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  3. Piolon 15 Tablet 10's

Piolon 15 Tablet 10's, Pack of 10 TABLETS
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Composition :

PIOGLITAZONE-15MG

Manufacturer/Marketer :

Knoll Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Piolon 15mg Tablet

Piolon 15mg Tablet is an anti-diabetic medicine belonging to the class of thiazolidinedione (TZD), also called 'glitazones', used to treat type 2 (non-insulin-dependent) diabetes mellitus. Type 2 diabetes is an illness where the body doesn't make enough insulin, or the insulin that it makes doesn't work properly. This is diabetes that usually develops in adulthood.

Piolon 15mg Tablet contains Pioglitazone, which helps control the sugar level in your blood when you have type 2 diabetes by helping your body make better use of the insulin it produces.

Piolon 15mg Tablet should be taken with food or an empty stomach. The most common side effects of Piolon 15mg Tablet are upper respiratory tract infection, headache, sinusitis, myalgia (muscle pain), and pharyngitis. Most of these side effects of Piolon 15mg Tablet do not require medical attention and gradually resolve over time. Please consult your doctor if these side effects become troublesome.

Piolon 15mg Tablet should not be stopped even if you feel better without consulting your doctor. If you stop taking Piolon 15mg Tablet suddenly, it may increase your sugar levels, which could further increase the risk of eyesight loss (retinopathy), kidney damage (nephropathy) and nerve damage (neuropathy). Piolon 15mg Tablet should not be taken if you have type 1 diabetes mellitus, if you are hypersensitive (allergic) to any of the ingredients in Piolon 15mg Tablet , have heart failure or have had heart failure in the past, diabetic ketoacidosis (a complication of diabetes causing rapid weight loss, nausea or vomiting), severe kidney or liver disease, bladder cancer. Please inform your doctor if you have any heart disease, are or are planning to get pregnant or are breastfeeding. The safety and efficacy of Piolon 15mg Tablet in children under 18 years have not been established, so it should not be given to them.

Uses of Piolon 15mg Tablet

Treatment of Type 2 diabetes mellitus

Directions for Use

Swallow the medicine as a whole with water; do not crush, break or chew it.

Key Benefits

Piolon 15mg Tablet is an antidiabetic drug (thiazolidinedione/glitazones) used along with a proper diet and exercise to control high blood sugar (hyperglycaemia) in patients with type 2 diabetes. Piolon 15mg Tablet works by helping to restore your body's appropriate response to insulin, thereby lowering your blood sugar.

How Piolon 15mg Tablet Works

Piolon 15mg Tablet contains Pioglitazone, which helps control the sugar level in your blood when you have type 2 diabetes by helping your body make better use of the insulin it produces.

Storage

Store in a cool and dry place away from sunlight
Side effects of Piolon 15 Tablet
  • If you experience low blood sugar levels, inform your doctor. They will assess the severity and make recommendations for the next actions.
  • Your doctor will assess your symptoms, blood sugar levels, and overall health before recommending the best course of action, which may include treatment, lifestyle modifications, or prescription adjustments.
  • Follow your doctor's instructions carefully to manage the episode and adjust your treatment plan.
  • Make medication adjustments as recommended by your doctor to prevent future episodes.
  • Implement diet and lifestyle modifications as your doctor advises to manage low blood sugar levels.
  • Monitor your blood sugar levels closely for patterns and changes.
  • Track your progress by recording your blood sugar levels, food intake, and physical activity.
  • Seek further guidance from your doctor if symptoms persist or worsen so that your treatment plan can be revised.
  • Eat fiber-rich foods, fruits, and vegetables, and track your food intake to monitor calorie consumption.
  • Limit takeout and restaurant meals, and weigh yourself weekly to stay motivated.
  • Build balanced meals, allow yourself to enjoy treats in moderation, and prioritize sleep and stress management through exercise and relaxation techniques.
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.
  • Heart failure needs immediate medical attention. To manage this effect, the doctor's instructions must be followed strictly.
  • Take care of change in your weight as there can be sudden changes.
  • Rest and refrain from physical activity, and restart after a few days.
  • Reduce your salt intake and control your diet with the help of a dietician.
  • Track your symptoms and keep your follow-up appointments to manage severe side effects.
  • Heart failure needs immediate medical attention. To manage this effect, the doctor's instructions must be followed strictly.
  • Take care of change in your weight as there can be sudden changes.
  • Rest and refrain from physical activity, and restart after a few days.
  • Reduce your salt intake and control your diet with the help of a dietician.
  • Track your symptoms and keep your follow-up appointments to manage severe side effects.
  • Chest pain may last for a while and needs immediate medical attention as it is a significant health issue to be attended to.
  • Take rest and refrain from doing physical activity for a while, and restart after a few days.
  • Try applying an ice pack to the strained area for at least 20 minutes thrice a day. Ice pack thus helps reduce inflammation.
  • Sit upright and maintain proper posture if there is persistent chest pain. • Use extra pillows to elevate your position and prop your chest up while sleeping.

