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  3. PHARMAZIN 25MG TABLET

PHARMAZIN 25MG TABLET, Pack of 10 TABLETS
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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
PHARMAZIN 25MG TABLET is used to treat nausea and vomiting during a migraine, schizophrenia, mania, anxiety in the short term, and vertigo (dizziness) due to ear problems such as Meniere's disease. It contains Prochlorperazine, which works by inhibiting a natural chemical in the brain (dopamine) that stimulates the vomiting centre, thereby preventing nausea and vomiting. Besides this, it also controls psychotic symptoms in Schizophrenia and has a calming effect on people suffering from anxiety or mania. It may cause side effects such as dry mouth, drowsiness, headache, dizziness, stuffy nose, irritability, missed menstrual periods, impotence (difficulty maintaining an erection), anxiety, skin rash, skin redness, itching, or swelling. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

PROCHLORPERAZINE-25MG

Manufacturer/Marketer :

Plethico Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About PHARMAZIN 25MG TABLET

PHARMAZIN 25MG TABLET is used to treat nausea and vomiting during a migraine, schizophrenia, mania, anxiety in the short term, and vertigo (dizziness) due to ear problems such as Meniere’s syndrome. Nausea and vomiting are not diseases but are symptoms of many conditions like infections, motion sickness, an early stage of pregnancy, and gastroparesis (slow stomach emptying). Schizophrenia is a mental disorder that affects a person's ability to feel, think and behave clearly. Mania is a mental condition that causes intense excitement, high energy, and delusions (misbeliefs). Anxiety is a mental health disorder associated with fear, worry, and excessive nervousness. 

PHARMAZIN 25MG TABLET contains Prochlorperazine, which works by inhibiting a natural chemical in the brain (dopamine) that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ), thereby preventing nausea and vomiting. Besides this, PHARMAZIN 25MG TABLET also controls psychotic symptoms in Schizophrenia and has a calming effect on people suffering from anxiety or mania. 

Take PHARMAZIN 25MG TABLET as prescribed by your doctor. You are advised to take PHARMAZIN 25MG TABLET for as long as your doctor has prescribed it for you based on your medical condition. Some people may experience dry mouth, drowsiness, headache, dizziness, stuffy nose, irritability, missed menstrual periods, impotence (difficulty maintaining an erection), anxiety, skin rash, skin redness, itching, or swelling.  Most of these side effects of PHARMAZIN 25MG TABLET do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Do not take PHARMAZIN 25MG TABLET if you are known to be allergic to PHARMAZIN 25MG TABLET. PHARMAZIN 25MG TABLET should be used with caution in elderly patients above 65 years, as there is an increased risk of adverse effects. Do not take PHARMAZIN 25MG TABLET if you are pregnant or breastfeeding, as it may cause adverse effects on the baby. PHARMAZIN 25MG TABLET is not recommended for children below 1 year of age. Avoid exposure to direct sunlight while taking PHARMAZIN 25MG TABLET as it may cause the skin to be more sensitive to sunlight. If you have fits, depression, diabetes, pheochromocytoma (tumour on the adrenal gland), enlarged prostate gland, Parkinson’s disease, dementia (impairment in memory and thinking), myasthenia gravis (muscle weakness), glaucoma,  kidney, liver, heart or thyroid problems, inform your doctor before taking PHARMAZIN 25MG TABLET.

Uses of PHARMAZIN 25MG TABLET

Treatment of Nausea and vomiting in migraine, Schizophrenia, Anxiety disorder.

Directions for Use

Tablet: Swallow it as a whole with a glass of water. Do not crush, chew or break it. Avoid contact of tablet with your skin for a very long time as it may cause swelling, skin redness, and itching (contact skin sensitization).Tablet MD: Place the mouth-dissolving tablet in the mouth and allow it to dissolve. Do not swallow. Avoid handling the tablets with wet hands.Syrup: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Medicinal Benefits

PHARMAZIN 25MG TABLET contains Prochlorperazine, which inhibits dopamine secretion that induces the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, PHARMAZIN 25MG TABLET prevents nausea and vomiting. Also, PHARMAZIN 25MG TABLET controls psychotic symptoms in Schizophrenia and has a calming effect on people suffering from anxiety or mania.

How PHARMAZIN 25MG TABLET Works

PHARMAZIN 25MG TABLET contains Prochlorperazine, which works by inhibiting a natural chemical in the brain (dopamine) that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ), thereby preventing nausea and vomiting. Besides this, PHARMAZIN 25MG TABLET also controls psychotic symptoms in Schizophrenia and has a calming effect on people suffering from anxiety or mania.

