Are there any possible side-effects of Proxym-XT Tablet ?

The common side-effects of Proxym-XT Tablet are nausea, vomiting, stomach pain, indigestion, diarrhea, constipation, dizziness, headache, tiredness, rash, ringing in your ears, and increased heartbeat. These side-effects are usually mild and temporary. However, if any of these side-effects persist or get worse, inform your doctor immediately.

Can I take Proxym-XT Tablet with aspirin?

Proxym-XT Tablet should not be taken with aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen, naproxen, and aceclofenac. It may increase the risk of gastrointestinal (stomach and intestine) side-effects. In addition, do not take any over-the-counter (OTC) medicines without consulting a doctor as most of the OTC cold or pain medicines contain an NSAID.

Is Proxym-XT Tablet safe for hypertensive patients?

Proxym-XT Tablet is usually well-tolerated in most of the patients. However, it should be used with caution in patients with high blood pressure and high cholesterol as it increases the risk of a heart attack in higher doses. So, inform your doctor about all the illnesses you have before taking this medicine.

Does Proxym-XT Tablet have any effect on stools?

Proxym-XT Tablet may cause a change in consistency and color of the stools. You may notice clay or black-colored stool while using this medicine. Consult a doctor if the condition persists.

Does Proxym-XT Tablet cause liver damage?

Proxym-XT Tablet contains Etodolac and Paracetamol, which may cause liver damage when used in higher doses or longer durations. So, take this medicine for a dose and duration as intended by your doctor. Also, avoid alcohol intake while using this medicine, as alcohol may increase the risk of liver damage and stomach bleeding.

What are the instructions for storage of Proxym-XT Tablet ?

Proxym-XT Tablet should be stored in a cool and dry place away from sunlight. Keep it out of sight and reach of children.

Will Proxym-XT Tablet be more effective if taken in higher doses?

No, taking Proxym-XT Tablet higher than the recommended dose will not be effective, rather it may cause unpleasant side effects. Therefore, always take Proxym-XT Tablet in the dose prescribed by the doctor to prevent adverse effects.

Can Proxym-XT Tablet be stopped when my pain is relieved?

No, you should not stop taking Proxym-XT Tablet without consulting the doctor, even if your pain is relieved. Stopping the medication abruptly could lead to a recurrence of pain or other complications. Always follow the doctor’s advice regarding the duration of treatment.

Can the use of Proxym-XT Tablet cause dizziness?

Yes, Proxym-XT Tablet may cause dizziness as a common side effect. If you experience dizziness while using Proxym-XT Tablet , avoid driving and operating heavy machinery unless you are fully alert.

Are there any specific contraindications associated with the use of Proxym-XT Tablet ?

You should not take Proxym-XT Tablet if you are allergic to any of its ingredients. It should not be used by patients with stomach or intestinal ulcers, those who have had an allergic reaction to NSAIDs, or individuals with severe liver, kidney, or heart failure, as well as those with alcoholic liver disease.

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Written By Santoshini Reddy G , M Pharmacy

Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Proxym-XT Tablet is used to treat pain associated with conditions such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. It contains Etodolac and Paracetamol which work by blocking the production of chemical substances that cause pain and swelling. In some cases, this medicine may cause side effects such as nausea, vomiting, stomach pain, indigestion, diarrhoea, constipation, dizziness, and headache. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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About Proxym-XT Tablet

Proxym-XT Tablet is used to treat pain associated with chronic (long-term) conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, etc. Osteoarthritis is a degenerative bone disease in which the tissue supporting the joints wears down. Rheumatoid arthritis is a condition in which the immune system attacks its own tissue, leading to joint pain and inflammation. Ankylosing spondylitis is the inflammation of the spine and large joints.

Proxym-XT Tablet contains Etodolac and Paracetamol. Etodolac is a non-steroidal anti-inflammatory drug (NSAID), and Paracetamol is an analgesic. They act by blocking the production of chemical substances called prostaglandins that cause pain, swelling, and inflammation. The inhibition of these substances can cause a decrease in symptoms such as pain, joint stiffness, and tenderness.

