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Protomid Tablet is used to treat tuberculosis (TB). It contains Prothionamide which works by preventing the bacteria from multiplying and kills them. In some cases, this medicine may cause side effects such as metallic taste, dry mouth, loss of appetite, and nausea. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions. You can take it with food to reduce side effects on the gut.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

PROTHIONAMIDE-250MG

Manufacturer/Marketer :

Macleods Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Protomid Tablet

Protomid Tablet is a prescription medicine used to treat tuberculosis (TB), a serious bacterial infection that primarily affects the lungs. It is typically prescribed as part of a combination therapy with other medicines to ensure the infection is completely cleared. This medicine is especially important for treating infections that have become resistant to standard first-line therapies.

To get the best results, you must take Protomid Tablet consistently every single day exactly as your healthcare provider instructs. You can take this medicine with or after meals to help prevent an upset stomach. Eating a highly nutritious, protein-rich diet can also help your body heal and regain strength during your treatment.

While taking Protomid Tablet , you may experience some mild side effects such as nausea, a metallic taste in your mouth, or a loss of appetite. However, you should contact your doctor immediately if you notice serious signs like yellowing of your skin or eyes, dark urine, severe stomach pain, or persistent tingling in your hands and feet.

Before starting this medication, tell your doctor if you have a history of liver disease, kidney problems, diabetes, or mental health conditions like depression. Do not take this if you have severe liver damage, as this medication can place extra strain on your liver.

This medicine can interact with alcohol, which significantly increases your risk of liver damage and severe dizziness, so you should avoid drinking alcohol during treatment. If you are pregnant, planning to become pregnant, breastfeeding, or are an elderly individual, consult your doctor or pharmacist before taking Protomid Tablet to ensure it is safe for you.

Uses of Protomid Tablet

Protomid Tablet is used to treat tuberculosis (TB). The detailed uses of Protomid Tablet are as follows:

  • Tuberculosis (TB): Protomid Tablet is used alongside other medicines to treat active tuberculosis infections, especially cases that are resistant to standard treatments. It helps by stopping the growth of the bacteria responsible for the disease.

Key Benefits

Protomid Tablet helps treat tuberculosis by eliminating the bacteria responsible for the infection, allowing your body to recover and preventing the disease from spreading. With regular use as prescribed, it relieves symptoms, promotes healing, and supports long-term recovery.

  • Treats Tuberculosis Infection: By targeting and eliminating the bacteria that cause tuberculosis, this medicine helps clear the infection and supports healing of the lungs and other affected organs.
  • Relieves Tuberculosis Symptoms: As the infection improves, this medicine helps reduce symptoms such as a persistent cough, fever, night sweats, and unexplained weight loss, allowing you to gradually regain your strength and energy.
  • Helps Prevent the Spread of Tuberculosis: Completing the full course of treatment helps prevent the infection from spreading to others while reducing the risk of treatment failure and recurrence.
Side effects of Protomid Tablet
  • Frequent flossing and brushing can help remove bacteria and debris that can give your teeth a metallic taste.
  • The metallic flavor may be caused by a zinc deficiency. Eat foods like meat, chicken, and oysters that are high in zinc.
  • Reducing the intake of foods with strong aromas, like onions and garlic, as they may intensify the taste of metallic substances.
  • Avoid smoking and tobacco products as they may intensify the metallic flavor.
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Directions for Use

  • Protomid Tablet should be taken after meals to avoid stomach upset.
  • It is usually taken once daily or as prescribed by your doctor.
  • Swallow Protomid Tablet as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Protomid Tablet Works

Protomid Tablet contains prothionamide, which works by directly targeting the specific bacteria that cause tuberculosis. It interferes with the chemical processes the bacteria use to build their protective outer cell walls. Without these strong outer walls, the bacteria cannot survive, grow, or multiply in your body. As the bacteria are weakened and prevented from multiplying, your body's natural immune system is better able to identify and destroy them. Because tuberculosis bacteria can be highly resilient, this medicine is designed to work in combination with other antibacterial drugs to ensure all the bacteria are thoroughly eliminated and do not develop resistance.
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Alcohol

Caution

Consuming alcohol along with Protomid Tablet is not advisable as it may cause unpleasant side effects.

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Pregnancy

Caution

Please consult the doctor. There are no adequate and well-controlled studies on pregnant women. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Please consult the doctor. There are no adequate and well-controlled studies on pregnant women. Your doctor will prescribe only if the benefits outweigh the risks.

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Driving

Caution

Patients who experience dizziness or lightheadedness while receiving Protomid Tablet should refrain from operating machinery.

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Liver

Caution

There is limited information available on the use of Protomid Tablet in patients with liver disease. Your doctor will weigh the benefits and any potential risks before prescribing them to you. Please consult your doctor.

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Kidney

Caution

There is limited information available on the use of Protomid Tablet in patients with Kidney disease. Your doctor will weigh the benefits and any potential risks before prescribing them to you. Please consult your doctor.

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Children

Caution

Protomid Tablet is not recommended for children below 18 years of age.

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Heart

Caution

Protomid Tablet should be taken with caution in patients with heart problems. Therefore, please inform your doctor before using Protomid Tablet .

