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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Planep T 20 mg Tablet is a combination medicine used in the treatment of Oedema (swelling) and hypertension (high blood pressure). This medicine contains eplerenone and torsemide, which works by reducing the excess fluid levels in the body and thus reduces swelling. Common side effects include dehydration, electrolyte disturbances (calcium, magnesium, and sodium), constipation, increased uric acid and itching.

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Manufacturer/Marketer :

Lupin Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Planep T 20 mg Tablet

Planep T 20 mg Tablet is used to remove excess water from the body. It also maintains the bloodstream's potassium level and prevents hypertension (high blood pressure) due to Oedema (fluid retention). Oedema or fluid overload is associated with pulmonary hypertension (high blood pressure in the lung) or heart failure (irregular heart pumping). Leg swelling is the main characteristic of Oedema, accompanied by shortness of breath, chest pain (angina), abnormal heart rhythms (arrhythmia) and swelling in other areas of the hands or abdomen.

Planep T 20 mg Tablet is a combination of medications containing Eplerenone and Torsemide, which are prescribed for the treatment of resistant Oedema (fluid overload) associated with pulmonary hypertension (high blood pressure in the lungs), heart failure and hepatic cirrhosis (chronic liver damage). Planep T 20 mg Tablet works by increasing the amount of urine passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney or lung disease. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, it also helps lower high blood pressure, reducing the chances of any future heart attack, stroke or angina (chest pain).

Take Planep T 20 mg Tablet as prescribed by your doctor. You are advised to take Planep T 20 mg Tablet for as long as your doctor has prescribed it. In some cases, you may experience dehydration, electrolyte disturbances (calcium, magnesium, and sodium), constipation, increased uric acid and itching. Most of these side effects of Planep T 20 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist, contact your doctor.

Try not to stop taking Planep T 20 mg Tablet of your own, as doing so may raise your blood pressure, thereby increasing the risk of getting a heart attack and stroke. Inform your doctor if you suffer from any kidney, liver or heart disease. If you are pregnant or breastfeeding, please tell your doctor so that the dosage of Planep T 20 mg Tablet can be prescribed accordingly. Please tell your doctor if you are taking other medicines or are allergic to Planep T 20 mg Tablet . Reducing the amount of table salt (sodium chloride) in your food often relieves the body's swelling.

Uses of Planep T 20 mg Tablet

Planep T 20 mg Tablet is used in the treatment of oedema (swelling) and hypertension (high blood pressure). The detailed uses of Planep T 20 mg Tablet are as follows:<br/>• Treatment of Oedema (Swelling): It helps remove excess fluid from the body, reducing swelling in areas like the legs, feet, and ankles.<br/>• Treatment of Hypertension (High Blood Pressure): It lowers blood pressure by eliminating extra fluid and easing the workload on the heart.<br/>

Directions for Use

  • Planep T 20 mg Tablet can be taken orally with or without food, or as directed by your physician.
  • It is best to avoid taking this medication within 4 hours of your bedtime to prevent having to get up to urinate.
  • Swallow the tablet whole with a full glass of water; do not crush, chew, or break it.

Medicinal Benefits

Planep T 20 mg Tablet is primarily used to remove excess water from the body. It also maintains the bloodstream's potassium level and prevents hypertension (high blood pressure) due to Oedema (fluid retention). Planep T 20 mg Tablet is a combination of medications containing Eplerenone and Torsemide. Both Eplerenone and Torsemide are diuretics and are prescribed for the treatment of resistant Oedema (fluid overload) associated with pulmonary hypertension (high blood pressure in the lungs), heart failure and hepatic cirrhosis (chronic liver damage). Planep T 20 mg Tablet works by increasing the amount of urine passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats Oedema (swelling) associated with heart, liver, kidney or lung disease. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, it also helps lower high blood pressure, reducing the chances of any future heart attack, stroke or angina (chest pain).

How Planep T 20 mg Tablet Works

Planep T 20 mg Tablet is a combination of medications containing Eplerenone and Torsemide, which are prescribed for the treatment of resistant Oedema (fluid overload) associated with pulmonary hypertension (high blood pressure in the lungs), heart failure and hepatic cirrhosis (chronic liver damage). Planep T 20 mg Tablet works by increasing the amount of urine passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney or lung disease. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, it also helps lower high blood pressure, reducing the chances of any future heart attack, stroke or angina (chest pain).

