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compositionComposition:ISONIAZID-300MG+RIFAMPICIN-450MG
prescription
Prescription Medicine
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RCINEX R CIN + INH 450MG CAPSULE is used to treat and prevent tuberculosis. It contains Rifampicin, and Isoniazid, which works by killing the bacteria causing TB (tuberculosis). In some cases, you may experience certain common side effects, such as drowsiness, dizziness, headache, weakness, muscle pain, heartburn, diarrhoea, gas, and numbness or tingling sensation. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

ISONIAZID-300MG+RIFAMPICIN-450MG

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About RCINEX R CIN + INH 450MG CAPSULE

RCINEX R CIN + INH 450MG CAPSULE is a prescription oral medicine used to treat active and latent tuberculosis infections. It combines two active antibiotics that work together to eliminate the bacteria causing the infection. Taking this medicine helps cure the infection and prevents it from spreading to others.

To work effectively, you must take RCINEX R CIN + INH 450MG CAPSULE consistently every day exactly as prescribed, even if you start feeling better. It should be taken on an empty stomach, either one hour before or two hours after a meal, with a full glass of water. Maintaining a balanced diet and getting plenty of rest are helpful lifestyle changes during your recovery.

While taking this medicine, you may notice mild side effects like your urine, sweat, or saliva turning an orange-red colour. However, if you experience more serious symptoms such as severe abdominal pain, persistent nausea, or yellowing of your skin and eyes, you must contact your doctor immediately.

Do not take this if you have severe liver damage, acute liver disease, or have previously had a severe allergic reaction to either of its active components. Talk to your doctor before starting RCINEX R CIN + INH 450MG CAPSULE if you have a history of liver problems, kidney disease, diabetes, or nerve pain.

This medicine can interact with alcohol, significantly raising the risk of serious liver damage, and can reduce the effectiveness of hormonal birth control. If you are pregnant, breastfeeding, or planning a pregnancy, talk to your doctor or pharmacist to discuss the risks and benefits before starting treatment.

Uses of RCINEX R CIN + INH 450MG CAPSULE

RCINEX R CIN + INH 450MG CAPSULE is used to treat active and latent tuberculosis infections. The detailed uses of RCINEX R CIN + INH 450MG CAPSULE are as follows:

  • Tuberculosis Treatment: RCINEX R CIN + INH 450MG CAPSULE is prescribed to treat active tuberculosis infections in the lungs and other parts of the body by killing the disease-causing bacteria.
  • Tuberculosis Prevention: It is used to prevent active tuberculosis from developing in individuals who have a latent (inactive) tuberculosis infection.
     

Key Benefits

RCINEX R CIN + INH 450MG CAPSULE helps treat tuberculosis by preventing the growth and spread of the bacteria responsible for the infection. By targeting the underlying cause of the disease, it supports recovery and helps improve symptoms over the course of treatment.

  • Helps Relieve Tuberculosis Symptoms: As the infection comes under control, symptoms such as persistent cough, chest discomfort, fever, night sweats, and fatigue gradually improve, helping you regain strength and overall well-being.
  • Supports Effective Tuberculosis Treatment: The combination of two anti-tuberculosis medicines works together to fight the infection more effectively, helping reduce the bacterial load and support successful treatment outcomes.
  • Simplifies Long-Term Treatment: By combining two medicines into a single oral treatment, RCINEX R CIN + INH 450MG CAPSULE reduces the number of tablets you need to take each day. This convenience can help improve treatment adherence and support completion of the full course of therapy.
     
Side effects of Rcinex R Cin + Inh 450mg Capsule
  • Change positions or take a break from activity to relieve symptoms.
  • Avoid postures that put a lot of pressure on just one area of the body.
  • If you have vitamin deficiency, take supplements or change your diet.
  • Exercise regularly like cycling, walking or swimming.
  • Avoid sitting with your legs crossed.
  • Clench and unclench your fists and wiggle your toes.
  • Massage the affected area.
  • High levels of liver enzymes need immediate medical attention.
  • Watch your diet and consume low-fat foods, like green leafy vegetables, fish, whole grains, nuts, etc.
  • Regularly do strengthening exercises to control your cholesterol levels.
  • Avoid drinking alcohol as it can affect your liver.
  • Focus on losing weight as it can help control cholesterol and maintain liver enzymes.
  • Practice yoga and meditation to improve liver functioning and overall health.
Managing Medication-Triggered Flushing (Reddening of the skin): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
  • Avoid rubbing your eyes, which can exacerbate the issue.
  • Lubricate your eyes using artificial tears or eye drops.
  • Wear sunglasses while you are out in the sun to protect your eyes from sun and wind.
  • Avoid irritants like smoke, dust, and strong chemicals.
  • Get enough rest and sleep to help your eyes recover.
  • Inform your doctor about changes in saliva levels. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.

