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  3. Pradaxa 110 mg Capsule 10's

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Pradaxa 110 mg Capsule 10's, Pack of 10 CAPSULES
Pradaxa 110 mg Capsule 10's, Pack of 10 CAPSULES
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Composition :

DABIGATRAN ETEXILATE-110MG

Manufacturer/Marketer :

Boehringer Ingelheim India Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Pradaxa 110 mg Capsule

Pradaxa 110 mg Capsule is used to prevent and treat the risk of stroke, heart attack in patients with atrial fibrillation (irregular heart rhythm) by reducing blood clot formation. It is also used to prevent deep vein thrombosis (blood clots in leg veins) and pulmonary embolism (blood clots in the lung).

Pradaxa 110 mg Capsule contains Dabigatran etexilate that works by inhibiting the production of clotting factor Xa, also called thrombin. This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots.

You may experience bleeding, anaemia (low number of red blood cells), nausea, stomach pain, and vomiting. Most of these side effects do not require medical attention. However, talk to your doctor if you experience these side effects persistently.

If you are known to be allergic to Pradaxa 110 mg Capsule or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Pradaxa 110 mg Capsule . If you have a stomach ulcer, kidney or liver problems, high blood pressure, or bleeding problems, inform your doctor before taking Pradaxa 110 mg Capsule .

Uses of Pradaxa 110 mg Capsule

Pradaxa 110 mg Capsule is used in the prevention of blood clot formation, deep vein thrombosis, and pulmonary embolism. The detailed uses of Pradaxa 110 mg Capsule are as follows:

  • Stroke Prevention: Pradaxa 110 mg Capsule is used especially in patients with non-valvular atrial fibrillation.
  • Deep Vein Thrombosis (DVT): Pradaxa 110 mg Capsule treats and prevents clots in the legs.
  • Pulmonary Embolism (PE): Pradaxa 110 mg Capsule prevents clots from traveling to the lungs.
  • Post-Surgical Clot Prevention: Pradaxa 110 mg Capsule is used in clot prevention after hip or knee replacement surgery.
  • Recurrent Clot Prevention: Pradaxa 110 mg Capsule reduces risk of DVT/PE recurrence.

Have a query?

Directions for Use

  • Pradaxa 110 mg Capsule can be taken with or without food.
  • It is usually taken twice daily, or as prescribed by your doctor.
  • Swallow the whole Pradaxa 110 mg Capsule with a glass of water.
  • Do not break, chew, or open it.

Medicinal Benefits

  • Pradaxa 110 mg Capsule is primarily used to prevent and treat the risk of stroke and heart attack by reducing blood clot formation.
  • It makes the blood flow easily through the veins, making it less likely to form a serious blood clot. Thus, Pradaxa 110 mg Capsule helps prevent blood clots, thereby reducing the risk of heart attack/stroke.
  • It also reduces the risk of getting clots in people who have undergone knee or hip replacement surgeries. Pradaxa 110 mg Capsule works by stopping the action of the clotting factor (thrombin).
  • Pradaxa 110 mg Capsule prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots.
  • Reduces the risk of stroke in persons with atrial fibrillation (irregular heartbeat).

How Pradaxa 110 mg Capsule Works

Pradaxa 110 mg Capsule contains Dabigatran etexilate that works by inhibiting the production of clotting factor Xa, also called thrombin. This prevents the conversion of fibrinogen (a soluble protein) to fibrin (an insoluble protein), thereby preventing blood clots. It facilitates the smooth flow of blood through the veins, reducing the likelihood of forming a serious blood clot. Thus, Pradaxa 110 mg Capsule helps prevent blood clots, thereby reducing the risk of heart attacks and strokes.

Storage

• Store in a cool and dry place away from sunlight. • Keep Pradaxa 110 mg Capsule out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Pradaxa 110 mg Capsule
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Avoid other medicines that increase the risk of bleeding.
  • Use an electric razor and a soft-bristled toothbrush.
  • Monitor for signs of bleeding like bleeding gums, unusual bruising, blood in stool, nosebleeds, or heavy menstrual bleeding.
  • If you experience severe bleeding, apply direct pressure on the wound and consult a doctor promptly.
  • If the risk of bleeding is high, discuss with your doctor about possibility of switching to different medicine with a lower bleeding risk.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

What if I have taken an overdose of Pradaxa 110 mg Capsule

Please do not exceed the recommended dose, as it might cause serious side effects. Signs and symptoms of an overdose of Pradaxa 110 mg Capsule may include an increased risk of bleeding. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

  • If you are known to be allergic to Pradaxa 110 mg Capsule or any other medicines, please tell your doctor.
  • Do not stop taking this medicine on your own. Discontinuing Pradaxa 110 mg Capsule may worsen your condition and increase the risk of heart attack and stroke.
  • Pradaxa 110 mg Capsule is not recommended for children less than 18 years of age, as the Safety and effectiveness have not been established.
  • If you have an artificial heart valve, stomach ulcer, kidney/liver problems, high blood pressure, or bleeding problems, inform your doctor before taking Pradaxa 110 mg Capsule .
  • Avoid consumption of alcohol while taking Pradaxa 110 mg Capsule as it may increase the risk of stomach bleeding.
  • If you are pregnant or breastfeeding, it is advised to consult a doctor before using Pradaxa 110 mg Capsule .
  • You should inform the doctor that you are taking Pradaxa 110 mg Capsule if you are due to undergo surgery.