Storage

• Store in a cool and dry place away from sunlight.
• Keep out of sight and reach of children.
• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Planep T 20 mg Tablet

Do not take more than the prescribed dose. Taking more medication will not improve your symptoms; instead, it may cause poisoning or serious side effects. If you think there has been an overdose, call your doctor or get medical care right away.

Drug Warnings

Planep T 20 mg Tablet should not be given to the people allergic to Planep T 20 mg Tablet , have low blood pressure (less than 90 mm of Hg), have had a heart attack, kidney disease (with creatinine clearance less than 30 mL/min), liver disease, pregnant women, or planning to get pregnant and breastfeeding women. Besides this, it is contraindicated in low blood pressure (hypotension), cardiogenic shock (sudden stopping of blood flow to the heart), and aortic stenosis (heart valve problem). Planep T 20 mg Tablet can pass into breast milk, but its effect on the baby is unknown, so it is better to tell your doctor if you take Planep T 20 mg Tablet and breastfeeding. Dehydration with electrolyte and acid-base disturbances must be corrected before using Planep T 20 mg Tablet . Do not take extra potassium supplements or potassium-rich foods such as bananas and broccoli with Planep T 20 mg Tablet . It may lead to an excessive blood potassium level (hyperkalemia). Please take Planep T 20 mg Tablet at least 4 hours before sleeping to avoid frequent urination at night.

Drug-Drug Interactions

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EplerenonePotassium iodide
Critical
EplerenoneSaquinavir
Critical

Drug-Drug Interactions

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EplerenonePotassium iodide
Critical
How does the drug interact with Planep T 20 mg Tablet:
Combining Planep T 20 mg Tablet with Potassium iodide may significantly increase potassium levels in the blood which can lead to kidney issues, muscle paralysis (loss of muscle function) and irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Potassium iodide and Planep T 20 mg Tablet, you can take these medicines if prescribed by a doctor. Consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. Do not discontinue any medications without a doctor's advice.
EplerenoneSaquinavir
Critical
How does the drug interact with Planep T 20 mg Tablet:
Co-administration of EPELENONE and SAQUINAVIR may significantly increase the blood levels and side effects of Planep T 20 mg Tablet. This can increase the risk of serious side effects like high blood potassium, which in severe cases can lead to kidney failure, muscle paralysis (loss of muscle function) and irregular heart rhythm.

How to manage the interaction:
Taking saquinavir and Planep T 20 mg Tablet together is not recommended as it can lead to interaction. However, it can be taken if a doctor advises it. If you experience any unusual symptoms like headaches, irritation, confusion, edema (swelling caused by too much fluid accumulation), weakness, palpitations, or constipation, consult a doctor immediately. Do not stop using any medications without the doctor's advice.
How does the drug interact with Planep T 20 mg Tablet:
Combining Planep T 20 mg Tablet with Spiranolactone may significantly increase potassium levels in the blood which can lead to kidney issues and irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between spironolactone and Planep T 20 mg Tablet, it is not recommended as it can lead to an interaction. You can take these medicines if prescribed by a doctor. Consult a doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or an irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Planep T 20 mg Tablet:
Coadministration of posaconazole with Planep T 20 mg Tablet can increase the blood levels of Planep T 20 mg Tablet. This can increase the risk of serious side effects, including hyperkalemia (high blood potassium).

How to manage the interaction:
Although there is an interaction between posaconazole and Planep T 20 mg Tablet, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Planep T 20 mg Tablet:
Co-administration of Planep T 20 mg Tablet and Ritonavir may significantly increase the blood levels of Planep T 20 mg Tablet.

How to manage the interaction:
Taking Ritonavir and Planep T 20 mg Tablet together is not recommended as it can lead to an interaction. However, it can be taken if a doctor advises it. If you experience any unusual symptoms like headaches, irritation, confusion, edema (swelling caused by too much fluid accumulation), weakness, palpitations, or constipation, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Planep T 20 mg Tablet:
Coadministration of Ketoconazole with Planep T 20 mg Tablet can increase the levels of blood potassium which can lead to kidney damage and irregular heart rate.