Directions for Use

  • Take RCINEX R CIN + INH 450MG CAPSULE exactly as prescribed by your doctor. Do not change your dose or stop taking it without consulting them.
  • Swallow the tablet whole with a full glass of water. Do not crush, chew, or break it.
  • Take this medicine on an empty stomach, either 1 hour before or 2 hours after meals, to ensure the medicine is properly absorbed by your body.
  • Keep taking this medication for the full length of time prescribed by your doctor, even if your symptoms disappear after a few weeks.
     

How RCINEX R CIN + INH 450MG CAPSULE Works

RCINEX R CIN + INH 450MG CAPSULE is a combination medicine containing two active ingredients, rifampicin and isoniazid, which target the target bacteria in different ways to ensure the infection is thoroughly cleared. The first active ingredient, rifampicin, works by blocking a specific enzyme known as RNA polymerase, which the bacteria need to make proteins and reproduce. This effectively stops the bacteria from multiplying. The second active ingredient, isoniazid, targets the protective outer cell wall of the bacteria. It prevents the bacteria from building mycolic acid, a crucial component of their cell wall, causing the cell wall to break down and killing the bacteria.
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Alcohol

Unsafe

Avoid alcohol consumption while taking RCINEX R CIN + INH 450MG CAPSULE as it could lead to increased drowsiness, dizziness and liver damage.

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Pregnancy

Caution

Please consult your doctor if you are pregnant, your doctor will prescribe RCINEX R CIN + INH 450MG CAPSULE only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

RCINEX R CIN + INH 450MG CAPSULE passes into breast milk. Do not breastfeed while taking RCINEX R CIN + INH 450MG CAPSULE.

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Driving

Caution

RCINEX R CIN + INH 450MG CAPSULE may cause dizziness, drowsiness, numbness and tingling sensation in hands and feet. Do not drive or operate machinery if you experience these symptoms.

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Liver

Caution

Dose adjustment may be needed. Please consult your doctor before taking RCINEX R CIN + INH 450MG CAPSULE if you have liver impairment/liver disease.

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Kidney

Caution

Dose adjustment may be needed. Please consult your doctor if you have any concerns regarding this or if you have kidney impairment/kidney disease before taking RCINEX R CIN + INH 450MG CAPSULE.

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Children

Consult your doctor

Please consult your doctor. Your doctor may suggest suitable dose and dosage form based on your child's age, body weight and medical condition. Kid tablets could be used in children if prescribed by the doctor.

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Heart

Caution

RCINEX R CIN + INH 450MG CAPSULE can be used in heart patients if prescribed by the physician. Please consult your physician if you have any concerns.

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Geriatrics

Unsafe

RCINEX R CIN + INH 450MG CAPSULE is not recommended for use in elderly patients as it can lead to side effects.

What if I have taken an overdose of RCINEX R CIN + INH 450MG CAPSULE

Do not take more than the prescribed dose of RCINEX R CIN + INH 450MG CAPSULE as it may cause overdose. The symptoms of overdose include stomach pain, nausea, vomiting, headache, itching, tiredness, dizziness, lightheadedness, drowsiness, fainting, blurred vision, or hallucinations. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Avoid alcohol completely: Drinking alcohol while taking this medicine significantly increases the risk of serious liver damage.
  • Avoid certain foods: Do not eat foods high in tyramine and histamine, such as aged cheeses, red wine, soy sauce, yeast extracts, and certain fish like tuna or mackerel. Combining these foods with this medicine can trigger flushing, sweating, a rapid heartbeat, or headaches.
  • Take Vitamin B6 (pyridoxine) if recommended: Your doctor may advise taking a vitamin B6 supplement daily to help prevent nerve tingling or numbness caused by isoniazid.
  • Stay hydrated: Drink plenty of water throughout the day to help your kidneys filter the medication safely.
     

