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compositionComposition:RANITIDINE-300MG
prescription
Prescription Medicine
info
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Ran-OD Tablet 10's is used to treat indigestion, heartburn and acid reflux. It is also used for gastro-oesophageal reflux disease (GORD) when you get acid reflux. It is also used to prevent and treat stomach ulcers. It contains Ranitidine, which helps reduce stomach acid. It may cause common side effects like headache, diarrhoea, constipation, and shortness of breath. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

RANITIDINE-300MG

Manufacturer/Marketer :

Eldroga Life Sciences Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Ran-OD Tablet 10's

Ran-OD Tablet 10's reduces the production of acid in the stomach. Historically, it was used to treat conditions such as stomach ulcers, gastroesophageal reflux disease (GERD), irritation of the food pipe (esophagitis), and other acid-related digestive disorders. By lowering stomach acid levels, it helped the lining of the stomach and food pipe heal and reduced symptoms such as heartburn and acid reflux.

When it was prescribed, patients were generally advised to take it consistently at the same times each day. It could be taken with or without food, and lifestyle measures such as eating smaller meals, avoiding trigger foods, maintaining a healthy weight, and avoiding tobacco use were often recommended to improve symptom control.

Most people tolerated the medication well, although side effects such as headache, constipation, diarrhea, or mild stomach discomfort could occur. Serious symptoms such as severe abdominal pain, unusual bleeding, jaundice (yellowing of the skin or eyes), or significant changes in mental status required prompt medical evaluation.

Before using Ran-OD Tablet 10's, healthcare providers considered factors such as kidney function, liver health, and the presence of certain rare medical conditions such as porphyria.

Ran-OD Tablet 10's was previously available both by prescription and as an over-the-counter (OTC) medicine in India for the treatment of heartburn, acid reflux, and indigestion. Patients who previously self-medicated with Ran-OD Tablet 10's should not attempt to obtain or use old supplies. Instead, consult a doctor or pharmacist about currently available alternatives, such as famotidine or proton pump inhibitors, which may be more appropriate depending on individual symptoms and medical history. Patients who previously relied on Ran-OD Tablet 10's may feel uncertain about changing treatments, but several effective and widely available alternatives are now used to manage heartburn, acid reflux, and other acid-related conditions. 

Important Safety Notice: Ran-OD Tablet 10's has been withdrawn, recalled, or discontinued in many countries, including India, due to concerns about contamination with N-nitrosodimethylamine (NDMA), a probable human carcinogen. This article is provided for educational and historical reference only. Patients should not use old supplies of Ran-OD Tablet 10's or attempt to obtain the medicine from unofficial sources. If you require treatment for heartburn, acid reflux, ulcers, or other acid-related conditions, consult a doctor or pharmacist about currently recommended alternatives. 
 

Uses of Ran-OD Tablet 10's

Ran-OD Tablet 10's is commonly used to reduce excess stomach acid and manage a variety of acid-related digestive conditions, including:

  • Gastroesophageal Reflux Disease (GERD): Ran-OD Tablet 10's helps by lowering stomach acid production, which prevents the acid from backflowing into the food pipe and causing painful irritation.
  • Stomach and Intestinal Ulcers: It reduces the harsh acidic environment in your stomach, allowing active ulcers in the stomach lining or upper intestine to heal and preventing new ones from forming.
  • Heartburn and Acid Indigestion: It provides targeted relief from the burning sensation in your chest and throat by stopping the excess acid that triggers these symptoms.
  • Zollinger-Ellison Syndrome: In this rare condition where the stomach produces extreme amounts of acid, Ran-OD Tablet 10's helps control and lower acid levels to protect your digestive tract.
     

