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Pilorute-EP Tablet is a combination medicine used in the treatment of piles (haemorrhoids). This medicine helps strengthen the walls of tiny blood vessels and prevent leakage and fragility, enhances blood flow by decreasing blood viscosity/thickness, reduces inflammation (redness and swelling) and promotes better healing. It is also used to treat chronic venous insufficiency of lower limbs. Common side effects include nausea, diarrhoea, vomiting, and indigestion.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Mankind Pharma Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Pilorute-EP Tablet

Pilorute-EP Tablet is a medication specifically used to manage and treat haemorrhoids, commonly known as piles. It helps relieve the highly uncomfortable symptoms of painful, swollen, and bleeding veins in the anal region. Doctors typically prescribe this medicine for both short-term relief from acute flare-ups and long-term recovery support.

To get the best results, you must take Pilorute-EP Tablet regularly and consistently exactly as prescribed by your healthcare provider. It is highly recommended to take this tablet with food to reduce the risk of any mild stomach discomfort. Making simple diet and lifestyle adjustments, such as eating more fibre and staying hydrated, will significantly improve your treatment outcomes.

Pilorute-EP Tablet is generally well-tolerated, though some people may experience mild side effects like an upset stomach, nausea, or a headache. If you experience severe or persistent diarrhoea, intense abdominal pain, or any signs of an allergic reaction, you should stop taking the medication and consult your doctor immediately.

Do not take this if you have a known allergy to any of the ingredients in this formulation. Talk to your doctor before starting Pilorute-EP Tablet if you have a history of chronic bowel disorders, severe liver damage, or kidney problems. Your doctor will help determine if this medication is safe and appropriate for your medical history.

Avoid drinking alcohol while taking this medicine, as alcohol can cause dehydration and worsen stomach irritation, which can delay your recovery. If you are pregnant, breastfeeding, or an elderly individual, consult your doctor or pharmacist before using this medicine, as safety data for these specific groups may be limited. This medicine is not recommended for children unless specifically prescribed by a doctor. Parents or caregivers should consult a paediatrician before giving this medicine to a child.

Uses of Pilorute-EP Tablet

Pilorute-EP Tablet is used to manage and treat haemorrhoids, commonly known as piles. The detailed uses are as follows:

  • Haemorrhoids (piles): It may help relieve symptoms such as rectal bleeding, itching, and pain during bowel movements. Some early evidence suggests it may also help reduce swelling associated with haemorrhoids. It is generally used for Grade I–II haemorrhoids to help manage symptoms such as bleeding, pain, and discomfort, while Grade III–IV haemorrhoids may require additional treatments, such as procedures or surgery, depending on severity and response to treatment. 
     

Key Benefits

Pilorute-EP Tablet brings real-world relief by targeting the root causes of hemorrhoidal discomfort. This medicine brings several key health benefits:

  • Reduces rectal bleeding: It may help reduce bleeding during bowel movements and relieve anxiety. Reduced bleeding over time may theoretically lower the risk of iron-deficiency anaemia, although this has not been established for this medicine.
  • Relieves pain and swelling: It may help reduce swelling and throbbing pain, making sitting, standing, and walking more comfortable.
  • Helps prevent recurrence: Some early evidence suggests it may support blood vessel health, which may help reduce the recurrence of haemorrhoid symptoms. Further research is needed to confirm this benefit.

Directions for Use

  • Pilorute-EP Tablet should be taken on an empty stomach.
  • Follow your doctor’s recommendations on the dosage and timing of this medication to achieve optimal results.
  • Swallow Pilorute-EP Tablet as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Pilorute-EP Tablet Works

Pilorute-EP Tablet contains natural plant compounds, including polyphenols and terpenoids (natural plant compounds with anti-inflammatory properties), that are traditionally used to help relieve the symptoms of haemorrhoids. Most evidence comes from traditional use and small clinical studies, so more research is needed to confirm its effectiveness and mechanism. Preliminary evidence suggests these compounds may help reduce inflammation, support small blood vessels (capillaries), and reduce capillary permeability (making blood vessel walls less leaky), which may help relieve symptoms and support the healing of delicate rectal tissues. However, further research is needed to confirm these benefits.
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Alcohol

Caution

You are advised to avoid alcohol with Pilorute-EP Tablet as there may be an interaction.