Health Queries

I have been experiencing chest pain for the past four months and suspect I might have tuberculosis. What diagnostic tests should I undergo to confirm this, and what is the standard medication used to treat TB?

Vikas Singh

Vikas Singh

M Pharmacy

Chest pain can stem from various causes, so a proper medical evaluation is essential. To diagnose TB, doctors typically recommend a chest X-ray, sputum tests to look for the bacteria, and a blood test (IGRA) or skin test. If diagnosed, TB is cured using a standard six-month course of daily oral antibiotics. This regimen combines four primary generic medications: Isoniazid, Rifampicin, Pyrazinamide, and Ethambutol. I strongly advise visiting a healthcare provider soon for a definitive diagnosis and a personalised care plan.

My lung fluid sample has tested positive for tuberculosis. What medications or treatment options are recommended for this condition?

Vikas Singh

Vikas Singh

M Pharmacy

Please be reassured that tuberculosis is highly treatable and completely curable. For TB in the lung fluid, the standard treatment is a highly effective course of antibiotics lasting six months. For the first two months, you will typically take four medications: isoniazid, rifampicin, pyrazinamide, and ethambutol. This is followed by a four-month phase where you continue taking just isoniazid and rifampicin. The most important step is to take these medications exactly as prescribed every single day, even after you start feeling better, to completely clear the infection. Your doctor will support you and monitor your progress throughout your recovery.
health query

Have a query?

How Soon It Starts Working

The time required for RCINEX R CIN + INH 450MG CAPSULE to start to work: The time required for RCINEX R CIN + INH 450MG CAPSULE to show its action is unknown. The time for which the effects of RCINEX R CIN + INH 450MG CAPSULE last: The duration of action for RCINEX R CIN + INH 450MG CAPSULE is unknown.

What if you forget to take RCINEX R CIN + INH 450MG CAPSULE

Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and follow your regular dosing schedule. Do not take a double dose to make up for your missed dose.

Storage

• Store RCINEX R CIN + INH 450MG CAPSULE at room temperature, ideally between 15°C and 30°C (59°F to 86°F), in a dry place. •Keep the medicine in its original container to protect it from direct light and moisture. Do not store it in the bathroom.

Drug Warnings

  • Expect your body fluids (urine, tears, sweat, saliva) to turn red-orange; this is a harmless side effect of the medicine.
  • Avoid wearing soft contact lenses during treatment, as they may become permanently stained by your tears.
  • Do not stop taking this medicine early, even if you feel completely better, to prevent the bacteria from becoming resistant to antibiotics.
  • Use a non-hormonal method of birth control (such as condoms), as RCINEX R CIN + INH 450MG CAPSULE can make hormonal contraceptives like birth control pills, patches, or implants less effective.
  • Attend all scheduled appointments for blood tests so your doctor can regularly monitor your liver function throughout your treatment.
     

Drug-Drug Interactions

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Before using RCINEX R CIN + INH 450MG CAPSULE, it is important to understand how it may interact with other medicines, foods, or existing health conditions.

Drug-Drug Interactions

  • Hormonal contraceptives: RCINEX R CIN + INH 450MG CAPSULE may reduce the effectiveness of certain hormonal contraceptives. Discuss appropriate contraceptive options with your doctor, who may recommend additional or alternative methods of birth control during treatment.
  • Blood thinners (e.g., warfarin): This medicine may reduce the effectiveness of anticoagulants, potentially affecting blood clotting control. Your doctor may need to monitor your clotting parameters and adjust treatment if necessary.
  • Anti-seizure medicines (e.g., phenytoin): Taking RCINEX R CIN + INH 450MG CAPSULE with certain anticonvulsants may alter the levels or effects of either medicine, potentially increasing the risk of side effects or affecting seizure control. Close monitoring may be required.
  • Antifungal medicines (e.g., ketoconazole): RCINEX R CIN + INH 450MG CAPSULE may reduce the absorption and effectiveness of certain antifungal medications, which could make fungal infections more difficult to treat.