You should take this medicine exactly as prescribed by the doctor. The common side-effects of Proxym-XT Tablet are nausea, vomiting, stomach pain, indigestion, diarrhoea, constipation, dizziness, headache, tiredness, rash, ringing in your ears, clay or black-coloured stools, and increased heartbeat. These side effects are usually mild and temporary. However, if any of these side effects persist or get worse, inform your doctor immediately.

It is not recommended to take Proxym-XT Tablet if you are allergic to any contents of it. Proxym-XT Tablet should not be used in patients with a history of ulcers in the stomach or intestine, who have had an allergic reaction to NSAIDs, have severe liver, kidney, heart failure, and alcoholic liver disease. It is not recommended for use in children, pregnant women, and breastfeeding mothers. It should be used with caution in elderly patients. It is not advised to consume alcohol as it may increase the risk of stomach bleeding. Proxym-XT Tablet may cause dizziness, so do not drive or operate heavy machinery if you are not fully alert.

Uses of Proxym-XT Tablet

Treatment of Pain associated with Osteoarthritis, Rheumatoid arthritis, and Ankylosing spondylitis, etc.

Directions for Use

• Take Proxym-XT Tablet with food to prevent stomach upset or as advised by your doctor.• Follow your doctor's instructions on the dosage and timing of this medication.• Swallow it as a whole with a glass of water.• Do not crush, chew or break it.

Medicinal Benefits

Proxym-XT Tablet is used in the treatment of pain, swelling, and inflammation associated with chronic (long-term) conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, etc. It contains Etodolac and Paracetamol. It acts by blocking the production of chemical substances called prostaglandins that cause pain, swelling, and inflammation.

How Proxym-XT Tablet Works

Proxym-XT Tablet contains Etodolac and Paracetamol. Etodolac is a non-steroidal anti-inflammatory drug (NSAID), and Paracetamol is an analgesic. They act by blocking the production of chemical substances called prostaglandins that cause pain, swelling, and inflammation. The inhibition of these substances can cause a decrease in symptoms such as pain, joint stiffness, and tenderness.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Proxym-XT Tablet

Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Before taking Proxym-XT Tablet , inform your doctor if you have high blood pressure, high cholesterol, diabetes, heart disease, heart attack or stroke, blood clot, stomach bleeding, asthma, edema (fluid overload), smoking habit, and liver, kidney disease. Inform your doctor immediately if you cough up or vomit blood or notice black or tarry stools, as it can be a sign of stomach bleeding. Proxym-XT Tablet increases skin sensitivity to the sun, so avoid prolonged exposure to sunlight, sunlamps, and tanning beds.

Drug-Drug Interactions

EtodolacKetorolac

Critical

EtodolacMeloxicam

Critical

Drug-Drug Interactions

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EtodolacKetorolac

Critical

How does the drug interact with Proxym-XT 200 mg/325 mg Tablet:
Using ketorolac together with Proxym-XT 200 mg/325 mg Tablet may increase the risk of side effects in the gastrointestinal tract (inflammation, bleeding and ulceration).

How to manage the interaction:
Taking Proxym-XT 200 mg/325 mg Tablet with Ketorolac is not recommended, but it can be taken together if prescribed by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.

EtodolacMeloxicam

Critical

How does the drug interact with Proxym-XT 200 mg/325 mg Tablet:
Co-administration of Proxym-XT 200 mg/325 mg Tablet with Meloxicam can raise the adverse consequences in the digestive system, including inflammation, bleeding, ulceration, and, in rare cases, perforation(rupture).

How to manage the interaction:
Taking Meloxicam with Proxym-XT 200 mg/325 mg Tablet is not recommended can result in an interaction, it can be taken if a doctor has advised it. If you notice any of these symptoms like dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness consult a doctor. Do not discontinue any medications without consulting a doctor.

EtodolacTacrolimus

Severe

How does the drug interact with Proxym-XT 200 mg/325 mg Tablet:
Taking tacrolimus with Proxym-XT 200 mg/325 mg Tablet may increase risk of kidney problems.

