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compositionComposition:REGORAFENIB-40MG
prescription
Prescription Medicine
info
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Regoside 40 mg Tablet 28's is used to treat colorectal carcinoma. It contains Regorafenib as an active ingredient, which belongs to the class of medicines known as kinase inhibitors. It works by inhibiting the action of an enzyme (tyrosine kinase) and thus stops the abnormal growth of cancer cells. This medicine is not recommended for use in pregnant and breastfeeding mothers due to embryo-fetal toxicity.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

REGORAFENIB-40MG

Manufacturer/Marketer :

Lucien Life Sciences

Consume Type :

Oral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Regoside 40 mg Tablet 28's

Regoside 40 mg Tablet 28's is a prescription medicine used to treat adults with certain types of advanced cancers of the colon, rectum, stomach, and liver. It is typically prescribed after other standard treatments have already been tried. This medicine helps manage the growth and spread of these specific tumours.

To get the best results, you must take Regoside 40 mg Tablet 28's consistently at the same time each day exactly as your doctor instructs. It is taken as a daily dose for a specific number of weeks followed by a break period. Always take your dose after a low-fat meal, such as a light breakfast, to help your body absorb the medicine properly.

While taking this medicine, you may experience common side effects such as fatigue, diarrhoea, or a specific skin reaction on your hands and feet. However, you should contact your doctor immediately if you develop signs of serious issues, including severe bleeding, unusual bruising, or persistent stomach pain.

Before starting treatment, let your doctor know if you have high blood pressure, heart problems, or upcoming surgeries. Do not take this medicine if you have severe liver disease or are currently suffering from active, severe bleeding.

Certain prescription medications, herbal supplements, and even grapefruit juice can change how this medicine works, potentially causing dangerous side effects or reducing its effectiveness. If you are pregnant, planning to become pregnant, or breastfeeding, you must avoid taking this medicine because it can harm an unborn baby.

Uses of Regoside 40 mg Tablet 28's

Regoside 40 mg Tablet 28's is used to treat adults with certain types of advanced cancers of the colon, rectum, stomach, and liver. The detailed uses of Regoside 40 mg Tablet 28's are as follows:

  • Colorectal cancer: Used for advanced colon or rectal cancer that has spread to other parts of the body and has been treated with other chemotherapy medicines.
  • Gastrointestinal stromal tumours (GIST): Used for a rare type of stomach or bowel cancer that cannot be removed with surgery or has spread, after other treatments have stopped working.
  • Liver cancer: Used for people with advanced liver cancer who have been previously treated with another specific cancer medicine.

Key Benefits

Regoside 40 mg Tablet 28's helps treat certain advanced cancers by slowing the growth and spread of cancer cells. When used as prescribed, it helps control disease progression, supports ongoing cancer management, and may improve overall treatment outcomes in patients whose cancer has not responded to standard therapies.

  • Slows Cancer Progression: By blocking pathways that promote tumour growth and the formation of new blood vessels, this medicine helps slow or temporarily stop the progression of advanced cancers.
  • Helps Control Advanced Disease: This medicine provides an important treatment option for patients whose cancer has progressed despite previous therapies, helping to stabilise the disease and support continued cancer management.
  • Supports Quality of Life: By helping keep the cancer under control, this medicine may reduce disease-related symptoms, maintain physical functioning, and provide more stable periods during treatment.

Directions for Use

  • Take Regoside 40 mg Tablet 28's after a low-fat meal for best results.
  • Regoside 40 mg Tablet 28's should be taken once daily for the first 21 days of each 28-day cycle or as advised by your doctor.
  • Swallow the medicine as a whole with a glass of water.
  • Do not break, chew or crush Regoside 40 mg Tablet 28's.

How Regoside 40 mg Tablet 28's Works

Regoside 40 mg Tablet 28's contains regorafenib, which is a type of medicine known as a kinase inhibitor. It works by blocking several proteins (called kinases) that are found on the surface of both cancer cells and nearby blood vessel cells. These proteins act like switches that tell cancer cells to grow, divide, and multiply. By blocking these switches, the medicine helps stop the cancer cells from multiplying. Additionally, it cuts off the signal that allows new blood vessels to grow toward the tumour, effectively starving the tumour of the oxygen and nutrients it needs to survive.
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Alcohol

Unsafe

Avoid alcohol consumption while taking Regoside 40 mg Tablet 28's.