Drug-Drug Interactions

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Dabigatran etexilateMifepristone
Critical
Dabigatran etexilatePrasugrel
Severe

Drug-Drug Interactions

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Dabigatran etexilateMifepristone
Critical
How does the drug interact with Pradaxa 110 mg Capsule:
When Mifepristone is taken with Pradaxa 110 mg Capsule, it may increase the risk of severe vaginal bleeding in women.

How to manage the interaction:
Taking Mifepristone with Pradaxa 110 mg Capsule is not recommended, but it can be taken if prescribed by the doctor. However, if you experience heavy, persistent vaginal bleeding, consult the door. Do not stop using any medications without talking to a doctor.
Dabigatran etexilatePrasugrel
Severe
How does the drug interact with Pradaxa 110 mg Capsule:
Taking Pradaxa 110 mg Capsule with Prasugrel can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Although taking Prasugrel and Pradaxa 110 mg Capsule together can evidently cause an interaction, it can be taken if a doctor has suggested it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
Dabigatran etexilateRifampicin
Severe
How does the drug interact with Pradaxa 110 mg Capsule:
Taking Pradaxa 110 mg Capsule with rifampicin can decrease the blood levels of Pradaxa 110 mg Capsule, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between Pradaxa 110 mg Capsule and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
Dabigatran etexilateSulindac
Severe
How does the drug interact with Pradaxa 110 mg Capsule:
Combining Sulindac with Pradaxa 110 mg Capsule can increase the risk of bleeding and hemorrhage.

How to manage the interaction:
Taking Pradaxa 110 mg Capsule with Sulindac together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
Dabigatran etexilatePrimidone
Severe
How does the drug interact with Pradaxa 110 mg Capsule:
Taking Pradaxa 110 mg Capsule with Primidone can increase the risk of bleeding.

How to manage the interaction:
Taking Pradaxa 110 mg Capsule with Primidone together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Dabigatran etexilatePiroxicam
Severe
How does the drug interact with Pradaxa 110 mg Capsule:
Coadministration of Piroxicam with Pradaxa 110 mg Capsule can increase the risk of bleeding.

How to manage the interaction:
There may be a possibility of interaction between Piroxicam and Pradaxa 110 mg Capsule, but it can be taken if prescribed by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without talking to a doctor.
Dabigatran etexilatePhenytoin
Severe
How does the drug interact with Pradaxa 110 mg Capsule:
Coadministration of Phenytoin and Pradaxa 110 mg Capsule may decrease the blood levels of Pradaxa 110 mg Capsule, which may make Pradaxa 110 mg Capsule less effective.

How to manage the interaction:
Although taking Phenytoin and Pradaxa 110 mg Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. Without consulting a doctor, never stop taking any drugs.
Dabigatran etexilateUrokinase
Severe
How does the drug interact with Pradaxa 110 mg Capsule:
Taking Pradaxa 110 mg Capsule with Urokinase can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Pradaxa 110 mg Capsule with Urokinase together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
Dabigatran etexilateFosphenytoin
Severe
How does the drug interact with Pradaxa 110 mg Capsule:
When Pradaxa 110 mg Capsule is taken with Fosphenytoin, it can lower the rate at which the body breaks down Pradaxa 110 mg Capsule. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Fosphenytoin with Pradaxa 110 mg Capsule together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're having symptoms like sudden breathlessness, sharp chest pain, throbbing, cramping pain, swelling, redness or warmth in legs or arms, it's important to let your doctor know right away. They can recommend other options that won't cause any problems with your current medications. Do not discontinue any medications without first consulting your doctor.
Dabigatran etexilateVerapamil
Severe
How does the drug interact with Pradaxa 110 mg Capsule:
Taking Verapamil with Pradaxa 110 mg Capsule may increase the blood levels and effects of dabigatran. This can increase the risk or severity of side effects.

How to manage the interaction:
Although taking Pradaxa 110 mg Capsule and Verapamil together may result in an interaction, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience paleness of skin, fatigue, dizziness, fainting, unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, or weakness. Do not discontinue any medication without consulting a doctor.

Drug-Food Interactions

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DABIGATRAN ETEXILATE-110MGHerbal products/medicines

Drug-Food Interactions

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DABIGATRAN ETEXILATE-110MGHerbal products/medicines
Common Foods to Avoid:
St. John’S Wort, Garlic Pill

How to manage the interaction:
Herbs and supplements may interact with Pradaxa 110 mg Capsule. Avoid St. John's Wort, herbs including garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba during Pradaxa 110 mg Capsule treatment.

