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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Pregastar Plus Capsule is used in the management of neuropathic pain. It affects the chemicals in the brain that send pain signals to the nervous system thereby relieving nerve pain. It helps in the rejuvenation and protection of damaged nerve cells and also helps in delivering essential nutrients to the nerves. In some cases, you may experience certain common side effects such as dizziness, sleepiness, tiredness, nausea, and vomiting. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Manufacturer/Marketer :

Lupin Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Pregastar Plus Capsule

Pregastar Plus Capsule is used in the management of neuropathic pain. Neuropathic pain is a chronic progressive nerve disease that causes nerve pain due to nerve damage or a malfunctioning nervous system. Symptoms of neuropathic pain include shooting and burning pain followed by tingling and numbness (loss of sensation). Neuropathic pain can be caused by amputation of limbs, diabetic neuropathy (nerve damage due to excess blood sugar level), excessive alcohol intake (alcoholism) and cancer treatment via chemotherapy.

Pregastar Plus Capsule is a combination of five drugs: Pregabalin, Methylcobalamin, Alpha-lipoic acid, Pyridoxine, and Folic acid. Pregabalin affects the chemicals in the brain that send pain signals to the nervous system, thereby relieving nerve pain. Methylcobalamin and Pyridoxine help in the rejuvenation and protection of damaged nerve cells by producing a substance called myelin. Alpha-lipoic acid helps in providing a protective effect on the nerve tissues and brain. Folic acid helps in delivering essential nutrients to the nerves. Together, Pregastar Plus Capsule provides relief from neuropathic pain.

Take Pregastar Plus Capsule with or without food. Swallow Pregastar Plus Capsule as a whole with a glass of water; do not chew or break it. In some cases, you may experience certain common side effects, such as dizziness, sleepiness, tiredness, nausea, and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Consult your doctor if you are pregnant or breastfeeding. Pregastar Plus Capsule may cause drowsiness and dizziness, so drive only if you are alert. Pregastar Plus Capsule should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Pregastar Plus Capsule as it could lead to increased dizziness and sleepiness. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Pregastar Plus Capsule

Treatment of Neuropathic pain.

Directions for Use

Take Pregastar Plus Capsule with or without food. Swallow Pregastar Plus Capsule as a whole with a glass of water; do not chew or break it.

Medicinal Benefits

Pregastar Plus Capsule is a combination of five drugs: Pregabalin (anti-convulsant or antiepileptic), methylcobalamin (vitamin B12), alpha-lipoic acid (antioxidant), pyridoxine (vitamin B6), and folic acid (vitamin B9). Pregastar Plus Capsule is used to treat neuropathic pain. Pregabalin affects the chemicals in the brain that send pain signals to the nervous system, thereby relieving nerve pain. Methylcobalamin and Pyridoxine help in the rejuvenation and protection of damaged nerve cells by producing a substance called myelin. Alpha-lipoic acid helps in providing a protective effect on the nerve tissues and brain. Folic acid helps in providing essential nutrients to the nerves. Together, Pregastar Plus Capsule helps in providing relief from neuropathic pain.

How Pregastar Plus Capsule Works

Pregastar Plus Capsule is a combination of five drugs: Pregabalin, Methylcobalamin, Alpha-lipoic acid, Pyridoxine, and Folic acid. Pregabalin affects the chemicals in the brain that send pain signals to the nervous system, thereby relieving nerve pain. Methylcobalamin and Pyridoxine help in the rejuvenation and protection of damaged nerve cells by producing a substance called myelin. Alpha-lipoic acid helps in providing a protective effect on the nerve tissues and brain. Folic acid helps in delivering essential nutrients to the nerves. Together, Pregastar Plus Capsule provides relief from neuropathic pain.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Pregastar Plus Capsule

Do not take more than the prescribed dose of Pregastar Plus Capsule as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take Pregastar Plus Capsule if you are allergic to any of its contents. Inform your doctor if you have/had heart problems or bipolar syndrome. Consult your doctor if you are pregnant or breastfeeding. Pregastar Plus Capsule may cause drowsiness and dizziness, so drive only if you are alert. Pregastar Plus Capsule should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Pregastar Plus Capsule as it could lead to increased dizziness and sleepiness. Consult your doctor immediately if you experience suicidal tendencies. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Pregastar Plus Capsule:
Coadministration of Pregastar Plus Capsule and Carbamazepine may reduce the blood levels of Pregastar Plus Capsule.

