Posanat 100 mg Tablet 10's
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About Posanat 100 mg Tablet
Posanat 100 mg Tablet is an antifungal medicine used to prevent and treat certain fungal infections. It is often prescribed to people with weakened immune systems who are at a higher risk of developing invasive fungal infections. Posaconazole works by stopping fungi from growing and spreading, helping the body control the infection.
Take Posanat 100 mg Tablet exactly as prescribed and at the same time each day. Food instructions may vary depending on the formulation, so follow the directions provided with your medicine. Swallow the medicine as directed and complete the full course, even if you start to feel better. Do not stop treatment without consulting your doctor, as the infection may return or become more difficult to treat.
Some people may experience nausea, vomiting, diarrhoea, stomach discomfort, or headache. These side effects are usually mild. Contact your doctor if they become severe, persistent, or difficult to manage. Consult your doctor right away if you develop yellowing of the skin or eyes, dark urine, a fast or irregular heartbeat, or signs of a severe allergic reaction.
Before starting Posanat 100 mg Tablet , tell your doctor if you have liver disease, kidney problems, heart failure, heart rhythm problems, or low levels of potassium, magnesium, or calcium in your blood. Do not take this medicine if you are allergic to posaconazole or any of its ingredients. Some medicines must not be taken with posaconazole, including ergot medicines, sirolimus, certain cholesterol-lowering medicines, and some medicines that can cause dangerous changes in heart rhythm. Give your doctor a complete list of all medicines and supplements you take.
Your doctor may perform blood tests during treatment to monitor your liver function and, when needed, check the amount of posaconazole in your blood. If you are pregnant, planning a pregnancy, breastfeeding, an older adult, or considering this medicine for a child, consult your doctor before use. Your doctor will consider factors such as age, weight, kidney and liver function, other medicines, and individual treatment needs before recommending the most appropriate dose and formulation.
Uses of Posanat 100 mg Tablet
Your doctor may prescribe Posanat 100 mg Tablet to prevent or treat certain fungal infections, including:
- Prevention of invasive fungal infections: Helps prevent fungal infections in people with severely weakened immune systems, such as those receiving certain types of chemotherapy or undergoing a stem cell transplant.
- Invasive aspergillosis: Treats fungal infections caused by Aspergillus, including infections that have not improved with or cannot be treated using other antifungal medicines.
- Other difficult-to-treat fungal infections: May be used to treat certain fungal infections, such as fusariosis, when other antifungal treatments have not worked or are not suitable.
- Fungal infections of the mouth and throat: Certain formulations may be used to treat oral thrush when other antifungal medicines have not worked or are not suitable.
Key Benefits
When used as prescribed, Posanat 100 mg Tablet may provide the following benefits:
- Helps protect people at high risk: Reduces the risk of invasive fungal infections in people whose immune systems are severely weakened.
- Helps control difficult fungal infections: Stops fungi from growing and spreading, giving the body a better chance to fight the infection.
- Supports recovery: Treating or preventing fungal infections may help reduce infection-related symptoms and support recovery during treatment for other health conditions.
- Helps prevent complications: Early and effective control of fungal infections may reduce the risk of the infection spreading to other parts of the body.
Directions for Use
- Posanat 100 mg Tablet should be taken with food, preferably a high-fat meal, to ensure proper absorption.
- It is recommended to take Posanat 100 mg Tablet twice on the first day, then once daily afterward, or as advised by your doctor.
- Swallow Posanat 100 mg Tablet as a whole with a glass of water.
- Do not crush, chew, or break it.
How Posanat 100 mg Tablet Works
Alcohol
Consult your doctor
The interaction of Posanat 100 mg Tablet with alcohol is unknown. If you have any concerns regarding this, please discuss with your doctor.
Pregnancy
Consult your doctor
Posanat 100 mg Tablet should not be used when pregnancy unless clearly necessary. So, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Posanat 100 mg Tablet .
Breast Feeding
Consult your doctor
There is no substantial research yet on using Posanat 100 mg Tablet in breastfeeding/nursing mothers. Inform your doctor if you are a nursing mother before taking Posanat 100 mg Tablet ; your doctor will decide whether Posanat 100 mg Tablet can be taken by breastfeeding mothers.
Driving
Caution
It is unknown whether Posanat 100 mg Tablet alters the ability to drive, so do not drive or operate machinery if you experience any symptoms affecting your ability to concentrate and react.
