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Pregalin X SR 75 Tablet is used in the treatment of neuropathic pain. It contains Pregabalin and Methylcobalamin, which decreases the pain signals and helps rejuvenate and protect damaged nerve cells. It may cause common side effects such as dizziness, drowsiness, headache, loss of appetite, nausea or vomiting, diarrhea, headache, vision problems, and sweating. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
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More about the Product

Manufacturer/Marketer :

Torrent Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Pregalin X SR 75 Tablet

Pregalin X SR 75 Tablet is a prescription oral medicine used to manage neuropathic pain, which is nerve pain caused by damage or injury to your nerves. It is commonly prescribed for conditions such as diabetic neuropathy, shingles pain (postherpetic neuralgia), or nerve pain from spinal cord injuries. By targeting overactive nerve pathways, this medication helps quiet down abnormal pain signals and supports natural nerve recovery.

For the best results, you should take Pregalin X SR 75 Tablet consistently at the same times every day as directed by your doctor. You can take this medication with or without food, swallowing the capsule or tablet whole with a glass of water. Making healthy lifestyle choices, such as maintaining stable blood sugar levels and staying physically active, can significantly improve your treatment results.

While using Pregalin X SR 75 Tablet , some people may experience mild side effects like drowsiness, dizziness, or dry mouth. However, you should consult your doctor immediately if you face more serious issues, such as unexplained muscle pain, sudden mood changes, or severe swelling in your hands or feet.

Talk to your doctor before starting this medicine if you have a history of kidney disease, heart failure, or severe allergies. Do not take this if you have had a severe allergic reaction to pregabalin, methylcobalamin, or any other ingredients in this formulation.

This medication can interact with other substances like alcohol, sleeping pills, or anxiety medicines, which can dangerously increase drowsiness. If you are pregnant, breastfeeding, planning to become pregnant, or are an elderly individual, consult your doctor or pharmacist before taking this medicine to ensure it is safe for you.

Uses of Pregalin X SR 75 Tablet

Doctors prescribe Pregalin X SR 75 Tablet to treat several conditions involving nerve discomfort and damage. Key uses include:

  • Diabetic Neuropathy: Pregalin X SR 75 Tablet helps relieve chronic, burning, or tingling pain in the hands and feet caused by nerve damage from high blood sugar.
  • Postherpetic Neuralgia: It provides relief from persistent nerve pain that can linger after a shingles infection has healed.
  • Spinal Cord Injury Pain: Pregalin X SR 75 Tablet helps manage chronic neuropathic pain resulting from spinal cord damage.
  • Fibromyalgia: It helps reduce widespread muscle pain, stiffness, and sensitivity throughout the body.
     

Key Benefits

Pregalin X SR 75 Tablet is designed to help you regain comfort and improve your overall quality of life. By addressing both the symptoms and the underlying health of your nerves, this medicine offers key physical benefits:

  • Effective Pain Relief: It works quickly to quiet constant burning, stabbing, or shooting nerve sensations, allowing for easier, pain-free movement during the day.
  • Better Sleep Quality: Nerve pain often worsens at night, making it difficult to rest. By calming overactive nerves, this medicine helps you sleep more soundly.
  • Nerve Repair Support: It contains vital nutrients that help rebuild the protective coating of damaged nerves, promoting gradual healing and long-term recovery.

 

 

Side effects of Pregalin X SR 75 Tablet
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Wear compression garments like stockings, sleeves, or gloves to apply pressure and help stop fluid from building up, especially after the swelling goes down.
  • Move around and do exercises to help the fluid circulate, especially in swollen limbs. Ask your doctor for specific exercises.
  • Raise the swollen area above your heart level several times a day, even while sleeping, to help reduce swelling.
  • Gently massage the swollen area with firm but not painful pressure.
  • Keep the swollen area clean and moisturized to prevent injury and infection.
  • Reduce salt intake to help prevent fluid from building up and worsening the swelling, as advised by a doctor.
  • If the swelling does not get better after a few days of home treatment or worsens, consult your doctor right away.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Directions for Use

  • Take Pregalin X SR 75 Tablet with or without food or as advised by a doctor.
  • Recommended to take the medicine twice a day, in the morning and evening or as advised by your doctor.
  • Swallow the medicine as a whole with a glass of water.
  • Do not crush, break, or chew it.

