apollo
0
  1. Home
  2. Medicine
  3. RCINEX R CIN + INH 450MG CAPSULE

Not for online sale
coupon
coupon
coupon
Extra 15% Off with Bank Offers
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
RCINEX R CIN + INH 450MG CAPSULE is used to treat and prevent tuberculosis. It contains Rifampicin, and Isoniazid, which works by killing the bacteria causing TB (tuberculosis). In some cases, you may experience certain common side effects, such as drowsiness, dizziness, headache, weakness, muscle pain, heartburn, diarrhoea, gas, and numbness or tingling sensation. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
Read more

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

Oral

Expires on or after :

Return Policy :

Not Returnable

About RCINEX R CIN + INH 450MG CAPSULE

RCINEX R CIN + INH 450MG CAPSULE is used to treat and prevent tuberculosis. Tuberculosis is an infectious disease that mainly affects the lungs, but it can also spread to other body parts such as the kidneys, brain, spine, and bone marrow.

RCINEX R CIN + INH 450MG CAPSULE is a combination of two anti-tuberculosis drugs Rifampicin, and Isoniazid. Rifampicin inhibits DNA-dependent RNA polymerase activity in the bacteria. Isoniazid inhibits the biosynthesis of mycolic acid, which is the major component of the cell wall. Together, RCINEX R CIN + INH 450MG CAPSULE kills Mycobacterium tuberculosis, which causes TB (tuberculosis).

In some cases, you may experience certain common side effects, such as drowsiness, dizziness, headache, weakness, muscle pain, heartburn, diarrhoea, gas, and numbness or tingling sensation. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Consult your doctor before taking RCINEX R CIN + INH 450MG CAPSULE if you are pregnant or planning for pregnancy. Avoid breastfeeding while taking RCINEX R CIN + INH 450MG CAPSULE as it passes into breast milk. RCINEX R CIN + INH 450MG CAPSULE may cause dizziness, and vision problems, so drive only if you are alert. Avoid alcohol consumption while taking RCINEX R CIN + INH 450MG CAPSULE as it could lead to increased drowsiness, dizziness and liver damage.

Uses of RCINEX R CIN + INH 450MG CAPSULE

RCINEX R CIN + INH 450MG CAPSULE is used in the treatment of tuberculosis (TB). The detailed uses of RCINEX R CIN + INH 450MG CAPSULE are as follows:

  • Treats active tuberculosis: RCINEX R CIN + INH 450MG CAPSULE works by killing the bacteria that cause TB, helping to clear the infection from the lungs and other affected organs.
  • Prevents spread and recurrence: RCINEX R CIN + INH 450MG CAPSULE is also used to prevent TB from coming back or spreading to others, especially in people at high risk.

Have a query?

Directions for Use

  • RCINEX R CIN + INH 450MG CAPSULE should be taken on an empty stomach, at least 30 minutes before or 2 hours after a meal.
  • It is usually taken once daily or as prescribed by your doctor.
  • Swallow RCINEX R CIN + INH 450MG CAPSULE as a whole with a glass of water.
  • Do not crush or chew this medication.

Key Benefits

RCINEX R CIN + INH 450MG CAPSULE is a combination of two anti-tuberculosis drugs, Rifampicin, and Isoniazid. Rifampicin inhibits DNA-dependent RNA polymerase activity in the bacteria. Isoniazid inhibits the biosynthesis of mycolic acid, which is the major component of the cell wall. Together, RCINEX R CIN + INH 450MG CAPSULE kills Mycobacterium tuberculosis, which causes TB (tuberculosis).

How RCINEX R CIN + INH 450MG CAPSULE Works

RCINEX R CIN + INH 450MG CAPSULE is a combination of two anti-tuberculosis drugs Rifampicin, and Isoniazid. Rifampicin inhibits DNA-dependent RNA polymerase activity in the bacteria. Isoniazid inhibits the biosynthesis of mycolic acid, which is the major component of the cell wall. Together, RCINEX R CIN + INH 450MG CAPSULE kills Mycobacterium tuberculosis, which causes TB (tuberculosis).