Key Benefits

Ran-OD Tablet 10's offered several benefits by reducing stomach acid production and promoting healing of the digestive tract, including:

  • Relief from Acid-Related Discomfort: By lowering excess stomach acid, Ran-OD Tablet 10's helped reduce symptoms such as heartburn, acid reflux, indigestion, and upper abdominal discomfort, allowing many patients to eat and drink more comfortably.
  • Improved Sleep Quality: Many people experience worse reflux symptoms when lying down at night. By reducing acid production, this medicine helped decrease nighttime symptoms and improve sleep quality.
  • Faster Healing of Irritated Tissues: It helped soothe and heal irritation in the food pipe and stomach lining caused by excessive acid exposure.
Side effects of Ran-OD Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Directions for Use

For the best and safest results, always follow the exact instructions provided by your doctor or pharmacist. Use the following steps to take your medicine correctly:

  • Take this medication by mouth, usually once or twice a day as prescribed.
  • Swallow the tablet or capsule whole with a full glass of water. Do not crush, chew, or break it unless your doctor specifically tells you to do so.
  • If you are using the liquid form, measure the dose carefully using a medical dose-measuring spoon or syringe, not a regular household spoon.
  • You can take this medicine with or without food.
  • Do not change your dose or stop taking this medication early, even if you start to feel better, without consulting your doctor first.
     

Important: Because Ran-OD Tablet 10's has been withdrawn from many markets, including India, this information is provided for historical and educational purposes only. Patients should not use old or previously stored supplies and should speak with a healthcare professional about currently available alternatives.
 

How Ran-OD Tablet 10's Works

Ran-OD Tablet 10's contains ranitidine, which belongs to a group of medicines known as H2-receptor antagonists (H2 blockers). It is used to reduce the production of stomach acid and provide relief from conditions associated with excess acid secretion. Ranitidine works by blocking histamine H2 receptors located on the acid-producing cells of the stomach. Histamine is a natural chemical that stimulates these cells to release stomach acid during digestion. By preventing histamine from activating these receptors, ranitidine decreases both the amount and acidity of stomach acid produced by the stomach. This helps reduce irritation and damage caused by excess acid. With lower acid levels, the lining of the stomach and food pipe is given an opportunity to heal. This helps relieve symptoms such as heartburn, acid reflux, indigestion, and discomfort associated with stomach and intestinal ulcers. Together, these actions help control excess stomach acid, promote healing of irritated tissues, and provide relief from acid-related digestive conditions.
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Alcohol

Unsafe

Drinking alcohol with Ran-OD Tablet 10's may cause dehydration and elevate the level of stomach acid, thereby decreasing its efficacy. So try to avoid consuming alcohol.

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Pregnancy

Consult your doctor

Ran-OD Tablet 10's should be used in pregnant women only if clinically needed, and the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Ran-OD Tablet 10's should be used in nursing women only if clinically needed, and the benefits outweigh the risks.

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Driving

Caution

Ran-OD Tablet 10's has no or negligible influence on the ability to drive and use machines. In some cases, Ran-OD Tablet 10's may cause dizziness and sleep. If you observe these symptoms, do not drive or operate machinery until you feel better.

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Liver

Consult your doctor

If you have or had a history or evidence of any liver-related diseases, please consult the doctor before taking medicine.

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Kidney

Consult your doctor

If you have or had a history or evidence of any kidney-related diseases, please consult the doctor before taking medicine.

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Children

Safe if prescribed

The dose needs to be adjusted based on your child’s weight.

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Heart

Safe if prescribed

Ran-OD Tablet 10's is safe for use in heart patients if recommended by the physician.

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Geriatrics

Unsafe

Ran-OD Tablet 10's should be avoided in geriatric patients as it can cause serious adverse effects.

What if I have taken an overdose of Ran-OD Tablet 10's

If you accidentally take more Ran-OD Tablet 10's than prescribed, seek immediate medical attention or contact a poison control center right away. Symptoms following an overdose may vary and are not always predictable. Possible symptoms can include dizziness, drowsiness, nausea, vomiting, difficulty walking, low blood pressure, or changes in heart rhythm. Medical assessment is recommended whenever a significant overdose is suspected.