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Geriatrics

Caution

Protomid Tablet should be given with caution in elderly patients due to an increased risk of side effects. Please consult your doctor before using Protomid Tablet .

What if I have taken an overdose of Protomid Tablet

If you suspect an overdose or have taken more than the prescribed amount, seek immediate emergency medical attention.

Diet & Lifestyle Advise

  • Eat a nutrient-rich diet: Tuberculosis can cause significant weight loss and muscle wasting. Focus on eating high-calorie, protein-rich foods like lean meats, beans, eggs, and dairy to help your body rebuild and recover.
  • Avoid alcohol completely: Since Protomid Tablet is processed by the liver, drinking alcohol highly increases your risk of developing severe liver damage.
  • Ask about Vitamin B6: Talk to your doctor about taking a Vitamin B6 (pyridoxine) supplement, as this can help prevent nerve tingling or numbness in your limbs during treatment.
  • Stay well-hydrated: Drink plenty of water throughout the day to support your kidneys and overall metabolic function.
  • Get plenty of rest: Your body requires extra energy to fight a tuberculosis infection. Ensure you get adequate sleep and avoid overexertion.
health query

Have a query?

How Soon It Starts Working

The time required for Protomid Tablet to start to work: The exact onset time of Protomid Tablet has not been clinically established. The time for which the effects of Protomid Tablet last: The duration of Protomid Tablet ’s effect is clinically not established.

What if you forget to take Protomid Tablet

If you miss a dose, take it as soon as you remember. However, if it is nearly time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store Protomid Tablet tablets in their original packaging at room temperature, ideally between 15°C and 30°C (59°F to 86°F). •Keep the container tightly closed to protect the medicine from moisture and direct light.

Drug Warnings

  • Attend all laboratory appointments: You will need regular blood tests while taking Protomid Tablet so your doctor can monitor your liver function and ensure it is safe to continue treatment.
  • Finish the entire prescription: Never stop taking this medicine early, even if your symptoms improve. Stopping early can cause the tuberculosis bacteria to return and become resistant to treatments.
  • Check your tablets before use: Inspect your tablets before taking them; do not use them if they are discoloured, crumbled, or show signs of moisture damage.
  • Monitor your mental health: Alert a family member or friend that you are taking this medicine, as it can occasionally cause sudden mood shifts or depression.
  • Be cautious when driving: This medication can cause dizziness or drowsiness. Avoid driving or operating heavy machinery until you know how it affects you.

Drug-Drug Interactions

verifiedApollotooltip
  • Other tuberculosis medications: Taking this alongside certain other TB drugs (like isoniazid or rifampicin) may increase the risk of liver damage.
  • Seizure medications: It may alter the levels of certain anti-seizure drugs in your blood, requiring dose adjustments.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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  • Alcohol: Consuming alcohol while on this medication significantly increases the risk of severe liver damage and central nervous system side effects like dizziness.
     
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTI- TUBERCULOSIS]

FAQs

Protomid Tablet is used to treat Tuberculosis (TB).
Protomid Tablet consists of medicine called Prothionamide. Prothionamide is clinically effective in treating TB; the precise mechanisms of action remain unknown, but a cell-based activation method causes an inhibiting complex.
No, please do not stop taking Protomid Tablet even if you feel better as it may worsen your condition. For the best advice, consult your doctor and do as recommended.
No, it is a prescribed drug given by a physician for preventing specific medical conditions. Taking it on your own can cause unwanted side effects.
You can take Protomid Tablet with or without food. However, if you find that it upsets your stomach or causes nausea, taking it with or immediately after a meal can help reduce these side effects. Talk to your doctor or pharmacist for personalised advice.
Yes, this medicine can sometimes affect your nerves, leading to numbness, tingling, or a burning sensation in your hands and feet. Your doctor may prescribe a Vitamin B6 supplement to help prevent this. If you experience these symptoms, talk to your doctor.
No, you should avoid alcohol completely while taking Protomid Tablet . Both alcohol and this medicine place stress on your liver, and combining them significantly increases your risk of serious liver damage. Talk to your doctor if you find this difficult.
Yes, Protomid Tablet has the potential to cause liver damage. Your healthcare provider will schedule regular blood tests to monitor your liver function throughout your treatment. If you notice yellowing of your eyes or skin, dark urine, or severe stomach pain, seek medical help immediately. Talk to your doctor.
Nausea is a common side effect of this medicine. Try taking your dose with food or ask your doctor about splitting doses. If the nausea is severe, prevents you from keeping food down, or does not improve, talk to your doctor or pharmacist.
Protomid Tablet is generally only prescribed during pregnancy if the potential benefits outweigh the risks to the unborn baby. If you are pregnant or planning to become pregnant, talk to your doctor to weigh your treatment options safely.
Yes, it is often used alongside other TB medications, but some combinations can increase the risk of side effects like liver damage. Your doctor will carefully select your combination of medicines to ensure they are safe to use together. Talk to your doctor.

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Country of origin

India

Manufacturer/Marketer address

Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.
Other Info - PRO0095
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