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  3. Piozone 30 mg Tablet 10's

Piozone 30 mg Tablet 10's, Pack of 10 TabletS
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Piozone 30 mg Tablet is used to treat type 2 (non-insulin-dependent) diabetes mellitus. It contains Pioglitazone, which helps control the sugar level in your blood when you have type 2 diabetes by helping your body make better use of the insulin it produces. It may cause common side effects such as upper respiratory tract infection, headache, sinusitis, myalgia (muscle pain), and pharyngitis. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

PIOGLITAZONE-30MG

Manufacturer/Marketer :

Abbott India Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Piozone 30 mg Tablet

Piozone 30 mg Tablet is an anti-diabetic medicine used to treat type 2 diabetes mellitus. Type 2 diabetes is an illness where the body doesn't make enough insulin, or the insulin that it makes doesn't work properly. This is diabetes that usually develops in adulthood.

Piozone 30 mg Tablet contains pioglitazone, which helps control the sugar level in your blood when you have type 2 diabetes by helping your body make better use of the insulin it produces.

The most common side effects of Piozone 30 mg Tablet are upper respiratory tract infection, headache, sinusitis, myalgia (muscle pain), and pharyngitis. Most of these side effects of Piozone 30 mg Tablet do not require medical attention and gradually resolve over time. Please consult your doctor if these side effects become troublesome.

Piozone 30 mg Tablet should not be stopped even if you feel better without consulting your doctor. Please inform your doctor if you have any heart disease, are or are planning to get pregnant or are breastfeeding. The safety and efficacy of Piozone 30 mg Tablet in children under 18 years have not been established, so it should not be given to them.

Uses of Piozone 30 mg Tablet

Piozone 30 mg Tablet is used in the treatment of Type 2 diabetes mellitus. The detailed uses of Piozone 30 mg Tablet are as follows:

  • Type 2 Diabetes Mellitus: Piozone 30 mg Tablet helps control blood sugar levels when diet, exercise, and other medications aren’t enough.
  • Insulin Resistance: Piozone 30 mg Tablet enhances the body’s response to insulin, reducing insulin resistance in muscle, fat, and liver cells.

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Directions for Use

  • Take Piozone 30 mg Tablet with or without food as advised by your doctor.
  • It is advised to take Piozone 30 mg Tablet once daily; however, follow your doctor’s recommendation regarding the dosage and duration.
  • Swallow Piozone 30 mg Tablet as a whole with a glass of water.
  • Do not crush, chew, or break it.

Medicinal Benefits

  • Piozone 30 mg Tablet is an antidiabetic drug (thiazolidinedione/glitazones) used along with a proper diet and exercise to control high blood sugar (hyperglycaemia) in patients with type 2 diabetes.
  • Piozone 30 mg Tablet works by helping to restore your body's appropriate response to insulin, thereby lowering your blood sugar.

