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  3. Polynase 5Ml Eye Drops

Polynase 5Ml Eye Drops, Pack of 1
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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Polynase 5Ml Eye Drops is used to treat bacterial infections of the eye (optic). It contains Polymyxin B and Chloramphenicol, which work by killing the bacteria and preventing the spread of eye infections caused by a wide range of gram-negative bacteria. In some cases, you may experience side effects such as redness, itching, irritation, burning or stinging sensations in the eyes, blurred vision, sensitivity to light, eyelid swelling, itching, or crusting. Before using this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant or breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

CHLORAMPHENICOL-4MG + POLYMYXIN B-5000IU

Manufacturer/Marketer :

Ajanta Pharma Ltd

Consume Type :

OPHTHALMIC

Return Policy :

Not Returnable

Expires on or after :

About Polynase 5Ml Eye Drops

Polynase 5Ml Eye Drops belongs to a combination of medicines called 'antibiotics,' primarily used to treat bacterial infections of the eye. Bacterial eye infection occurs when harmful bacteria enter any part of the eyeball or surrounding tissues, including the cornea (front surface of the eye) and the lining of the outer eye and inner eyelids (conjunctiva).

Polynase 5Ml Eye Drops is a combination of two antibiotics, namely: Polymyxin B and Chloramphenicol. Polymyxin B is bactericidal, killing bacteria by preventing the formation of bacterial cell walls, which are essential for their survival. Chloramphenicol is bacteriostatic, which prevents bacterial growth by inhibiting the production of essential proteins necessary for bacterial growth and multiplication. Polynase 5Ml Eye Drops prevents the spread of eye infections caused by a wide range of gram-negative bacteria.

Use Polynase 5Ml Eye Drops as prescribed by your doctor. This medicine is intended for use in the eyes only. Do not swallow or inject Polynase 5Ml Eye Drops. You are advised to use this medicine for as long as your doctor has prescribed it based on your medical condition. In some cases, you may experience redness, itching, irritation, burning/stinging sensations in the eyes, blurred vision, sensitivity to light, eyelid swelling, itching, or crusting as side effects. Most of these side effects of Polynase 5Ml Eye Drops do not require medical attention and typically resolve on their own over time. However, if any of these side effects worsen or persist, please consult your doctor.

If you are allergic to Polynase 5Ml Eye Drops or any other medicines, please inform your doctor. Polynase 5Ml Eye Drops should be used with caution in children. Consult your doctor if you are pregnant or breastfeeding before using Polynase 5Ml Eye Drops. You are recommended not to use contact lenses during the course of Polynase 5Ml Eye Drops as it may worsen the infection. If you experience any new eye problems, an eye infection, or notice any allergic reactions such as itching, redness of the eye, or a skin rash, please consult your doctor immediately. You are advised to maintain a 10-minute time gap between using Polynase 5Ml Eye Drops and other eye drops. Please do not contact the container tip to the eye, eyelids, or surrounding areas, as it may contaminate Polynase 5Ml Eye Drops and cause eye infections.

Uses of Polynase 5Ml Eye Drops

Polynase 5Ml Eye Drops is used in the treatment of bacterial eye infections. The detailed uses of Polynase 5Ml Eye Drops are as follows:<br/>•Bacterial Conjunctivitis: Polynase 5Ml Eye Drops is commonly used to treat conjunctivitis (pink eye) caused by bacterial infections.<br/>•Bacterial Keratitis: Polynase 5Ml Eye Drops is also used to treat bacterial infections of the cornea and helps prevent potential vision loss due to corneal damage.<br/>•Post-Surgical Inflammation: Polynase 5Ml Eye Drops may be used to prevent infection after certain eye surgeries.<br/>

Directions for Use

  • Polynase 5Ml Eye Drops is for ophthalmic (for eye) use only.
  • It is recommended to instil 1-2 drops of Polynase 5Ml Eye Drops, 2-3 times daily, or as advised by your doctor.
  • Lie down and tilt your head backwards. Gently pull your lower eyelid with your index finger to form a pocket. Place the prescribed amount of Polynase 5Ml Eye Drops into the pocket. Close your eyes for 1-2 minutes. 
  • Replace the outer cap tightly after use.
  • Avoid touching the container tip to your eye, eyelids, or surrounding areas to prevent contamination.