Storage

Keep PHARMAZIN 25MG TABLET out of the sight and reach of children.
Side effects of Pharmazin 25mg Tablet
  • Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
  • Get sufficient sleep and manage stress which helps in improving white blood cell count.
  • Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
  • Try to prevent the factors that cause a decrease in white blood cells which may lead to impaired immunity.
  • Uncontrolled and involuntary movements need immediate medical attention.
  • Observe your movements and try to understand and control the particular movement.
  • Regularly do strengthening exercises to improve blood flow throughout the body and avoid involuntary movements.
  • Implement massage techniques to enhance blood flow to organs.
  • Take a balanced diet and quit smoking.
  • Practice yoga and meditation to improve thought processes and reduce uncontrolled and involuntary movements.
  • Restlessness is related to mental health and needs medical attention if it's severe.
  • Regular practice of meditation and yoga can help calm your mind. This can reduce restlessness.
  • Prevent smoking as it can impact your calmness of body and mind.
  • Talk to your friends and family about restlessness, who can provide a solution for why you feel restless.
  • Get sufficient sleep for a minimum of 6-7 hours to reduce restlessness.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.
Here are the step-by-step strategies to manage the side effects of " Muscle Pain" caused by medication usage:
  • Report to Your Doctor: Inform your doctor about the muscle pain, as they may need to adjust your medication.
  • Stretch Regularly: Gentle stretching can help relieve muscle pain and stiffness.
  • Stay Hydrated: Adequate water intake supports muscle health by removing harmful substances and maintaining proper muscle function.
  • Warm or Cold Compresses: Apply cold or warm compresses to the affected area to reduce pain and inflammation.
  • Rest and Relaxation: Adequate rest helps alleviate muscle strain, while relaxation techniques like deep breathing and meditation can soothe muscle tightness, calm the mind, and promote relief from discomfort.
  • Gentle Exercise: Participate in low-impact activities, such as yoga or short walks, to improve flexibility, reduce muscle tension, and alleviate discomfort.
  • Consult a physician: If your symptoms don't improve or get worse, go to the doctor for help and guidance.

What if I have taken an overdose of PHARMAZIN 25MG TABLET

Do not take more than the prescribed dose of PHARMAZIN 25MG TABLET as it may cause overdose. The symptoms of overdose include sleepiness, agitation, uncontrollable shaking of a part of the body, fits, irregular heartbeat, dry mouth, fever, constipation, coma, shuffling walk, difficulty falling asleep or staying asleep. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take PHARMAZIN 25MG TABLET if you are known to be allergic to PHARMAZIN 25MG TABLET. PHARMAZIN 25MG TABLET should be used with caution in elderly patients above 65 years, as there is an increased risk of adverse effects. Do not take PHARMAZIN 25MG TABLET if you are pregnant or breastfeeding as it may cause adverse effects in the baby. PHARMAZIN 25MG TABLET is not recommended for children below 1 year of age. Avoid consumption of alcohol with PHARMAZIN 25MG TABLET as it may increase adverse effects. You are recommended to avoid contact of PHARMAZIN 25MG TABLET with the skin for a long time as it may cause swelling, redness or itching of the skin. Avoid exposure to direct sunlight while taking PHARMAZIN 25MG TABLET as it may cause skin to more sensitive to sunlight. If you have fits, depression, diabetes, pheochromocytoma (tumour on adrenal gland), enlarged prostate gland, Parkinson’s disease, dementia (impairment in memory and thinking), myasthenia gravis (muscle weakness), glaucoma,  kidney, liver, heart or thyroid problems, inform your doctor before taking PHARMAZIN 25MG TABLET.

Drug-Drug Interactions

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ProchlorperazineMetoclopramide
Critical
ProchlorperazineMesoridazine
Critical