Diet & Lifestyle Advise

  • Avoid trigger foods: Limit your intake of spicy, fatty, acidic (like citrus and tomatoes), or highly seasoned foods, as well as chocolate and caffeine, which can trigger excess acid production.
  • Eat smaller meals: Large meals can put pressure on the valve between your stomach and esophagus. Try eating smaller, more frequent portions instead.
  • Stay upright after eating: Avoid lying down, bending over, or going to bed for at least two to three hours after a meal to prevent acid from traveling back up your throat.
  • Elevate your head during sleep: Raise the head of your bed by six inches using bed risers or a wedge pillow to keep stomach acid down while you sleep.
  • Avoid tight clothing: Wearing tight belts or clothes that constrict your abdomen can push acid upward into your esophagus.
    Quit smoking: Nicotine can weaken the muscle valve that keeps acid inside your stomach. Talk to your doctor about ways to quit.
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How Soon It Starts Working

The time required for Ran-OD Tablet 10's to start to work: Ran-OD Tablet 10's ideally shows its action within 1 hour after administration. The time for which the effects of Ran-OD Tablet 10's last: The effect of Ran-OD Tablet 10's lasts for 4 to 6 hours.

What if you forget to take Ran-OD Tablet 10's

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store Ran-OD Tablet 10's at controlled room temperature, ideally between 15°C and 30°C (59°F to 86°F). • Keep the medication in its original container, tightly closed, to protect it from moisture and direct light.

Drug Warnings

  • Check Before Use: Inspect the medication before taking it; do not use tablets that are broken or discoloured, or liquid formulations that appear cloudy or contain particles.
  • Monitor Your Symptoms: If your reflux or heartburn symptoms do not improve after 14 days, or if they worsen, seek medical evaluation, as persistent symptoms may indicate a more serious underlying condition requiring further investigation.
  • Driving and Alertness: Be cautious when driving or performing activities requiring alertness until you know how the medicine affects you.
  • Avoid Additional Acid-Reducing Medicines: Do not take additional acid-reducing medicines unless specifically advised by your healthcare provider.
  • Before Allergy Testing: Inform your doctor before allergy testing, as certain medications may affect test results.
     

Important: Because Ran-OD Tablet 10's has been withdrawn from many markets due to NDMA contamination concerns, patients should not start or restart this medication without consulting a healthcare professional. Ask your doctor or pharmacist about currently recommended alternatives.
 

Drug-Drug Interactions

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Drug-Drug Interactions

Ran-OD Tablet 10's may interact with certain medications, potentially affecting their absorption, effectiveness, or side-effect profile, including:

  • Ketoconazole and itraconazole: Reduced stomach acid can decrease the absorption and effectiveness of these antifungal medicines.
  • Warfarin: Monitoring may be required because changes in blood-thinning effects have occasionally been reported.
  • Procainamide: Ran-OD Tablet 10's may increase blood levels of procainamide and its metabolites, increasing the risk of side effects.
  • Certain HIV medications: Reduced stomach acid may affect the absorption of some antiviral medicines.
  • Other prescription medicines: Always provide your healthcare provider with a complete list of medicines, supplements, and herbal products you use.


Drug-Food Interactions

Certain foods and beverages may worsen acid-related symptoms or reduce overall symptom control, including:

  • Alcohol: Drinking alcohol can irritate the stomach lining and worsen heartburn, reflux, and indigestion symptoms.
  • Caffeinated beverages: Coffee, tea, energy drinks, and some soft drinks may increase acid-related symptoms in sensitive individuals.
  • Acidic foods and drinks: Citrus fruits, citrus juices, tomatoes, and tomato-based products may aggravate heartburn and reflux symptoms.
  • Spicy or fatty foods: These foods can trigger or worsen reflux and indigestion in some people and may reduce overall symptom control.

Drug-Disease Interactions

Certain medical conditions may require special precautions when using Ran-OD Tablet 10's, including:

  • Kidney Disease: Ran-OD Tablet 10's is primarily filtered out of the body by the kidneys. People with kidney problems may clear the medicine more slowly, increasing the risk of side effects. Dose adjustments may be required.
  • Liver Disease: Although the medicine is primarily eliminated through the kidneys, a portion is processed by the liver. People with significant liver disease may require additional monitoring and medical supervision.
  • Porphyria: Ran-OD Tablet 10's may trigger acute attacks in people with porphyria, a rare inherited condition that affects how the body produces important components of blood. It should be avoided or used only under specialist supervision in affected individuals.
     
RanitidineMesalazine
Severe
RanitidineRilpivirine
Severe

Drug-Drug Interactions

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RanitidineMesalazine
Severe
How does the drug interact with Ran-OD Tablet:
Co-administration of Ran-OD Tablet with Mesalazine can decrease the levels of Mesalazine, which may be less effective in treating a condition.

