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  3. RABEPRIDE 10MG TABLET

RABEPRIDE 10MG TABLET, Pack of 10
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
RABEPRIDE 10MG TABLET is used to lower the increased level of stomach acid. It treats GERD (gastro-oesophagal reflux disease), and peptic ulcers. It contains Rabeprazole and Itopride, which blocks acid production and provides relief from heartburn and acid-related digestion. Also, it works on the part of the brain that is responsible for controlling vomiting. It increases the movement of stomach and intestines in the upper digestive tract. Thus, it helps prevent acid reflux, thereby relieving acidity. Sometimes, it may cause common side effects such as headache, nausea, stomach pain, dizziness, and diarrhoea. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

ITOPRIDE-150MG + RABEPRAZOLE-10MG

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About RABEPRIDE 10MG TABLET

RABEPRIDE 10MG TABLET is used to lower the increased level of stomach acid. It treats GERD (gastro-oesophagal reflux disease), and peptic ulcers. Gastroesophageal reflux disease (GERD) occurs when stomach acid frequently flows back into the food pipe (oesophagus). Peptic ulcers are sores that develop on the inner lining of the intestine and stomach.

RABEPRIDE 10MG TABLET is a combination of two drugs: Rabeprazole and Itopride. Rabeprazole is a proton pump inhibitor (PPI) that works by blocking the action of an enzyme called gastric proton pump, which is responsible for acid production. It minimizes the release of acid from the stomach, which provides relief from heartburn and acid-related digestion. While Itopride works on the part of the brain that is responsible for controlling vomiting.  It increases gastric emp undying improves gastric sensitivity and tension by increasing the stomach's movement and intestines in the upper digestive tract. It also has anti-emetic action. Together, RABEPRIDE 10MG TABLET helps prevent acid reflux, thereby relieving acidity.

Take RABEPRIDE 10MG TABLET 30-60 minutes before food. Do not chew or break the tablet; swallow it as a whole with a glass of water. You are advised to take RABEPRIDE 10MG TABLET for as long as your doctor has prescribed it for you, depending on your medical condition. Sometimes, you may experience common side effects such as headache, nausea, stomach pain, dizziness, and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Inform your doctor before taking RABEPRIDE 10MG TABLET if you have a history of gastrointestinal bleeding, mechanical perforation/obstruction, or movement disorder. On long-term treatment, RABEPRIDE 10MG TABLET may cause osteoporosis and hypomagnesemia (low levels of magnesium). Do not take RABEPRIDE 10MG TABLET if you are pregnant or breastfeeding unless prescribed by the doctor. RABEPRIDE 10MG TABLET causes drowsiness, so drive only if you are alert. RABEPRIDE 10MG TABLET should not be given to children as safety has not been established. Avoid consuming alcohol with RABEPRIDE 10MG TABLET as it can lead to increased drowsiness and increased acid production. 

Uses of RABEPRIDE 10MG TABLET

Treatment of Hyperacidity, Gastro-oesophageal reflux disease, Peptic ulcer.

Directions for Use

• Take RABEPRIDE 10MG TABLET with or without food or as advised by a doctor.• Follow your doctor's instructions on the dosage and timing of this medication, to ensure the safety.• Swallow the medicine as a whole with glass of water.• Do not crush, break, or chew it.

Medicinal Benefits

RABEPRIDE 10MG TABLET is a combination of two drugs:  Rabeprazole and Itopride. Rabeprazole is a proton pump inhibitor (PPI) that works by blocking the action of an enzyme called gastric proton pump, which is responsible for acid production. It minimizes the release of acid from the stomach, which provides relief from heartburn and acid-related digestion. While Itopride works on the part of the brain responsible for controlling vomiting.  It increases gastric emptying and improves gastric sensitivity and tension by increasing the stomach's movement and intestines in the upper digestive tract. It also has anti-emetic action. Together, RABEPRIDE 10MG TABLET helps prevent acid reflux, thereby relieving acidity.
 