Drug-Food Interactions

  • Foods high in tyramine or histamine (e.g., aged cheese, red wine, tuna): Consuming large amounts of these foods may increase the risk of symptoms such as flushing, itching, headache, palpitations, or a rapid heart rate in susceptible individuals.

Drug-Disease Interactions

  • Liver disease: Use RCINEX R CIN + INH 450MG CAPSULE with caution if you have liver impairment. The medicine may worsen underlying liver conditions or increase the risk of liver-related side effects. Your doctor may recommend regular liver function monitoring during treatment.
  • Diabetes: RCINEX R CIN + INH 450MG CAPSULE may affect blood glucose control, making blood sugar levels more difficult to manage. Patients with diabetes should monitor their blood sugar regularly and consult their doctor if significant changes occur.
  • Gout: This medicine may increase uric acid levels in the blood, which can trigger or worsen gout attacks in susceptible individuals. Patients with a history of gout should discuss appropriate monitoring and management with their healthcare provider.
     
Rifampicin + IsoniazidSaquinavir
Critical
Rifampicin + IsoniazidVoriconazole
Critical

Drug-Drug Interactions

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Rifampicin + IsoniazidSaquinavir
Critical
How does the drug interact with Rcinex R Cin + Inh 450mg Capsule:
Taking saquinavir with Rcinex R Cin + Inh 450mg Capsule can increase the risk or severity of side effects.

How to manage the interaction:
Although there is an interaction between pyrazinamide and Rcinex R Cin + Inh 450mg Capsule, they can be taken together if prescribed by a doctor. However, if you experience fever, stomach pain, less desire to eat, nausea, yellowing of the skin or eyes, or dark urine, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Rifampicin + IsoniazidVoriconazole
Critical
How does the drug interact with Rcinex R Cin + Inh 450mg Capsule:
Taking voriconazole with Rcinex R Cin + Inh 450mg Capsule can increase the risk of infections.

How to manage the interaction:
Although there is an interaction between voriconazole and Rcinex R Cin + Inh 450mg Capsule, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Rifampicin + IsoniazidRanolazine
Critical
How does the drug interact with Rcinex R Cin + Inh 450mg Capsule:
Taking ranolazine with Rcinex R Cin + Inh 450mg Capsule can reduce the blood levels and effects of ranolazine.

How to manage the interaction:
Although there is an interaction between ranolazine and Rcinex R Cin + Inh 450mg Capsule, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Rifampicin + IsoniazidIndinavir
Critical
How does the drug interact with Rcinex R Cin + Inh 450mg Capsule:
Taking indinavir with Rcinex R Cin + Inh 450mg Capsule can reduce the blood levels and effects of indinavir.

How to manage the interaction:
Although there is an interaction between indinavir and Rcinex R Cin + Inh 450mg Capsule, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Rifampicin + IsoniazidDarunavir
Critical
How does the drug interact with Rcinex R Cin + Inh 450mg Capsule:
Taking darunavir with Rcinex R Cin + Inh 450mg Capsule can decrease the blood levels of darunavir, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between darunavir and Rcinex R Cin + Inh 450mg Capsule, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Rifampicin + IsoniazidDeflazacort
Severe
How does the drug interact with Rcinex R Cin + Inh 450mg Capsule:
Taking deflazacort with Rcinex R Cin + Inh 450mg Capsule may reduce the blood levels and effects of deflazacort.

How to manage the interaction:
Although there is an interaction between deflazacort and Rcinex R Cin + Inh 450mg Capsule, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Rifampicin + IsoniazidTenofovir alafenamide
Severe
How does the drug interact with Rcinex R Cin + Inh 450mg Capsule:
Taking tenofovir alafenamide with Rcinex R Cin + Inh 450mg Capsule can reduce blood levels of tenofovir and reduce its effectiveness.

How to manage the interaction:
Although there is an interaction between Rcinex R Cin + Inh 450mg Capsule and tenofovir alafenamide, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Rifampicin + IsoniazidApremilast
Severe
How does the drug interact with Rcinex R Cin + Inh 450mg Capsule:
Taking apremilast with Rcinex R Cin + Inh 450mg Capsule can reduce blood levels and also increase the risk of side effects of Rcinex R Cin + Inh 450mg Capsule.

