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Manufacturer/Marketer :

Torrent Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Pregaba Plus Capsule

Pregaba Plus Capsule belongs to the class of medications ‘anticonvulsants’ used in the treatment of neuropathic pain. Neuropathic pain is a chronic (long-term) progressive nerve disease that causes nerve pain due to nerve damage or the nervous system's malfunctioning. It is mostly seen in patients who had suffered a trauma or nerve injury, diabetes, vitamin deficiencies, cancer, multiple sclerosis (disease of the brain and spinal cord), shingles (a viral infection), and HIV.

Pregaba Plus Capsule is a combination of two medicines: Pregabalin and Methylcobalamin. Pregabalin acts by decreasing the pain signals sent by a damaged nerve in the body. On the other hand, Methylcobalamin helps rejuvenate and protect damaged nerve cells by producing a substance called myelin (outer protective layer of nerve cell - neuron).

You should take this medicine as prescribed by your doctor. The common side-effects of Pregaba Plus Capsule are dizziness, drowsiness, headache, anorexia (loss of appetite), nausea or vomiting, diarrhea, headache, hot sensation (burning pain), vision problems, and diaphoresis (sweating). Inform your doctor if any of these side effects persist.

Do not take Pregaba Plus Capsule if you are allergic to ‘Pregabalin’ and ‘Methylcobalamin’ or any contents before taking Pregaba Plus Capsule if you have a history of heart diseases, liver or kidney disease, alcoholism, or drug abuse.  It should not be used in children and adolescents below 18 years. Inform your doctor if you are pregnant and breastfeeding. Do not drive or operate heavy machinery as Pregaba Plus Capsule may cause dizziness or drowsiness. Pregaba Plus Capsule contains lactose, so inform your doctor if you have any intolerance to sugars. Do not discontinue treatment without telling your doctor. 

Uses of Pregaba Plus Capsule

Pregaba Plus Capsule is used in the treatment of Neuropathic pain. The detailed uses of Pregaba Plus Capsule are as follows:<br/>•Anxiety Relief: Pregaba Plus Capsule known is to help reduce anxiety and tension, fostering a sense of calm and relaxation.<br/>•Pain Management: Pregaba Plus Capsule may provide effective relief from various types of pain, including headaches and muscle discomfort.<br/>•Sleep Aid: Pregaba Plus Capsule can be beneficial for individuals experiencing sleep disturbances, helping to enhance sleep quality and duration.<br/>•Mood Stabilization: Pregaba Plus Capsule may assist in managing mood swings and supporting individuals with depressive symptoms, promoting emotional balance.<br/>•Neuropathic Pain Relief: Pregaba Plus Capsule helps reduce nerve pain by calming overactive nerves and supports nerve repair and regeneration.<br/>

Directions for Use

• Take Pregaba Plus Capsule with or without food or as advised by a doctor.• Recommended to take the medicine twice a day, in the morning and evening or as advised by your doctor.• Swallow the medicine as a whole with glass of water.• Do not crush, break, or chew it.

Medicinal Benefits

Pregaba Plus Capsule is a combination of two drugs: Pregabalin and Methylcobalamin. Pregabalin is an anticonvulsant that affects the brain's chemicals that send pain signals across the nervous system. It works by binding to the specific site on voltage-gated calcium channels (responsible for excitatory response), thereby decreasing brain activity. This effect helps in relieving nerve pain and lowers the risk of seizures. On the other hand, Methylcobalamin is a form of vitamin B12 that helps rejuvenate and protect damaged nerve cells by producing a substance called myelin (outer protective layer of nerve cells). Together, Pregaba Plus Capsule helps in providing relief from neuropathic pain and improved nerve signal conduction.  

 

How Pregaba Plus Capsule Works

Pregaba Plus Capsule is a combination of two medicines: Pregabalin and Methylcobalamin. Pregabalin acts by decreasing the pain signals sent by a damaged nerve in the body. On the other hand, Methylcobalamin helps rejuvenate and protect damaged nerve cells by producing a substance called myelin (outer protective layer of nerve cell - neuron).