How RABEPRIDE 10MG TABLET Works

RABEPRIDE 10MG TABLET is a combination of two drugs:  Rabeprazole and Itopride. Rabeprazole is a proton pump inhibitor (PPI) that works by blocking the action of an enzyme called gastric proton pump, which is responsible for acid production. It minimizes the release of acid from the stomach, which provides relief from heartburn and acid-related digestion. While Itopride works on the part of the brain responsible for controlling vomiting.  It increases gastric emptying and improves gastric sensitivity and tension by increasing the stomach's movement and intestines in the upper digestive tract. It also has anti-emetic action. Together, RABEPRIDE 10MG TABLET helps prevent acid reflux, thereby relieving acidity.

Storage

Keep RABEPRIDE 10MG TABLET out of reach and sight of children.
Side effects of Rabepride 10mg Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
  • Apply a hot/cold pack to the affected area.
  • Doing gentle exercises can help cope with pain by stretching muscles.
  • Get enough sleep. It helps enhance mood and lower pain sensitivity.
  • Avoid alcohol, smoking and tobacco as they can increase pain.
  • Follow a well-balanced meal.
  • Meditation and massages may also help with pain.
  • Drink warm fluids such as warm water with honey, broth, soup or herbal tea to soothe sore throat.
  • Gargle with warm salt water.
  • Suck on lozenges to increase the production of saliva and soothe your throat.
  • Use a humidifier to soothe sore throat as it adds moisture to the air and makes breathing easier.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.

What if I have taken an overdose of RABEPRIDE 10MG TABLET

Do not take more than the prescribed dose of RABEPRIDE 10MG TABLET as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take RABEPRIDE 10MG TABLET if you are allergic to any of its contents. Inform your doctor before taking RABEPRIDE 10MG TABLET if you have a history of gastrointestinal bleeding, mechanical perforation/obstruction, or movement disorder. RABEPRIDE 10MG TABLET may cause osteoporosis on long-term treatment. RABEPRIDE 10MG TABLET may also cause hypomagnesemia (low magnesium). Do not take RABEPRIDE 10MG TABLET if you are pregnant or breastfeeding unless prescribed by the doctor. RABEPRIDE 10MG TABLET causes dizziness, so drive only if you are alert. RABEPRIDE 10MG TABLET should not be given to children as safety has not been established. Avoid consuming alcohol along with RABEPRIDE 10MG TABLET as it could lead to increased drowsiness and elevate stomach acid production. Keep your doctor informed about all the medicines and your health condition to rule out any side effects.  Consult your doctor if you experience unexplained weight loss, stomach pain, indigestion, vomit food or blood, or if you pass black stools. On long-term treatment, RABEPRIDE 10MG TABLET may cause osteoporosis and hypomagnesemia (low levels of magnesium), and may reduce the absorption of vitamin B12.

Drug-Drug Interactions

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RabeprazoleRilpivirine
Critical
RabeprazoleErlotinib
Critical

Drug-Drug Interactions

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RabeprazoleRilpivirine
Critical
How does the drug interact with Rabepride 10mg Tablet:
Co-administration of Rabepride 10mg Tablet can make Rilpivirine less effective by reducing its absorption in the body.

How to manage the interaction:
Taking Rabepride 10mg Tablet with Rilpivirine is not recommended, but can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.
RabeprazoleErlotinib
Critical
How does the drug interact with Rabepride 10mg Tablet:
When used in combination with erlotinib, Rabepride 10mg Tablet may prevent the absorption of erlotinib into the circulation, which might make erlotinib less effective in treating cancer.

How to manage the interaction:
Taking Rabepride 10mg Tablet with Erlotinib is not recommended as it can result in an interaction, it should be taken only if a doctor has advised it. Do not stop using any medications without consulting a doctor.
RabeprazoleAtazanavir
Severe
How does the drug interact with Rabepride 10mg Tablet:
Co-administration of Atazanavir's blood levels and absorption can both be affected by Rabepride 10mg Tablet, which decreases the atazanavir's ability to treat HIV.