How to manage the interaction:
There may be a possible interaction between Mesalazine with Ran-OD Tablet, but they can be taken together if a doctor has prescribed them. Do not discontinue any medications without consulting a doctor.
RanitidineRilpivirine
Severe
How does the drug interact with Ran-OD Tablet:
Coadministration of Rilpivirine with Ran-OD Tablet can reduce the acidity levels in the stomach and also decrease the effectiveness of Rilpivirine.

How to manage the interaction:
Although taking Ran-OD Tablet together with Rilpivirine can possibly result in an interaction, they can be taken together if prescribed by your doctor. To reduce the chance of interaction, take Ran-OD Tablet at least 12 hours before or 4 hours after taking rilpivirine. Do not discontinue any medicine without consulting a doctor.
RanitidineDasatinib
Severe
How does the drug interact with Ran-OD Tablet:
Taking Ran-OD Tablet and Dasatinib together reduces the effectiveness of Dasatinib.

How to manage the interaction:
Although taking Ran-OD Tablet together with Dasatinib can result in an interaction, they can be taken together if prescribed by a doctor. However, contact a doctor if you experience any unusual symptoms. Do not discontinue any medicine without consulting a doctor.
RanitidinePazopanib
Severe
How does the drug interact with Ran-OD Tablet:
Using Pazopanib with Ran-OD Tablet can reduce the effectiveness of pazopanib

How to manage the interaction:
Although taking Ran-OD Tablet together with Pazopanib can possibly result in an interaction, but can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
RanitidineGefitinib
Severe
How does the drug interact with Ran-OD Tablet:
Coadministration of Gefitinib with Ran-OD Tablet can reduce the acidity levels in the stomach and also decrease the effectiveness of gefitinib

How to manage the interaction:
Taking Gefitinib with Ran-OD Tablet together can possibly result in an interaction, it can be taken if your doctor has advised it. It is recommended that gefitinib is either taken 6 hours before or 6 hours after Ran-OD Tablet to help minimize the impact of the interaction. Do not stop using any medications without first talking to your doctor.
RanitidineLoperamide
Severe
How does the drug interact with Ran-OD Tablet:
Coadministration of loperamide with Ran-OD Tablet may significantly increase the blood levels of loperamide. This can increase the risk of serious side effect like irregular heart rhythm.

How to manage the interaction:
Although taking loperamide with Ran-OD Tablet together can result in an interaction, they can be taken if a doctor has prescribed it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
RanitidineAtazanavir
Severe
How does the drug interact with Ran-OD Tablet:
Taking atazanavir with Ran-OD Tablet can reduce the effectiveness of atazanavir.

How to manage the interaction:
Although taking Ran-OD Tablet together with Atazanavir can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor if you experience unusual symptoms. Do not discontinue any medicine without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[GASTROINTESTINAL AGENTS]