How Piozone 30 mg Tablet Works

Piozone 30 mg Tablet contains Pioglitazone, which helps control the sugar level in your blood when you have type 2 diabetes by helping your body make better use of the insulin it produces.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Piozone 30 mg Tablet
  • If you experience low blood sugar levels, inform your doctor. They will assess the severity and make recommendations for the next actions.
  • Your doctor will assess your symptoms, blood sugar levels, and overall health before recommending the best course of action, which may include treatment, lifestyle modifications, or prescription adjustments.
  • Follow your doctor's instructions carefully to manage the episode and adjust your treatment plan.
  • Make medication adjustments as recommended by your doctor to prevent future episodes.
  • Implement diet and lifestyle modifications as your doctor advises to manage low blood sugar levels.
  • Monitor your blood sugar levels closely for patterns and changes.
  • Track your progress by recording your blood sugar levels, food intake, and physical activity.
  • Seek further guidance from your doctor if symptoms persist or worsen so that your treatment plan can be revised.
  • Eat fiber-rich foods, fruits, and vegetables, and track your food intake to monitor calorie consumption.
  • Limit takeout and restaurant meals, and weigh yourself weekly to stay motivated.
  • Build balanced meals, allow yourself to enjoy treats in moderation, and prioritize sleep and stress management through exercise and relaxation techniques.
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.
  • Heart failure needs immediate medical attention. To manage this effect, the doctor's instructions must be followed strictly.
  • Take care of change in your weight as there can be sudden changes.
  • Rest and refrain from physical activity, and restart after a few days.
  • Reduce your salt intake and control your diet with the help of a dietician.
  • Track your symptoms and keep your follow-up appointments to manage severe side effects.
  • Heart failure needs immediate medical attention. To manage this effect, the doctor's instructions must be followed strictly.
  • Take care of change in your weight as there can be sudden changes.
  • Rest and refrain from physical activity, and restart after a few days.
  • Reduce your salt intake and control your diet with the help of a dietician.
  • Track your symptoms and keep your follow-up appointments to manage severe side effects.
  • Chest pain may last for a while and needs immediate medical attention as it is a significant health issue to be attended to.
  • Take rest and refrain from doing physical activity for a while, and restart after a few days.
  • Try applying an ice pack to the strained area for at least 20 minutes thrice a day. Ice pack thus helps reduce inflammation.
  • Sit upright and maintain proper posture if there is persistent chest pain. • Use extra pillows to elevate your position and prop your chest up while sleeping.

What if I have taken an overdose of Piozone 30 mg Tablet

Do not take more than the prescribed dose of Piozone 30 mg Tablet as it may cause overdose resulting in low blood sugar. The symptoms include sweating, tremors, stomach pain, extreme weakness, blurred vision, trouble speaking, seizures (fits) and confusion. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

  • Fluid retention (oedema) may occur and can lead to congestive heart failure so, a combination of use with insulin and use in heart failure may increase the risk in patients taking Piozone 30 mg Tablet .
  • You should not take Piozone 30 mg Tablet if you have kidney disease, as measured by a blood test.
  • Piozone 30 mg Tablet , when used with or without insulin, Piozone 30 mg Tablet tends to lower the blood sugar level. So, the doctor may lower the dose of insulin.
  • Increased fractures may be reported in some women taking Piozone 30 mg Tablet .
  • Patients with bladder cancer and macular oedema (fluid build-up in the macula part of the retina of the eye) should consult the doctor before using Piozone 30 mg Tablet .
  • Before the doctor prescribes this medicine, it is always better that your physician knows about any underlying conditions like kidney or liver disease, prior heart attack, alcohol intake, etc.
  • Avoid drinking alcohol while on this drug as it increases the risk of hypoglycaemia (a decrease in blood sugar, which might be fatal in some cases) and lactic acidosis (when the lactic acid increases in the body, which impacts the functioning of various organs in the body).
  • Try to quit smoking and reduce your intake of carbohydrate-rich foods like potatoes, rice, mangoes, bread, sugar, etc.
  • Take short, frequent meals, and avoid prolonged fasting when taking this drug.
  • Beware of symptoms of hypoglycaemia, which include sweating, dizziness, palpitations, shivering, intense thirst, dry mouth, dry skin, frequent urination, etc.
  • Whenever you experience the symptoms mentioned above, immediately consume 5-6 candies, three glucose biscuits, or three teaspoons of honey/sugar and get in touch with your physician. Make sure to carry these with you at all times, especially for long travels. 

Drug-Drug Interactions

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PioglitazoneGatifloxacin
Critical
PioglitazoneTeriflunomide
Severe

Drug-Drug Interactions

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PioglitazoneGatifloxacin
Critical
How does the drug interact with Piozone 30 mg Tablet:
Co-administration of Piozone 30 mg Tablet with Gatifloxacin may sometimes affect blood glucose levels. Both high blood glucose and, less frequently, low blood glucose have been reported.