What if I have taken an overdose of Piolon 15mg Tablet

Do not take more than the prescribed dose of Piolon 15mg Tablet as it may cause overdose resulting in low blood sugar. The symptoms include sweating, tremors, stomach pain, extreme weakness, blurred vision, trouble speaking, seizures (fits) and confusion. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Fluid retention (oedema) may occur and can lead to congestive heart failure so, a combination of use with insulin and use in heart failure may increase the risk in patients taking Piolon 15mg Tablet . You should not take Piolon 15mg Tablet if you have kidney disease, as measured by a blood test. Piolon 15mg Tablet , when used with or without insulin, $ name tends to lower the blood sugar level. So, the doctor may lower the dose of insulin. Increased fractures may be reported in some women taking Piolon 15mg Tablet . Patients with bladder cancer and macular oedema (fluid build-up in the macula part of the retina of the eye) should consult the doctor before using Piolon 15mg Tablet .

Drug-Drug Interactions

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PioglitazoneGatifloxacin
Critical
PioglitazoneLeflunomide
Severe

Drug-Drug Interactions

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PioglitazoneGatifloxacin
Critical
How does the drug interact with Piolon 15 Tablet:
Co-administration of Piolon 15 Tablet with Gatifloxacin may sometimes affect blood glucose levels. Both high blood glucose and, less frequently, low blood glucose have been reported.

How to manage the interaction:
Although there is a possible interaction, Piolon 15 Tablet can be taken with Gatifloxacin if prescribed by the doctor. Consult the prescriber if you experience symptoms such as nervousness, confusion, headache, dizziness, drowsiness, tremors, nausea, hunger, weakness, excessive sweating, rapid heartbeat, increased urination, increased thirst, and increased hunger. Maintaining blood glucose levels is advised. Do not discontinue any medications without a doctor's advice.
PioglitazoneLeflunomide
Severe
How does the drug interact with Piolon 15 Tablet:
Co-administration of Piolon 15 Tablet and Leflunomide may increase the risk of liver damage.

How to manage the interaction:
Although taking Piolon 15 Tablet and Leflunomide together can possibly result in an interaction, it can be taken if a doctor has prescribed it. However, if you have any of the following symptoms: fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, fatigue, lack of appetite, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
PioglitazoneLomitapide
Severe
How does the drug interact with Piolon 15 Tablet:
Co-administration of Piolon 15 Tablet and Lomitapide may increase the risk of liver damage.

How to manage the interaction:
Although taking Lomitapide and Piolon 15 Tablet together can possibly result in an interaction, it can be taken if a doctor has prescribed it. However, if you have any of the following symptoms: fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, fatigue, lack of appetite, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
PioglitazoneMipomersen
Severe
How does the drug interact with Piolon 15 Tablet:
Co-administration of Mipomersen and Piolon 15 Tablet may increase the risk of liver damage.

How to manage the interaction:
Although taking Piolon 15 Tablet and Mipomersen together can possibly result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, nausea, vomiting, dark urine, light stools, and skin or eye yellowing, decreased hunger, consult the doctor. Do not stop using any medications without talking to the doctor.
PioglitazoneKetoconazole
Severe
How does the drug interact with Piolon 15 Tablet:
Co-administration of Ketoconazole and Piolon 15 Tablet, can increase the risk of side effects.

How to manage the interaction:
Taking Ketoconazole with Piolon 15 Tablet together can result in an interaction, it can be taken if a doctor has advised it. However, consult the doctor, if you experience any unusual symptoms. Do not discontinue any medications without a doctor's advice.
PioglitazoneTeriflunomide
Severe
How does the drug interact with Piolon 15 Tablet:
Co-administration of Teriflunomide and Piolon 15 Tablet may increase the risk of liver damage.