How Pregalin X SR 75 Tablet Works

Pregalin X SR 75 Tablet combines two active ingredients that target nerve pain in complementary ways. Pregabalin belongs to a group of medicines called anticonvulsants. It works by binding to specific calcium channels in your brain and spinal cord. This action reduces the release of certain chemical messengers that carry pain signals through your nervous system, effectively turning down the 'volume' of the pain you feel. Methylcobalamin is a highly active form of vitamin B12. It plays a crucial role in producing myelin, which is the protective sheath that covers and insulates your nerve fibres. By supporting myelin production, it helps repair damaged nerve cells and restores proper nerve signal transmission.
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Alcohol

Caution

Alcohol may worsen the condition by increasing the risk of side-effects.

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Pregnancy

Unsafe

Pregalin X SR 75 Tablet is a category C medicine. It is not recommended for use in pregnant women unless the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Caution

Pregalin X SR 75 Tablet should be used with caution in breastfeeding mothers unless the doctor thinks the benefits outweigh the risks.

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Driving

Caution

Pregalin X SR 75 Tablet may cause dizziness and drowsiness. So, avoid driving or operating heavy machinery while using Pregalin X SR 75 Tablet .

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Liver

Caution

Pregalin X SR 75 Tablet should be used with caution in patients with liver diseases. Dose adjustments may be necessary.

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Kidney

Caution

Pregalin X SR 75 Tablet should be used with caution in patients with kidney diseases. Dose adjustments may be necessary

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Children

Unsafe

Pregalin X SR 75 Tablet is not recommended for anyone below the age of 18 years.

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Heart

Consult your doctor

Please inform your doctor if you have any pre-existing heart problems

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Geriatrics

Consult your doctor

Limited information available for use of Pregalin X SR 75 Tablet in elderly patients. Please consult your doctor.

What if I have taken an overdose of Pregalin X SR 75 Tablet

If you take more than your prescribed dose of Pregalin X SR 75 Tablet , seek emergency medical help immediately. Overdose symptoms may include severe drowsiness, confusion, agitation, or restlessness.

Diet & Lifestyle Advise

To support your nerve recovery while taking Pregalin X SR 75 Tablet , consider these evidence-based lifestyle changes:

  • Control blood sugar: If you have diabetes, carefully monitor and manage your blood sugar levels to prevent further nerve damage.
  • Eat a nutrient-rich diet: Incorporate foods high in B-vitamins, such as eggs, lean meats, poultry, and fortified cereals, to naturally support nerve health.
  • Stay physically active: Engage in low-impact exercises like walking, swimming, or light stretching to improve blood circulation to your nerves.
  • Check your feet daily: Nerve damage can reduce pain sensation in your feet. Inspect them regularly for cuts, blisters, or infections that you might not feel.
  • Avoid smoking and limit alcohol: Smoking reduces blood flow to the nerves, and alcohol can worsen nerve pain. Avoiding both can speed up your recovery.

 

health query

Have a query?

How Soon It Starts Working

The time required for Pregalin X SR 75 Tablet to start to work: The time required for Pregalin X SR 75 Tablet to show its action is not clinically established. The time for which the effects of Pregalin X SR 75 Tablet last: The duration of action for Pregalin X SR 75 Tablet is not clinically established.

What if you forget to take Pregalin X SR 75 Tablet

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and return to your regular schedule. Do not take a double dose to make up for a missed one.

Storage

•Store Pregalin X SR 75 Tablet at room temperature, ideally between 15°C and 30°C (59°F to 86°F). •Keep the medicine in its original container to protect it from moisture and direct light.