How to manage the interaction:
Although there is a possible interaction between Pregastar Plus Capsule and Carbamazepine, you can take these medicines together if prescribed by your doctor. However, if your condition changes or you experience loss of seizure control, contact your doctor.
How does the drug interact with Pregastar Plus Capsule:
Coadministration of Pregastar Plus Capsule and Cholestyramine may interfere with the absorption of Pregastar Plus Capsule.

How to manage the interaction:
Although taking Cholestyramine and Pregastar Plus Capsule together can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience Constipation, Diarrhea, Stomach pain, Nausea, or Loss of appetite, consult a doctor. Do not stop using any medications without consulting a doctor.
How does the drug interact with Pregastar Plus Capsule:
Coadministration of Pregastar Plus Capsule and Fluorouracil may increase the effects of Fluorouracil and increase the risk of serious side effects such as bleeding problems, anaemia (lack of blood), infections, and nerve damage.

How to manage the interaction:
Although there is a possible interaction between Pregastar Plus Capsule and Fluorouracil, you can take these medicines together if prescribed by your doctor. However, if you experience diarrhoea, paleness of skin, severe nausea and vomiting, over-tiredness, dizziness, fainting, blood in the stools, unusual bleeding or bruising, fever, chills, body pains, flu-like symptoms, skin reactions, mouth ulcers or sores, and/or numbness, burning or tingling in your hands and feet, contact your doctor.
How does the drug interact with Pregastar Plus Capsule:
Co-administration of Pregastar Plus Capsule with Capecitabine may increase the risk of serious side effects such as bleeding problems, anemia, infections, and nerve damage.

How to manage the interaction:
Although there is a possible interaction between Pregastar Plus Capsule and Capecitabine, you can use these medicines together if prescribed by the doctor. However, if you experience paleness of skin, diarrhea, severe nausea and vomiting, over-tiredness, dizziness, fainting, blood in the stools, unusual bleeding or bruising, fever, chills, body aches, flu-like symptoms, skin reactions, mouth ulcers or sores, and/or numbness, burning or tingling sensation in the hands and feet, contact a doctor. Do not discontinue the medication without consulting a doctor. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Pregastar Plus Capsule:
Sulfadiazine may decrease the blood levels and effects of Pregastar Plus Capsule.

How to manage the interaction:
Although there is a possible interaction between Pregastar Plus Capsule and Sulfadiazine, you can take these medicines together if prescribed by your doctor.
How does the drug interact with Pregastar Plus Capsule:
Trimethoprim may decrease the blood levels and effects of Pregastar Plus Capsule.

How to manage the interaction:
Although there is a possible interaction between Pregastar Plus Capsule and Trimethoprim, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without consulting your doctor.
How does the drug interact with Pregastar Plus Capsule:
When Tramadol is used with Pregastar Plus Capsule, it may possibly lead to side effects such as respiratory difficulties, unconsciousness.

How to manage the interaction:
Although taking tramadol and Pregastar Plus Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinOxycodone
Severe
How does the drug interact with Pregastar Plus Capsule:
Using Pregastar Plus Capsule together with Oxycodone causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking oxycodone and Pregastar Plus Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinAlfentanil
Severe
How does the drug interact with Pregastar Plus Capsule:
Using Pregastar Plus Capsule together with Alfentanil causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking Pregastar Plus Capsule and Alfentanil together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience dizziness, drowsiness, difficulty concentrating, and impairment in- judgment, reaction speed and motor coordination, consult the doctor immediately. Avoid driving or operating dangerous machinery. Do not exceed the doses, frequency, or duration of usage advised by the doctor. Do not discontinue any medications without consulting a doctor.
PregabalinHydrocodone
Severe
How does the drug interact with Pregastar Plus Capsule:
Using Pregastar Plus Capsule together with Hydrocodone causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Hydrocodone and Pregastar Plus Capsule together can result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include food rich in vitamin B and D in your diet.

  • Include cayenne pepper in your diet as it can help in lowering neuropathic pain.

  • Exercising regularly helps in improving overall health and combating pain. 

  • Rest well, get plenty of sleep.

  • Try taking a warm bath as it can be soothing.

  • Avoid smoking and alcohol consumption.

  • Meditation and yoga can help lower stress, decrease pain sensitivity and improves coping skills.

