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Progivian-AQ 50 mg Injection 2.237 ml is used in the treatment of dysfunctional uterine bleeding threatened abortion, and amenorrhoea. It is also used in the maintenance of early pregnancy. This medicine contains progesterone, a female hormone which helps increase the progesterone levels in the body. Common side effects include injection site reactions, rash or any other allergy, changes in the breast, darkening of facial skin, scalp hair loss, coarsening of hair in abnormal regions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

PROGESTERONE-50MG

Manufacturer/Marketer :

Nivian Life Sciences Pvt Ltd

Consume Type :

Parenteral

Return Policy :

Not Returnable

About Progivian-AQ 50 mg Injection 2.237 ml

Progivian-AQ 50 mg Injection 2.237 ml is an injectable hormone helper prescribed to treat irregular or missed menstrual periods and abnormal uterine bleeding caused by a lack of natural hormones. It is also commonly used to support early pregnancy in women undergoing fertility treatments. This injection helps prepare and maintain the lining of the uterus so that a fertilized egg can implant and grow.

You will typically receive this injection once a day or on specific days of your menstrual cycle, depending on your treatment plan. Since it is given as an injection, your food intake does not affect how the medicine is absorbed, but maintaining a consistent schedule is highly important for its effectiveness. Making simple lifestyle adjustments, such as managing stress levels and maintaining a stable sleep routine, can support your body's hormonal balance during treatment.

While using this medication, you may experience mild side effects like breast tenderness, headache, or temporary pain at the injection site. However, if you experience severe symptoms such as sudden shortness of breath, severe leg swelling, or vision changes, you must contact your doctor immediately.

Do not take this if you have a history of blood clots, severe liver damage, breast or genital tract cancers, or unusual vaginal bleeding that a doctor has not evaluated. It is crucial to discuss your complete medical history with your doctor before starting therapy, especially if you have asthma, epilepsy, migraine headaches, or heart problems.

This injection can interact with certain medications, including those that affect liver enzymes, so you must share your full medication list with your healthcare provider. You should also avoid smoking and limit alcohol consumption while on this therapy, as they can increase your risk of blood clots. If you are pregnant, planning to become pregnant, or breastfeeding, consult your healthcare provider to ensure this treatment is safe and appropriate for your specific needs.

Uses of Progivian-AQ 50 mg Injection 2.237 ml

Progivian-AQ 50 mg Injection 2.237 ml is used to correct Progivian-AQ 50 mg Injection 2.237 ml deficiency, regulate menstrual cycles, and support pregnancy during fertility treatment.

  • Treating absence of menstrual periods (amenorrhea): It helps restore a regular menstrual cycle in women who have stopped having periods due to low hormone levels.
  • Managing abnormal uterine bleeding: It regulates the monthly shedding of the uterine lining to control unusual or heavy bleeding caused by hormonal imbalances.
  • Supporting assisted reproductive technology (ART): It helps prepare the womb and supports early pregnancy during fertility procedures like in vitro fertilization (IVF).

Key Benefits

Progivian-AQ 50 mg Injection 2.237 ml helps restore hormonal balance, support healthy uterine function, and improve the chances of a successful pregnancy during fertility treatment.

