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compositionComposition:PROGESTERONE-50MG
prescriptionPrescription Medicine

Pregafem AQ 50 Injection 1 ml is used in the treatment of dysfunctional uterine bleeding threatened abortion, and amenorrhoea. It is also used in the maintenance of early pregnancy. This medicine contains progesterone, a female hormone which helps increase the progesterone levels in the body. Common side effects include injection site reactions, rash or any other allergy, changes in the breast, darkening of facial skin, scalp hair loss, coarsening of hair in abnormal regions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

PROGESTERONE-50MG

Manufacturer/Marketer :

Uniza Healthcare Llp

Consume Type :

Parenteral

Return Policy :

Not Returnable

About Pregafem AQ 50 Injection 1 ml

Pregafem AQ 50 Injection 1 ml is used to treat various conditions like early pregnancy maintenance, dysfunctional uterine bleeding, and threatened abortion. Besides this, it can also be used for the progesterone withdrawal test in the endocrinal evaluation of secondary amenorrhoea (paused or missed periods)

Pregafem AQ 50 Injection 1 ml contains progesterone, which works by increasing levels of the progesterone hormone in your body.

In some cases, you may experience injection site reactions, changes in the breast, darkening of facial skin, scalp hair loss, nausea, fever, and sleep disturbances. Most of these side effects do not require medical attention and resolve over time. However, if the side effects persist, please consult your doctor.

Pregafem AQ 50 Injection 1 ml will be administered by a healthcare professional; do not self-administer. This medicine is intended for use in female (women) patients only. Hence not recommended for use in men.

Let your doctor know if you are allergic to any component of Pregafem AQ 50 Injection 1 ml. Inform your doctor if you have a blood clot caused by swollen veins (thrombophlebitis), a blocked blood vessel (thromboembolic disorder), a stroke, a suspected vaginal infection, the use of any other vaginal application products, or any ongoing medical conditions such as cancer of the breasts or genital organs. Also inform your doctor if you are pregnant, planning for pregnancy or breastfeeding before receiving this medicine.

Uses of Pregafem AQ 50 Injection 1 ml

Pregafem AQ 50 Injection 1 ml is used in the maintenance of early pregnancy and treatment of dysfunctional uterine bleeding, threatened abortion, and amenorrhea. The detailed uses of Pregafem AQ 50 Injection 1 ml are as follows:

  • Menstrual Cycle Regulation: Pregafem AQ 50 Injection 1 ml helps to regulate irregular menstrual cycles, treating conditions like amenorrhea by stabilising hormonal imbalances and promoting a regular menstrual cycle.
  • Treatment of Abnormal Uterine Bleeding: By controlling hormone levels and possibly lowering excessive bleeding during menstruation, Pregafem AQ 50 Injection 1 ml can help manage abnormal uterine bleeding.
  • Luteal Phase Support: Pregafem AQ 50 Injection 1 ml is prescribed to support the luteal phase during assisted reproductive technologies like in vitro fertilisation (IVF), increasing the chances of pregnancy.
     

Key Benefits

  • Pregafem AQ 50 Injection 1 ml is used to maintain early pregnancy in cases of documented history of repeated miscarriages due to luteal phase defect
  • This medicine is also used as an adjunct to successful infertility treatment with techniques such as in vitro fertilisation (IVF) or gamete intra-fallopian transfer (GIFT) to facilitate uterine implantation of the fertilised ovum.
  • In cases of secondary amenorrhoea (paused or missed periods), it can also be used as a progesterone withdrawal test to assess oestrogen priming.
  • Furthermore, it can treat threatening abortions and dysfunctional uterine haemorrhages.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.
  • The doctor or healthcare professional will administer Pregafem AQ 50 Injection 1 ml.
  • Pregafem AQ 50 Injection 1 ml is intended for use by women only.
  • Do not self-administer.

How Pregafem AQ 50 Injection 1 ml Works

Pregafem AQ 50 Injection 1 ml contains progesterone; it works by increasing levels of the progesterone hormone in your body.
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Alcohol

Consult your doctor

It is not known if alcohol affects Pregafem AQ 50 Injection 1 ml. In case of any concerns, discuss them with the doctor. However, it is advisable not to take or limit alcohol as a precautionary measure.

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Pregnancy

Consult your doctor

Pregafem AQ 50 Injection 1 ml is used in pregnancy conditions like threatened abortion, luteal phase support, and maintenance of pregnancy. Your doctor will weigh the benefits to outweigh the risks before prescribing this medicine.

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Breast Feeding

Consult your doctor

Let your doctor know if you are a nursing mother before receiving Pregafem AQ 50 Injection 1 ml; your doctor will decide whether Pregafem AQ 50 Injection 1 ml can be taken by breastfeeding mothers or not.

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Driving

Unsafe

Avoid driving or operating machinery if you experience drowsiness after receiving this injection.

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Liver

Consult your doctor

Inform your doctor before receiving the Pregafem AQ 50 Injection 1 ml if you have a history of or ongoing liver disease.

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Kidney

Consult your doctor

Inform your doctor before receiving the Pregafem AQ 50 Injection 1 ml if you have renal insufficiency or kidney problems. This medicine is excreted through urine, and if you have kidney problems, it may worsen your condition. Your doctor will adjust the dose of this medicine if required based on your condition.

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Children

Unsafe

Pregafem AQ 50 Injection 1 ml is not recommended for use in children.