Diet & Lifestyle Advise

  • Maintain healthy cholesterol and triglyceride levels.
  • Eat at regular intervals, and maintain a healthy diet that includes fresh fruits and vegetables.
  • Limit alcohol intake since it raises blood pressure and increases the risk of heart disease.
  • Monitor your weight and exercise regularly to maintain a healthy heart.

Habit Forming

No

Therapeutic Class

ANTICOAGULANT/ANTITHROMBOTIC

Pradaxa 110 mg Capsule Substitute

Substitutes safety advice
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Alcohol

Unsafe

You are recommended to avoid consumption of alcohol with Pradaxa 110 mg Capsule as it may increase the risk of bleeding.

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Pregnancy

Consult your doctor

Please consult your doctor if you are planning to become pregnant or are already pregnant before starting Pradaxa 110 mg Capsule . Your doctor will prescribe Pradaxa 110 mg Capsule only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Pradaxa 110 mg Capsule . Consult your doctor if you have any concerns.

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Driving

Consult your doctor

Pradaxa 110 mg Capsule usually does not affect your ability to drive or operate machinery. Consult your doctor if you have any concerns.

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Liver

Caution

Let your doctor know if you have/had liver diseases or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Pradaxa 110 mg Capsule . However, it is not recommended for patients with severe liver diseases.

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Kidney

Caution

Let your doctor know if you have/had kidney diseases. Your doctor will weigh the benefits and potential risks before prescribing Pradaxa 110 mg Capsule . However, it is not recommended for patients with severe kidney diseases.

bannner image

Children

Unsafe

Pradaxa 110 mg Capsule is not recommended for children below the age of 18 years, as the safety and efficacy of Pradaxa 110 mg Capsule have not been established in children.

FAQs

Pradaxa 110 mg Capsule is used to prevent blood clot formation, deep vein thrombosis (blood clots in deep veins), and pulmonary embolism (blood clots in the lungs).

Pradaxa 110 mg Capsule is a thrombin inhibitor. The inhibition of thrombin reduces the formation of blood-clotting material fibrin, thereby leading to fewer clots and aiding the free flow of blood.

Please consult your doctor if you are due to undergo surgery. The doctor might ask you to stop taking Pradaxa 110 mg Capsule a few days before surgery since it can cause an increased risk of bleeding during surgery.

Taking Pradaxa 110 mg Capsule during pregnancy may cause bleeding in the mother or the newborn baby. However, please consult your doctor if you are planning to become pregnant or already pregnant before starting Pradaxa 110 mg Capsule .

Pradaxa 110 mg Capsule may increase the risk of bleeding. It is advised to be cautious during your daily activities like shaving, cutting fingernails, or using sharp objects. Inform your doctor immediately if you notice any abnormal staining or bleeding.

No, you are not recommended to stop taking Pradaxa 110 mg Capsule without consulting your doctor as it may worsen the condition. Therefore, take Pradaxa 110 mg Capsule for as long as your doctor has prescribed it.

Because of the risk of bleeding, your dose of dabigatran may need to be lowered or stopped a few days before you have an operation.

You can take Pradaxa 110 mg Capsule with or without food but try to take it at the same time every day. Swallow the capsules whole with a drink of water. Do not open dabigatran capsules before taking them, as this increases the risk of side effects.

Take Pradaxa 110 mg Capsule as prescribed by your doctor. Depending on your medical conditions, you are advised to take Pradaxa 110 mg Capsule as long as your doctor has prescribed it for you.

You are recommended to avoid consumption of alcohol with Pradaxa 110 mg Capsule as it may increase the risk of bleeding.

Hair loss is not a known side effect of Pradaxa 110 mg Capsule . However, it is known to occur with anticoagulants. Consult your doctor if you observe hair loss. Your doctor will guide you on how to cope with this situation.

It varies from person to person and depends on the conditions that we treat.

Limited research available. Let your doctor know if you have/had liver diseases or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Pradaxa 110 mg Capsule . However, it is not recommended in patients with severe liver diseases.

Store in a cool and dry place away from sunlight. Keep Pradaxa 110 mg Capsule out of the sight and reach of children.

Yes, bleeding is the main risk associated with Pradaxa 110 mg Capsule treatment; patients should be monitored for signs of bleeding.

Pradaxa 110 mg Capsule is not suitable for some people with existing medical conditions. So, to ensure safety, let your doctor know about all your medical conditions and medications. Your doctor will weigh the benefits and potential risks before prescribing Pradaxa 110 mg Capsule .

Common side effects of Pradaxa 110 mg Capsule may include bleeding, anaemia, nausea, stomach pain, and vomiting.

Country of origin

Germany

Manufacturer/Marketer address

1102, Hallmark Business Plaza, 11th Floor, Gurunanak Hospital Road, Near Gurunanak Hospital, Bandra (East), Mumbai 400051
Other Info - PRA0179

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Sep 29, 2025 | 9:28 AM IST

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Reference

  1. https://www.drugs.com/mtm/dabigatran.html
  2. https://www.nhs.uk/medicines/dabigatran/
  3. https://www.medicines.org.uk/emc/files/pil.6229.pdf
  4. https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/022512s007lbl.pdf

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