Liver
Consult your doctor
Inform your doctor before taking the Posanat 100 mg Tablet if you have a liver impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.
Kidney
Consult your doctor
Inform your doctor before taking the Posanat 100 mg Tablet if you have a kidney impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.
Children
Consult your doctor
Please consult a doctor before using Posanat 100 mg Tablet for children.
Heart
Caution
Posanat 100 mg Tablet should be taken with caution in patients with heart problems. Therefore, please inform your doctor before using Posanat 100 mg Tablet .
Geriatrics
Caution
Posanat 100 mg Tablet should be given with caution in elderly patients due to an increased risk of side effects. If you have any concerns about the usage of Posanat 100 mg Tablet in geriatrics, please consult your doctor.
What if I have taken an overdose of Posanat 100 mg Tablet
Diet & Lifestyle Advise
- Take with high-fat meals: Whenever possible, take your tablet with a full meal or a high-fat snack, as this helps your body absorb the medicine more efficiently.
- Avoid grapefruit: Do not eat grapefruit or drink grapefruit juice while taking Posanat 100 mg Tablet , as it can raise the levels of the medicine in your blood to unsafe levels.
- Practice strict hygiene: Wash your hands frequently and keep your living spaces clean to minimise exposure to environmental moulds and fungi, especially if your immune system is weak.
- Avoid dusty environments: Stay away from construction sites, soil, agricultural areas, or dusty places where fungal spores are highly concentrated in the air.
Have a query?
How Soon It Starts Working
The time required for Posanat 100 mg Tablet to start to work: Posanat 100 mg Tablet shows its action within 2 to 4 hours of administration. The time for which the effects of Posanat 100 mg Tablet last: Posanat 100 mg Tablet effect lasts for 12 to 24 hours.
What if you forget to take Posanat 100 mg Tablet
Storage
Drug Warnings
- Complete the full course: Continue taking Posanat 100 mg Tablet for the full duration prescribed by your doctor, even if you start to feel better. Stopping treatment early may allow the fungal infection to return or become more difficult to treat.
- Attend regular liver checks: Your doctor may order blood tests to monitor your liver function during treatment.
- Attend blood level tests if advised: Your doctor may sometimes measure the amount of posaconazole in your blood to check that you are receiving enough medicine and reduce the risk of treatment failure or side effects.
- Report changes in your heartbeat: Consult your doctor right away if you experience a fast, pounding, fluttering, or irregular heartbeat.
- Share your complete medicine list: Tell your doctor about all prescription medicines, over-the-counter medicines, vitamins, and supplements you take, as posaconazole can interact with several medicines.
- Tell your doctor about kidney problems: Inform your doctor if you have kidney problems. Your doctor will consider your kidney function and the formulation being used when planning your treatment.
- Use in children only as prescribed: Posaconazole may be used in certain children, but the suitable formulation and dose depend on factors such as age, weight, and the condition being treated. Give Posanat 100 mg Tablet to a child only under medical supervision.
- Ask about other formulations if you cannot take oral medicine: Posaconazole is also available as an intravenous (IV) infusion, which may be given in a hospital or healthcare setting when oral treatment is not suitable.
Drug-Drug Interactions
Drug-Drug Interaction Summary:
The following medicines may interact with Posanat 100 mg Tablet and require closer monitoring or dose adjustments:
- Ergot medicines: Do not take posaconazole with ergot medicines, such as ergotamine or dihydroergotamine. This combination may cause dangerously reduced blood flow to the arms, legs, or other parts of the body.
- Medicines that affect heart rhythm: Certain medicines that can prolong the QT interval must not be taken with posaconazole because the combination may cause dangerous changes in heart rhythm.
- Sirolimus: Do not take sirolimus with posaconazole, as posaconazole can greatly increase the amount of sirolimus in the blood and raise the risk of serious side effects.
- Tacrolimus and cyclosporine: Posaconazole may increase the levels of these medicines in the blood. Your doctor may adjust the dose and monitor the medicine levels more closely.
- Certain cholesterol-lowering medicines: Do not take posaconazole with simvastatin or lovastatin, as it may greatly increase their levels and raise the risk of severe muscle damage. Other statins, including atorvastatin, may also require closer monitoring or a change in treatment.
- Blood thinners: Posaconazole may increase the effects of some blood thinners and raise the risk of bleeding. Your doctor may recommend closer monitoring.