How to manage the interaction:
Taking ketoconazole with Planep T 20 mg Tablet is not recommended as it can result in an interaction, but it can be taken if a doctor has advised it. However, if you notice any symptoms of headaches, irritation, confusion, edema (swelling caused by too much fluid accumulation), weakness, palpitations, or constipation, you should contact a doctor immediately. Do not stop using any medications without the doctor's advice.
EplerenoneNefazodone
Critical
How does the drug interact with Planep T 20 mg Tablet:
Coadministration of Nefazodone with Planep T 20 mg Tablet can increase the levels of Planep T 20 mg Tablet in the body.

How to manage the interaction:
Taking Nefazodone with Planep T 20 mg Tablet together is not recommended as it can result in an interaction, but it can be taken if your doctor has advised it. However, if you notice any symptoms of headaches, irritation, confusion, edema (swelling caused by too much fluid accumulation), weakness, palpitations, or constipation, you should contact a doctor immediately. Do not stop using any medications without a doctor's advice.
EplerenonePotassium citrate
Critical
How does the drug interact with Planep T 20 mg Tablet:
Taking Planep T 20 mg Tablet with Potassium citrate may significantly increase potassium levels in the blood which can lead to kidney issues, muscle paralysis (loss of muscle function) and irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Potassium citrate and Planep T 20 mg Tablet, you can take these medicines if prescribed by a doctor. Consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Planep T 20 mg Tablet:
The blood levels and effects of Planep T 20 mg Tablet may be greatly increased when combined with itraconazole.

How to manage the interaction:
Although there is a possible interaction between Planep T 20 mg Tablet and Itraconazole, it is not recommended; they can be taken if prescribed by a doctor. Consult a doctor if you have complications such as hyperkalemia (high blood potassium), which in extreme circumstances can result in kidney problems, muscle paralysis, and an irregular heartbeat. Without first consulting your doctor, never stop taking medicines.
How does the drug interact with Planep T 20 mg Tablet:
Co-administration of Planep T 20 mg Tablet and Clarithromycin may significantly increase the blood levels and effects of Planep T 20 mg Tablet.This may increase the risk or severity of side effects like high blood potassium which can lead to kidney damage and irregular heart rate.

How to manage the interaction:
Taking Clarithromycin with Planep T 20 mg Tablet is not recommended as it can lead to interaction. However, it can be taken if a doctor advises it. If you experience any unusual symptoms like headaches, irritation, confusion, edema (swelling caused by too much fluid accumulation), weakness, palpitations, or constipation, consult a doctor immediately. Do not stop using any medications without the Doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Keep your weight under control with a BMI of 19.5-24.9.
  • Regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week, can help lower your raised blood pressure by about 5 mm of Hg.
  • Opt for a diet rich in whole grains, fruits, veggies and low-fat dairy products.
  • Limit your daily sodium chloride (table salt) intake to 2300 mg per day, or less than 1500 mg, which is ideal for most adults.
  • If you take alcohol, only one serving for women and two servings for men is advisable.
  • Quitting smoking is the best strategy to lower the risk of heart disease.
  • Avoid chronic stress, as it can raise your blood pressure. To cope with stress, try to enjoy and spend time with your loved ones and practice mindfulness techniques.
  • Monitor your blood pressure daily, and immediately contact your doctor if there is too much fluctuation.
  • Try to include heart-healthy omega-3 fatty acid-containing food and drinks in your daily diet. You can also use low-fat cooking oils like olive oil, soybean oil, canola oil, and coconut oil to lower your elevated blood pressure.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Planep T 20 mg Tablet Substitute

Substitutes safety advice
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Alcohol

Caution

Avoid consuming alcohol while on treatment with Planep T 20 mg Tablet as it may lead to serious side effects.

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Pregnancy

Caution

Planep T 20 mg Tablet is generally not recommended during pregnancy. Talk to your doctor about the benefits and potential risks of taking this medicine if you're trying to get pregnant or are already pregnant.