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Pregaba Plus Capsule

Do not take more than the prescribed dose of Pregaba Plus Capsule as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Pregaba Plus Capsule may increase the risk of heart failure in patients with heart diseases. It may cause dizziness and somnolence (sleepiness). So, it might increase the risk of accidental injury in elderly patients. Pregaba Plus Capsule may also cause temporary vision problems. However, if this condition is persistent, consult your doctor immediately. Patients with diabetes who gain weight with Pregaba Plus Capsule may need a change in diabetic medicines. If you notice decreased urination while taking Pregaba Plus Capsule, inform your doctor as Pregaba Plus Capsule may cause kidney failure in some cases. It may increase suicidal tendencies, though it is rare. You may experience convulsions after discontinuing Pregaba Plus Capsule. In such cases, inform your doctor immediately.  

Drug-Drug Interactions

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PregabalinEsketamine
Severe
PregabalinHydrocodone
Severe

Drug-Drug Interactions

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PregabalinEsketamine
Severe
How does the drug interact with Pregaba Plus Capsule:
When Pregaba Plus Capsule and Esketamine are taken together, it may increase the risk of side effects.

How to manage the interaction:
Although taking Pregaba Plus Capsule and Esketamine together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience symptoms such as drowsiness, confusion, difficulty concentrating, and impairment in thinking, judgment, reaction speed, and motor coordination. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinHydrocodone
Severe
How does the drug interact with Pregaba Plus Capsule:
Using Pregaba Plus Capsule together with Hydrocodone causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Hydrocodone and Pregaba Plus Capsule together can result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinHydromorphone
Severe
How does the drug interact with Pregaba Plus Capsule:
Using Pregaba Plus Capsule together with Hydromorphone causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Hydromorphone and Pregaba Plus Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
How does the drug interact with Pregaba Plus Capsule:
Using Pregaba Plus Capsule together with Nalbuphine causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking Nalbuphine and Pregaba Plus Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinRemifentanil
Severe
How does the drug interact with Pregaba Plus Capsule:
Using Pregaba Plus Capsule together with Remifentanil causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking remifentanil and Pregaba Plus Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
How does the drug interact with Pregaba Plus Capsule:
Using Pregaba Plus Capsule together with Butorphanol causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Butorphanol and Pregaba Plus Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. If you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
How does the drug interact with Pregaba Plus Capsule:
Using Pregaba Plus Capsule together with Buprenorphine causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Buprenorphine and Pregaba Plus Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, and impairment in- judgment, reaction speed and motor coordination, consult the doctor immediately. Avoid driving or operating dangerous machinery. Do not exceed the doses, frequency, or duration of usage advised by the doctor. Do not discontinue any medications without consulting a doctor.
PregabalinCodeine
Severe
How does the drug interact with Pregaba Plus Capsule:
Using Pregaba Plus Capsule together with Codeine may cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Codeine and Pregaba Plus Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinPethidine
Severe
How does the drug interact with Pregaba Plus Capsule:
Using Pregaba Plus Capsule together with Pethidine causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking pethidine and Pregaba Plus Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinOxycodone
Severe
How does the drug interact with Pregaba Plus Capsule:
Using Pregaba Plus Capsule together with Oxycodone causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking oxycodone and Pregaba Plus Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include food rich in vitamin B and D in your diet.

  • Include cayenne pepper in your diet as it can help in lowering neuropathic pain.

  • Exercising regularly helps in improving overall health and combating pain.

  • Rest well, get plenty of sleep.

  • Try taking a warm bath as it can be soothing.

  • Avoid smoking and alcohol consumption.

  • Meditation and yoga can help lower stress, decrease pain sensitivity, and improves coping skills.

  • Acupuncture can be helpful by stimulating pressure points.

  • Using essential oils for massages can help increase circulation.

 

Habit Forming

Yes

Therapeutic Class

ANTICONVULSANT
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Alcohol

Caution

Alcohol may worsen the condition by increasing the risk of side-effects.

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Pregnancy

Unsafe

Pregaba Plus Capsule is a category C medicine. It is not recommended for use in pregnant women unless the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Caution

Pregaba Plus Capsule should be used with caution in breastfeeding mothers unless the doctor thinks the benefits outweigh the risks.

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Driving

Caution

Pregaba Plus Capsule may cause dizziness and drowsiness. So, avoid driving or operating heavy machinery while using Pregaba Plus Capsule.

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Liver

Caution

Pregaba Plus Capsule should be used with caution in patients with liver diseases. Dose adjustments may be necessary.

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Kidney

Caution

Pregaba Plus Capsule should be used with caution in patients with kidney diseases. Dose adjustments may be necessary

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Children

Unsafe

Pregaba Plus Capsule is not recommended for anyone below the age of 18 years.