- Acid-reducing medicines: Some acid-reducing medicines may reduce the absorption of certain posaconazole formulations. Ask your doctor or pharmacist whether these medicines can be taken together.
Drug-Drug Interactions
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Taking eliglustat with Posanat 100 mg Tablet can increase the levels of eliglustat in the blood.
How to manage the interaction:
Although there is an interaction between Posanat 100 mg Tablet and eliglustat, they can be taken together if prescribed by a doctor. However, contact a doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, a slow heart rate, or a weak pulse. Do not discontinue any medications without consulting a doctor.
Taking Posanat 100 mg Tablet with Simvastatin can increase the blood levels and effects of Simvastatin. This can increase the risk of side effects such as liver problems and rhabdomyolysis (which involves the breakdown of skeletal muscle tissue).
How to manage the interaction:
Taking Posanat 100 mg Tablet and Simvastatin together is not recommended as it can lead to an interaction, but it can be taken if advised by a doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark-colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Co-administration of Posanat 100 mg Tablet with Ticagrelor can increase the risk of bleeding.
How to manage the interaction:
Taking Ticagrelor with Posanat 100 mg Tablet is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.
Using ivabradine together with Posanat 100 mg Tablet may significantly increase the blood levels and effects of ivabradine.
How to manage the interaction:
Taking Ivabradine with Posanat 100 mg Tablet together is generally not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
When Posanat 100 mg Tablet is taken with Cisapride, it can lower the rate at which Cisapride is broken down in the body.
How to manage the interaction:
Taking Posanat 100 mg Tablet with Cisapride is not recommended, please consult your doctor before taking it. They can be taken together if advised by your doctor. However, contact your doctor if you experience any symptoms. Do not stop taking any medications without consulting a doctor.
Taking saquinavir together with Posanat 100 mg Tablet can increase the risk of an irregular heart rhythm.
How to manage the interaction:
Although there is an interaction between Posanat 100 mg Tablet and saquinavir, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not discontinue any medications without consulting a doctor.
Taking pimozide with Posanat 100 mg Tablet can increase the levels of pimozide in the blood, which can lead to an increased risk of abnormal heart rhythm.
How to manage the interaction:
Although there is an interaction between Posanat 100 mg Tablet and pimozide, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience severe or prolonged diarrhea, vomiting dizziness, lightheadedness, fainting, or shortness of breath. Do not discontinue any medications without consulting a doctor.
Coadministration of silodosin and Posanat 100 mg Tablet may significantly increase the blood levels and effects of silodosin.
How to manage the interaction:
Although there is an interaction between Posanat 100 mg Tablet and Silodosin, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, nasal congestion, and headache. Do not discontinue any medications without consulting a doctor.
Taking lovastatin with Posanat 100 mg Tablet can increase the levels of lovastatin in the blood which can increase the risk of side effects.
How to manage the interaction:
Although there is an interaction between Lovastatin and Posanat 100 mg Tablet, they can be taken together if advised by a doctor. However, contact a doctor if you experience ever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes. Do not stop taking any medications without consulting a doctor.
Coadministration of Posanat 100 mg Tablet with eplerenone can increase the blood levels of eplerenone. This can increase the risk of serious side effects, including hyperkalemia (high blood potassium).
How to manage the interaction:
Although there is an interaction between Posanat 100 mg Tablet and eplerenone, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Drug-Food Interactions
Drug-Food Interaction Summary:
Certain foods or drinks may affect the safety or tolerability of Posanat 100 mg Tablet . Important interactions include:
- Alcohol: Alcohol may increase the risk of liver problems and worsen side effects such as nausea, dizziness, or stomach discomfort. Ask your doctor whether it is safe to drink alcohol during treatment.
Drug-Food Interactions
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Reference
- Electronic Medicines Compendium (EMC). Product Summary of Product Characteristics (SmPC). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
- Electronic Medicines Compendium (EMC). Pil.5388 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
- U.S. Food and Drug Administration (FDA). 022003S018S020,0205053S002S004,0205596S001S003Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
- Posaconazole Posaconazole. 2006. [Accessed on 29 Mar. 2019]Check here
- Central Drugs Standard Control Organisation (CDSCO). [Accessed on 29 Mar. 2019]Check here
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Recommended for a 30-day course: 2 Strips