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compositionComposition:DOXYLAMINE-20MG+PYRIDOXINE (VITB6)-20MG
prescription
Prescription Medicine
info
Pregdox OD Tablet 10's

Pregdox OD Tablet 10's is used to treat nausea and vomiting during pregnancy. It contains Doxylamine and Pyridoxine (vitamin B6), which prevents the feeling of nausea and sickness in pregnant women. Besides this, it also provides nutrition to the body. It works by blocking the natural chemical (histamine) in the body, thereby preventing nausea and vomiting. In some cases, you may experience certain common side effects such as dizziness, stomach pain, constipation, and dry mouth. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

DOXYLAMINE-20MG+PYRIDOXINE (VITB6)-20MG

Manufacturer/Marketer :

Rekvina Pharmaceuticals

Consume Type :

Oral

Expires on or after :

Jan-29

Return Policy :

Not Returnable

About Pregdox OD Tablet 10's

Pregdox OD Tablet 10's is a prescription medicine used to treat nausea and vomiting during pregnancy (morning sickness). It is usually prescribed when lifestyle changes, vitamin B6 alone, or ginger have not provided enough relief. It helps pregnant women feel more comfortable and maintain adequate nutrition.

Take this medicine exactly as prescribed by your doctor, even if you are not feeling sick at that moment. Taking it regularly helps prevent nausea before it starts. Follow the instructions for your specific product, and eat small, frequent meals while drinking plenty of fluids to help manage symptoms.

Common side effects include drowsiness, dry mouth, and mild dizziness, which usually improve as your body adjusts. Contact your doctor if you experience severe drowsiness, difficulty staying awake, trouble passing urine, or any other unusual or persistent symptoms.

Before taking Pregdox OD Tablet 10's, tell your doctor if you have asthma, glaucoma, stomach or bladder blockage, or allergies to antihistamines. Do not use this medicine if you are taking monoamine oxidase inhibitors (MAOIs). Avoid alcohol and other medicines that cause drowsiness, and consult your doctor before breastfeeding.

Pregdox OD Tablet 10's has a well-established safety profile during pregnancy and is approved for treating pregnancy-related nausea and vomiting when used as directed by a healthcare professional. Your doctor will review your treatment regularly and advise when the medicine is no longer needed.

Uses of Pregdox OD Tablet 10's

Pregdox OD Tablet 10's used in the treatment of nausea and vomiting in pregnancy. The detailed uses of Pregdox OD Tablet 10's are as follows:

  • Nausea and vomiting of pregnancy: Pregdox OD Tablet 10's helps reduce the severity of morning sickness in pregnant women who have not found relief through dietary or lifestyle changes.

Key Benefits

  • Pregdox OD Tablet 10's brings physical comfort to expectant mothers by significantly reducing the constant feeling of nausea. This relief allows pregnant women to eat normally, digest their meals, and keep essential fluids down, reducing the risk of dehydration during a vital stage of pregnancy.
  • By preventing frequent vomiting, this medication also helps patients maintain their energy levels and perform their daily activities with minimal disruption.
  • It offers a reliable, clinically supported approach to managing one of the most physically challenging aspects of early pregnancy.

Directions for Use

  • Swallow the tablet whole with a full glass of water. Do not crush, chew, or split delayed-release tablets, as this can damage the special coating and release the medicine too quickly.
  • If you have been prescribed an immediate-release formulation, follow the instructions provided on your prescription label.
  • Follow your doctor's instructions regarding food. Immediate-release formulations are commonly taken on an empty stomach because food can delay absorption.
  • Delayed-release formulations are typically taken at bedtime according to prescribing guidelines. Always follow the instructions provided for your specific product.
  • If your symptoms do not improve, become worse, or you are unable to keep food or fluids down, contact your doctor. Do not change your dose without medical advice.

How Pregdox OD Tablet 10's Works

Pregdox OD Tablet 10's contains two active ingredients that work together to help prevent nausea and vomiting during pregnancy. • Doxylamine is an antihistamine that blocks histamine (H1) receptors and also blocks muscarinic receptors. This reduces the nerve signals that stimulate the brain's vomiting centre, helping to prevent nausea and vomiting. • Pyridoxine (vitamin B6) supports normal body functions and is clinically recognized for helping reduce nausea during pregnancy, although its exact anti-nausea mechanism is not fully understood. Together, these two ingredients help prevent symptoms before they begin when taken regularly as prescribed.
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Pregdox OD Tablet 10's. It could lead to increased dizziness and drowsiness.