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Heart

Caution

Pregafem AQ 50 Injection 1 ml should be used with caution in people with heart conditions, as it may increase the risk of heart attack, stroke, or blood clots when combined with estrogen therapy. Always consult your doctor to evaluate the risks and determine if it's safe for your specific cardiac profile.

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Geriatrics

Caution

Geriatric patients can receive Pregafem AQ 50 Injection 1 ml, but it may be more sensitive to side effects like blood clots, fluid retention, or changes in mood. It's important to use it under close medical supervision with individualized dosing.

What if I have taken an overdose of Pregafem AQ 50 Injection 1 ml

Pregafem AQ 50 Injection 1 ml is administered by a health care professional in a hospital setting. Hence, the chances of overdose are less. Seek immediate medical attention if you experience any of the following symptoms: difficulty speaking, pain, swelling, or warmth in the groin or calf, shortness of breath or rapid breathing, sudden or severe headaches, sudden dizziness or fainting, unusual sweating, or pain in the chest, jaw, or left arm.

Diet & Lifestyle Advise

  • Do regular exercise and physical activity to minimize hot flushes and improve sleep. Aerobics, yoga, and activities like tai chi may help relax the body and mind.
  • Try to wear loose clothes before going to bed and sleep in a cool, well-ventilated room. Doing this can prevent symptoms of hot flushes and night sweats. Sleep at least for 8 hours.
  • Avoid or limit intake of caffeine-containing beverages, alcohol, and spicy food, as these are known triggering agents for hot flushes.
  • Try to be stress-free to improve your mood swings due to hormonal fluctuations.
  • Quit smoking as it will help to reduce hot flushes and your risk of developing chronic conditions like heart disease, stroke, and cancer.

Have a query?

How Soon It Starts Working

The time required for Pregafem AQ 50 Injection 1 ml to start to work: The onset time of Pregafem AQ 50 Injection 1 ml has not been clinically established. 

The time for which the effects of Pregafem AQ 50 Injection 1 ml last: The duration of Pregafem AQ 50 Injection 1 ml’s effect is clinically not established.

What if you forget to take Pregafem AQ 50 Injection 1 ml

As this medicine is administered in a hospital by your healthcare professional, the chances of missing a dose are less. However, if you have any concerns, contact your doctor.

Storage

• Store in a cool and dry place away from sunlight.• Keep out of sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Please tell your doctor if you are allergic to Pregafem AQ 50 Injection 1 ml or any other medicines.
  • Inform your doctor if you are diagnosed with porphyria (a disorder in the formation of red blood pigment), cancers in breasts or genital organs, a blocked blood vessel, vaginal infections, and missed abortion.
  • If you are pregnant, planning for pregnancy or breastfeeding, please consult a doctor before taking Pregafem AQ 50 Injection 1 ml.
  • Pregafem AQ 50 Injection 1 ml is not recommended for children below 18 years of age.
  • This medicine is intended for use in female (women) patients only. Hence not recommended for use in men.

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Drug-Drug Interactions: Pregafem AQ 50 Injection 1 ml may interact with medicines used to treat certain menstrual problems (e.g. bromocriptine), medications to prevent transplant rejection (e.g. cyclosporine), and antifungal drugs (e.g. ketoconazole)

Drug- Food Interactions: No interactions found.

Drug-Disease Interactions: Pregafem AQ 50 Injection 1 ml may interact with disease conditions, including vaginal infection, vaginal bleeding, thrombophlebitis (a blood clot due to swollen veins), thromboembolic disorder (a blocked blood vessel) or a stroke, eye disorders, hypertension, cardiac disease, renal disease, diabetes, liver disease, migraine, porphyria or photosensitivity, epilepsy, depression, porphyria (a condition in the formation of red blood pigment), cancers in breasts or genital organs, and people with missed abortion.

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Habit Forming

No

Therapeutic Class

[HORMONES]

FAQs

Pregafem AQ 50 Injection 1 ml is used to treat various medical conditions, including early pregnancy maintenance, dysfunctional uterine bleeding, and threatened abortion. Besides this, it can also be used for the progesterone withdrawal test in the endocrinal evaluation of secondary amenorrhoea (paused or missed periods) to judge oestrogen priming.

Pregafem AQ 50 Injection 1 ml contains progesterone; it works by increasing levels of the hormone progesterone in your body.

The most prevalent negative effect of using Pregafem AQ 50 Injection 1 ml is the darkening of the facial skin. Please report to the doctor immediately if you notice any significant or rapid changes.

Using Pregafem AQ 50 Injection 1 ml is contraindicated in people with cancers such as breast or genital organs. So, inform your doctor if you have cancer in your breasts or genital organs.

Pregafem AQ 50 Injection 1 ml is contraindicated in people allergic to progesterone or people diagnosed with porphyria (a disorder in the formation of red blood pigment), cancers in breasts or genital organs, or a blocked blood vessel, vaginal infections, and/or people with missed abortion.

Hair loss is the most prevalent negative effect of utilizing Pregafem AQ 50 Injection 1 ml. If you notice any significant or abnormal hair loss, please immediately report it to the doctor.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

C-401, Ganesh Meridian, Opp. Gujarat High Court, Sarkhej - Gandhinagar Hwy, Sola, Ahmedabad, Gujarat 380060
Other Info - PRE2598
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