How to manage the interaction:
Although taking Rabepride 10mg Tablet and atazanavir together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
RabeprazolePazopanib
Severe
How does the drug interact with Rabepride 10mg Tablet:
Taking Rabepride 10mg Tablet together with Pazopanib can result in a decreased effectiveness of Pazopanib in treating the disease.

How to manage the interaction:
Although taking Rabepride 10mg Tablet and Pazopanib together can result in an interaction, but can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without talking to a doctor.
RabeprazoleGefitinib
Severe
How does the drug interact with Rabepride 10mg Tablet:
Taking Rabepride 10mg Tablet together with Gefitinib results in decreased levels of gefitinib in your blood. This can result in a decreased effectiveness of gefitinib in treating the disease.

How to manage the interaction:
Although taking Rabepride 10mg Tablet and Gefitinib together can possibly result in an interaction, it can be taken if your doctor has prescribed it. To lessen the effects of the interaction, it is advised that you take gefitinib 12 hours before or 12 hours after Rabepride 10mg Tablet. Do not discontinue any medications without a doctor's advice.
RabeprazoleDasatinib
Severe
How does the drug interact with Rabepride 10mg Tablet:
Taking Rabepride 10mg Tablet together with Dasatinib results in decreased levels of Dasatinib and its effectiveness.

How to manage the interaction:
Although taking Rabepride 10mg Tablet and Dasatinib together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
RabeprazoleAcalabrutinib
Severe
How does the drug interact with Rabepride 10mg Tablet:
Taking Rabepride 10mg Tablet together with Acalabrutinib results in a decreased effectiveness of Acalabrutinib.

How to manage the interaction:
Although taking Rabepride 10mg Tablet and Acalabrutinib together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
RabeprazoleMethotrexate
Severe
How does the drug interact with Rabepride 10mg Tablet:
Co-administration of Methotrexate with Rabepride 10mg Tablet can increase the blood levels and side effects of Methotrexate.

How to manage the interaction:
Although there is a possible interaction between Rabepride 10mg Tablet and Methotrexate, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without consulting a doctor.
RabeprazoleIdelalisib
Severe
How does the drug interact with Rabepride 10mg Tablet:
When Rabepride 10mg Tablet and Idelalisib are taken in combination, Idelalisib may increase the level or impact of Rabepride 10mg Tablet.

How to manage the interaction:
Although taking Rabepride 10mg Tablet and Idelalisib together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
RabeprazolePhenytoin
Severe
How does the drug interact with Rabepride 10mg Tablet:
When Phenytoin and Rabepride 10mg Tablet are taken in combination, Phenytoin will reduce the concentration or impact of Rabepride 10mg Tablet.

How to manage the interaction:
Although taking Phenytoin and Rabepride 10mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat smaller meals more often.
  • Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
  • Maintain a healthy weight by regular exercising.
  • Avoid lying down after eating.
  • Avoid tight-fitting clothes.
  • Maintain a healthy weight by regular exercising.
  • Practice relaxation techniques and avoid stress by doing yoga or meditation.
  • Avoid foods such as high-fat, spicy chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea and soda. 
  • Avoid sitting continuously, as it may trigger acidity. Take a break of 5minutes break every hour by doing brisk walking or stretching.

Habit Forming

No

Therapeutic Class

GASTROINTESTINAL AGENTS
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Alcohol

Unsafe

Avoid consumption of alcohol while taking RABEPRIDE 10MG TABLET. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.

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Pregnancy

Caution

Consult your doctor before taking RABEPRIDE 10MG TABLET if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Breast Feeding

Caution

Consult your doctor before taking RABEPRIDE 10MG TABLET; your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Caution

RABEPRIDE 10MG TABLET causes dizziness. Do not drive or operate machinery unless you are alert.

bannner image

Liver

Caution

Dose adjustment may be needed. Consult your doctor before taking RABEPRIDE 10MG TABLET if you have a liver impairment or any concerns.

bannner image

Kidney

Caution

Dose adjustment may be needed. Consult your doctor before taking RABEPRIDE 10MG TABLET if you have kidney impairment or any concerns.

bannner image

Children

Unsafe

RABEPRIDE 10MG TABLET should not be given to children as safety and effectiveness were not established.