Medicinal Benefits

Polynase 5Ml Eye Drops is a combination of two antibiotics: Polymyxin B and Chloramphenicol. It is used to treat bacterial infections of the eye, like conjunctivitis. Polymyxin B is bactericidal (kills bacteria) in nature, inhibiting bacterial cell wall formation required for their survival. Thus, it prevents the entry of unwanted substances into the cells and stops the leakage of cell contents. Chloramphenicol is bacteriostatic (prevents bacterial growth) in nature, with excellent eye penetration, and exhibits broad-spectrum coverage against various bacteria that cause eye infections by inhibiting the protein synthesis process required for bacterial survival.

How Polynase 5Ml Eye Drops Works

Polynase 5Ml Eye Drops is a combination of two antibiotics, namely: Polymyxin B and Chloramphenicol. Polymyxin B is bactericidal, killing bacteria by preventing the formation of bacterial cell walls, which are essential for their survival. Chloramphenicol is bacteriostatic, which prevents bacterial growth by inhibiting the production of essential proteins necessary for bacterial growth and multiplication.

Storage

Keep Polynase 5Ml Eye Drops out of reach and sight of children.

What if I have taken an overdose of Polynase 5Ml Eye Drops

Do not use Polynase 5Ml Eye Drops in more doses or more often than prescribed, as it may lead to an overdose. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

If you are allergic to Polynase 5Ml Eye Drops or any other medicines, please tell your doctor. Polynase 5Ml Eye Drops should be used with caution in children. You are advised to consult a doctor if you are pregnant or breastfeeding before using this medicine. You are recommended not to use contact lenses during the course of Polynase 5Ml Eye Drops as it may worsen the infection. If you get any new eye problem, an eye infection, or notice any allergic reactions such as itching or redness of the eye and a skin rash, please consult your doctor immediately. You are advised to maintain 10 10-minute time gap between using Polynase 5Ml Eye Drops and other eye drops. Please do not touch the container tip to the eye, eyelids, or surrounding areas, as it may contaminate Polynase 5Ml Eye Drops and cause eye infections.

Diet & Lifestyle Advise

  • Wash your hands with soap and water frequently.
  • Keep your clothes, towels, and bedsheets separate from others.
  • Maintain good hygiene of contact lenses. Wash your hands thoroughly before putting in and after taking out contact lenses.
  • Avoid wearing contact lenses while swimming. If you misuse them, get a new pair.
  • Wear protective eyegear if you are cycling or trekking through the forest.
  • If you experience eye irritation, avoid rubbing your eyes.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

Polynase 5Ml Eye Drops Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

Interaction of alcohol with Polynase 5Ml Eye Drops is unknown. However, consult your doctor in case of any concerns.

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Pregnancy

Caution

If you are pregnant, consult your doctor before using Polynase 5Ml Eye Drops. Your doctor may prescribe Polynase 5Ml Eye Drops if the benefits outweigh the risks.

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Breast Feeding

Caution

Please consult your doctor if you are a breastfeeding mother, as it is not known if Polynase 5Ml Eye Drops is excreted in human milk.

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Driving

Caution

Polynase 5Ml Eye Drops may cause blurred vision immediately after using it. So, wait until your vision is clear before driving or operating machinery.

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Liver

Caution

If you have any concerns regarding the use of Polynase 5Ml Eye Drops in patients with liver problems, please consult a doctor.

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Kidney

Caution

If you have any concerns regarding the use of Polynase 5Ml Eye Drops in patients with kidney problems, please consult a doctor.