Storage

Store in a cool and dry place away from sunlight
Side effects of Rcinex R Cin + Inh 450mg Capsule
  • Change positions or take a break from activity to relieve symptoms.
  • Avoid postures that put a lot of pressure on just one area of the body.
  • If you have vitamin deficiency, take supplements or change your diet.
  • Exercise regularly like cycling, walking or swimming.
  • Avoid sitting with your legs crossed.
  • Clench and unclench your fists and wiggle your toes.
  • Massage the affected area.
  • High levels of liver enzymes need immediate medical attention.
  • Watch your diet and consume low-fat foods, like green leafy vegetables, fish, whole grains, nuts, etc.
  • Regularly do strengthening exercises to control your cholesterol levels.
  • Avoid drinking alcohol as it can affect your liver.
  • Focus on losing weight as it can help control cholesterol and maintain liver enzymes.
  • Practice yoga and meditation to improve liver functioning and overall health.
Managing Medication-Triggered Flushing (Reddening of the skin): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
  • Avoid rubbing your eyes, which can exacerbate the issue.
  • Lubricate your eyes using artificial tears or eye drops.
  • Wear sunglasses while you are out in the sun to protect your eyes from sun and wind.
  • Avoid irritants like smoke, dust, and strong chemicals.
  • Get enough rest and sleep to help your eyes recover.
  • Inform your doctor about changes in saliva levels. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.

What if I have taken an overdose of RCINEX R CIN + INH 450MG CAPSULE

Do not take more than the prescribed dose of RCINEX R CIN + INH 450MG CAPSULE as it may cause overdose. The symptoms of overdose include stomach pain, nausea, vomiting, headache, itching, tiredness, dizziness, lightheadedness, drowsiness, fainting, blurred vision, or hallucinations. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take RCINEX R CIN + INH 450MG CAPSULE if you are allergic to any of its contents; if you have jaundice, or if you are taking HIV medicines (saquinavir or ritonavir). Before starting RCINEX R CIN + INH 450MG CAPSULE, please inform your doctor if you have diabetes, epilepsy, gout, mental health problems, HIV infection, malnutrition, peripheral neuropathy, porphyria, bleeding problems, kidney or liver problems. Consult your doctor before taking RCINEX R CIN + INH 450MG CAPSULE if you are pregnant or planning for pregnancy. Avoid breastfeeding while taking RCINEX R CIN + INH 450MG CAPSULE as it passes into breast milk. RCINEX R CIN + INH 450MG CAPSULE may cause dizziness, and drowsiness, so drive only if you are alert. Avoid alcohol consumption while taking RCINEX R CIN + INH 450MG CAPSULE as it could lead to increased drowsiness, dizziness and liver damage.

Drug-Drug Interactions

verifiedApollotooltip
RifampicinSaquinavir
Critical

Drug-Drug Interactions

Login/Sign Up

RifampicinSaquinavir
Critical
How does the drug interact with Rcinex R Cin + Inh 450mg Capsule:
Taking saquinavir with Rcinex R Cin + Inh 450mg Capsule can increase the risk or severity of side effects.

How to manage the interaction:
Although there is an interaction between pyrazinamide and Rcinex R Cin + Inh 450mg Capsule, they can be taken together if prescribed by a doctor. However, if you experience fever, stomach pain, less desire to eat, nausea, yellowing of the skin or eyes, or dark urine, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Rcinex R Cin + Inh 450mg Capsule:
When ranolazine is taken with Rcinex R Cin + Inh 450mg Capsule, it can reduce the blood levels and effects of ranolazine.