  • Restores regular menstrual cycles: Helps regulate the menstrual cycle by correcting Progivian-AQ 50 mg Injection 2.237 ml deficiency, making periods more predictable.
  • Controls abnormal uterine bleeding: Supports normal shedding of the uterine lining, helping reduce heavy, prolonged, or irregular menstrual bleeding.
  • Supports fertility treatment: Prepares the uterine lining for embryo implantation and helps maintain a favourable environment during the early stages of pregnancy.
  • Protects the uterine lining: Prevents excessive thickening of the endometrium caused by hormonal imbalance, supporting long-term uterine health.
Side effects of Progivian-aq 50mg Inj 2.237ml
  • Regular activity including cardio and weightlifting can help in weight loss and breast tissue reduction.
  • Limit alcohol intake to lower your chances of gynecomastia and hormonal changes.
  • Eat a balanced diet and avoid foods high in estrogen-like compounds.
  • Follow your doctor's instructions take medication consistently to reduce breast enlargement and do not stop taking medication on your own.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Mood swings can be managed but cannot be controlled. Therefore, spending time in nature can help you feel light and improve your mood.
  • Practice meditation, deep breathing and do regular exercise that can positively affect your mood. Also helps in processing the situation before responding to it.
  • Food has direct impact on mood. Therefore, eat foods that are less processed and reduce sugar intake.
  • Consult your doctor if the mood swings are uncontrollable or unmanageable.
  • Always wear loose-fitting clothes suitable for your activity during hot flashes.
  • Include a diet containing fruits like watermelon, grapes, bananas and green leafy vegetables.
  • Drink plenty of water and stay hydrated.
  • Stay calm and lower your anxiety by practising yoga or meditation.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Use hot or cold packs on your breasts to help alleviate discomfort.
  • Choose a supportive, well-fitting bra, preferably one that has been professionally fitted.
  • Practice relaxation techniques to manage stress and anxiety that may accompany severe breast pain.
  • Limit or avoid caffeine consumption.
  • Eat a low-fat diet and focus on foods rich in complex carbohydrates.
  • Rubbing evening primrose oil on your breasts may help balance fatty acids in the cells and reduce pain.
  • Keep track of when your breast pain occurs and any other symptoms to determine if the pain is regular or not.
  • Vitamin E supplements may help reduce pain for women who experience pain linked to their menstrual cycle.
  • Over-the-counter pain relievers like acetaminophen or ibuprofen can provide relief, but be sure to consult your doctor for the correct dosage, as prolonged use may cause side effects.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.
  • The doctor or healthcare professional will administer Progivian-AQ 50 mg Injection 2.237 ml.
  • Progivian-AQ 50 mg Injection 2.237 ml is intended for use by women only.
  • Do not self-administer.

How Progivian-AQ 50 mg Injection 2.237 ml Works

Progivian-AQ 50 mg Injection 2.237 ml contains progesterone, a naturally occurring female hormone that helps regulate the menstrual cycle and supports pregnancy. Progivian-AQ 50 mg Injection 2.237 ml works by acting on the lining of the uterus (endometrium), changing it from a growing phase to a receptive phase. This prepares the uterus to receive and support a fertilised egg if pregnancy occurs. If pregnancy does not occur, Progivian-AQ 50 mg Injection 2.237 ml helps the uterine lining shed normally, resulting in a regular menstrual period. Progivian-AQ 50 mg Injection 2.237 ml also helps maintain the uterine lining during early pregnancy, creating a suitable environment for the developing embryo and supporting the continuation of pregnancy. Together, these actions help regulate the menstrual cycle, prepare the uterus for pregnancy, and support early pregnancy when required.
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Alcohol

Consult your doctor

It is not known if alcohol affects Progivian-AQ 50 mg Injection 2.237 ml. In case of any concerns, discuss them with the doctor. However, it is advisable not to take or limit alcohol as a precautionary measure.

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Pregnancy

Consult your doctor

Progivian-AQ 50 mg Injection 2.237 ml is used in pregnancy conditions like threatened abortion, luteal phase support, and maintenance of pregnancy. Your doctor will weigh the benefits to outweigh the risks before prescribing this medicine.

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Breast Feeding

Consult your doctor

Let your doctor know if you are a nursing mother before receiving Progivian-AQ 50 mg Injection 2.237 ml; your doctor will decide whether Progivian-AQ 50 mg Injection 2.237 ml can be taken by breastfeeding mothers or not.

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Driving

Unsafe

Avoid driving or operating machinery if you experience drowsiness after receiving this injection.

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Liver

Consult your doctor

Inform your doctor before receiving the Progivian-AQ 50 mg Injection 2.237 ml if you have a history of or ongoing liver disease.

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Kidney

Consult your doctor

Inform your doctor before receiving the Progivian-AQ 50 mg Injection 2.237 ml if you have renal insufficiency or kidney problems. This medicine is excreted through urine, and if you have kidney problems, it may worsen your condition. Your doctor will adjust the dose of this medicine if required based on your condition.

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Children

Unsafe

Progivian-AQ 50 mg Injection 2.237 ml is not recommended for use in children.

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Heart

Caution

Progivian-AQ 50 mg Injection 2.237 ml should be used with caution in people with heart conditions, as it may increase the risk of heart attack, stroke, or blood clots when combined with estrogen therapy. Always consult your doctor to evaluate the risks and determine if it's safe for your specific cardiac profile.