How to manage the interaction:
Although there is a possible interaction, Piozone 30 mg Tablet can be taken with Gatifloxacin if prescribed by the doctor. Consult the prescriber if you experience symptoms such as nervousness, confusion, headache, dizziness, drowsiness, tremors, nausea, hunger, weakness, excessive sweating, rapid heartbeat, increased urination, increased thirst, and increased hunger. Maintaining blood glucose levels is advised. Do not discontinue any medications without a doctor's advice.
PioglitazoneTeriflunomide
Severe
How does the drug interact with Piozone 30 mg Tablet:
Co-administration of Teriflunomide and Piozone 30 mg Tablet may increase the risk of liver damage.

How to manage the interaction:
Although taking Piozone 30 mg Tablet and Teriflunomide together can possibly result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, nausea, vomiting, dark urine, light stools, and skin or eye yellowing, decreased hunger, consult the doctor. Do not stop using any medications without talking to the doctor.
PioglitazoneLeflunomide
Severe
How does the drug interact with Piozone 30 mg Tablet:
Co-administration of Piozone 30 mg Tablet and Leflunomide may increase the risk of liver damage.

How to manage the interaction:
Although taking Piozone 30 mg Tablet and Leflunomide together can possibly result in an interaction, it can be taken if a doctor has prescribed it. However, if you have any of the following symptoms: fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, fatigue, lack of appetite, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
PioglitazoneGemfibrozil
Severe
How does the drug interact with Piozone 30 mg Tablet:
When Piozone 30 mg Tablet is taken with Gemfibrozil, the level of Piozone 30 mg Tablet in the blood can go up. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Piozone 30 mg Tablet with Gemfibrozil together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you experience visual abnormalities, excessive or quick weight gain, swelling in the ankles or legs, trouble breathing, unusual fatigue, chest discomfort or tightness, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark coloured urine, light coloured stools, or yellowing of the skin or eyes, seek medical attention immediately. Do not discontinue any medications without consulting a doctor.
PioglitazoneMipomersen
Severe
How does the drug interact with Piozone 30 mg Tablet:
Co-administration of Mipomersen and Piozone 30 mg Tablet may increase the risk of liver damage.

How to manage the interaction:
Although taking Piozone 30 mg Tablet and Mipomersen together can possibly result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, nausea, vomiting, dark urine, light stools, and skin or eye yellowing, decreased hunger, consult the doctor. Do not stop using any medications without talking to the doctor.
PioglitazoneClopidogrel
Severe
How does the drug interact with Piozone 30 mg Tablet:
Taking Piozone 30 mg Tablet with Clopidogrel can increases the blood levels of Piozone 30 mg Tablet, when these medicines are taken together, you may experience hypoglycemia (low blood sugar).

How to manage the interaction:
Taking Clopidogrel together with Piozone 30 mg Tablet may lead to interaction, but it can be taken if prescribed by your doctor. Consult a doctor immediately if you experience headache, dizziness, drowsiness, nervousness, weakness, shaking, or sweating. Do not discontinue any medication without consulting the doctor.
PioglitazoneLomitapide
Severe
How does the drug interact with Piozone 30 mg Tablet:
Co-administration of Piozone 30 mg Tablet and Lomitapide may increase the risk of liver damage.

How to manage the interaction:
Although taking Lomitapide and Piozone 30 mg Tablet together can possibly result in an interaction, it can be taken if a doctor has prescribed it. However, if you have any of the following symptoms: fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, fatigue, lack of appetite, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
PioglitazoneKetoconazole
Severe
How does the drug interact with Piozone 30 mg Tablet:
Co-administration of Ketoconazole and Piozone 30 mg Tablet, can increase the risk of side effects.