How to manage the interaction:
Although there is an interaction between ranolazine and Rcinex R Cin + Inh 450mg Capsule, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Rcinex R Cin + Inh 450mg Capsule:
Taking pirfenidone with Rcinex R Cin + Inh 450mg Capsule can reduce the levels and effects of pirfenidone

How to manage the interaction:
Although there is an interaction between pirfenidone and Rcinex R Cin + Inh 450mg Capsule, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Rcinex R Cin + Inh 450mg Capsule:
Taking darunavir with Rcinex R Cin + Inh 450mg Capsule can decrease the blood levels of darunavir, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between darunavir and Rcinex R Cin + Inh 450mg Capsule, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Rcinex R Cin + Inh 450mg Capsule:
When Indinavir is taken with Rcinex R Cin + Inh 450mg Capsule, it can reduce the blood levels and effects of Indinavir.

How to manage the interaction:
Although there is an interaction between indinavir and Rcinex R Cin + Inh 450mg Capsule, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Rcinex R Cin + Inh 450mg Capsule:
Taking Voriconazole with Rcinex R Cin + Inh 450mg Capsule can increase blood level of Voriconazole.

How to manage the interaction:
Although there is an interaction between Voriconazole with Rcinex R Cin + Inh 450mg Capsule, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Rcinex R Cin + Inh 450mg Capsule:
When Lovastatin is taken with Rcinex R Cin + Inh 450mg Capsule, can increase the risk of myopathy (muscles problems), including rhabdomyolysis (a condition that causes your muscles to break down, which leads to muscle death).

How to manage the interaction:
Taking Rcinex R Cin + Inh 450mg Capsule with Lovastatin is not recommended but can be taken if a doctor has prescribed it.
IsoniazidLomitapide
Critical
How does the drug interact with Rcinex R Cin + Inh 450mg Capsule:
When Lomitapide is taken with Rcinex R Cin + Inh 450mg Capsule, Rcinex R Cin + Inh 450mg Capsule may increase the blood levels of lomitapide which leads to side effects.

How to manage the interaction:
Taking Rcinex R Cin + Inh 450mg Capsule with Lomitapide is not recommended but can be taken if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, exhaustion, nausea, vomiting, dark urine, light stools, and skin or eye yellowing, decreased hunger, consult the doctor.
How does the drug interact with Rcinex R Cin + Inh 450mg Capsule:
When Rcinex R Cin + Inh 450mg Capsule is taken with Regorafenib, it can increase the levels of Regorafenib leading to side effects.

How to manage the interaction:
Taking Regorafenib with Rcinex R Cin + Inh 450mg Capsule is not recommended, it taken can be taken if prescribed by the doctor.
How does the drug interact with Rcinex R Cin + Inh 450mg Capsule:
Taking dolutegravir with Rcinex R Cin + Inh 450mg Capsule can decrease the blood levels of dolutegravir, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between dolutegravir and Rcinex R Cin + Inh 450mg Capsule, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
ISONIAZID-300MG+RIFAMPICIN-450MGTyramine-containing food
Moderate

Drug-Food Interactions

Login/Sign Up

ISONIAZID-300MG+RIFAMPICIN-450MGTyramine-containing food
Moderate
Common Foods to Avoid:
Pepperoni, Miso Soup, Natto, Ricotta, Salami, Shoyu, Shrimp, Stilton Cheese, Swiss Cheese, Tamari, Tempeh, Fish, Farm Cheese, Fava Beans, Fermented Seafood, Fermented Tofu, Gorgonzola Cheese, Chicken Liver, Chocolates, Cottage Cheese, Cream Cheese, Dried Sausage, Dry-Type Summer Sausages, Cheddar Cheese, Cashews, Camembert, Beef Liver, American Cheese, Almonds, Avocado

How to manage the interaction:
Coadministration of Rcinex R Cin + Inh 450mg Capsule with foods containing tyramine increases the risk of side effects such as headache, sweating, diarrhea, nausea, vomiting, fast heartbeats, difficulty breathing, and low blood pressure. Avoid foods containing tyramine while being treated with Rcinex R Cin + Inh 450mg Capsule , as it can lead to side effects.