Drug-Drug Interactions

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ProchlorperazineMetoclopramide
Critical
How does the drug interact with Pharmazin 25mg Tablet:
Coadministration of metoclopramide and Pharmazin 25mg Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Metoclopramide with Pharmazin 25mg Tablet together is generally avoided as it can possibly result in an interaction, they can be taken together if advised by your doctor. However, if you experience muscle spasm or movements that you can't stop or control, such as lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye rolling, shaking or jerking of arms and legs, tremor, jitteriness, restlessness, pacing, and foot tapping, consult the doctor. Do not stop taking any medications without consulting a doctor.
ProchlorperazineMesoridazine
Critical
How does the drug interact with Pharmazin 25mg Tablet:
Coadministration of mesoridazine and Pharmazin 25mg Tablet can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking mesoridazine with Pharmazin 25mg Tablet is not recommended, but it can be taken together if prescribed by a doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or an irregular heartbeat. Do not stop taking any medications without consulting a doctor.
ProchlorperazineEscitalopram
Severe
How does the drug interact with Pharmazin 25mg Tablet:
Taking Pharmazin 25mg Tablet and Escitalopram together can raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Taking Pharmazin 25mg Tablet with Escitalopram together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop using any medications without a doctor's advice.
ProchlorperazineVemurafenib
Severe
How does the drug interact with Pharmazin 25mg Tablet:
Taking Pharmazin 25mg Tablet and Vemurafenib together can raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Although taking Pharmazin 25mg Tablet and Vemurafenib together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop using any medications without first talking to your doctor.
ProchlorperazineBepridil
Severe
How does the drug interact with Pharmazin 25mg Tablet:
Taking Pharmazin 25mg Tablet and Bepridil together can raise the risk of an abnormal heart rhythm that may be serious.

How to manage the interaction:
Although there is a possible interaction between Pharmazin 25mg Tablet and Bepridil, you can take these medicines together if prescribed by your doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop using any medications without a doctor's advice.
ProchlorperazineDroperidol
Severe
How does the drug interact with Pharmazin 25mg Tablet:
Taking Pharmazin 25mg Tablet and Droperidol together can raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Co-administration of Pharmazin 25mg Tablet with Droperidol can possibly result in an interaction, but it can be taken if your doctor has advised it. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop using any medications without a doctor's advice.
ProchlorperazineNilotinib
Severe
How does the drug interact with Pharmazin 25mg Tablet:
Taking Pharmazin 25mg Tablet and Nilotinib together can increase the risk of an abnormal heart rhythm.

How to manage the interaction:
There may be a possibility of interaction between Pharmazin 25mg Tablet and Nilotinib, but it can be taken if prescribed by a doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop using any medications without talking to your doctor.
ProchlorperazineDisopyramide
Severe
How does the drug interact with Pharmazin 25mg Tablet:
Taking Pharmazin 25mg Tablet with Disopyramide can increase the risk of irregular heart rhythm.

How to manage the interaction:
Co-administration of Disopyramide with Pharmazin 25mg Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. If you experience any symptoms like a fast or irregular heartbeat, dizziness, fainting, shortness of breath, or severe diarrhoea or vomiting, it's important to call your doctor right away. Do not stop using any medications without talking to your doctor.
ProchlorperazineZiprasidone
Severe
How does the drug interact with Pharmazin 25mg Tablet:
Taking Pharmazin 25mg Tablet and Ziprasidone together can raise the risk of an abnormal heart rhythm.

How to manage the interaction:
There may be a possibility of interaction between Pharmazin 25mg Tablet and Ziprasidone, but it can be taken if prescribed by a doctor. However, contact a doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop using any medications without talking to a doctor.
ProchlorperazineKetamine
Severe
How does the drug interact with Pharmazin 25mg Tablet:
Coadministration of Pharmazin 25mg Tablet with ketamine can increase the risk or severity of side effects.

How to manage the interaction:
Taking Pharmazin 25mg Tablet with Ketamine together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, contact your doctor if you experience dizziness, sleepiness, confusion, inability to concentrate, excessive sedation, and breathing problems. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and a low-fat diet, especially in small portions, as it will be easy for digestion. Avoid eating over sweet food and include more salty food, especially if you have been vomiting.

  • If you like to vomit at a specific time, avoid eating your favourite food at that particular time as your taste for that food may get turned off.

  • Include more cool beverages in your food like flavoured gelatin, carbonated beverages. And also, when you drink with a stray, sip slowly to avoid swallowing air that may lead to gas or acidity.

  • Drink any other liquid at least 30 minutes after eating food.

  • If the smell of food makes you feel sick (vomit), do not cook food as it may worsen your condition. Let someone else do cooking or use prepared food from the freezer.

  • Avoid consumption of alcohol as it may increase adverse effects.

Habit Forming

No

Therapeutic Class

ANTIPSYCHOTICS

PHARMAZIN 25MG TABLET Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Avoid consumption of alcohol with PHARMAZIN 25MG TABLET as it may increase the risk of adverse effects and cause severe breathing difficulties.