How to manage the interaction:
Although taking tacrolimus and Proxym-XT 200 mg/325 mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.

EtodolacIbuprofen

Severe

How does the drug interact with Proxym-XT 200 mg/325 mg Tablet:
Use of Proxym-XT 200 mg/325 mg Tablet and Ibuprofen can increase the risk of side effects in the gastrointestinal tract (inflammation, bleeding, ulceration, and rarely perforation).

How to manage the interaction:
Taking Proxym-XT 200 mg/325 mg Tablet and Ibuprofen together can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.

EtodolacPhenylbutazone

Severe

How does the drug interact with Proxym-XT 200 mg/325 mg Tablet:
Taking phenylbutazone with Proxym-XT 200 mg/325 mg Tablet may raise the risk of gastrointestinal adverse effects (inflammation, bleeding, ulceration, and, in rare cases, perforation).

How to manage the interaction:
Although taking Proxym-XT 200 mg/325 mg Tablet and Phenylbutazone together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, a severe headache, and/or weakness, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.

EtodolacTinzaparin

Severe

How does the drug interact with Proxym-XT 200 mg/325 mg Tablet:
Use of tinzaparin with Proxym-XT 200 mg/325 mg Tablet may raise the risk of bleeding problems.

How to manage the interaction:
There may be a possibility of interaction between Proxym-XT 200 mg/325 mg Tablet and Tinzaparin, but it can be taken if prescribed by a doctor. However, if you experience unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness while taking these drugs, consult doctor immediately. Do not discontinue any medications without consulting a doctor.

EtodolacSirolimus

Severe

How does the drug interact with Proxym-XT 200 mg/325 mg Tablet:
Coadministration of Proxym-XT 200 mg/325 mg Tablet and Sirolimus can increase the risk or severity of kidney problems.

How to manage the interaction:
Although taking Sirolimus and Proxym-XT 200 mg/325 mg Tablet together can cause an interaction, it can be taken if a doctor has suggested it. However, consult a doctor if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm. Do not discontinue any medications without a doctor's advice.

EtodolacIomeprol

Severe

How does the drug interact with Proxym-XT 200 mg/325 mg Tablet:
Taking Proxym-XT 200 mg/325 mg Tablet and Iomeprol can increase the risk of kidney damage.

How to manage the interaction:
Taking Proxym-XT 200 mg/325 mg Tablet with Iomeprol together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor immediately. Drink lots of fluid after the procedure to stay hydrated and to flush the contrast agent out of your kidneys. Do not stop using any medications without talking to a doctor.

EtodolacFlurbiprofen

Severe

How does the drug interact with Proxym-XT 200 mg/325 mg Tablet:
Taking Flurbiprofen with Proxym-XT 200 mg/325 mg Tablet can increase the risk of side effects (inflammation, bleeding, ulceration, and rarely perforation).

How to manage the interaction:
Taking Proxym-XT 200 mg/325 mg Tablet with Flurbiprofen together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.

EtodolacDalteparin

Severe

How does the drug interact with Proxym-XT 200 mg/325 mg Tablet:
Taking Proxym-XT 200 mg/325 mg Tablet with Dalteparin can increase the risk of bleeding and hemorrhage.

How to manage the interaction:
Although there is a possible interaction between Proxym-XT 200 mg/325 mg Tablet and Dalteparin, you can take these medicines together if prescribed by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do stretching, low impact aerobic exercise like walking on the treadmill, bike riding, and swimming. You can also strengthen your muscles by lifting light weights.
In the chronic conditions of arthritis or joint pain, try to include fish like salmon, trout, tuna, and sardines. These fishes are enriched with omega-3 fatty acids that minimize levels of chemicals called cytokines, which ramp up inflammation.
Your sitting posture is important, especially when you have pain and inflammation. Try to sit as little as possible, and only for a short duration of time. Long-term immobility is harmful in conditions like arthritis. Use back support like a rolled-up towel at the back of your spine curve to minimize pain. Keep your knees and hips at a right angle. Besides this, you can also use a footrest if required.

Habit Forming

No

Therapeutic Class

ANALGESICS