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Recommendations for treating extra-pulmonary MDR TB affecting the spinal cord?
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Recommendations for treating extra-pulmonary MDR TB affecting the spinal cord?
Asked by Male, 58 · 2 months ago
Spinal MDR-TB is treated with strong TB medicines chosen by specialists, usually for many months. Doctors track progress with scans and checkups. Surgery is needed only if the infection is pressing on the spinal cord or causing weakness or deformity.
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How long is the treatment for spinal MDR TB?What drugs are used for MDR TB in the spine?Are surgery options needed for spinal MDR TB?How is treatment response monitored?What are common side effects of MDR TB drugs?
Overview of Extra-Pulmonary MDR TB Affecting the Spinal Cord
- Multidrug-resistant tuberculosis (MDR TB) can affect the spinal cord, leading to spinal tuberculosis or Pott's disease.
Diagnostic Evaluation
- Confirm diagnosis with imaging (MRI, CT scan) and microbiological tests (culture, GeneXpert MTB/RIF).
Medical Treatment Recommendations
- Use second-line anti-tubercular drugs like linezolid, bedaquiline, and fluoroquinolones.
- Treatment duration is typically 18-24 months.
Monitoring and Supportive Care
- Regular monitoring for treatment response and management of drug side effects.
Role of Surgery
- Consider surgery for spinal instability, neurological deficits, or abscess drainage.
Multidisciplinary Approach
- Involve infectious disease specialists, neurologists, and orthopedic surgeons.
Patient Counseling and Follow-up
- Emphasize adherence to therapy and provide nutritional support.
India-Approved Medications
- Commonly used drugs include linezolid (Zyvox) and bedaquiline (Sirturo).
Answered 2 months ago