Diet & Lifestyle Advise

  • Pineapple juice might help soothe the symptoms of cough and cold. It also has anti-inflammatory and mucolytic properties.

  • Foods rich in vitamin C such as kiwi, broccoli, and bell pepper helps in improving the immune system. 

  • Avoid processed and fried foods.

  • Warm ginger tea or warm soup can help in providing relief from cough.

  • Avoid foods and drinks containing histamine or tyramine such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer.

  • Quit smoking and avoid alcohol consumption.

Habit Forming

No

Therapeutic Class

[ANTI- TUBERCULOSIS]

bannner image

Alcohol

Safe if prescribed

Avoid alcohol consumption while taking RCINEX R CIN + INH 450MG CAPSULE as it could lead to increased drowsiness, dizziness and liver damage.

bannner image

Pregnancy

Consult your doctor

Please consult your doctor if you are pregnant, your doctor will prescribe RCINEX R CIN + INH 450MG CAPSULE only if the benefits outweigh the risks.

bannner image

Breast Feeding

Consult your doctor

RCINEX R CIN + INH 450MG CAPSULE passes into breast milk. Do not breastfeed while taking RCINEX R CIN + INH 450MG CAPSULE.

bannner image

Driving

Safe if prescribed

RCINEX R CIN + INH 450MG CAPSULE may cause dizziness, drowsiness, numbness and tingling sensation in hands and feet. Do not drive or operate machinery if you experience these symptoms.

bannner image

Liver

Consult your doctor

Dose adjustment may be needed. Please consult your doctor before taking RCINEX R CIN + INH 450MG CAPSULE if you have liver impairment/liver disease.

bannner image

Kidney

Consult your doctor

Dose adjustment may be needed. Please consult your doctor if you have any concerns regarding this or if you have kidney impairment/kidney disease before taking RCINEX R CIN + INH 450MG CAPSULE.

bannner image

Children

Safe if prescribed

Please consult your doctor. Your doctor may suggest suitable dose and dosage form based on your child's age, body weight and medical condition. Kid tablets could be used in children if prescribed by the doctor.

bannner image

Heart

RCINEX R CIN + INH 450MG CAPSULE can be used in heart patients if prescribed by the physician. Please consult your physician if you have any concerns.

bannner image

Geriatrics

Consult your doctor

RCINEX R CIN + INH 450MG CAPSULE is not recommended for use in elderly patients as it can lead to side effects.

FAQs

RCINEX R CIN + INH 450MG CAPSULE belongs to the group of medicines called anti-tuberculosis drugs primarily used to treat and prevent tuberculosis.

RCINEX R CIN + INH 450MG CAPSULE is a combination of two anti-tuberculosis drugs, namely: Rifampicin, and Isoniazid. Rifampicin inhibits DNA-dependent RNA polymerase activity in the bacteria. Isoniazid inhibits the biosynthesis of mycolic acid, which is the major component of the cell wall. Together, RCINEX R CIN + INH 450MG CAPSULE kills Mycobacterium tuberculosis which causes TB (tuberculosis).

Do not stop taking RCINEX R CIN + INH 450MG CAPSULE despite symptomatic relief. To treat your condition effectually, continue taking RCINEX R CIN + INH 450MG CAPSULE for as long as it has been prescribed for you.

Do not take RCINEX R CIN + INH 450MG CAPSULE along with antacids as it might decrease the effectiveness of RCINEX R CIN + INH 450MG CAPSULE. Maintain a minimum gap of 1hour between both.

Consult your doctor before taking RCINEX R CIN + INH 450MG CAPSULE with other medicines. Medicines used to treat TB such as PAS (P-amino salicylic acid) and cycloserine should be taken 8hours apart from RCINEX R CIN + INH 450MG CAPSULE.

RCINEX R CIN + INH 450MG CAPSULE contains isoniazid which might interact with foods and drinks containing histamine or tyramine such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer. Avoid these foods while taking RCINEX R CIN + INH 450MG CAPSULE.