Have a query?

FAQs

Pregaba Plus Capsule is used in the treatment of neuropathic pain, a chronic (long-term) progressive nerve disease that causes nerve pain due to nerve damage or the nervous system&amp;#039;s malfunctioning.

Pregaba Plus Capsule is a combination of two medicines: Pregabalin and Methylcobalamin. Pregaba Plus Capsule block the brain&amp;#039;s pain signals and protect nerve cells from further damage, thereby improving nerve signal conduction to the whole body parts. These effects help to reduce pain in patients with neuropathic pain.

Pregaba Plus Capsule should not be given to children and adolescents under the age of 18 years as it may increase suicidal thoughts.

Pregaba Plus Capsule should not be stopped abruptly as it may cause withdrawal reactions such as trouble sleeping, headache, nausea, feeling anxious, diarrhea, flu-like symptoms, convulsions, nervousness, depression, pain, sweating, and dizziness. Pregaba Plus Capsule should be stopped gradually over a minimum of 1 week.

Pregaba Plus Capsule can be used in patients with diabetes if they have neuropathic pain. However, inform your doctor if you notice any weight gain while using Pregaba Plus Capsule. Your doctor may change your diabetic medicines to stop weight gain. Also, take some measures to control weight such as eating a balanced diet and exercising regularly.

Pregaba Plus Capsule may cause drowsiness. So, it is advised to refrain from activities such as driving or operating heavy machinery if you feel sleepy after taking Pregaba Plus Capsule.

You may notice pain improvement within 2-3 days after taking Pregaba Plus Capsule. However, it may take 2-3 months for your symptoms to improve depending on your health condition.

Pregaba Plus Capsule may increase your appetite, which might make you eat more, and thus increases the risk of weight gain. However, it’s easier to prevent weight gain than losing the weight. Try to eat a healthy balanced diet. Avoid consuming high-calorie foods, such as soft drinks, chips, oily food, biscuits, cakes, and sweets. If you feel hungry between meals, do not eat junk food, instead eat vegetables, fruits, and low-calorie foods. Regular exercise helps to prevent weight gain. If you still have any concerns, discuss with your doctor.

Pregaba Plus Capsule may rarely cause serious side effects such as allergic reaction, suicidal thoughts or swelling of limbs (legs, hands, or feet). If you experience any signs of these side effects, discontinue Pregaba Plus Capsule and consult your doctor. Signs of an allergic reaction include swelling of your face, lips, mouth, tongue, gums, and neck. Allergic reactions can also lead to skin rash, difficulty breathing, hives (raised bumps) or blisters. Watch out for any changes, especially sudden changes in behaviors, mood, thoughts or feelings, or if you have suicidal thoughts.

Pregaba Plus Capsule may show an initial benefit after 2 weeks of taking it. However, for full benefits, it may take around 2 to 3 months or more (in some patients).

If you forget to take a dose of Pregaba Plus Capsule, take it as soon as you remember. But, if it is time for your next dose, skip the missed dose and take your regular dose. Do not take a double dose to make up for a forgotten dose.

No, taking a higher than the recommended dose may not be more effective, rather it may increase the risk of toxicity and serious side effects. If your symptoms are not relieved or there is an increased severity of your symptoms after using the recommended doses, please consult your doctor.

You are advised to avoid alcohol consumption while taking Pregaba Plus Capsule as it may increase the risk of side effects. However, if you have any concerns, please discuss with your doctor.

If you have started taking Pregaba Plus Capsule, you may need to see your doctor regularly. However, if the recommended doses does not improve your symptoms or if the side effects persist or worsen which affect your routine activities, consult your doctor.

Store Pregaba Plus Capsule at room temperature in a cool place. Protect from light and moisture. Keep it out of reach of children.

The side effects of Pregaba Plus Capsule include nausea, vomiting, headache, dizziness, drowsiness, increased appetite, weight gain and vision problems. If these side effects persist or worsen, please consult your doctor.

You are recommended to take Pregaba Plus Capsule only if it is advised by your doctor. Therefore, if you are pregnant or planning pregnancy, take your doctor’s advice.

You are recommended to avoid driving or using any tools or machines until you know how Pregaba Plus Capsule affects you as it may cause dizziness or drowsiness in some people.

Country of origin

India
Other Info - PR56421

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