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  3. PIROEVER TABLET

PIROEVER TABLET, Pack of 10 TabletS
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

PIROEVER TABLET is used to relieve symptoms like pain, inflammation, and joint stiffness associated with rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. It contains Piroxicam, which stops the production of prostaglandins (chemicals) that are produced at injury sites and cause pain and swelling. In some cases, you may experience common side effects, such as diarrhoea, stomach upset, headache, dizziness, ringing in the ears, heartburn, nausea, vomiting, and constipation. Before taking this medicine, inform your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and any pre-existing medical conditions.

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Composition :

PIROXICAM-20MG

Manufacturer/Marketer :

Akumentis Healthcare Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About PIROEVER TABLET

PIROEVER TABLET belongs to a group of medications called 'Nonsteroidal Anti-inflammatory Drugs (NSAIDs),' used to relieve symptoms like pain, inflammation, and joint stiffness associated with rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. Osteoarthritis is a degenerative joint disease caused by the breakdown of cartilage (a protective covering) and the underlying bone. Rheumatoid arthritis is an autoimmune disease (the body's immune system attacks its tissue), leading to joint pain and damage. Ankylosing spondylitis is a chronic inflammatory condition that causes stiffness and fusion of the spinal bones (vertebrae).

PIROEVER TABLET contains Piroxicam, which works by blocking the effect of a chemical messenger in the body, known as cyclooxygenase (COX) enzymes, that produce another chemical, prostaglandins. Prostaglandins are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, fewer prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

Take PIROEVER TABLET exactly as prescribed. Your doctor will decide the dosage and timing of this medication based on your medical condition. In some cases, you may experience common side effects, such as diarrhoea, stomach upset, headache, dizziness, ringing in the ears, heartburn, nausea, vomiting, and constipation. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to speak to your doctor if you experience these side effects persistently.

Do not take PIROEVER TABLET if you are allergic to any of its ingredients or have a history of an asthma attack or severe allergic reaction to NSAIDs. PIROEVER TABLET can increase your risk of a fatal heart attack or stroke. So, if you have had any recent heart bypass surgery, do not take PIROEVER TABLET unless prescribed by the doctor. PIROEVER TABLET increases the chances of stomach ulcers and bleeding, especially in elderly patients. Consult your doctor before taking PIROEVER TABLET if you are pregnant or planning to become pregnant. Avoid breastfeeding while taking PIROEVER TABLET, as it can pass into breast milk. PIROEVER TABLET is not recommended for children under 18 years, as its safety and efficacy have not been established. PIROEVER TABLET may cause drowsiness, dizziness, and vision problems, so drive with caution. Avoid consuming alcohol along with PIROEVER TABLET, as it could lead to increased dizziness and drowsiness.

Uses of PIROEVER TABLET

PIROEVER TABLET is used in the treatment of joint pain and inflammation associated with various conditions. The detailed uses of PIROEVER TABLET are as follows:

  • Rheumatoid Arthritis: It helps reduce inflammation and joint damage caused by autoimmune activity.
  • Osteoarthritis: It helps relieve joint pain, inflammation, and stiffness caused by cartilage wear and tear.
  • Ankylosing Spondylitis: It helps alleviate spinal pain and stiffness associated with this chronic inflammatory disease.
  • Menstrual Pain (Dysmenorrhea) Management: It can effectively relieve pain caused by menstrual cramps, providing comfort during menstruation (periods).
  • Postoperative Pain Management: It is often prescribed for the short-term management of pain and inflammation following surgical procedures.

Directions for Use

  • PIROEVER TABLET can be taken with or without food. However, taking it after food may help reduce stomach upset. 
  • It is usually taken 1-2 times daily at the same time each day or as prescribed by your doctor.
  • Swallow it as a whole with a glass of water.
  • Do not crush, chew, break, or open the medication.

Medicinal Benefits

PIROEVER TABLET belongs to the group of painkillers known as NSAIDs (Non-Steroidal Anti-Inflammatory Drugs). PIROEVER TABLET is used to relieve symptoms associated with rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis, such as stiffness, swelling, and joint pain. PIROEVER TABLET contains Piroxicam, which works by blocking the effect of a chemical messenger in the body, known as cyclooxygenase (COX) enzymes, that produce another chemical, prostaglandins. Prostaglandins are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, fewer prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

How PIROEVER TABLET Works

PIROEVER TABLET contains Piroxicam, which works by blocking the effect of a chemical messenger in the body, known as cyclooxygenase (COX) enzymes, that produce another chemical, prostaglandins. Prostaglandins are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, fewer prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Piroever Tablet
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Get help from a health care professional.
  • Manage your feelings and things that trigger them.
  • Fuel your body with good food like fruits, veggies, and whole grains.
  • Find calm through activities like meditation or yoga.
  • Work on changing negative patterns and thoughts.
  • Focus on being healthy overall, not just how you look.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
  • If you experience or encounter any severe allergic reaction, stop using medication and consult the doctor right away.
  • Tell your doctor about the allergic reaction, including the medication taken and any symptoms experienced.
  • Your doctor will evaluate the severity of the reaction and determine the best course of action.
  • To ensure a full recovery, follow your doctor's advice, attend scheduled follow-up appointments, and undergo recommended tests to monitor progress and adjust treatment as needed.