Drug Warnings

  • Do not drive immediately: Since this medicine can cause dizziness and drowsiness, avoid driving, riding a bicycle, or operating heavy machinery until you know how it affects you.
  • Do not stop taking this medicine suddenly: Stopping abruptly can cause withdrawal symptoms like nausea, headache, anxiety, or trouble sleeping. Your doctor will help you by gradually decreasing the dose.
  • Monitor your mental health: Pay close attention to any sudden changes in your mood or behaviour, and let a family member or doctor know immediately if you feel depressed.
  • Be cautious with alcohol: Drinking alcohol while taking this medicine can make you extremely drowsy and increase your risk of accidents.
     

Drug-Drug Interactions

verifiedApollotooltip
  • Central Nervous System Depressants: Taking Pregalin X SR 75 Tablet with medicines like opioid pain relievers, sleeping pills, or anxiety medications can lead to extreme drowsiness and dangerous breathing difficulties.
  • ACE Inhibitors: Combining this medicine with certain blood pressure medications (like lisinopril) may increase your risk of severe swelling (angioedema).
  • Antidiabetic Medications: Taking it alongside medicines like pioglitazone may increase the risk of weight gain and fluid retention.
     

Drug-Drug Interactions

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How does the drug interact with Pregalin X SR 75 Tablet:
Using Pregabalin together with Nalbuphine causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking Nalbuphine and Pregabalin together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Pregalin X SR 75 Tablet:
Co-administration of Ketamine with Pregabalin may increase the risk of side effects.

How to manage the interaction:
Although taking Pregabalin and Ketamine together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience symptoms such as dizziness, drowsiness, confusion, difficulty concentrating, or breathing difficulty, consult the doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Pregalin X SR 75 Tablet:
Using Tapentadol together with Pregabalin may cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Taking Pregabalin with Tapentadol can result in an interaction, it can be taken if a doctor has advised it. Contact a doctor immediately if you experience signs such as drowsiness, lightheadedness, palpitations, confusion, severe weakness, or difficulty breathing. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Pregalin X SR 75 Tablet:
Using Pregabalin together with Alfentanil causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking Pregabalin and Alfentanil together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience dizziness, drowsiness, difficulty concentrating, and impairment in judgment, reaction speed, and motor coordination, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Pregalin X SR 75 Tablet:
Using Pregabalin together with Methadone causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking methadone and pregabalin together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Pregalin X SR 75 Tablet:
Using Pregabalin together with Codeine may cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Codeine and Pregabalin together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Pregalin X SR 75 Tablet:
Using Pregabalin together with Buprenorphine causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Buprenorphine and Pregabalin together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, and impairment in judgment, reaction speed, and motor coordination, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Pregalin X SR 75 Tablet:
Using Pregabalin together with Hydromorphone causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Hydromorphone and pregabalin together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Pregalin X SR 75 Tablet:
Using Pregabalin together with Dezocine causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking Dezocine and Pregabalin together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Pregalin X SR 75 Tablet:
Using Pregabalin together with Fentanyl can increase the risk or severity of side effects.

How to manage the interaction:
Although taking Fentanyl together with Pregabalin can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you have dizziness, sleepiness, difficulty concentrating, or impairment in judgment. Do not stop taking any medication without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Alcohol: Avoid alcohol while taking this medicine, as it can severely worsen side effects like dizziness and coordination issues.
     
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

Yes

Therapeutic Class

[ANTICONVULSANT]