RCINEX R CIN + INH 450MG CAPSULE might decrease the effectiveness of oral contraceptives (birth control pills). This could lead to an unplanned pregnancy. Instead, use a reliable barrier method of contraception such as condoms or the coil while taking RCINEX R CIN + INH 450MG CAPSULE. Consult your doctor if you have any concerns regarding this; your doctor may suggest an alternate method of contraception.

RCINEX R CIN + INH 450MG CAPSULE may cause discolouration of teeth, sweat, urine, sputum (phlegm), saliva, or tears. The colour in tears may last for some time even after you stop taking RCINEX R CIN + INH 450MG CAPSULE. Do not worry as it is a common side-effect of RCINEX R CIN + INH 450MG CAPSULE.

Yes, RCINEX R CIN + INH 450MG CAPSULE might permanently stain soft contact lenses. Use spectacles and avoid wearing contact lens while taking RCINEX R CIN + INH 450MG CAPSULE.

RCINEX R CIN + INH 450MG CAPSULE may affect test results of some blood tests such as tests for folate, vitamin B12, and liver function. Inform the person doing the tests that you are taking RCINEX R CIN + INH 450MG CAPSULE.

Yes, RCINEX R CIN + INH 450MG CAPSULE may cause liver problems, especially in people who are 35 and older. Consult your doctor if you notice symptoms such as yellowing of eyes or skin, dark urine, pale stools, weakness, loss of appetite, nausea or vomiting. Your doctor may advise you to get regular liver tests while taking RCINEX R CIN + INH 450MG CAPSULE to check how your liver is functioning.

Yes, RCINEX R CIN + INH 450MG CAPSULE can cause temporary discoloration of urine and sweat. This is a common and harmless side effect.

RCINEX R CIN + INH 450MG CAPSULE is a combination of two anti-tuberculosis drugs, Rifampicin and Isoniazid. It is used in the treatment of Tuberculosis.

Before using RCINEX R CIN + INH 450MG CAPSULE, you should learn about its use, side effects, and limitations.

If you forget a dose of RCINEX R CIN + INH 450MG CAPSULE, take it immediately when you remember. However, if your next dose is near, skip the missed dose and continue with your regular schedule. Never double dose to make up for a missed dose, as this may increase side effects.

The best time to take RCINEX R CIN + INH 450MG CAPSULE is 30 minutes before food or 2 hours after food. This helps your body absorb the medication more effectively.

Store RCINEX R CIN + INH 450MG CAPSULE in a cool, dry place out of sunlight and children's reach. Check the expiration date regularly. To dispose of it, place it in a plastic bag and throw it away in household trash. Never flush it down the toilet or sink.

You should avoid alcohol while taking RCINEX R CIN + INH 450MG CAPSULE strictly to ensure safety and efficacy, as it can increase the risk of liver damage when combined with medications like Isoniazid and Rifampicin.

Common side effects of RCINEX R CIN + INH 450MG CAPSULE may include drowsiness, dizziness, headache, weakness, muscle pain, heartburn, diarrhea, gas, and numbness. However, these symptoms vanish as your body adjusts to the medication. If these symptoms become worse, please consult a doctor for relief.

Before using this medication, you should inform your doctor about your medical history, including any ongoing medicines, to avoid potential interactions and minimize side effects.

Taking more than the recommended dosage does not provide additional relief and can increase the risk of adverse effects.

RCINEX R CIN + INH 450MG CAPSULE is generally considered safe when used as prescribed by a doctor. However, like all medications, it can have side effects and potential interactions with other drugs. It's important to follow your doctor's instructions and inform them of any pre-existing and existing medical conditions or medication history to avoid negative complications.

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India Country of Origin: India
Other Info - RCI0006

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Author Details

Doctor imageWe provide you with authentic, trustworthy and relevant information

whatsapp Floating Button