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Breast Feeding

Caution

Planep T 20 mg Tablet is generally not advised during breastfeeding. Planep T 20 mg Tablet should be used in breastfeeding mothers only if the benefits outweigh the risks.

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Driving

Caution

It is not advised to drive after taking Planep T 20 mg Tablet because it may cause drowsiness due to orthostatic hypotension (sudden drop in blood pressure on standing from a lying position).

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Liver

Caution

Planep T 20 mg Tablet to be taken with caution, especially if you have a history of Liver diseases/conditions. Your doctor may adjust the dose depending on your current liver conditions.

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Kidney

Caution

Planep T 20 mg Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. Your doctor may adjust the dose depending on your current kidney conditions.

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Children

Unsafe

Planep T 20 mg Tablet is not recommended for children below 12 years of age.

Have a query?

FAQs

Planep T 20 mg Tablet is used to treat oedema (fluid overload) and hypertension (high blood pressure).

Planep T 20 mg Tablet works by increasing the amount of urine passed out from the kidneys. It effectively reduces excess fluid levels and treats Oedema (swelling) associated with heart, liver, kidney or lung disease. This reduces the heart&amp;#039;s workload and makes the heart more efficient at pumping blood throughout the body. Thus, it also helps lower high blood pressure, reducing the chances of any future heart attack, stroke or angina (chest pain).

The main side effect of Planep T 20 mg Tablet is peeing (urination) more often than usual. Most people need to pee about 30 minutes after taking Planep T 20 mg Tablet and again within a few hours. Do not take Planep T 20 mg Tablet before going to bed, or you may have to wake up in the night to go for urination frequently.

Yes, Planep T 20 mg Tablet is known to cause dehydration (excessive loss of fluids). The patient may experience dry mouth, decreased urine output, excessive thirst, and hypotension (decreased blood pressure). So, please increase the intake of fluids to avoid excessive dehydration.

Yes, Planep T 20 mg Tablet can cause increased potassium levels (hyperkalemia), especially in patients with kidney problems or if you are taking potassium supplements along with Planep T 20 mg Tablet . Please monitor your electrolyte level regularly to avoid increasing blood potassium levels.

Yes, Planep T 20 mg Tablet may occasionally cause dizziness due to orthostatic hypotension (sudden drop in blood pressure when standing from a lying position) or passing out. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.

The side effects of Planep T 20 mg Tablet include electrolyte disturbances (calcium, magnesium, and sodium), constipation, dehydration, itching, and increased uric acid. Most of these side effects do not require medical attention and gradually resolve over time. However, consult the doctor if these side effects persist or worsen.

Planep T 20 mg Tablet may increase creatinine levels as they affect kidney function. Therefore, consult a doctor before taking this medication; it’s important to monitor kidney function regularly while using these medications.

When taking Planep T 20 mg Tablet , it's essential to follow certain precautions. If you have kidney problems, your doctor may need to adjust your dose. Additionally, monitor your potassium levels, as Planep T 20 mg Tablet can increase potassium levels in the blood. Inform your doctor about your medications, supplements, and vitamins to avoid potential interactions. Consult your doctor before taking Planep T 20 mg Tablet if you are pregnant, breastfeeding, or planning to become pregnant. Be sure to follow your doctor's instructions for dosage and attend all scheduled follow-up appointments. Immediately report any signs of hyperkalemia (high potassium levels) or other adverse reactions to your doctor. Your doctor may periodically check your kidney function, blood pressure, and potassium levels while taking Planep T 20 mg Tablet .

Planep T 20 mg Tablet should not be used during pregnancy unless absolutely necessary. Therefore, consult a doctor if you are pregnant. Before prescribing this medication, your doctor will carefully assess the benefits and potential risks.

Planep T 20 mg Tablet may cause constipation as a common side effect. If you experience this symptom, drink plenty of water to stay hydrated, eat a fibre-rich diet, exercise regularly, and limit caffeine intake.

Planep T 20 mg Tablet should be used with caution in patients with kidney problems. If you have a history of kidney disease, consult your doctor before taking Planep T 20 mg Tablet . Your doctor may need to adjust your dose depending on your current kidney condition.

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India Country of Origin: India
Other Info - PLA0246

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