FAQs

Ran-OD Tablet 10's is used to treat indigestion, heartburn and acid reflux. It is also used for gastro-oesophageal reflux disease (GORD) when you get acid reflux. Ran-OD Tablet 10's is also used to prevent and treat stomach ulcers. Often Ran-OD Tablet 10's is taken for a rare condition caused by a pancreatic or intestine tumour called Zollinger-Ellison Syndrome.
Ranitidine belongs to a class of drugs known as H2 receptor antagonists (gastrointestinal agents). Ran-OD Tablet 10's works by lessening the quantity of acid produced in your stomach.
Yes, you can take Ran-OD Tablet 10's with or without food. If you find that it upsets your stomach, taking it with meals may help. Talk to your doctor or pharmacist if you have questions.
Ran-OD Tablet 10's typically began reducing stomach acid within about one hour of administration, with effects lasting up to 12 hours. However, improvement in conditions such as GERD, oesophagitis, or ulcers often required several days to weeks of consistent treatment. If symptoms persisted or worsened despite treatment, medical evaluation was recommended.
Ran-OD Tablet 10's may have some serious side effects, but these are rare. These side effects may include hives, skin rash, itching, and difficulty in breathing. Inform your doctor in case you notice any of these side effects.
No, Ran-OD Tablet 10's prevents excess production of stomach acid, causing acid reflux and heartburn. If blood is coming in your stool or mucous, immediately contact the doctor.
The duration of the Ran-OD Tablet 10's treatment depends on your specific condition and the doctor's recommendation.
Ran-OD Tablet 10's is a common treatment for gastritis. However, if you have gastritis, it's essential to consult with a healthcare professional before using Ran-OD Tablet 10's, especially for the long term. They can provide an accurate diagnosis and recommend appropriate alternative therapies.
Ran-OD Tablet 10's typically starts working within 30 minutes to 1 hour. However, achieving complete symptom relief may take several days of consistent use.
No, the Ran-OD Tablet 10's is not used for loose motion.
Ran-OD Tablet 10's typically starts working within 30 minutes. Individual responses may vary from person to person.
Yes, in most cases you can take an antacid alongside this medicine for immediate, short-term relief. It is best to space them out by taking the antacid at least one hour before or after taking Ran-OD Tablet 10's. Talk to your doctor or pharmacist for specific timing.
Yes, it can be used in children; the dose must be adjusted based on your child's weight. If your child is experiencing heartburn, acid reflux, or other digestive issues, it's important to consult with a paediatrician. They can provide an accurate diagnosis and recommend appropriate alternative treatments that are safe and effective for children.
Yes, Ran-OD Tablet 10's can cause constipation in some people. While constipation is not a common side effect of Ranitidine, it can occur in some individuals.
Ran-OD Tablet 10's contains Ranitidine (a histamine-2 (H2) receptor blocker), whereas PAN 40 contains Pantoprazole (proton-pump inhibitors). Both are used to treat heartburn, ulcers, and other gastrointestinal issues. Still, they have different mechanisms of action and are in different drug classes.
Do not take Ran-OD Tablet 10's for longer than two weeks unless your doctor tells you to. Long-term use of Ranitidine may increase the risk of side effects. If you're taking Ranitidine, discussing this with your doctor and exploring alternative options is essential.
Take Ran-OD Tablet 10's with or without food as directed by your doctor.
Yes, Ranitidine was once considered an effective medication for treating conditions like heartburn, acid reflux, and ulcers. It works by reducing the amount of acid produced by the stomach.
To ensure safe medication use, always follow your doctor's instructions, read medication labels carefully, take medications at the right time, inform your doctor about allergies or medical conditions, report any side effects, store medications properly, and dispose of them safely. Avoid self-medication, combining medications without consulting your doctor, stopping medications suddenly, sharing medications, and taking expired medications. If you have any questions or concerns, consult with your healthcare provider.
It is best to avoid alcohol while taking this medicine. Alcohol can irritate your stomach lining, increase acid production, and make your acid reflux symptoms worse. Talk to your doctor for advice.
Ranitidine and omeprazole are both used to treat heartburn, ulcers, and other gastrointestinal issues. Still, they have different mechanisms of action and are in different drug classes.
Historically, Ran-OD Tablet 10's was sometimes used during pregnancy when considered necessary by a healthcare professional. However, because Ran-OD Tablet 10's has been withdrawn from many markets, including India, it is no longer routinely used. If you are pregnant or planning to become pregnant, speak with your doctor, who can recommend a currently approved and appropriate alternative if acid-relief treatment is needed.
While it is not common, some people may experience mild drowsiness or sleepiness while taking this medicine. Avoid driving or operating machinery until you know how it affects you, and talk to your doctor if this side effect persists.
If your heartburn, reflux, or stomach symptoms do not improve after two weeks, or if they become worse, seek medical attention promptly. Persistent symptoms may indicate a more serious underlying condition, such as severe reflux disease, peptic ulcer disease, Helicobacter pylori infection, or, in rare cases, a more serious gastrointestinal disorder. Because Ran-OD Tablet 10's is no longer routinely available in many countries, your doctor may recommend a safer and more appropriate alternative treatment.
This medicine is primarily filtered out of your system by your kidneys. If you have kidney problems, your doctor may need to adjust your dose to prevent the medicine from building up in your body. Talk to your doctor or pharmacist if you have concerns about your kidney health.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

No 9,Tsd Nagar,1St Main Road,Arumbakkam, Chennai-600106
Other Info - RAN0337

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