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compositionComposition:PRIMIDONE-100MG
prescription
Prescription Medicine
info
Prolet SR 100 Tablets 15's
Prolet SR 100 Tablets 15's

Prolet SR 100 Tablets is used to control seizures. It contains Primidone which works by decreasing abnormal electrical activity in the brain. In some cases, this medicine may cause side effects such as nausea, headache, vomiting, drowsiness, vertigo, visual impairment, low energy, and impaired coordination. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

PRIMIDONE-100MG

Manufacturer/Marketer :

Alteus Biogenics Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Prolet SR 100 Tablets

Prolet SR 100 Tablets is used to control various epileptic conditions (fits), prevent seizures and treat shaking attacks (essential tremors). Epilepsy is a central nervous system disorder characterized by a sudden rush of electrical activity in the brain, leading to seizures, unusual behaviour, and loss of awareness. Prolet SR 100 Tablets is ineffective for treating absence (petit mal) seizures.

Prolet SR 100 Tablets contains 'Primidone', which increases the activity of a chemical messenger (GABA) that suppresses the brain's excessive and abnormal activity of nerve cells. Our brain cells (neurons) work by firing at a certain rate to function normally. However, during an epileptic attack or seizure, our neurons are forced to work rapidly compared to normal conditions. Prolet SR 100 Tablets prevents neurons from working at a very fast speed, thereby preventing all brain cells from firing together rapidly in an uncontrolled way. As a result, episodes of seizures are stopped at their initial point only. 

Take Prolet SR 100 Tablets with or without food. You are advised to take Prolet SR 100 Tablets for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as nausea, headache, vomiting, drowsiness, vertigo, visual impairment, low energy, impaired coordination, and nystagmus (involuntary eye movement). Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

To treat your condition, effectually continue taking Prolet SR 100 Tablets for as long as your doctor has prescribed it. Please do not skip any doses or stop taking Prolet SR 100 Tablets suddenly without consulting your doctor, as it may lead to increased seizures. Avoid taking Prolet SR 100 Tablets if you are pregnant or breastfeeding unless prescribed. Prolet SR 100 Tablets should not be given to children unless prescribed by a doctor. Avoid alcohol consumption while taking Prolet SR 100 Tablets as it might increase side effects. Inform your doctor about all the medicines you are taking and your health condition to rule out any unpleasant side effects.

Uses of Prolet SR 100 Tablets

Prolet SR 100 Tablets is used to treat Epilepsy (fits), Bipolar disorder, and Migraine. The detailed use of Prolet SR 100 Tablets is as follows:

  • Epilepsy/Seizures: Prolet SR 100 Tablets is used alone or with other medications to control various types of seizures, including focal and generalized tonic-clonic seizures.

Key Benefits

Prolet SR 100 Tablets belongs to the group of anticonvulsant medicines. It contains Primidone, which is used to control epilepsy (fits). Prolet SR 100 Tablets is also used to control and prevent fits during or after a severe head injury or brain surgery. Prolet SR 100 Tablets is also used to treat trigeminal neuralgia (facial nerve pain). Prolet SR 100 Tablets works by controlling the overactivity of the brain that causes seizures (fits). Thereby, Prolet SR 100 Tablets helps in controlling epileptic fits involving muscle spasms and jerking.

Side effects of Prolet SR 100 Tablets
  • Regular eye exams can detect conditions causing Involuntary Eye Movement.
  • Alcohol and drugs should be avoided as they can increase the symptoms of nystagmus.
  • Wearing corrective lenses for refractive errors can reduce eye strain and symptoms.
  • Stress management and getting proper sleep can help to reduce symptoms.
  • Get enough sleep. Maintain a regular sleep cycle.
  • Eat a healthy diet and exercise regularly.
  • Manage stress with yoga or meditation.
  • Limit alcohol and caffeine.
  • Avoid driving or operating machinery unless you are alert.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Uncoordinated muscle movements need immediate medical attention.
  • Observe your movements and try to understand and control the particular movement.
  • Regularly do strengthening exercises to improve blood flow throughout the body and avoid involuntary movements.
  • Implement massage techniques to enhance blood flow to organs.
  • Take a balanced diet and quit smoking.
  • Practice yoga and meditation to improve thought processes and reduce uncontrolled and involuntary movements.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Directions for Use