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Geriatrics

Caution

Geriatric patients can receive Progivian-AQ 50 mg Injection 2.237 ml, but it may be more sensitive to side effects like blood clots, fluid retention, or changes in mood. It's important to use it under close medical supervision with individualized dosing.

What if I have taken an overdose of Progivian-AQ 50 mg Injection 2.237 ml

In case of an accidental overdose or if you suspect you have received too much of this medication, seek immediate emergency medical attention or contact a poison control centre. Symptoms of an overdose may include severe dizziness, nausea, or sleepiness.

Diet & Lifestyle Advise

  • Focus on bone health: Since hormone levels can affect bone density, ensure your diet includes adequate calcium and vitamin D through foods like leafy greens, dairy or fortified plant milks, and fish.
  • Stay hydrated: Drink plenty of water daily to help manage mild fluid retention and bloating that can occur with hormone therapy.
  • Eat balanced meals: Focus on whole foods, including lean proteins, healthy fats (like avocados and nuts), and complex carbohydrates to support overall metabolic and hormonal health.
  • Incorporate gentle exercise: Engage in regular, low-impact physical activities like walking, swimming, or yoga to help manage stress, improve circulation, and reduce the risk of blood clots.
  • Manage stress: Practice relaxation techniques such as deep breathing, meditation, or light stretching, as high stress levels can further disrupt your body's natural hormone levels.
health query

Have a query?

How Soon It Starts Working

The time required for Progivian-AQ 50 mg Injection 2.237 ml to start to work: The onset time of Progivian-AQ 50 mg Injection 2.237 ml has not been clinically established. 

The time for which the effects of Progivian-AQ 50 mg Injection 2.237 ml last: The duration of Progivian-AQ 50 mg Injection 2.237 ml’s effect is clinically not established.

What if you forget to take Progivian-AQ 50 mg Injection 2.237 ml

If you miss a dose, contact your doctor or pharmacist immediately for instructions. Do not double the dose to make up for a missed one, as this can disrupt your hormonal balance.

Storage

• Store Progivian-AQ 50 mg Injection 2.237 ml vials or pre-filled syringes at controlled room temperature, ideally between 20°C to 25°C (68°F to 77°F).

Drug Warnings

  • Inspect the solution: Always look closely at the vial before drawing up your dose; the liquid should be clear or pale yellow and free of any floating particles.
  • Rotate injection sites: Never inject into the exact same spot twice in a row; keeping a simple log of where you inject can help prevent painful skin lumps or tissue damage.
  • Practise strict needle safety: Use a sterile needle and syringe for every single injection, and never share injection equipment with anyone else to avoid serious infections.
  • Watch for signs of blood clots: Be vigilant for sudden leg pain, warmth, redness, or unexplained shortness of breath, as hormone injections can slightly increase the risk of blood clots.
  • Avoid heavy machinery: If this injection makes you feel drowsy, dizzy, or lightheaded, avoid driving or operating tools until you know how the medicine affects you.

Drug-Drug Interactions

verifiedApollotooltip

The following medicines may interact with Progivian-AQ 50 mg Injection 2.237 ml:

  •  Liver enzyme inducers (such as rifampin or carbamazepine): May speed up how your body processes this medicine, which can lower its effectiveness.
  • Ketoconazole: May slow down the breakdown of this medication in your liver, potentially raising its levels in your body and increasing the risk of side effects.
ProgesteroneVenetoclax
Severe
ProgesteroneEdoxaban
Severe

Drug-Drug Interactions

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ProgesteroneVenetoclax
Severe
How does the drug interact with Progivian-aq 50mg Inj 2.237ml:
Co-administration of Progivian-aq 50mg Inj 2.237ml with Venetoclax may increase the blood levels of Venetoclax which increases the risk of side effects.

How to manage the interaction:
Although taking Progivian-aq 50mg Inj 2.237ml and Venetoclax together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any symptoms such as fatigue, nausea, vomiting, diarrhea, and infections, it is advised to consult a doctor. Without consulting a doctor, never stop taking any drugs.
ProgesteroneEdoxaban
Severe
How does the drug interact with Progivian-aq 50mg Inj 2.237ml:
When Progivian-aq 50mg Inj 2.237ml is taken with Edoxaban, may increase the blood levels of Edoxaban which increases the risk of serious bleeding complications.

