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  3. Picocord GR 100 Tablet 10's

Picocord GR 100 Tablet 10's, Pack of 10 TabletS
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Picocord GR 100 Tablet is used to prevent and treat fungal infections. It contains posaconazole which works by inhibiting fungal cell growth and causing cell death. In some cases, this medicine may cause side effects such as diarrhoea, nausea, fever, vomiting, headache, and cough. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Composition :

POSACONAZOLE-100MG

Manufacturer/Marketer :

CONCORD DRUGS LTD

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Picocord GR 100 Tablet

Picocord GR 100 Tablet is in a class of medications called azole antifungals. It is used to prevent and treat fungal infections when other antifungal medicines have not worked, or you have had to stop taking them. It is also indicated for preventing invasive Aspergillus and Candida infections in patients at high risk of developing these infections due to being severely immunocompromised, such as hematopoietic stem cell transplant (HSCT) recipients with graft-versus-host disease (GVHD) or those with hematologic malignancies with prolonged neutropenia from chemotherapy.

Picocord GR 100 Tablet contains a medicine called posaconazole. It is a triazole antifungal agent and exerts its antifungal activity through the blockage of certain enzymes (P-450 dependent enzyme, sterol 14α-demethylase). This leads to inhibiting the synthesis of ergosterol, a key component of the fungal cell membrane, and the accumulation of methylated sterol precursors. This results in the inhibition of fungal cell growth and cell death. Thus, it treats infections.

Take Picocord GR 100 Tablet as prescribed by your doctor. You are advised to take Picocord GR 100 Tablet for as long as your doctor has prescribed it based on your medical condition. In some cases, you may experience diarrhoea, nausea, fever, vomiting, headache, coughing and low potassium levels in the blood. Most of these side effects of Picocord GR 100 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Inform your doctor if you are allergic or hypersensitive to any component present in Picocord GR 100 Tablet or if you are pregnant, suspect you are pregnant, plan to have a baby or are breastfeeding; your doctor will prescribe Picocord GR 100 Tablet only if the benefits outweigh the risk. Before taking the Picocord GR 100 Tablet , inform your doctor about your medical history and ongoing therapies to rule out any potential adverse effects or interactions.

Uses of Picocord GR 100 Tablet

Picocord GR 100 Tablet is used in the treatment of Fungal infections and prophylaxis of invasive Aspergillus and Candida infections in severely immunocompromised patients.

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush, break or chew it.Oral Suspension/syrup: Shake the bottle well before each use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper.

Medicinal Benefits

Posaconazole is an antifungal medication present in Picocord GR 100 Tablet . It is effective in treating fungal infections in adults. It is also indicated for preventing invasive Aspergillus and Candida infections in patients who are severely immunocompromised and at high risk of developing these infections, such as hematopoietic stem cell transplant (HSCT) recipients with graft-versus-host disease (GVHD) or those with hematologic malignancies with prolonged neutropenia from chemotherapy.

How Picocord GR 100 Tablet Works

Picocord GR 100 Tablet contains a medicine called posaconazole. It is a triazole antifungal agent and exerts its antifungal activity through the blockage of certain enzymes (P-450 dependent enzyme, sterol 14α-demethylase). This leads to inhibiting the synthesis of ergosterol, a key component of the fungal cell membrane, and the accumulation of methylated sterol precursors. This results in the inhibition of fungal cell growth and cell death. Thus, it treats infections.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Picocord GR 100 Tablet

Take Picocord GR 100 Tablet only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Inform your doctor if you are allergic or hypersensitive to any component present in Picocord GR 100 Tablet or if you are pregnant, suspect you are pregnant, plan to have a baby or are breastfeeding; your doctor will prescribe Picocord GR 100 Tablet only if the benefits outweigh the risk. Before taking the Picocord GR 100 Tablet , inform your doctor about your medical history and ongoing therapies to rule out any potential adverse effects or interactions. And also, let your doctor know before prescribing Picocord GR 100 Tablet if you have Arrhythmias and QTc Prolongation, liver problems, or low potassium, magnesium, or calcium levels in your blood.

Drug-Drug Interactions

verifiedApollotooltip
PosaconazoleTicagrelor
Critical
PosaconazoleEliglustat
Critical

Drug-Drug Interactions

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PosaconazoleTicagrelor
Critical
How does the drug interact with Picocord GR 100 Tablet:
Co-administration of Picocord GR 100 Tablet with Ticagrelor can increase the risk of bleeding.