  • Prolet SR 100 Tablets can be taken with or without food, as advised by your doctor.
  • It is usually taken twice daily or as prescribed by your doctor.
  • Swallow Prolet SR 100 Tablets as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Prolet SR 100 Tablets Works

Prolet SR 100 Tablets contains 'Primidone', which increases the activity of a chemical messenger (GABA) that suppresses the brain's excessive and abnormal activity of nerve cells. Our brain cells (neurons) work by firing at a certain rate to function normally. However, during an epileptic attack or seizure, our neurons are forced to work rapidly compared to normal conditions. Prolet SR 100 Tablets prevents neurons from working at a very fast speed, thereby preventing all brain cells from firing together rapidly in an uncontrolled way. As a result, episodes of seizures are stopped at their initial point only.
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Alcohol

Caution

You are recommended to avoid alcohol consumption while taking Prolet SR 100 Tablets to prevent unpleasant side effects.

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Pregnancy

Caution

Do not take Prolet SR 100 Tablets if you are pregnant unless prescribed by the doctor. If you become pregnant while taking Prolet SR 100 Tablets , then do not stop taking Prolet SR 100 Tablets without consulting your doctor. Your doctor will prescribe Prolet SR 100 Tablets only if the benefits outweigh the risks.

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Breast Feeding

Caution

Please consult your doctor if you have any concerns regarding this; your doctor will decide whether Prolet SR 100 Tablets can be given to breastfeeding mothers.

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Driving

Caution

Prolet SR 100 Tablets may cause dizziness and drowsiness, drive and operate machinery only if you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have liver problems or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Prolet SR 100 Tablets can be given to children if prescribed by the doctor.

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Heart

Caution

Prolet SR 100 Tablets should be taken with caution in patients with heart problems. Please inform your doctor if you have any pre-existing heart problems before using Prolet SR 100 Tablets .

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Geriatrics

Caution

Prolet SR 100 Tablets can be given in elderly patients with extreme caution, if prescribed by the physician. Careful monitoring of the patient is required.

What if I have taken an overdose of Prolet SR 100 Tablets

Take Prolet SR 100 Tablets only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Overdose of Prolet SR 100 Tablets may cause ataxia (loss of muscle control), loss of consciousness, respiratory depression and coma. Seek immediate medical attention if you have taken an overdose.

Diet & Lifestyle Advise

  • Following a ketogenic diet (low in carbohydrates and high in fat) is recommended.
  • Meditation, walking, participating in a task, and smelling a strong odour are a few self-control methods for preventing seizures.
  • Acupuncture therapy may also be helpful.
  • Rest properly. Avoid stress by doing meditation or yoga.

Have a query?

How Soon It Starts Working

The time required for Prolet SR 100 Tablets to start to work: Prolet SR 100 Tablets ideally shows its action within 3 hours after administration. The time for which the effects of Prolet SR 100 Tablets last: The duration of action for Prolet SR 100 Tablets is clinically unknown.

What if you forget to take Prolet SR 100 Tablets

Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and follow your regular dosing schedule. Do not take a double dose to make up for your missed dose.

Storage

• Store in a cool and dry place away from sunlight. • Keep Prolet SR 100 Tablets out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

Do not take Prolet SR 100 Tablets if you are allergic to any of its contents. Do not skip doses or stop taking Prolet SR 100 Tablets suddenly without consulting your doctor, as Prolet SR 100 Tablets may cause increased seizures. Talk to your doctor if you have heart, kidney, or liver problems. Avoid taking Prolet SR 100 Tablets if you are pregnant or breastfeeding unless prescribed by your doctor. Avoid alcohol consumption while taking Prolet SR 100 Tablets as it might cause unpleasant side effects. Prolet SR 100 Tablets should not be used by children unless prescribed. Let your doctor know if you have diabetes, as intake of Prolet SR 100 Tablets affects the blood sugar level. Intake of Prolet SR 100 Tablets may cause dizziness, so be cautious while driving or operating heavy machinery.