How to manage the interaction:
Although taking Progivian-aq 50mg Inj 2.237ml and edoxaban together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that resembles coffee grounds, severe headache, and weakness, you should consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Progivian-aq 50mg Inj 2.237ml:
Co-administration of Progivian-aq 50mg Inj 2.237ml with Morphine may increase the blood levels and side effects of Morphine.

How to manage the interaction:
Co-administration of Morphine with Progivian-aq 50mg Inj 2.237ml can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms like trouble breathing, feeling tired, or having a cough, dizziness, drowsiness, difficulty concentrating, impaired judgment, reaction speed, and motor coordination, make sure to contact a doctor immediately. Do not stop using any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip

The following food-related information should be considered while using Progivian-AQ 50 mg Injection 2.237 ml:

  • There are no specific food interactions established with this injectable medication, but maintaining a balanced diet supports your overall hormonal health.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[HORMONES]

FAQs

Progivian-AQ 50 mg Injection 2.237 ml is used to treat various medical conditions, including early pregnancy maintenance, dysfunctional uterine bleeding, and threatened abortion. Besides this, it can also be used for the progesterone withdrawal test in the endocrinal evaluation of secondary amenorrhoea (paused or missed periods) to judge oestrogen priming.
Progivian-AQ 50 mg Injection 2.237 ml contains progesterone; it works by increasing levels of the hormone progesterone in your body.
The most prevalent negative effect of using Progivian-AQ 50 mg Injection 2.237 ml is the darkening of the facial skin. Please report to the doctor immediately if you notice any significant or rapid changes.
Using Progivian-AQ 50 mg Injection 2.237 ml is contraindicated in people with cancers such as breast or genital organs. So, inform your doctor if you have cancer in your breasts or genital organs.
Progivian-AQ 50 mg Injection 2.237 ml is contraindicated in people allergic to progesterone or people diagnosed with porphyria (a disorder in the formation of red blood pigment), cancers in breasts or genital organs, or a blocked blood vessel, vaginal infections, and/or people with missed abortion.
Hair loss is the most prevalent negative effect of utilizing Progivian-AQ 50 mg Injection 2.237 ml. If you notice any significant or abnormal hair loss, please immediately report it to the doctor.
Yes, you can inject Progivian-AQ 50 mg Injection 2.237 ml at home, but only after receiving thorough training from your healthcare provider. Your doctor or nurse will teach you how to prepare the dose, inject it safely, and dispose of the needles properly. If you ever feel unsure about the process, talk to your doctor or pharmacist before administering your next dose.
Mild pain, redness, or a small lump at the injection site is common. You can help prevent this by rotating your injection sites daily and applying a warm compress gently to the area after injecting, if your doctor approves. If the pain worsens, or if you notice signs of infection like pus, intense warmth, or spreading redness, talk to your doctor immediately.
No, Progivian-AQ 50 mg Injection 2.237 ml is not a contraceptive and will not prevent pregnancy. In fact, it is often prescribed to support early pregnancy in women undergoing fertility treatments. If you are not trying to conceive, talk to your doctor about appropriate and safe birth control options while using this medication.
It is highly recommended to limit or avoid alcohol while using Progivian-AQ 50 mg Injection 2.237 ml. Alcohol can worsen side effects like dizziness and drowsiness, and it can also interfere with your liver's ability to process the medication. Talk to your doctor or pharmacist if you have questions about alcohol use.
Some women experience mild weight changes or bloating while taking Progivian-AQ 50 mg Injection 2.237 ml, which is often due to temporary fluid retention rather than an increase in body fat. If you notice rapid weight gain, severe swelling in your hands or feet, or if the weight gain concerns you, talk to your doctor.
This medicine can pass into breast milk, and its effects on a nursing infant are not fully established. Therefore, you should always consult your healthcare provider before using this injection if you are currently breastfeeding or planning to breastfeed. Talk to your doctor to weigh the risks and benefits.
The most important factor is consistency. You should take your Progivian-AQ 50 mg Injection 2.237 ml injection at the exact same time every day to maintain stable hormone levels in your body. Discuss with your doctor or pharmacist to determine the most convenient daily schedule for you.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Office/Unit No.:-605, 6th Floor, Omega Business Park, Ambica Nagar, Wagle Industrial Estate, Thane West, Mumbai, Thane, Maharashtra 400604
Other Info - PRO3800
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