What if I have taken an overdose of PIROEVER TABLET

Do not take more than the prescribed dose of PIROEVER TABLET, as it may cause an overdose. The symptoms of an overdose include drowsiness, lack of energy, vomiting, stomach upset, bloody/black/tarry stools, stomach pain, difficulty breathing, or coma. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take PIROEVER TABLET if you are allergic to any of its ingredients or have a history of an asthma attack or severe allergic reaction to NSAIDs. PIROEVER TABLET may increase the risk of serious heart-related problems, like heart attack and stroke. It may also cause stomach and intestinal bleeding/ulcers. So, inform your doctor if you have any heart or stomach problems before taking PIROEVER TABLET. Avoid taking PIROEVER TABLET if you have had heart bypass surgery or coronary artery bypass graft surgery (CABG), as it can increase your risk of a heart attack or stroke. Consult your doctor before taking PIROEVER TABLET if you are pregnant or planning to become pregnant. Avoid breastfeeding while taking PIROEVER TABLET, as it can pass into breast milk. PIROEVER TABLET is not recommended for children under 18 years, as its safety and efficacy have not been established. PIROEVER TABLET may cause drowsiness, dizziness, and vision problems, so drive with caution. Avoid consuming alcohol along with PIROEVER TABLET, as it may increase drowsiness and the risk of stomach bleeding. Inform your doctor before taking PIROEVER TABLET if you have asthma, water retention (oedema), hypertension (high blood pressure), diabetes (high blood sugar), high cholesterol, blood clots, or liver/kidney disease.

Drug-Drug Interactions

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PiroxicamKetorolac tromethamine
Critical
PiroxicamCidofovir
Critical

Drug-Drug Interactions

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PiroxicamKetorolac tromethamine
Critical
How does the drug interact with Piroever Tablet:
Using ketorolac tromethamine together with Piroever Tablet may increase the risk of side effects.

How to manage the interaction:
Taking Piroever Tablet with Ketorolac tromethamine is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. Consult a doctor if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop using any medications without talking to a doctor.
PiroxicamCidofovir
Critical
How does the drug interact with Piroever Tablet:
Co-administration of Cidofovir with Piroever Tablet can increase the risk of kidney problems.

How to manage the interaction:
Taking Piroever Tablet with Cidofovir is not recommended as it can cause an interaction, it can be taken together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
PiroxicamIbuprofen
Severe
How does the drug interact with Piroever Tablet:
Use of Piroever Tablet with Ibuprofen can increase the risk of side effects such as inflammation(swelling with redness and pain), bleeding, ulceration.

How to manage the interaction:
Co-administration of Piroever Tablet and Ibuprofen can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
PiroxicamEdoxaban
Severe
How does the drug interact with Piroever Tablet:
Coadministration of Piroever Tablet with Edoxaban can increase the risk of bleeding.

How to manage the interaction:
Taking Piroever Tablet with Edoxaban together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
PiroxicamFlurbiprofen
Severe
How does the drug interact with Piroever Tablet:
Using Piroever Tablet together with flurbiprofen may increase the risk of side effects such as inflammation(swelling with redness and pain), bleeding and ulceration.

How to manage the interaction:
Although there is a possible interaction between Flurbiprofen and Piroever Tablet, it can be taken if your doctor has advised it. However, if you experience dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
PiroxicamDicoumarol
Severe
How does the drug interact with Piroever Tablet:
Coadministration of Piroever Tablet with Dicoumarol can increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between Piroever Tablet and Dicoumarol, you can take these medicines together if prescribed by a doctor. However, if you experience unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor. Do not stop using any medications without talking to a doctor.
PiroxicamIodamide
Severe
How does the drug interact with Piroever Tablet:
Coadministration of Piroever Tablet and Iodamide can increase the risk of kidney problems.

How to manage the interaction:
Although taking Piroever Tablet and Iodamide together can cause an interaction, it can be taken if your doctor has suggested it. However, consult a doctor if experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, swelling, breathing difficulty, muscle cramps, tiredness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without a doctor's advice.
PiroxicamKetorolac
Severe
How does the drug interact with Piroever Tablet:
Using ketorolac together with Piroever Tablet may increase the risk of side effects such as inflammation(swelling with redness and pain), bleeding, ulceration.