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interaction: Prolet SR 100 Tablets may have interaction with a blood thinner (fluindione, phenindione, warfarin), other medicines used to treat epilepsy (phenytoin, felbamate, valproic acid, carbamazepine, lamotrigine), immunosuppressants (cyclosporine, tacrolimus, sirolimus, everolimus), steroids (dexamethasone, prednisone), antidepressants (lurasidone, lamotrigine), anti-cancer (cyclophosphamide), antimalaria (quinine), HIV medicines (boceprevir, cobicistat, lopinavir), asthma medicines (theophylline, montelukast).

Drug-Food Interaction: Prolet SR 100 Tablets is known to interact with St. John's wort (an antidepressant herbal supplement).

Drug-Disease Interaction: Prolet SR 100 Tablets may have interactions with heart problems, diabetes, asthma, alcoholism, porphyria (a rare inherited disorder of metabolism), blood disorders, and kidney or liver problems.

PrimidonePirfenidone
Critical
PrimidoneBoceprevir
Critical

Drug-Drug Interactions

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PrimidonePirfenidone
Critical
How does the drug interact with Prolet SR 100 Tablets:
Coadministration of pirfenidone with Prolet SR 100 Tablets can reduce levels and the effects of pirfenidone.

How to manage the interaction:
Although there is an interaction between pirfenidone and Prolet SR 100 Tablets, they can be taken together if advised by your doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
PrimidoneBoceprevir
Critical
How does the drug interact with Prolet SR 100 Tablets:
Coadministration of boceprevir with Prolet SR 100 Tablets may decrease the blood levels of boceprevir, which may make it less effective in treating the condition.

How to manage the interaction:
Although there is an interaction between Prolet SR 100 Tablets and boceprevir, they can be taken together if your doctor advises. However, contact your doctor if you experience any symptoms. Do not stop taking any medications without consulting a doctor.
PrimidoneRanolazine
Critical
How does the drug interact with Prolet SR 100 Tablets:
Coadministration of ranolazine with Prolet SR 100 Tablets can reduce the blood levels and effects of ranolazine.

How to manage the interaction:
Although there is an interaction between Prolet SR 100 Tablets and Ranolazine, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
PrimidoneRitonavir
Critical
How does the drug interact with Prolet SR 100 Tablets:
Taking ritonavir and Prolet SR 100 Tablets may decrease the blood levels of ritonavir.

How to manage the interaction:
Taking Prolet SR 100 Tablets with Ritonavir is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
PrimidonePraziquantel
Critical
How does the drug interact with Prolet SR 100 Tablets:
Taking praziquantel with Prolet SR 100 Tablets can lower the levels of praziquantel in your blood, which leads to a decreased therapeutic effect.

How to manage the interaction:
Taking Prolet SR 100 Tablets with Praziquantel is not recommended. Please consult your doctor before taking it. They can be taken together if advised by your doctor. However, contact your doctor if you experience any symptoms. Do not stop taking any medications without consulting a doctor.
PrimidoneDaclatasvir
Critical
How does the drug interact with Prolet SR 100 Tablets:
Coadministration of daclatasvir with Prolet SR 100 Tablets may decrease the blood levels of daclatasvir, which may make the medication less effective in treating the condition.

How to manage the interaction:
Although there is an interaction between Prolet SR 100 Tablets and Daclatasvir, they can be taken together if advised by your doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
PrimidoneVoriconazole
Critical
How does the drug interact with Prolet SR 100 Tablets:
Taking voriconazole together with Prolet SR 100 Tablets may reduce the blood levels of voriconazole, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between Voriconazole and Prolet SR 100 Tablets, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
PrimidoneIsavuconazole
Critical
How does the drug interact with Prolet SR 100 Tablets:
Taking isavuconazole with Prolet SR 100 Tablets may decrease the blood levels of isavuconazole and reduce its effectiveness.

