult the doctor before taking Pezlor-1 Tablet 10's if you have any queries.

Pezlor-1 Tablet 10's can cause CNS and respiratory depression if Pezlor-1 Tablet 10's is taken more than the recommended dose, potentially leading to hypotension, extreme drowsiness, muscle weakness, confusion, ataxia and coma. Therefore, always follow the dose prescribed by the doctor based on your medical condition.

Country of origin

India

Manufacturer/Marketer address

House No-44, Ground Floor, Barthakur Mill Road, Ulubari, Guwahati, Kamrup,Assam, Pin -781007
Other Info - PEZ0025

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Aug 5, 2025 | 12:27 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.ncbi.nlm.nih.gov/books/NBK532890/
  2. https://www.drugs.com/drug-interactions/lorazepam.html
  3. https://www.nhs.uk/medicines/lorazepam/

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