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Pregnancy

Caution

Not enough studies have been conducted to conclusively ascertain the effects of Pilorute-EP Tablet on pregnancy. Consult your doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Caution

Not enough studies have been conducted to conclusively ascertain the effects of Pilorute-EP Tablet on breastfeeding. Consult your doctor if you are breastfeeding.

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Driving

Safe if prescribed

Pilorute-EP Tablet does not affect your ability to drive.

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Liver

Caution

Please consult your doctor if you have any concerns regarding the usage of Pilorute-EP Tablet in patients with liver impairment.

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Kidney

Caution

Pilorute-EP Tablet should be used with caution in case of a history of renal impairment or kidney disease. Please consult your doctor in case of any concerns.

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Children

Caution

Pilorute-EP Tablet should be used with caution and only in prescribed paediatric doses in children below 12 years of age. Please consult your physician if you have any concerns.

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Heart

Caution

There is limited information about the usage of Pilorute-EP Tablet in patients with heart problems. Please consult your doctor if you have any concerns.

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Geriatrics

Caution

Pilorute-EP Tablet should be given with caution in elderly patients due to an increased risk of side effects. It is important to inform your doctor before using it.

What if I have taken an overdose of Pilorute-EP Tablet

If you suspect an overdose or have accidentally taken too many tablets, seek immediate medical attention.

Diet & Lifestyle Advise

  • Increase dietary fibre: Eat plenty of fruits, vegetables, beans, and whole grains to soften your stools, making them easier to pass without straining.
  • Stay well-hydrated: Drink at least 8 to 10 glasses of water daily to keep your digestive tract functioning smoothly and prevent constipation.
  • Avoid straining: Do not strain or hold your breath during bowel movements, as this increases pressure on the rectal veins and can worsen piles.
  • Use warm sitz baths: Sit in a tub of warm water for 15 to 20 minutes two to three times a day to soothe the anal region, reduce pain, and improve local blood circulation.
  • Avoid prolonged sitting: Take regular breaks to walk around if you work at a desk, as sitting for long periods puts extra pressure on the veins in your lower body.
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Have a query?

How Soon It Starts Working

The time required for Pilorute-EP Tablet to start to work: The exact onset time of Pilorute-EP Tablet is clinically unknown. The time for which the effects of Pilorute-EP Tablet last: The duration of Pilorute-EP Tablet’s effect is clinically not established.

What if you forget to take Pilorute-EP Tablet

If you miss a dose, take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one.

Storage

•Store Pilorute-EP Tablet at room temperature, ideally between 15°C and 30°C (59°F to 86°F). •Keep the tablets in their original packaging to protect them from direct sunlight, heat, and moisture.

Drug Warnings

  • Inspect before use: Always inspect the blister foil before use; do not take the tablet if the packaging is torn, punctured, or damaged.
  • Complete the full course: Complete the entire course of treatment prescribed by your doctor, even if your pain and bleeding resolve within the first few days.
  • Seek medical attention immediately: If you have a large amount of fresh rectal bleeding, a prolapsed haemorrhoid (a haemorrhoid that has slipped outside the anal opening) that cannot be pushed back, severe pain, fever, or are unable to pass stool or gas, seek medical help immediately.
  • Avoid strong laxatives: Avoid taking strong over-the-counter laxatives unless advised by your doctor, as some laxatives can irritate the bowel and worsen hemorrhoidal symptoms.
  • Consult your doctor: If symptoms do not improve or haemorrhoids are more advanced, your doctor may recommend procedures such as rubber band ligation, sclerotherapy, or surgery.  
     

verifiedApollotooltip

Inform your doctor if you are taking any of the following medicines, as they may interact.

  • Blood thinners (anticoagulants): If you are taking medicines such as warfarin or other blood thinners, tell your doctor before using this medicine. While a direct drug interaction has not been clearly established, using them together may increase the risk of bleeding. Persistent or heavy rectal bleeding should be evaluated by a doctor, as it may have causes other than haemorrhoids.  
  • NSAIDs (painkillers): If you are taking medicines such as ibuprofen or diclofenac, tell your doctor before using this medicine. Although a direct interaction with Pilorute-EP Tablet has not been established, NSAIDs can increase the risk of gastrointestinal bleeding, so your doctor may recommend appropriate monitoring if both are used.
  • Stool softeners or laxatives: These may be used along with this medicine if recommended by your doctor to help reduce straining during bowel movements.
     