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Pregnancy

Safe if prescribed

Pregdox OD Tablet 10's is intended for use in pregnant women. Please consult your doctor before taking Pregdox OD Tablet 10's.

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Breast Feeding

Unsafe

It is not recommended to take Pregdox OD Tablet 10's while you are breastfeeding. Pregdox OD Tablet 10's passes into breast milk.

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Driving

Caution

$nmae may cause dizziness, drowsiness and tiredness, do not drive or operate heavy machinery if you feel dizzy.

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Liver

Caution

Let your doctor know if you have any history of liver diseases or hepatic impairment when you are prescribed Pregdox OD Tablet 10's.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases when you are prescribed Pregdox OD Tablet 10's.

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Children

Unsafe

Pregdox OD Tablet 10's should not be used by children below 18 years of age, as the efficacy and safety have not been established.

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Heart

Unsafe

Pregdox OD Tablet 10's should be avoided in cardiac patients without doctor's prescription. However, if prescribed caution should be exercised.

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Geriatrics

Unsafe

Pregdox OD Tablet 10's is not recommended for use in elderly patients as it can lead to serious side effects.

What if I have taken an overdose of Pregdox OD Tablet 10's

In case of an accidental overdose, seek immediate medical attention or contact a poison control center right away. Symptoms of an overdose may include extreme drowsiness or inability to stay awake, confusion, agitation, dilated pupils, a very fast heartbeat, difficulty breathing, or seizures in severe cases. Seek emergency medical care immediately if an overdose is suspected.

Diet & Lifestyle Advise

  • Eat small, frequent meals throughout the day instead of three large meals to prevent your stomach from becoming completely empty, which can worsen nausea.
  • Keep plain crackers next to your bed and eat a few before getting up in the morning to settle your stomach.
  • Avoid greasy, fried, spicy, or very sweet foods, as these are common triggers for pregnancy-related nausea.
  • Sip clear, cold liquids like water, ginger tea, or clear broths slowly between meals to stay well-hydrated without overfilling your stomach.
  • Ensure your environment is well-ventilated to avoid strong cooking smells or perfumes that might trigger vomiting.
  • Before starting medication, or alongside it, simple measures such as eating small frequent meals, avoiding foods that trigger nausea, taking vitamin B6 supplements (if recommended by your doctor), and trying ginger-containing foods or drinks may help reduce mild morning sickness symptoms. If these measures are not enough, your doctor may prescribe Pregdox OD Tablet 10's.

Have a query?

How Soon It Starts Working

  • The time required for Pregdox OD Tablet 10's to start to work: Pregdox OD Tablet 10's ideally shows its action within 1 hour after administration.
  • The time for which the effects of Pregdox OD Tablet 10's last: The effect of Pregdox OD Tablet 10's lasts for 24 hours.

What if you forget to take Pregdox OD Tablet 10's

If you miss a dose of Pregdox OD Tablet 10's, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and return to your regular routine. Do not take two doses at the same time to make up for a missed one.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Always inspect your tablets before taking them; do not take any tablet that appears cracked, discolored, or damaged.
  • Do not drive, ride a bicycle, or operate any machinery after taking this medicine until you know exactly how sleepy it makes you feel.
  • Avoid drinking alcohol while using this medicine, as it can dangerously increase drowsiness and make you feel extremely dizzy.
  • Inform your doctor if you are scheduled for any allergy skin tests, as this medicine can affect the test results.
  • Keep a written log of when you take your doses to ensure you do not accidentally take too much medicine.

Drug-Drug Interactions

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Drug-Drug Interactions:

  • Monoamine oxidase inhibitors (MAOIs): Avoid using these medicines together unless specifically advised by your doctor. MAOIs may increase the effects of doxylamine, leading to excessive drowsiness, increased anticholinergic effects (such as dry mouth or difficulty urinating), and additive central nervous system depression.
  • Sedatives, sleeping medicines, opioid pain relievers, alcohol, or other medicines that cause drowsiness: Taking these together with Pregdox OD Tablet 10's may increase sleepiness, dizziness, impaired coordination, and, in some cases, slow or difficult breathing.