How to manage the interaction:
Although there is an interaction between Rcinex R Cin + Inh 450mg Capsule and apremilast, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Rifampicin + IsoniazidBCG vaccine
Severe
How does the drug interact with Rcinex R Cin + Inh 450mg Capsule:
Taking the BCG vaccine with Rcinex R Cin + Inh 450mg Capsule can increase the risk of side effects, which can lead to liver problems.

How to manage the interaction:
Although there is a possible interaction between Rcinex R Cin + Inh 450mg Capsule and BCG vaccine, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Rifampicin + IsoniazidTenofovir disoproxil
Severe
How does the drug interact with Rcinex R Cin + Inh 450mg Capsule:
Taking tenofovir disoproxil with Rcinex R Cin + Inh 450mg Capsule can reduce blood levels of tenofovir disoproxil and also reduce its effectiveness.

How to manage the interaction:
Although there is an interaction between Rcinex R Cin + Inh 450mg Capsule and tenofovir disoproxil, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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ISONIAZID-300MG+RIFAMPICIN-450MGTyramine-containing food
Moderate

Drug-Food Interactions

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ISONIAZID-300MG+RIFAMPICIN-450MGTyramine-containing food
Moderate
Common Foods to Avoid:
Pepperoni, Miso Soup, Natto, Ricotta, Salami, Shoyu, Shrimp, Stilton Cheese, Swiss Cheese, Tamari, Tempeh, Fish, Farm Cheese, Fava Beans, Fermented Seafood, Fermented Tofu, Gorgonzola Cheese, Chicken Liver, Chocolates, Cottage Cheese, Cream Cheese, Dried Sausage, Dry-Type Summer Sausages, Cheddar Cheese, Cashews, Camembert, Beef Liver, American Cheese, Almonds, Avocado

How to manage the interaction:
Coadministration of Rcinex R Cin + Inh 450mg Capsule with foods containing tyramine increases the risk of side effects such as headache, sweating, diarrhea, nausea, vomiting, fast heartbeats, difficulty breathing, and low blood pressure. Avoid foods containing tyramine while being treated with Rcinex R Cin + Inh 450mg Capsule , as it can lead to side effects.

Habit Forming

No

Therapeutic Class

[ANTI- TUBERCULOSIS]