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verifiedApollotooltip

Certain foods or drinks may affect the safety or tolerability. Important interactions include:

  • Spicy and processed foods: Avoid eating highly spiced, hot, or heavily processed foods while treating haemorrhoids, as these can irritate your digestive tract and make bowel movements painful, reducing the effectiveness of your recovery.

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANORECTAL PREPARATIONS]

FAQs

Pilorute-EP Tablet belongs to the group of medicines called anorectal preparations used to treat haemorrhoids (piles).
Pilorute-EP Tablet works by shrinking engorged veins and reducing the pain and inflammation associated with piles, thereby relieving any discomfort or itching.
Continue using Pilorute-EP Tablet for as long as your doctor has prescribed it to you, to treat your condition effectually. Do not be reluctant to speak with your doctor if you experience any difficulty while using Pilorute-EP Tablet.
Pilorute-EP Tablet should be used with caution in dialysis patients. Consult your doctor for alternative remedies.
The symptoms of anal fissure and piles are similar. However, anal fissure is a small tear in the mucosa that lines the anus, whereas piles are the inflamed and swollen veins in the rectum and anus that cause discomfort, pain and bleeding.
In case you miss a dose of Pilorute-EP Tablet, take it as soon as possible. However, if it is too close to the next dose, revert to the original schedule. Do not ever take a double dose.
You are recommended to consult your doctor before taking other medicines with Pilorute-EP Tablet to avoid drug interactions.
No, Pilorute-EP Tablet cannot be used to treat fissures. Unlike haemorrhoids, fissures are mainly caused due to tearing of the anal tissue. Pilorute-EP Tablet is used to treat haemorrhoids (piles).
Pilorute-EP Tablet may cause side effects such as constipation, diarrhoea, stomach pain, dry mouth and rash. If these side effects persist or worsen, please consult your doctor.
There are several brands with the same active ingredient as Pilorute-EP Tablet. However, it is recommended to take the brand prescribed by a doctor only.
Yes, Pilorute-EP Tablet is an Ayurvedic formulation.
No, Pilorute-EP Tablet is not an antibiotic. Pilorute-EP Tablet contains a plant extract with anti-inflammatory property used to treat piles.
Yes, Pilorute-EP Tablet is effective for piles. It helps to provide relief from symptoms such as pain, itching, bleeding and discomfort due to piles.
The treatment with Pilorute-EP Tablet lasts for 14 days as per the product label. However, you are recommended to use Pilorute-EP Tablet for as long as it is advised by your doctor. The duration varies based on patient’s condition, severity and response to the treatment.
Pilorute-EP Tablet contains Euphorbia prostrata extract.
Take Pilorute-EP Tablet as advised by your doctor. Swallow it as whole with a glass of water. Do not break, crush or chew it.
It is highly recommended to take Pilorute-EP Tablet with or immediately after a meal. Taking this medicine with food helps protect your stomach lining and minimises the risk of mild stomach upset or nausea. Talk to your doctor or pharmacist if you experience persistent stomach issues.
There is limited clinical safety data regarding the use of Pilorute-EP Tablet in pregnant women. Therefore, you should avoid using it unless your doctor specifically determines it is necessary. Talk to your doctor before taking this or any other medication if you are pregnant.
It is best to avoid alcohol while taking Pilorute-EP Tablet. Alcohol can dehydrate your body, which leads to harder stools and constipation, potentially worsening your haemorrhoid symptoms and delaying healing.
Medicine is thought to act on blood vessels throughout the body, although clinical evidence is still emerging. It may help relieve the symptoms of both internal and external haemorrhoids by supporting blood vessel health and helping reduce inflammation. Talk to your doctor to get an accurate diagnosis and the most appropriate treatment for your condition.
No, you should not stop taking the medicine early just because your bleeding has stopped. Stopping the medication prematurely may allow the inflammation and swelling to return. Always complete the full treatment course advised by your doctor.

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Country of origin

India

Manufacturer/Marketer address

208, Okhla Industrial Estate, Phase III, New Delhi - 110020
Other Info - PIL0217
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