  • Acupuncture can be helpful by stimulating pressure points.

  • Using essential oils for massages can help increase circulation.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Pregastar Plus Capsule as it may increase dizziness and sleepiness.

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Pregnancy

Caution

Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Pregastar Plus Capsule ; your doctor will decide whether Pregastar Plus Capsule can be taken by breastfeeding mothers or not.

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Driving

Caution

Pregastar Plus Capsule may cause drowsiness, sleepiness and tiredness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Pregastar Plus Capsule should not be given to children as the safety and efficacy have not been established.

Have a query?

FAQs

Pregastar Plus Capsule is used in the management of neuropathic pain.

Pregastar Plus Capsule may cause weight gain due to an increase in appetite. Maintain a healthy weight by regular exercise and following a proper diet.

To treat your condition effectually, continue taking Pregastar Plus Capsule for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Pregastar Plus Capsule ; your doctor will reduce the dose gradually.

Pregastar Plus Capsule can cause life-threatening breathing problems in patients with COPD and asthma. So a person with long paused breathing, blue coloured lips, or sleeping disorder should inform the doctor before use of Pregastar Plus Capsule .

Pregastar Plus Capsule can decrease the sperm count and may affect men's fertility. However, it is unclear whether these effects would occur. So it is advisable to ask your doctor about your risk.

No, Pregastar Plus Capsule is not a usual painkiller but is used in the management of neuropathic pain by providing essential nutrients to the nerves.

Pregastar Plus Capsule contains Pregabalin, Methylcobalamin, Alpha-lipoic acid, Pyridoxine, and Folic acid. Pregabalin affects the chemicals in the brain that send pain signals to the nervous system, thereby relieving nerve pain. Methylcobalamin and Pyridoxine help in the rejuvenation and protection of damaged nerve cells by producing a substance called myelin. Alpha-lipoic acid helps in providing a protective effect on the nerve tissues and brain. Folic acid helps in delivering essential nutrients to the nerves. Together, Pregastar Plus Capsule provides relief from neuropathic pain.

Yes, Pregastar Plus Capsule may make you feel drowsy or you cause you to fall asleep suddenly during your daily activities. Sometimes, you might not even feel sleepy or have any other warning signs before you fall asleep suddenly. Thus, avoid driving or operating machinery, working at heights or participating in potentially dangerous activities until you know how Pregastar Plus Capsule affects you. If you experience such episodes while taking Pregastar Plus Capsule , inform your doctor.

Pregastar Plus Capsule may rarely cause serious side effects such as allergic reaction, suicidal thoughts or swelling of limbs (legs, hands, or feet). If you experience any signs of these side effects, discontinue Pregastar Plus Capsule and consult your doctor. Signs of an allergic reaction include swelling of your face, lips, mouth, tongue, gums, and neck. Allergic reactions can also lead to skin rash, difficulty breathing, hives (raised bumps) or blisters. Watch out for any changes, especially sudden changes in behaviors, mood, thoughts or feelings, or if you have suicidal thoughts.

It may take about 2 weeks to experience the first benefit with Pregastar Plus Capsule . However, to see full effect, it may take around 2-3 months or it may take longer in some patients.

If you forget to take a dose of Pregastar Plus Capsule , take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue your regular dose. Do not double the dose to make up for the missed one as this may increase the risk of side effects.

If you suspect you have taken too much of Pregastar Plus Capsule , please contact your doctor immediately. Do this even if you have no signs of discomfort or poisoning.

No, taking a higher than the recommended dose may not be more effective, rather it may increase the risk of toxicity and serious side effects. If your symptoms are not relieved or there is an increased severity of your symptoms after using the recommended doses, please consult your doctor.

You are advised to avoid alcohol consumption while taking Pregastar Plus Capsule as it may increase the severity of dizziness and sleepiness. However, if you have any concerns, please discuss with your doctor.

If you have started taking Pregastar Plus Capsule , you may need to see your doctor regularly. However, if the recommended doses does not improve your symptoms or if the side effects persist or worsen which affect your routine activities, consult your doctor.

Store Pregastar Plus Capsule at room temperature in a cool and dry place. Protect from light and moisture. Keep it out of reach of children.

The side effects of Pregastar Plus Capsule include sleepiness, dizziness, drowsiness, tiredness, nausea and vomiting. If these side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India Country of Origin: India
Other Info - PRE0449

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