FAQs

Pregalin X SR 75 Tablet is used in the treatment of neuropathic pain, a chronic (long-term) progressive nerve disease that causes nerve pain due to nerve damage or the nervous system's malfunctioning.
Pregalin X SR 75 Tablet is a combination of two medicines: Pregabalin and Methylcobalamin. Pregalin X SR 75 Tablet block the brain's pain signals and protect nerve cells from further damage, thereby improving nerve signal conduction to the whole body parts. These effects help to reduce pain in patients with neuropathic pain.
Pregalin X SR 75 Tablet should not be given to children and adolescents under the age of 18 years as it may increase suicidal thoughts.
Pregalin X SR 75 Tablet should not be stopped abruptly as it may cause withdrawal reactions such as trouble sleeping, headache, nausea, feeling anxious, diarrhea, flu-like symptoms, convulsions, nervousness, depression, pain, sweating, and dizziness. Pregalin X SR 75 Tablet should be stopped gradually over a minimum of 1 week.
Pregalin X SR 75 Tablet can be used in patients with diabetes if they have neuropathic pain. However, inform your doctor if you notice any weight gain while using Pregalin X SR 75 Tablet . Your doctor may change your diabetic medicines to stop weight gain. Also, take some measures to control weight such as eating a balanced diet and exercising regularly.
Pregalin X SR 75 Tablet may cause drowsiness. So, it is advised to refrain from activities such as driving or operating heavy machinery if you feel sleepy after taking Pregalin X SR 75 Tablet .
You may notice pain improvement within 2-3 days after taking Pregalin X SR 75 Tablet . However, it may take 2-3 months for your symptoms to improve depending on your health condition.
Pregalin X SR 75 Tablet may increase your appetite, which might make you eat more, and thus increases the risk of weight gain. However, it’s easier to prevent weight gain than losing the weight. Try to eat a healthy balanced diet. Avoid consuming high-calorie foods, such as soft drinks, chips, oily food, biscuits, cakes, and sweets. If you feel hungry between meals, do not eat junk food, instead eat vegetables, fruits, and low-calorie foods. Regular exercise helps to prevent weight gain. If you still have any concerns, discuss with your doctor.
Pregalin X SR 75 Tablet may rarely cause serious side effects such as allergic reaction, suicidal thoughts or swelling of limbs (legs, hands, or feet). If you experience any signs of these side effects, discontinue Pregalin X SR 75 Tablet and consult your doctor. Signs of an allergic reaction include swelling of your face, lips, mouth, tongue, gums, and neck. Allergic reactions can also lead to skin rash, difficulty breathing, hives (raised bumps) or blisters. Watch out for any changes, especially sudden changes in behaviors, mood, thoughts or feelings, or if you have suicidal thoughts.
Pregalin X SR 75 Tablet may show an initial benefit after 2 weeks of taking it. However, for full benefits, it may take around 2 to 3 months or more (in some patients).
If you forget to take a dose of Pregalin X SR 75 Tablet , take it as soon as you remember. But, if it is time for your next dose, skip the missed dose and take your regular dose. Do not take a double dose to make up for a forgotten dose.
No, taking a higher than the recommended dose may not be more effective, rather it may increase the risk of toxicity and serious side effects. If your symptoms are not relieved or there is an increased severity of your symptoms after using the recommended doses, please consult your doctor.
If you have started taking Pregalin X SR 75 Tablet , you may need to see your doctor regularly. However, if the recommended doses does not improve your symptoms or if the side effects persist or worsen which affect your routine activities, consult your doctor.
Store Pregalin X SR 75 Tablet at room temperature in a cool place. Protect from light and moisture. Keep it out of reach of children.
The side effects of Pregalin X SR 75 Tablet include nausea, vomiting, headache, dizziness, drowsiness, increased appetite, weight gain and vision problems. If these side effects persist or worsen, please consult your doctor.
You are recommended to take Pregalin X SR 75 Tablet only if it is advised by your doctor. Therefore, if you are pregnant or planning pregnancy, take your doctor’s advice.
You are recommended to avoid driving or using any tools or machines until you know how Pregalin X SR 75 Tablet affects you as it may cause dizziness or drowsiness in some people.
It is highly recommended to avoid alcohol while taking this medicine. Alcohol can increase the risk of severe drowsiness, dizziness, and poor coordination. Talk to your doctor if you find it difficult to avoid alcohol.

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Country of origin

India

Manufacturer/Marketer address

Off. Ashram Road, Ahmedabad - 380 009., Gujarat, India
Other Info - PRE0283
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