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Pregnancy

Unsafe

PHARMAZIN 25MG TABLET is a Category C pregnancy drug. It is not recommended for use during pregnancy, especially in the third trimester as it may cause adverse effects in the baby such as breathing problems, drowsiness, shaking, muscle stiffness or weakness. However, please consult a doctor if you are pregnant.

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Breast Feeding

Unsafe

Please consult a doctor if you are a breastfeeding mother as PHARMAZIN 25MG TABLET may not be safe to use in breastfeeding mothers.

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Driving

Caution

PHARMAZIN 25MG TABLET may cause dizziness, drowsiness or blurred vision in some people. Therefore, avoid driving if you feel drowsy, dizzy or experience any vision problems after taking PHARMAZIN 25MG TABLET.

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Liver

Caution

Take PHARMAZIN 25MG TABLET with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take PHARMAZIN 25MG TABLET with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

bannner image

Children

Caution

PHARMAZIN 25MG TABLET may be given to children above 1 year of age if prescribed by a doctor.

Have a query?

FAQs

PHARMAZIN 25MG TABLET is used to treat nausea and vomiting during a migraine, schizophrenia, mania, anxiety in the short term, and vertigo (dizziness) due to ear problems such as Meniere’s syndrome.

PHARMAZIN 25MG TABLET contains Prochlorperazine, an antipsychotic drug that works by inhibiting dopamine receptors that stimulate the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, PHARMAZIN 25MG TABLET prevents nausea and vomiting. Also, PHARMAZIN 25MG TABLET decreases the action of dopamine (a chemical messenger involved in transmitting messages between brain cells) in the brain and helps to control psychotic symptoms in Schizophrenia.

Yes, PHARMAZIN 25MG TABLET may be used to treat vertigo (spinning sensation) caused due to ear problems such as Meniere’s syndrome (a disorder of the inner ear).

PHARMAZIN 25MG TABLET may cause photosensitivity (extreme sensitivity to sunlight). Therefore, it is recommended to avoid exposure to direct sunlight while taking PHARMAZIN 25MG TABLET.

You are not recommended to take PHARMAZIN 25MG TABLET with alprazolam as co-administration of these medicines may increase adverse effects such as confusion, drowsiness, dizziness and difficulty in concentrating. However, please contact your doctor before using PHARMAZIN 25MG TABLET with other medicines.

PHARMAZIN 25MG TABLET should be used with caution in diabetes patients as it may cause an increase in blood sugar levels. Therefore, regular monitoring of blood sugar levels is recommended while taking PHARMAZIN 25MG TABLET if you are diabetic.

PHARMAZIN 25MG TABLET may cause skin redness, itching and swelling if it comes in contact with the skin for a long time. Therefore, avoid contact of PHARMAZIN 25MG TABLET with the skin for a long time as it may cause contact skin sensitization.

Yes, PHARMAZIN 25MG TABLET does expire. Please verify the expiry date on the pack and it refers to the last day of that month. PHARMAZIN 25MG TABLET should not be used after the expiry date.

No, PHARMAZIN 25MG TABLET is not available over the counter. It is a prescription medication. Because it contains prochlorperazine, which can have significant side effects and requires medical supervision.

PHARMAZIN 25MG TABLET is generally safe to use when taken as prescribed by your doctor. Do not exceed the recommended daily dose. It's important to follow your doctor's instructions.

You can take PHARMAZIN 25MG TABLET for as long as it is advised by your doctor. If you have any difficulty while taking PHARMAZIN 25MG TABLET, please consult your doctor.

No, PHARMAZIN 25MG TABLET is not known to be addictive. However, it's important to use PHARMAZIN 25MG TABLET only as prescribed by your doctor and not to exceed the recommended dosage.

The common side effects of PHARMAZIN 25MG TABLET are dry mouth, drowsiness, headache, dizziness, stuffy nose, irritability, missed menstrual periods, impotence (difficulty maintaining an erection), anxiety, skin rash, skin redness, itching, or swelling. If any of these side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

18-C, Sarojini Naidu Road, Swati Building, Ist Floor, Santacruz (W), Mumbai-400054
Other Info - PHA0004

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:43 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.medicines.org.uk/emc/files/pil.4553.pdf
  2. https://www.medicines.org.uk/emc/files/pil.98.pdf
  3. https://www.drugs.com/drug-interactions/prochlorperazine.html

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