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Children

Caution

Polynase 5Ml Eye Drops should be used in children only if prescribed by a doctor.

Have a query?

FAQs

Polynase 5Ml Eye Drops is used to treat bacterial infections of the eye (optic).

Polynase 5Ml Eye Drops contains Polymyxin B and Chloramphenicol. Polymyxin B works by inhibiting the formation of bacterial cell walls, which are necessary for survival because they prevent unwanted substances from entering the cells and stop the leakage of cell contents. Chloramphenicol inhibits the production of essential proteins required for bacterial growth and multiplication. Bacteria are thus destroyed. They work together to relieve itching, pain, and discomfort in the eye caused by infection.

You are not recommended to use chymotrypsin while using Polynase 5Ml Eye Drops as it may reduce the effectiveness of chymotrypsin (used during cataract surgery). However, please consult your doctor before using other medicines with Polynase 5Ml Eye Drops.

You are not recommended to wear contact lenses during the entire course of Polynase 5Ml Eye Drops as it may worsen the infection. Therefore, you are advised to remove contact lenses before using Polynase 5Ml Eye Drops and reinsert them after 24 hours of finishing the course of Polynase 5Ml Eye Drops.

You are recommended to maintain a minimum of 10 minutes time gap between using Polynase 5Ml Eye Drops and other eye drops, and administer eye ointments last.

Yes, Polynase 5Ml Eye Drops may cause temporary blurred vision. Therefore, wait until your vision is clear before driving or operating heavy machinery.

You are not recommended to stop using Polynase 5Ml Eye Drops without consulting your doctor, as it may increase eye pressure and lead to loss of vision. Therefore, use Polynase 5Ml Eye Drops for as long as your doctor has prescribed it. If you experience any difficulty while using Polynase 5Ml Eye Drops, please consult your doctor.

Polynase 5Ml Eye Drops may affect glaucoma if used for a longer duration. Therefore, use Polynase 5Ml Eye Drops only for the duration advised by the doctor. If you have glaucoma, tell your doctor before using Polynase 5Ml Eye Drops. They will monitor your eye pressure and adjust your treatment plan as needed.

Polynase 5Ml Eye Drops is not recommended for eye ulcers. It is used to treat bacterial infections of the eye.

Polynase 5Ml Eye Drops potentially doesn’t cause blindness when used as suggested by your doctor. However, it may cause temporary blurred vision. Therefore, it is recommended that you wait until your vision is clear before driving or operating heavy machinery.

Yes, Polynase 5Ml Eye Drops is an antibiotic. It works by inhibiting the production of essential proteins that bacteria require for growth and multiplication. Thus, it helps treat bacterial eye infections.

Polynase 5Ml Eye Drops should be stored in a cool and dry place away from sunlight. Dispose of expired or unused medicine promptly. Consult your pharmacist for proper disposal methods.

Gently clean the extra medication with the towel and rinse your eyes thoroughly with water. If you experience any issues, contact your doctor immediately.

Common side effects of Polynase 5Ml Eye Drops may include redness, itching, irritation, a burning or stinging sensation in the eyes, blurred vision, sensitivity to light, eyelid swelling, itching, or crusting. Most of these side effects of Polynase 5Ml Eye Drops do not require medical attention and typically resolve on their own over time. However, if any of these side effects worsen or persist, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Ajanta House, Charkop, Kandivli West, Mumbai 400 067, India
Other Info - POL0362

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:43 AM IST

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Reference

  1. https://www.drugs.com/mtm/chloramphenicol-ophthalmic.html
  2. https://www.drugs.com/mtm/polymyxin-b-ophthalmic.html
  3. https://www.medicines.org.uk/emc/files/pil.3740.pdf
  4. https://www.centaurpharma.com/downloads/2022/ophthalmology/anti-infectives/Ocupol%20Eye%20drops%20Ointment.pdf
  5. https://www.swissvision.in/product/polmichem-c-eye-drop/

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