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Pregnancy

Unsafe

Regoside 40 mg Tablet 28's is not recommended for use in pregnancy as it may cause embryo-fetal toxicity and harm your foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before taking Regoside 40 mg Tablet 28's. You should not become pregnant while you are taking Regoside 40 mg Tablet 28's and for at least two weeks after your treatment. Using effective birth control methods while on treatment with Regoside 40 mg Tablet 28's is suggested.

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Breast Feeding

Unsafe

Regoside 40 mg Tablet 28's should not be taken if you are breastfeeding as it passes into breast milk and may harm your infant.

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Driving

Unsafe

Regoside 40 mg Tablet 28's may cause dizziness in some patients. Hence, do not drive, operate machinery, or engage in any activity that needs concentration until you are confident that you can do so safely while you are on treatment with Regoside 40 mg Tablet 28's.

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Liver

Caution

If you have a pre-existing or a history of liver problems, tell your doctor before taking this medicine. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

If you have a pre-existing or a history of kidney diseases, inform your doctor before taking Regoside 40 mg Tablet 28's. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Regoside 40 mg Tablet 28's is not recommended for use in children below 18 years of age as the safety and efficacy is not established.

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Heart

Consult your doctor

Please consult your doctor before receiving Regoside 40 mg Tablet 28's if you have pre-existing heart problems. Your doctor will prescribe Regoside 40 mg Tablet 28's if the benefits outweigh the risks.

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Geriatrics

Caution

Regoside 40 mg Tablet 28's should be used with caution in geriatric patients. Therefore, please consult your doctor before giving Regoside 40 mg Tablet 28's to elderly individuals.

What if I have taken an overdose of Regoside 40 mg Tablet 28's

If you accidentally take more than your prescribed dose, seek emergency medical care or contact a nearby hospital immediately.

Diet & Lifestyle Advise

  • Eat a low-fat breakfast before your dose to ensure the medicine is absorbed safely and effectively.
  • Avoid drinking grapefruit juice or eating grapefruit while on this medicine, as it can dangerously increase the drug levels in your body.
  • Moisturise your hands and feet regularly with a thick cream, and wear loose, comfortable socks and shoes to help prevent skin cracking and blistering.
  • Avoid exposing your hands and feet to very hot water or friction (like heavy scrubbing or intense physical activities) during the first few weeks of treatment.
  • Monitor your blood pressure daily at home, keeping a log to share with your doctor.
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How Soon It Starts Working

The time required for Regoside 40 mg Tablet 28's to start to work: The time required for Regoside 40 mg Tablet 28's to show its action is not clinically established. The time for which the effects of Regoside 40 mg Tablet 28's last: The duration of action for Regoside 40 mg Tablet 28's is not clinically established.

What if you forget to take Regoside 40 mg Tablet 28's

If you miss a dose, take it as soon as you remember on the same day. If you do not realise until the next day, skip the missed dose entirely and take your next dose at your regularly scheduled time. Do not take two doses at once to make up for a missed dose.

Storage

•Store Regoside 40 mg Tablet 28's at room temperature between 20°C to 25°C (68°F to 77°F) in its original container.

Drug Warnings

  • Write the date you first open the bottle directly on the label so you know when to safely discard any remaining tablets.
  • Always check the appearance of your tablets; do not use them if they appear damaged or altered.
  • Use a reliable form of birth control during treatment and for at least 2 months after your final dose to prevent pregnancy.
  • Notify your surgical team or dentist that you are taking this medicine, as you must stop taking it at least 2 weeks before any planned surgery or dental procedure to ensure proper wound healing.
  • Attend all scheduled blood work appointments so your healthcare provider can closely monitor your liver function and blood counts.

verifiedApollotooltip
  • Strong Antibiotics and Antifungal Medicines: Certain antibiotics, such as clarithromycin, and antifungal medicines, such as ketoconazole, can increase the levels of Regoside 40 mg Tablet 28's in your bloodstream, raising the risk of side effects. Your doctor may recommend dose adjustments or closer monitoring during treatment.
  • Medicines for Seizures or Tuberculosis: Medicines used to treat seizures, such as carbamazepine, and tuberculosis treatments, such as rifampin, can speed up the breakdown of Regoside 40 mg Tablet 28's, reducing its effectiveness. Inform your doctor if you are taking these medicines so your treatment can be adjusted if necessary.