How to manage the interaction:
Taking isavuconazole with Prolet SR 100 Tablets is not recommended, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
PrimidoneLurasidone
Critical
How does the drug interact with Prolet SR 100 Tablets:
Co-administration of lurasidone with Prolet SR 100 Tablets may result in significantly lower blood levels of lurasidone, making the medication less effective or ineffective in treating your illness.

How to manage the interaction:
There is an interaction between Lurasidone and Prolet SR 100 Tablets, so it is not recommended; it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
PrimidoneImatinib
Severe
How does the drug interact with Prolet SR 100 Tablets:
Coadministration of imatinib with Prolet SR 100 Tablets may decrease the blood levels of the and reduce its effectiveness.

How to manage the interaction:
Although there is an interaction between Imatinib and Prolet SR 100 Tablets, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTICONVULSANT]

FAQs

Prolet SR 100 Tablets is used for the treatment of Epilepsy (fits), Bipolar disorder, and Migraine.
Prolet SR 100 Tablets works by controlling overactivity of the brain that causes seizures (fits). Thereby, Prolet SR 100 Tablets helps in controlling epileptic fits involving spasms of the muscles and jerking.
Prolet SR 100 Tablets can make birth control pills less effective. Talk to your doctor about using non-hormonal contraceptives like condoms and diaphragm with spermicide to prevent pregnancy.
Please do not stop taking Prolet SR 100 Tablets without consulting your doctor as it may cause increased seizures. Continue taking Prolet SR 100 Tablets for as long as your doctor prescribes it. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Prolet SR 100 Tablets .
Yes, Prolet SR 100 Tablets may cause swelling in the gums. Brush and floss your teeth daily; visit your dentist if you experience this problem regularly.
You should not take Prolet SR 100 Tablets if you have liver disease, kidney disease, porphyria (an inherited disease that affects haemoglobin biosynthesis), alcohol dependence and suicidal thoughts.
Primidone may affect the breakdown of blood sugar/glucose and may prevent the release of insulin, thereby leading to high blood sugar. This is important if you have diabetes. So, contact a doctor before using Prolet SR 100 Tablets in this condition.
A partial seizure, also known as a focal seizure, occurs when there is abnormal electrical activity in just one part of the brain. These seizures can cause a variety of symptoms depending on the area of the brain affected.
It is essential to inform your doctor if are allergic to Prolet SR 100 Tablets , if you are taking vitamins, supplements, herbal products and other medicines. Let your know doctor if you have or have ever had porphyria (condition in which certain natural substances accumulate in the body and may cause changes in thinking and behaviour, stomach pain, or other symptoms). It is crucial to inform your doctor if you are pregnant or planning to become pregnant.
No, Prolet SR 100 Tablets is not habit forming. However, with the long-term use, Prolet SR 100 Tablets can be habit forming. So it's important to take it exactly as prescribed by your doctor. If you have any concerns regarding this, please discuss with your doctor.
If Prolet SR 100 Tablets makes you feel sleepy, avoid driving or operating heavy machinery. Avoid taking Prolet SR 100 Tablets if you are pregnant or breastfeeding unless prescribed by your doctor. Avoid alcohol consumption while taking Prolet SR 100 Tablets as it may cause unpleasant side effects.
The serious side effects of Prolet SR 100 Tablets are painful joints, yellowing of the skin and/or eyes, fever, bleeding or bruising under the skin, suicidal thoughts or behaviour, unusual changes in moods, worsening of depression and swelling of the face, lips, tongue or throat. To check for these side effects, it's important to, monitor for symptoms, and inform your doctor immediately if you notice any of these symptoms.
Yes, Prolet SR 100 Tablets can cause headache as a mild and temporary side effect. However, if you experience persistent or severe headaches, please consult your doctor.
No, Prolet SR 100 Tablets does not have any effect on blood pressure. However consult your doctor, if you notice any changes in the blood pressure.
You are recommended to consult your doctor before taking Prolet SR 100 Tablets with propranolol or any other medicines to avoid possible interactions.
Store Prolet SR 100 Tablets at room temperature in a cool and dry place away from sunlight. Keep it out of reach of children.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Alteus Biogenics Pvt. Ltd., 14-B Dover Lane, Kolkata - 700029, WB, India.
Other Info - PRO2453

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