How to manage the interaction:
Although taking Ketorolac and Piroever Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without talking to a doctor.
PiroxicamAcalabrutinib
Severe
How does the drug interact with Piroever Tablet:
Using acalabrutinib together with Piroever Tablet may increase the risk of bleeding.

How to manage the interaction:
Although taking Piroever Tablet and Acalabrutinib together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not discontinue any medications without consulting a doctor.
PiroxicamSirolimus
Severe
How does the drug interact with Piroever Tablet:
Co-administration of Sirolimus with Piroever Tablet can increase the risk or severity of kidney damage.

How to manage the interaction:
Co-administration of Sirolimus with Piroever Tablet can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not stop using any medication without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Physical activity helps strengthen muscles and relieve joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help improve joint flexibility and pain.
  • Maintain a healthy weight by engaging in regular low-impact exercises and consuming a balanced diet.
  • Get adequate sleep, as rest can help reduce inflammation and swelling.
  • Follow heat or cold therapy, apply a cold or hot compress on the joints for 15-20minutes regularly.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath, or listening to soothing music.
  • Acupuncture, massage, and physical therapy may also be helpful.
  • Eat foods rich in antioxidants, such as berries, spinach, kidney beans, and dark chocolate.
  • Foods containing flavonoids can help reduce inflammation. These include soy, berries, broccoli, grapes, and green tea.
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

ANALGESICS

PIROEVER TABLET Substitute

Substitutes safety advice

Product Substitutes

bannner image

Alcohol

Unsafe

Avoid alcohol consumption while taking PIROEVER TABLET, as it may cause increased dizziness and drowsiness. It may also cause an increase in the risk of stomach/intestinal ulcers and bleeding.

bannner image

Pregnancy

Caution

Avoid taking PIROEVER TABLET if you are pregnant unless prescribed by the doctor. Please consult your doctor if you have any concerns regarding this; your doctor will prescribe PIROEVER TABLET only if the benefits outweigh the risks. Do not take PIROEVER TABLET in the last 20 weeks of pregnancy, as it may cause serious kidney and heart problems in the unborn baby and complications with the pregnancy.

bannner image

Breast Feeding

Unsafe

PIROEVER TABLET can pass into breast milk. So, avoid breastfeeding while taking PIROEVER TABLET. Please consult your doctor if you have any concerns regarding this.

bannner image

Driving

Unsafe

PIROEVER TABLET may cause drowsiness, dizziness, and vision problems. Do not drive or operate heavy machinery unless you are alert.

bannner image

Liver

Caution

Dose adjustment may be needed. PIROEVER TABLET should be used with caution in patients with liver impairment/liver disease. Please consult your doctor if you have a liver impairment or any concerns regarding this.

bannner image

Kidney

Caution

Dose adjustment may be needed. PIROEVER TABLET should be used with caution in patients with kidney impairment/kidney disease. Please consult your doctor if you have a kidney impairment or any concerns regarding this.

bannner image

Children

Unsafe

PIROEVER TABLET is not recommended for children under 18 years, as its efficacy and safety have not been established.

Have a query?

FAQs

PIROEVER TABLET is used to relieve symptoms like pain, inflammation, and joint stiffness associated with rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis.

PIROEVER TABLET works by blocking the effect of chemical messengers (prostaglandin), thereby reducing joint pain, stiffness, swelling, and inflammation.

Diarrhoea might be a side effect of PIROEVER TABLET. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

Do not take PIROEVER TABLET for longer durations or high doses as it may cause unpleasant side effects. Do not exceed the dose and duration prescribed by your doctor.

PIROEVER TABLET may increase the risk of heart attack or stroke. Do not use PIROEVER TABLET immediately before or after bypass surgery. Inform your doctor if you have a history of heart disease or other heart problems.

Consult your doctor before taking PIROEVER TABLET if you have diabetes, as PIROEVER TABLET might increase your blood sugar levels.

The common side effects of PIROEVER TABLET are diarrhoea, stomach upset, headache, dizziness, ringing in the ears, heartburn, nausea, vomiting, and constipation. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to speak to your doctor if you experience these side effects persistently.

Country of origin

India

Manufacturer/Marketer address

204, 2nd Floor, G-Corp Tech Park, Kasarvadavali, Near Hypercity, Ghodbandar Road, Thane (West) - 400615. ,Maharashtra, India
Other Info - PIR0104

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 23, 2025 | 8:22 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2006/018147s029lbl.pdf
  2. https://www.nafdac.gov.ng/wp-content/uploads/Files/SMPC/a_v7/SmPc-PIROXICAM.pdf
  3. https://www.medicines.org.uk/emc/files/pil.14311.pdf
  4. https://www.drugs.com/mtm/piroxicam.html
  5. https://medlineplus.gov/druginfo/meds/a684045.html
  6. https://www.medindia.net/doctors/drug_information/piroxicam.htm

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