Have a query?

FAQs

RABEPRIDE 10MG TABLET is used to treat GERD (gastro-oesophagal reflux disease), and peptic ulcers.

RABEPRIDE 10MG TABLET is a combination of two drugs: Â Rabeprazole and Itopride. Rabeprazole is a proton pump inhibitor (PPI), that works by blocking the action of an enzyme called gastric proton pump, which is responsible for the production of acid. It minimizes the release of acid from the stomach, which provides relief from heartburn and acid-related digestion. While Itopride works on the part of the brain responsible for controlling vomiting. Â It increases gastric emptying, and improves gastric sensitivity and tension by increasing the movement of the stomach, and intestines in the upper digestive tract. It also has anti-emetic action. Together, RABEPRIDE 10MG TABLET helps prevent acid reflux and provide relief from acidity.

Talk to your doctor if you do not feel better even after taking RABEPRIDE 10MG TABLET for 14 days. Do not take RABEPRIDE 10MG TABLET for longer durations unless prescribed by the doctor.

Diarrhoea might be a side-effect of RABEPRIDE 10MG TABLET. Drink enough fluids and eat fibre-rich food if you experience diarrhoea. If you find blood in your stools (tarry stools) or if you experience excess diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

Avoid or limit the consumption of alcohol while taking RABEPRIDE 10MG TABLET as it may lead to increased dizziness. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.

Avoid lying down immediately after meals to prevent acid reflux. Raise the head of the bed 10-20cm by putting a pillow so that the head and chest are above the waist. This helps in preventing acid reflux.

RABEPRIDE 10MG TABLET contains lactose monohydrate, so a person who is intolerant to sugar should tell their doctor before taking this medicine.

Consult your doctor before taking RABEPRIDE 10MG TABLET if you are pregnant or planning for pregnancy. Your doctor will prescribe RABEPRIDE 10MG TABLET only if the benefits outweigh the risks.

The common side effects of RABEPRIDE 10MG TABLET include headache, nausea, stomach pain, dizziness, and diarrhoea. If these side effects persist or worsen, please consult your doctor.

Take RABEPRIDE 10MG TABLET at the time recommended by your doctor. It is usually best to take it 30 to 60 minutes before breakfast, as this helps the medication work effectively to reduce stomach acid.

RABEPRIDE 10MG TABLET is contraindicated in people who are allergic to any of its components. Inform your doctor before taking RABEPRIDE 10MG TABLET if you have a history of gastrointestinal bleeding, mechanical perforation or obstruction, or a movement disorder. Do not take RABEPRIDE 10MG TABLET if you are pregnant or breastfeeding unless prescribed by a doctor.

RABEPRIDE 10MG TABLET may cause dizziness as a side effect. If you feel dizzy after taking RABEPRIDE 10MG TABLET, avoid driving or using machinery until you feel alert again. If the dizziness continues, please contact your doctor.

RABEPRIDE 10MG TABLET contains rabeprazole (a proton pump inhibitor), which may increase the risk of fractures, particularly of the hip, wrist, and spine, when used long-term or in multiple daily doses, especially in older adults. This is primarily due to reduced calcium absorption. If you are using RABEPRIDE 10MG TABLET for an extended period, monitor your bone health regularly (e.g., calcium levels, bone density) and talk to your doctor if you have any concerns.

RABEPRIDE 10MG TABLET is not usually known to affect your ability to drive. However, if you experience side effects like dizziness or drowsiness after taking RABEPRIDE 10MG TABLET, it is best to avoid driving.

RABEPRIDE 10MG TABLET should be stored at room temperature, away from direct sunlight and moisture. Keep it out of reach of children.

Country of origin

India
Other Info - RAB0198

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:42 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://mri.cts-mrp.eu/human/downloads/SK_H_0159_001_FinalPI_1of3.pdf
  2. https://core.ac.uk/download/pdf/194178089.pdf

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