How to manage the interaction:
Taking Ketoconazole with Piozone 30 mg Tablet together can result in an interaction, it can be taken if a doctor has advised it. However, consult the doctor, if you experience any unusual symptoms. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Fill your half plate with starchy veggies, a quarter with proteins, and a quarter with whole grains.
  • Eat at regular intervals. Do not take a long gap between meals or snacks.
  • Monitor your blood sugar level regularly, especially when there are a lot of fluctuations.
  • Invest at least 150 minutes of moderate-intensity physical activity and 15 minutes of high-intensity exercise every week.
  • Lose weight gradually to achieve a healthy body mass index (18.5 to 24.9).
  • Replace refined carbohydrate-containing foods with whole grain foods and increase intake of fruits and veggies and other fibre-enriched foods.
  • Reduce intake of saturated fat (or hidden fats) in foods like chips, crisps, pastries, biscuits and samosas. Choose omega-3 fatty acid-containing oils for daily cooking. For frying, you may use palm oil, mustard oil, groundnut oil, rice bran oil, and safflower oil.
  • Do not take stress as it may elevate your blood sugar level. You can adopt stress management techniques, such as mindfulness, yoga, or meditation, to help control stress related to blood sugar changes.
  • Opt for low-fat dairy products (low-fat yoghurt, fat-free milk and cheese, etc.).
  • Keep your blood pressure as normal (120/80) as possible. As it reduces the risk of cardiovascular diseases in diabetes patients.

Habit Forming

No

Therapeutic Class

ANTIDIABETICS

Piozone 30 mg Tablet Substitute

Substitutes safety advice
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Alcohol

Unsafe

You are recommended not to consume alcohol along with Piozone 30 mg Tablet to avoid unpleasant side-effects.

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Pregnancy

Unsafe

Piozone 30 mg Tablet is not generally recommended in pregnancy. It's not clear whether pioglitazone can harm your unborn baby. It is highly recommended to consult your doctor before taking this drug in case you are pregnant.

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Breast Feeding

Consult your doctor

It is highly recommended to consult your doctor before taking Piozone 30 mg Tablet .

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Driving

Caution

Piozone 30 mg Tablet will not affect your ability to drive or use machines but take care if you experience abnormal vision.

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Liver

Caution

Piozone 30 mg Tablet to be taken with caution, especially if you have a history of liver diseases/conditions.

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Kidney

Caution

Piozone 30 mg Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Unsafe

The safety and efficacy of Piozone 30 mg Tablet in children have not been established. Piozone 30 mg Tablet is not recommended in children.

FAQs

Piozone 30 mg Tablet is used to treat type 2 (non-insulin-dependent) diabetes mellitus. It helps control the sugar level in your blood by helping your body make better use of the insulin it produces.

Type-2 diabetes generally does not affect healthy children and teens, but it may affect children who are obese, which is also known as Childhood Obesity.

Hypoglycemia refers to low blood sugar levels, and it is one of the side effects of Piozone 30 mg Tablet . Hypoglycemia can occur if you miss or delay your food, drink alcohol, over-exercise or take other antidiabetic medicine along with this medicine. It is important to monitor blood sugar levels regularly.

If you have symptoms like increased hunger, increased thirst, frequent urination (usually at night), unexplained weight loss, fatigue, blurred vision, slow wound/sores healing, and frequent infections, contact doctor as it can be a condition of type 2 diabetes.

In case you feel that your blood sugar level is going down and you are feeling weak, immediately eat sugar candies or drink sugary beverages. It will help to balance the blood sugar level in your body. So, it is advisable to keep sugar candies with you.

If you have or have ever had urinary bladder cancer, diabetic eye disease (retinopathy), or kidney or liver disease, avoid use of Piozone 30 mg Tablet . If it is urgent consult with the doctor.

Swallow the tablet whole with a drink of water. Do not chew it. Piozone 30 mg Tablet can be taken with or without food.

The safety and efficacy of Piozone 30 mg Tablet in children under 18 years have not been established, so it should not be given to them.