Drug-Food Interactions:

Food: For immediate-release formulations, taking the medicine with food may delay absorption and slow the onset of action. Delayed-release formulations should be taken exactly as directed, usually at bedtime. Follow your doctor's instructions for your prescribed product.

Drug-Disease Interactions:

  • Glaucoma: May increase pressure inside the eyes and worsen the condition.
  • Asthma or lung diseases: May dry up mucus in the airways, making it harder to clear secretions and breathe comfortably.
  • Urinary retention or stomach blockages: Can worsen bladder emptying problems or digestive tract blockages, making it more difficult to urinate or pass food through the stomach and intestines.
     
Doxylamine + Pyridoxine (vit b6)Tranylcypromine
Critical
Doxylamine + Pyridoxine (vit b6)Linezolid
Critical

Drug-Drug Interactions

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Doxylamine + Pyridoxine (vit b6)Tranylcypromine
Critical
How does the drug interact with Pregdox Od Tab:
Taking Doxylamine and Pyridoxine with tranylcypromine can increase the risk of severe side effects.

How to manage the interaction:
There may be a possibility of interaction between Doxylamine and Pyridoxine with Tranylcypromine, it can be taken if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, stomach cramps, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
Doxylamine + Pyridoxine (vit b6)Linezolid
Critical
How does the drug interact with Pregdox Od Tab:
Coadministration of Linezolid with Doxylamine and Pyridoxine might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to severe side effects.

How to manage the interaction:
Coadministration of Linezolid with Doxylamine and Pyridoxine is avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience shivering, blurred vision, stomach cramps, vomiting, and diarrhea contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
Doxylamine + Pyridoxine (vit b6)Fentanyl
Severe
How does the drug interact with Pregdox Od Tab:
Taking Doxylamine and Pyridoxine with Fentanyl can increase the risk of side effects.

How to manage the interaction:
Co-administration of Doxylamine and Pyridoxine with Fentanyl can result in an interaction, it can be taken if a doctor has advised it. Consult your doctor immediately if you feel drowsiness, shortness of breath, or palpitations. Do not stop taking any medication without consulting your doctor.
Doxylamine + Pyridoxine (vit b6)Sodium oxybate
Severe
How does the drug interact with Pregdox Od Tab:
Coadministration of Sodium oxybate with Doxylamine and Pyridoxine can increase the risk or severity of side effects.

How to manage the interaction:
Coadministration of Sodium oxybate with Doxylamine and Pyridoxine can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any shortness of breath, palpitations, muscle spams, or chest pain, contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
Doxylamine + Pyridoxine (vit b6)Hydrocodone
Severe
How does the drug interact with Pregdox Od Tab:
Coadministration of Hydrocodone with Doxylamine and Pyridoxine can increase the risk of side effects.

How to manage the interaction:
Coadministration of Hydrocodone with Doxylamine and Pyridoxine can result in an interaction, it can be taken if your doctor has advised it. However, if you experience palpitations, fever, excessive sweating, muscle stiffness, stomach cramps, vomiting, and diarrhea contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
Doxylamine + Pyridoxine (vit b6)Potassium citrate
Severe
How does the drug interact with Pregdox Od Tab:
Taking Doxylamine and Pyridoxine with Potassium citrate can increase the risk of stomach inflammation or ulcers.

How to manage the interaction:
There may be a possibility of interaction between Doxylamine and Pyridoxine with Potassium citrate, it can be taken if prescribed by a doctor. However, if you experience severe stomach pain, vomiting, bloating, or tarry stools, consult the doctor immediately. Do not discontinue any medications without consulting the doctor.
Doxylamine + Pyridoxine (vit b6)Ketamine
Severe
How does the drug interact with Pregdox Od Tab:
Coadministration of Ketamine with Doxylamine and Pyridoxine can increase the risk of side effects.