How to manage the interaction:
Taking Ticagrelor with Picocord GR 100 Tablet is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.
PosaconazoleEliglustat
Critical
How does the drug interact with Picocord GR 100 Tablet:
Taking eliglustat with Picocord GR 100 Tablet can increase the levels of eliglustat in the blood.

How to manage the interaction:
Although there is an interaction between Picocord GR 100 Tablet and eliglustat, they can be taken together if prescribed by a doctor. However, contact a doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, a slow heart rate, or a weak pulse. Do not discontinue any medications without consulting a doctor.
PosaconazoleConivaptan
Critical
How does the drug interact with Picocord GR 100 Tablet:
When Picocord GR 100 Tablet is taken with Conivaptan, it can increase the blood levels and effects of conivaptan.

How to manage the interaction:
Although there is an interaction between Picocord GR 100 Tablet and conivaptan, they can be taken together if prescribed by a doctor. However, contact a doctor if you experience difficulty swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, or mood changes. Do not discontinue any medications without consulting a doctor.
PosaconazoleSaquinavir
Critical
How does the drug interact with Picocord GR 100 Tablet:
Taking saquinavir together with Picocord GR 100 Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is an interaction between Picocord GR 100 Tablet and saquinavir, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not discontinue any medications without consulting a doctor.
PosaconazoleSimvastatin
Critical
How does the drug interact with Picocord GR 100 Tablet:
Taking Picocord GR 100 Tablet with Simvastatin can increase the blood levels and effects of Simvastatin. This can increase the risk of side effects such as liver problems and rhabdomyolysis (which involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Picocord GR 100 Tablet and Simvastatin together is not recommended as it can lead to an interaction, but it can be taken if advised by a doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark-colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
PosaconazoleTolvaptan
Critical
How does the drug interact with Picocord GR 100 Tablet:
Taking Tolvaptan and Picocord GR 100 Tablet together results in an increase in the levels and effects of Tolvaptan.

How to manage the interaction:
Although there is an interaction between Tolvaptan and Picocord GR 100 Tablet, it can be taken if prescribed by a doctor. However, consult a doctor if you experience difficulty swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, mood changes, or seizures (fits). Do not stop using any medications without a doctor's advice.
PosaconazoleAtorvastatin
Critical
How does the drug interact with Picocord GR 100 Tablet:
Taking atorvastatin with Picocord GR 100 Tablet can increase the blood levels of atorvastatin. This can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Picocord GR 100 Tablet with atorvastatin, they can be taken together if advised by your doctor. However, contact the doctor if you experience unexplained muscle pain, weakness, fever, chills, joint pain or swelling, unusual bleeding, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark coloured urine, or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
PosaconazoleLovastatin
Critical
How does the drug interact with Picocord GR 100 Tablet:
Taking lovastatin with Picocord GR 100 Tablet can increase the levels of lovastatin in the blood which can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Lovastatin and Picocord GR 100 Tablet, they can be taken together if advised by a doctor. However, contact a doctor if you experience ever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes. Do not stop taking any medications without consulting a doctor.
PosaconazoleLurasidone
Critical
How does the drug interact with Picocord GR 100 Tablet:
Taking lurasidone together with Picocord GR 100 Tablet may result in significantly higher lurasidone blood levels.

How to manage the interaction:
Although there is an interaction between lurasidone and Picocord GR 100 Tablet, they can be used if prescribed by a doctor. However, consult a doctor if you have any abnormal muscle activity, dizziness, lightheadedness, headache, flushing, or fainting. Do not discontinue any medications without consulting a doctor.
PosaconazoleRanolazine
Critical
How does the drug interact with Picocord GR 100 Tablet:
When Picocord GR 100 Tablet is taken with Ranolazine, may significantly increase the blood levels and effects of Ranolazine.

How to manage the interaction:
Although there is an interaction between Picocord GR 100 Tablet and ranolazine, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Take the medication as directed by the doctor and at regular intervals if you take Picocord GR 100 Tablet for more than one day.
  • Do not use other over-the-counter medications, herbal or vitamin supplements without informing your pharmacist or doctor when you take Picocord GR 100 Tablet .
  • Continue taking your normal regular diet unless your doctor prescribes a specific diet.
  • It is advisable to follow a candida diet during yeast infections. This diet excludes sugar, gluten, certain dairy products, alcohol and switches to low-sugar fruits, non-starchy vegetables, and gluten-free foods.
  • A very high sugar or high-carbohydrate diet may increase the count of Candida in some people. It is better to avoid or limit alcohol and caffeine intake during Picocord GR 100 Tablet treatment to enhance a healthy lifestyle practice.