Piozone 30 mg Tablet contains Pioglitazone, which helps control the sugar level in your blood when you have type 2 diabetes by helping your body make better use of the insulin it produces.

The most common side effects of Piozone 30 mg Tablet are upper respiratory tract infection, headache, sinusitis, myalgia (muscle pain), and pharyngitis. Most of these side effects of Piozone 30 mg Tablet do not require medical attention and gradually resolve over time. Please consult your doctor if these side effects become troublesome.

You can take Piozone 30 mg Tablet at any time with or without food, for example, in the morning or the evening. Try to take it at the same time every day.

Some people increase body fat after using pioglitazone. This can make them gain weight. To avoid gaining too much weight, try to eat a healthy balanced diet while keeping your portion sizes consistent. Regular exercise will also help to maintain your weight.

Pioglitazone-induced heart failure is known in patients with underlying heart disease but is not well documented in patients with normal. Please discuss with your doctor if you have underlying heart disease before taking Piozone 30 mg Tablet .

Yes, Piozone 30 mg Tablet and metformin combination is used with proper diet and exercise to treat high blood sugar levels caused by type 2 diabetes.

You can take Piozone 30 mg Tablet at any time with or without food, for example, in the morning or the evening. Try to take it at the same time every day.

Piozone 30 mg Tablet is used to treat diabetes. Diabetes therapy is usually lifelong. Do not discontinue taking pioglitazone without consulting your doctor. If you stop taking pioglitazone suddenly, your blood sugar levels can drop. If you want to discontinue taking your medication, consult your doctor. They may be able to recommend an alternative treatment for your diabetes.

Patients should avoid self-discontinuing diabetes medication when symptoms improve because symptoms may not reflect the actual condition. Doing so is very dangerous, not controlling blood sugar and making complications appear early. However, a person can stop using this drug safely if they can effectively manage their Type 2 diabetes mellitus (T2DM) through sustainable lifestyle changes. Please discuss this with your doctor for personalized guidance.

Piozone 30 mg Tablet is usually safe to take for a long time. Your doctor will give you regular tests to check whether it's OK for you to continue taking it.

Piozone 30 mg Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor. So, let your doctor know about your medical condition.

Piozone 30 mg Tablet is an anti-diabetic medicine belonging to the class of thiazolidinedione (TZD), also called glitazones, used to treat type 2 (non-insulin-dependent) diabetes mellitus.

Pioglitazone, a thiazolidinedione, improves glycemic control in type 2 diabetics by enhancing peripheral insulin sensitivity, whereas metformin, a biguanide, works mostly by lowering hepatic glucose production.

Pioglitazone may raise bladder cancer risk in a dose- and time-dependent way, according to current research. Patients with long-term and high-dose pioglitazone exposure should be frequently examined for bladder cancer.

Piozone 30 mg Tablet may be used alone or with other medicines, such as insulin, metformin, or sulfonylurea agents. Before using Piozone 30 mg Tablet along with other medications, check with your doctor. The doctor will check for potential interactions and guide you through the process of taking them if necessary.

To avoid potential interactions and minimise side effects, before using this medication, you should inform your doctor about your medical history, including any ongoing medicines.

Pioglitazone is not suggested during pregnancy because there is limited information on its safety. If you are pregnant or planning to become pregnant, consult your doctor, as they will need to reassess your treatment. They will be able to recommend a different prescription that is safe for you to take throughout pregnancy.

Store in a cool and dry place away from sunlight. Keep out of sight and reach of children.

Country of origin

India

Manufacturer/Marketer address

401, LSC, C-Block, Mohan Place Saraswati Vihar Delhi DL 110034 In.
Other Info - PIO0023

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Sep 15, 2025 | 12:55 PM IST

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Reference

  1. https://www.nhs.uk/medicines/pioglitazone/
  2. https://www.medicines.org.uk/emc/files/pil.4731.pdf

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