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verifiedApollotooltip
  • Grapefruit and Grapefruit Juice: Do not consume grapefruit or grapefruit juice while taking Regoside 40 mg Tablet 28's, as they can slow the breakdown of the medicine, leading to excessively high levels in your bloodstream and increasing the risk of side effects.
  • High-Fat Foods: Avoid taking Regoside 40 mg Tablet 28's with high-fat meals, as they can significantly alter the absorption of the medicine and affect how well it works. Follow your doctor's instructions regarding meal timing.

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTINEOPLASTIC]

FAQs

Regoside 40 mg Tablet 28's is used to treat Colorectal Cancer.
Regoside 40 mg Tablet 28's contains Regorafenib, which works by stopping the action of a tyrosine kinase enzyme that causes the multiplication of cancerous cells.
Regoside 40 mg Tablet 28's is safe to be taken by a diabetic person. However, take Regoside 40 mg Tablet 28's only after consulting with a doctor, as they may adjust the dosing according to your condition.
You should know that this medicine may reduce fertility in both men and women. Discuss the risks of taking an irinotecan injection with your doctor.
Yes, Regoside 40 mg Tablet 28's is a chemotherapy agent used in the treatment of colon and rectal cancer.
Regoside 40 mg Tablet 28's should be taken with a low-fat breakfast. Swallow it as a whole with a glass of water. Do not crush, break, or chew the medicine.
Yes, Regoside 40 mg Tablet 28's works by shrinking the tumours or stopping their growth. Thereby, it helps treat colorectal cancer.
Regoside 40 mg Tablet 28's may cause side effects such as diarrhoea, rash, tiredness, decreased appetite, nausea, weight loss, fatigue, stomach pain, loss of appetite, hoarseness, and dizziness. Consult the doctor if any of these side effects persist or worsen.
No, you should not take Regoside 40 mg Tablet 28's on an empty stomach. It must be taken with a low-fat meal, like a light breakfast containing less than 30% fat, to make sure it is absorbed correctly by your body. Talk to your doctor or pharmacist if you need examples of low-fat meals.
This medicine can cause serious liver damage in some patients. Your doctor will perform regular blood tests to check how well your liver is functioning, especially during the first few months of treatment. If you notice yellowing of your skin or dark urine, contact your doctor immediately. Talk to your doctor if you have any concerns about your liver.
No, you must swallow the tablets whole with a glass of water. Do not crush, chew, split, or break them, as this can affect how the medicine is absorbed and increase your risk of side effects. Talk to your doctor if you have trouble swallowing pills.
This medicine can cause a common side effect known as hand-foot skin reaction, which causes redness, pain, and peeling. Keep your skin moisturised, avoid hot water, and contact your doctor right away, as they may need to adjust your dose. Talk to your doctor for advice on managing skin changes.
No, this medicine can cause severe harm or birth defects to an unborn baby. Both men and women should use highly effective birth control during treatment and for at least 2 months after the final dose. Talk to your doctor immediately if you or your partner suspect a pregnancy.
Yes, this medicine can cause a significant increase in blood pressure, often within the first week of starting treatment. You should monitor your blood pressure regularly at home. Talk to your doctor if your blood pressure readings are higher than normal.
You should avoid or severely limit alcohol while taking this medicine. Alcohol can place extra stress on your liver, which is already at risk for damage during this treatment. Talk to your doctor for personalised advice regarding alcohol use.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

1st floor, 446/1, Sai krupa ventures, Lucien Life Sciences, Rd Number 20, Jubilee Hills, Hyderabad, Telangana 500033
Other Info - REG0312
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