FAQs

RCINEX R CIN + INH 450MG CAPSULE is a combination of two anti-tuberculosis medicines, Rifampicin and Isoniazid, used to treat and prevent tuberculosis (TB). These medicines work together to kill Mycobacterium tuberculosis, the bacteria that causes TB.
RCINEX R CIN + INH 450MG CAPSULE is a combination of two anti-tuberculosis drugs, namely: Rifampicin, and Isoniazid. Rifampicin inhibits DNA-dependent RNA polymerase activity in the bacteria. Isoniazid inhibits the biosynthesis of mycolic acid, which is the major component of the cell wall. Together, RCINEX R CIN + INH 450MG CAPSULE kills Mycobacterium tuberculosis which causes TB (tuberculosis).
No. Do not stop taking RCINEX R CIN + INH 450MG CAPSULE even if your symptoms, such as cough, improve. Stopping treatment early may allow the bacteria to survive, causing the infection to return and increasing the risk of drug-resistant tuberculosis. Complete the full course prescribed by your doctor.
Do not take RCINEX R CIN + INH 450MG CAPSULE along with antacids as it might decrease the effectiveness of RCINEX R CIN + INH 450MG CAPSULE. Maintain a minimum gap of 1hour between both.
Consult your doctor before taking RCINEX R CIN + INH 450MG CAPSULE with other medicines. Medicines used to treat TB such as PAS (P-amino salicylic acid) and cycloserine should be taken 8hours apart from RCINEX R CIN + INH 450MG CAPSULE.
RCINEX R CIN + INH 450MG CAPSULE contains isoniazid which might interact with foods and drinks containing histamine or tyramine such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer. Avoid these foods while taking RCINEX R CIN + INH 450MG CAPSULE.
Yes. RCINEX R CIN + INH 450MG CAPSULE may reduce the effectiveness of hormonal contraceptives, including birth control pills, patches, rings, and implants. Use a reliable non-hormonal method of contraception, such as condoms, while taking this medicine. Consult your doctor for advice on suitable contraceptive options.
RCINEX R CIN + INH 450MG CAPSULE may cause discolouration of teeth, sweat, urine, sputum (phlegm), saliva, or tears. The colour in tears may last for some time even after you stop taking RCINEX R CIN + INH 450MG CAPSULE. Do not worry as it is a common side-effect of RCINEX R CIN + INH 450MG CAPSULE.
Yes, RCINEX R CIN + INH 450MG CAPSULE might permanently stain soft contact lenses. Use spectacles and avoid wearing contact lens while taking RCINEX R CIN + INH 450MG CAPSULE.
RCINEX R CIN + INH 450MG CAPSULE may affect test results of some blood tests such as tests for folate, vitamin B12, and liver function. Inform the person doing the tests that you are taking RCINEX R CIN + INH 450MG CAPSULE.
Yes, RCINEX R CIN + INH 450MG CAPSULE may cause liver problems, particularly in adults over 35 years of age. Watch for symptoms such as yellowing of the skin or eyes, dark urine, pale stools, loss of appetite, severe nausea or vomiting, weakness, or persistent pain in the upper right side of the abdomen. Seek medical attention immediately if these symptoms occur. Your doctor may recommend regular liver function tests during treatment.
Before using RCINEX R CIN + INH 450MG CAPSULE, you should learn about its use, side effects, and limitations.
If you forget a dose of RCINEX R CIN + INH 450MG CAPSULE, take it immediately when you remember. However, if your next dose is near, skip the missed dose and continue with your regular schedule. Never double dose to make up for a missed dose, as this may increase side effects.
Take RCINEX R CIN + INH 450MG CAPSULE on an empty stomach, preferably 1 hour before food or 2 hours after food, to ensure optimal absorption and effectiveness.
Store RCINEX R CIN + INH 450MG CAPSULE in a cool, dry place out of sunlight and children's reach. Check the expiration date regularly. To dispose of it, place it in a plastic bag and throw it away in household trash. Never flush it down the toilet or sink.
You should avoid alcohol while taking RCINEX R CIN + INH 450MG CAPSULE strictly to ensure safety and efficacy, as it can increase the risk of liver damage when combined with medications like Isoniazid and Rifampicin.
Common side effects of RCINEX R CIN + INH 450MG CAPSULE may include drowsiness, dizziness, headache, weakness, muscle pain, heartburn, diarrhea, gas, and numbness. However, these symptoms vanish as your body adjusts to the medication. If these symptoms become worse, please consult a doctor for relief.
Before using this medication, you should inform your doctor about your medical history, including any ongoing medicines, to avoid potential interactions and minimize side effects.
Taking more than the recommended dosage does not provide additional relief and can increase the risk of adverse effects.
RCINEX R CIN + INH 450MG CAPSULE is generally considered safe when used as prescribed by a doctor. However, like all medications, it can have side effects and potential interactions with other drugs. It's important to follow your doctor's instructions and inform them of any pre-existing and existing medical conditions or medication history to avoid negative complications.
Tingling or numbness in your hands or feet can be a sign of nerve irritation. Your doctor may prescribe a vitamin B6 (pyridoxine) supplement to help prevent or treat this issue. Talk to your doctor right away if you notice these symptoms.
If you are pregnant or planning to become pregnant, you must discuss the benefits and potential risks of this medication with your healthcare provider. Treating tuberculosis is very important during pregnancy, but it requires careful medical supervision. Talk to your doctor for personalised advice.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Electronic Medicines Compendium (EMC). Pil.6124 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  2. Drugs.com Clinical Review Team. Isoniazid And Rifampin Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  3. Isoniazid/rifampicin. 1999. [Accessed on 10 Apr. 2019]Check here
  4. Isoniazid Isoniazid. 2015. [Accessed on 10 Apr. 2019]Check here
  5. Lee N, Nguyen H. Ethambutol. StatPearls [Internet]. NIH National Library of Medicine. National Center for Biotechnology Information. [Revised in October 2022] [Accessed on 04th March 2023]Check here
  6. Tuberculosis. National Health Service. [Accessed on 04th March 2023]Check here
  7. Isoniazid and Rifampicin combination for latent tuberculosis. [Accessed on 02 Jun. 2026]Check here

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India Country of Origin: India
Other Info - RCI0006
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