How to manage the interaction:
Although taking Piolon 15 Tablet and Teriflunomide together can possibly result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, nausea, vomiting, dark urine, light stools, and skin or eye yellowing, decreased hunger, consult the doctor. Do not stop using any medications without talking to the doctor.
PioglitazoneGemfibrozil
Severe
How does the drug interact with Piolon 15 Tablet:
When Piolon 15 Tablet is taken with Gemfibrozil, the level of Piolon 15 Tablet in the blood can go up. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Piolon 15 Tablet with Gemfibrozil together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you experience visual abnormalities, excessive or quick weight gain, swelling in the ankles or legs, trouble breathing, unusual fatigue, chest discomfort or tightness, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark coloured urine, light coloured stools, or yellowing of the skin or eyes, seek medical attention immediately. Do not discontinue any medications without consulting a doctor.
PioglitazoneClopidogrel
Severe
How does the drug interact with Piolon 15 Tablet:
Taking Piolon 15 Tablet with Clopidogrel can increases the blood levels of Piolon 15 Tablet, when these medicines are taken together, you may experience hypoglycemia (low blood sugar).

How to manage the interaction:
Taking Clopidogrel together with Piolon 15 Tablet may lead to interaction, but it can be taken if prescribed by your doctor. Consult a doctor immediately if you experience headache, dizziness, drowsiness, nervousness, weakness, shaking, or sweating. Do not discontinue any medication without consulting the doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Fill your half plate with starchy veggies, a quarter with proteins, and a quarter with whole grain.

  • Eat at regular interval. Do not take the long gap between a meal or snack.

  • Monitor your blood sugar level regularly especially when there are a lot of fluctuations.

  • Invest at least 150 min of moderate-intensity physical activity and 15 minutes of high-intensity exercise every week.

  • Lose weight gradually to achieve a healthy body mass index (18.5 to 24.9).

  • Replace refined carbohydrates containing foods with whole grain foods and increase intake of fruits and veggies and other fibre enriched foods.

  • Reduce intake of saturated fat (or hidden fats) in the food like chips, crisps, pastries, biscuits and samosas. Choose omega 3 fatty acid-containing oils for daily cooking. For frying, you may use palm oil, mustard oil, groundnut oil, rice bran oil, and safflower oil.

  • Do not take stress as it may elevate your blood sugar level. You may adopt stress management techniques like mindfulness, yoga or meditation to control stress-related to blood sugar changes.

  • Opt for low-fat dairy products (low-fat yoghurt, fat-free milk and cheese etc.).

  • Keep your blood pressure as normal (120/80) as possible. As it reduces the risk of cardiovascular diseases in diabetes patients.

Habit Forming

No

Therapeutic Class

ANTIDIABETICS

Piolon 15mg Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

You are recommended not to consume alcohol along with Piolon 15mg Tablet to avoid unpleasant side-effects.

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Pregnancy

Unsafe

Piolon 15mg Tablet is not generally recommended in pregnancy. It's not clear whether pioglitazone can harm your unborn baby. It is highly recommended to consult your doctor before taking this drug in case you are pregnant.

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Breast Feeding

Caution

It is highly recommended to consult your doctor before taking Piolon 15mg Tablet .

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Driving

Caution

Piolon 15mg Tablet will not affect your ability to drive or use machines but take care if you experience abnormal vision.

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Liver

Caution

Piolon 15mg Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

bannner image

Kidney

Caution

Piolon 15mg Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

bannner image

Children

Unsafe

The safety and efficacy of Piolon 15mg Tablet in children have not been established. Piolon 15mg Tablet is not recommended in children.

Have a query?

FAQs

Piolon 15mg Tablet is used to treat type 2 (non-insulin-dependent) diabetes mellitus. It helps control the sugar level in your blood by helping your body make better use of the insulin it produces.

Type-2 diabetes generally does not affect healthy children and teens, but it may affect children who are obese, which is also known as Childhood Obesity.

Hypoglycemia refers to low blood sugar levels, and it is one of the side effects of Piolon 15mg Tablet . Hypoglycemia can occur if you miss or delay your food, drink alcohol, over-exercise or take other antidiabetic medicine along with this medicine. It is important to monitor blood sugar levels regularly.

If you have symptoms like increased hunger, increased thirst, frequent urination (usually at night), unexplained weight loss, fatigue, blurred vision, slow wound/sores healing, and frequent infections, contact doctor as it can be a condition of type 2 diabetes.