How to manage the interaction:
Coadministration of Ketamine with Doxylamine and Pyridoxine can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIEMETICS]

FAQs

Pregdox OD Tablet 10's is used to treat nausea and vomiting during pregnancy.
Pregdox OD Tablet 10's is a combination of two drugs, namely: Doxylamine and Pyridoxine (vitamin B6) used to treat nausea and vomiting during pregnancy. Besides this, it also provides nutrition to the body. Doxylamine belongs to the class of antihistamines that works by blocking the natural chemical (histamine) in the body, thereby preventing nausea and vomiting. Pyridoxine(vitamin B6) is a form of the vitamin. Vitamin B6 deficiency may cause nausea and vomiting during pregnancy. Pyridoxine works by increasing the level of vitamin B6 in the body and treat nausea and vomiting during pregnancy.
If you or someone else have taken too much of Pregdox OD Tablet 10's, contact your doctor or nearest hospital casualty department.
Pregdox OD Tablet 10's causes dizziness and sleepiness. Drive only if you are alert and omit driving and operating machinery if you feel dizzy or sleepy.
Do not discontinue Pregdox OD Tablet 10's without consulting your doctor. To treat your condition effectually continue taking Pregdox OD Tablet 10's for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Pregdox OD Tablet 10's.
Common side effects of Pregdox OD Tablet 10's include dizziness, stomach pain, constipation, dry mouth. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.
You should take Pregdox OD Tablet 10's in the dose and duration prescribed by your doctor. Generally, it is recommended to take it once a day at bedtime. However, if your symptoms do not improve, your doctor may recommend taking it two or three times a day. Do not exceed the recommended dose without consulting your doctor.
Pregdox OD Tablet 10's is used to relieve nausea and vomiting during pregnancy (morning sickness). However, outside of pregnancy, Pregdox OD Tablet 10's is not commonly recommended as a first-line treatment for vomiting. Please consult a doctor to determine the cause and the appropriate treatment.
Pregdox OD Tablet 10's may cause drowsiness or sleepiness as a side effect in some individuals. It is advised to avoid activities that require full alertness, such as driving or operating machinery while using Pregdox OD Tablet 10's. If the side effect persists, please consult your doctor.
Pregdox OD Tablet 10's is contraindicated in individuals who are allergic to any of its ingredients. It should not be taken by breastfeeding mothers, as it passes into breast milk. Also, Pregdox OD Tablet 10's should be avoided in patients who are taking monoamine oxidase inhibitors (MAOIs) or have a history of certain psychiatric disorders, as it may make side effects worse and last longer, even leading to death.
It is not recommended to exceed the recommended dose of Pregdox OD Tablet 10's without consulting your doctor. Taking more than the recommended dose or using it for a long time may increase the risk of side effects such as drowsiness, dizziness, stomach pain, or dry mouth. Always follow your doctor's instructions to minimize the risks.
Store the tablets at room temperature, ideally between 20°C to 25°C (68°F to 77°F). Keep the medicine in its original container to protect it from light, heat, and moisture. Do not store it in bathroom cabinets where humidity levels change frequently. Never freeze this medication. Keep all packages safely out of the reach of children and pets. Do not throw away expired or unused medication in your household trash or flush it down the toilet. Ask your pharmacist about safe local medicine take-back programs.
It depends on the formulation. Immediate-release products are commonly taken on an empty stomach because food may delay absorption. Delayed-release formulations are usually taken at bedtime according to the prescribing information. Always follow the instructions provided for your prescribed product and ask your doctor or pharmacist if you are unsure.
This medicine is specifically approved for managing morning sickness during pregnancy. However, your doctor will regularly evaluate your health to determine if you still need it. Talk to your doctor about how long you should continue taking this medication.
It is generally not recommended to breastfeed while taking this medicine. The active components can pass into breast milk and may cause sleepiness, irritability, or breathing problems in a nursing baby. Talk to your doctor to discuss safer alternatives.
If your symptoms do not improve or if they get worse, do not increase your dose on your own. Your doctor may need to adjust your treatment plan or check for other pregnancy-related conditions. Talk to your doctor to find the best solution for you.
While moderate caffeine intake is generally acceptable for many pregnant individuals, hot liquids or large amounts of fluids can sometimes trigger nausea. Be cautious and talk to your doctor about your diet and fluid intake while managing morning sickness.
Morning sickness is common during early pregnancy and usually causes mild to moderate nausea and occasional vomiting that can often be managed with dietary changes or medicines such as Pregdox OD Tablet 10's. Hyperemesis gravidarum is a much more severe condition that causes persistent vomiting, dehydration, weight loss, and difficulty keeping food or fluids down. It often requires prompt medical care, intravenous fluids, and additional treatments. Contact your doctor immediately if you are unable to keep fluids down, feel faint, or notice signs of dehydration.

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Country of origin

India

Manufacturer/Marketer address

328, Paradise Complex,Sayajigunj,Baroda - 390 005. (Gujarat) India.
Other Info - PRE0400

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