Habit Forming

No

Therapeutic Class

ANTIFUNGALS

Picocord GR 100 Tablet Substitute

Substitutes safety advice

  • Picasa-GR Tablet 10's

    by AYUR

    ₹450.18per tablet

  • Posatral 100 mg Tablet 10's

    by AYUR

    ₹324.72per tablet

  • Posaone 100 Tablet 10's

    by Others

    ₹533.00per tablet

  • Candipoz GR 100 Tablet 10's

    by Others

    ₹420.82per tablet

  • Cuvicon Tablet 10's

    by Others

    ₹729.80per tablet

Product Substitutes

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Alcohol

Consult your doctor

The interaction of Picocord GR 100 Tablet with alcohol is unknown. If you have any concerns regarding this, please discuss with your doctor.

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Pregnancy

Consult your doctor

Picocord GR 100 Tablet should not be used when pregnancy unless clearly necessary. So, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Picocord GR 100 Tablet .

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Breast Feeding

Consult your doctor

There is no substantial research yet on using Picocord GR 100 Tablet in breastfeeding/nursing mothers. Inform your doctor if you are a nursing mother before taking Picocord GR 100 Tablet ; your doctor will decide whether Picocord GR 100 Tablet can be taken by breastfeeding mothers.

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Driving

Caution

It is unknown whether Picocord GR 100 Tablet alters the ability to drive, so do not drive or operate machinery if you experience any symptoms affecting your ability to concentrate and react.

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Liver

Consult your doctor

Inform your doctor before taking the Picocord GR 100 Tablet if you have a liver impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Consult your doctor

Inform your doctor before taking the Picocord GR 100 Tablet if you have a kidney impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Children

Consult your doctor

Please consult a doctor before using Picocord GR 100 Tablet for children.

FAQs

Picocord GR 100 Tablet is used to treat fungal infections and prophylaxis of invasive Aspergillus and Candida infections in severely immunocompromised patients.

Picocord GR 100 Tablet contains a medicine called posaconazole. It is a triazole antifungal agent and exerts its antifungal activity through the blockage of certain enzymes (P-450 dependent enzyme, sterol 14α-demethylase). This leads to inhibiting the synthesis of ergosterol, a key component of the fungal cell membrane, and the accumulation of methylated sterol precursors. This results in inhibiting fungal cell growth and, ultimately, cell death. Thus, it treats infections.

Picocord GR 100 Tablet is not recommended for coadministration with anticoagulants, So if you are under anticoagulant therapy, inform your doctor before prescribing Picocord GR 100 Tablet .

If you are allergic to posaconazole or similar antifungals such as fluconazole, itraconazole, ketoconazole, or voriconazole, you should not use it. When combined with certain medications, posaconazole can have unfavourable or dangerous side effects.

Like all medicines, this medicine may cause side effects such as diarrhoea, nausea, fever, vomiting, headache, coughing and low potassium levels in the blood, although not everybody gets them. Most of these side effects of Picocord GR 100 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Take Picocord GR 100 Tablet as prescribed by your doctor. You are advised to take Picocord GR 100 Tablet for as long as your doctor has prescribed it for you based on your medical condition.

Country of origin

India

Manufacturer/Marketer address

Wr3P+W6G, Roorkee - Fatehpur - Kalsiya Marg, Nanheda Anantpur, Uttarakhand 247668
Other Info - PIC0170

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Author Details

Doctor imageDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Doctor imageDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jan 1, 2025 | 2:47 PM IST

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Reference

  1. https://www.medicines.org.uk/emc/product/5388/smpc
  2. https://www.medicines.org.uk/emc/files/pil.5388.pdf
  3. https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/022003s018s020,0205053s002s004,0205596s001s003lbl.pdf
  4. https://www.fda.gov/media/114097/download#:~:text=Posaconazole%20is%20an%20azole%20antifungal,2013%20and%20March%202014%2C%20respectively.&text=DPV%20will%20continue%20to%20monitor,with%20the%20use%20of%20posaconazole.
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