In case you feel that your blood sugar level is going down and you are feeling weak, immediately eat sugar candies or drink sugary beverages. It will help to balance the blood sugar level in your body. So, it is advisable to keep sugar candies with you.

If you have or have ever had urinary bladder cancer, diabetic eye disease (retinopathy), or kidney or liver disease, avoid use of Piolon 15mg Tablet . If it is urgent consult with the doctor.

Swallow the tablet whole with a drink of water. Do not chew it. Piolon 15mg Tablet can be taken with or without food.

The safety and efficacy of Piolon 15mg Tablet in children under 18 years have not been established, so it should not be given to them.

Piolon 15mg Tablet contains Pioglitazone, which helps control the sugar level in your blood when you have type 2 diabetes by helping your body make better use of the insulin it produces.

The most common side effects of Piolon 15mg Tablet are upper respiratory tract infection, headache, sinusitis, myalgia (muscle pain), and pharyngitis. Most of these side effects of Piolon 15mg Tablet do not require medical attention and gradually resolve over time. Please consult your doctor if these side effects become troublesome.

You can take Piolon 15mg Tablet at any time with or without food, for example, in the morning or the evening. Try to take it at the same time every day.

Some people increase body fat after using pioglitazone. This can make them gain weight. To avoid gaining too much weight, try to eat a healthy balanced diet while keeping your portion sizes consistent. Regular exercise will also help to maintain your weight.

Pioglitazone-induced heart failure is known in patients with underlying heart disease but is not well documented in patients with normal. Please discuss with your doctor if you have underlying heart disease before taking Piolon 15mg Tablet .

Yes, Piolon 15mg Tablet and metformin combination is used with proper diet and exercise to treat high blood sugar levels caused by type 2 diabetes.

You can take Piolon 15mg Tablet at any time with or without food, for example, in the morning or the evening. Try to take it at the same time every day.

Piolon 15mg Tablet is used to treat diabetes. Diabetes therapy is usually lifelong. Do not discontinue taking pioglitazone without consulting your doctor. If you stop taking pioglitazone suddenly, your blood sugar levels can drop. If you want to discontinue taking your medication, consult your doctor. They may be able to recommend an alternative treatment for your diabetes.

Patients should avoid self-discontinuing diabetes medication when symptoms improve because symptoms may not reflect the actual condition. Doing so is very dangerous, not controlling blood sugar and making complications appear early. However, a person can stop using this drug safely if they can effectively manage their Type 2 diabetes mellitus (T2DM) through sustainable lifestyle changes. Please discuss this with your doctor for personalized guidance.

Piolon 15mg Tablet is usually safe to take for a long time. Your doctor will give you regular tests to check whether it's OK for you to continue taking it.

Piolon 15mg Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor. So, let your doctor know about your medical condition.

Piolon 15mg Tablet is an anti-diabetic medicine belonging to the class of thiazolidinedione (TZD), also called glitazones, used to treat type 2 (non-insulin-dependent) diabetes mellitus.

Pioglitazone, a thiazolidinedione, improves glycemic control in type 2 diabetics by enhancing peripheral insulin sensitivity, whereas metformin, a biguanide, works mostly by lowering hepatic glucose production.

Pioglitazone may raise bladder cancer risk in a dose- and time-dependent way, according to current research. Patients with long-term and high-dose pioglitazone exposure should be frequently examined for bladder cancer.

Piolon 15mg Tablet may be used alone or with other medicines, such as insulin, metformin, or sulfonylurea agents. Before using Piolon 15mg Tablet along with other medications, check with your doctor. The doctor will check for potential interactions and guide you through the process of taking them if necessary.

To avoid potential interactions and minimise side effects, before using this medication, you should inform your doctor about your medical history, including any ongoing medicines.

Pioglitazone is not suggested during pregnancy because there is limited information on its safety. If you are pregnant or planning to become pregnant, consult your doctor, as they will need to reassess your treatment. They will be able to recommend a different prescription that is safe for you to take throughout pregnancy.

Store in a cool and dry place away from sunlight. Keep out of sight and reach of children.

Country of origin

India

Manufacturer/Marketer address

M-17, Pharma Tower, Basement & Ground Floor, Badli Industrial Area, New Delhi 110 042
Other Info - PIO0206

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jan 1, 2025 | 2:49 PM IST

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Reference

  1. https://www.nhs.uk/medicines/pioglitazone/
  2. https://www.medicines.org.uk/emc/files/pil.4731.pdf
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