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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Repace A Tablet

Repace A Tablet is a prescription tablet used to manage high blood pressure, also known as hypertension. By lowering high blood pressure, this medication helps protect your heart and blood vessels from long-term damage. It is commonly prescribed to help reduce the risk of serious cardiovascular events like strokes or heart attacks.

For the best results, you should take Repace A Tablet consistently once every day, preferably at the exact same time. You can take this medication with or without food, as it does not affect how the drug is absorbed. To support the medication's effectiveness, it is highly recommended to adopt heart-healthy diet and lifestyle habits, such as reducing salt intake and staying active.

While taking Repace A Tablet , some people may experience mild side effects like dizziness, headaches, or swelling in the lower legs. These are usually manageable, but you must consult your doctor immediately if you experience serious symptoms such as severe chest pain, fainting, or swelling of the face and throat.

Talk to your doctor before starting Repace A Tablet if you have a history of kidney disease, liver damage, or severe dehydration. Do not take this medicine if you are pregnant, as it can cause serious harm to an unborn baby. It is also not suitable for individuals who have had severe allergic reactions to similar blood pressure drugs.
 

This medication can interact with other substances, such as potassium supplements or alcohol, which can cause blood pressure to drop too low or potassium levels to rise. If you are breastfeeding, elderly, or have complex medical conditions, consult your doctor or pharmacist to ensure this medicine is safe for your specific situation.
 

Uses of Repace A Tablet

Repace A Tablet is commonly prescribed to manage high blood pressure and reduce the risk of cardiovascular complications associated with uncontrolled hypertension, including:

  • High Blood Pressure (Hypertension): Repace A Tablet helps lower elevated blood pressure, making it easier for your heart to pump blood throughout your body.
  • Reduction of Stroke and Heart Attack Risk: By maintaining your blood pressure within a healthy range, this medicine helps reduce the risk of cardiovascular complications such as strokes and heart attacks.
  • Kidney Protection in Selected Patients with Type 2 Diabetes: Because losartan belongs to a class of medicines called angiotensin receptor blockers (ARBs), it may help slow the progression of kidney damage in certain people with type 2 diabetes and kidney disease. Your doctor will determine whether this benefit applies to your individual situation.
     

Key Benefits

Repace A Tablet offers several benefits by providing effective blood pressure control and protecting vital organs from the long-term effects of hypertension, including:

Taking Repace A Tablet provides reliable, 24-hour protection against the hidden damage that high blood pressure can cause to your vital organs. Even though you may not feel any different on a daily basis, lowering your blood pressure reduces the strain on your kidneys, heart, and brain, helping you stay healthier for the long term.

  • Improved Cardiovascular Protection: Maintaining healthy blood pressure levels helps reduce the risk of heart attacks, strokes, and other cardiovascular complications.
  • Protection of Vital Organs: Long-term blood pressure control helps protect the kidneys, heart, brain, and blood vessels from damage caused by hypertension.
  • Convenient Once-Daily Therapy: Because Repace A Tablet combines two active ingredients into a single, daily tablet, it simplifies your treatment routine.
     

Instead of managing and taking multiple separate pills, this combination drug makes it much easier to stay consistent with your daily doses, leading to more stable and dependable blood pressure control. 

Side effects of Repace A Tablet
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • If you experience low blood sugar levels, inform your doctor. They will assess the severity and make recommendations for the next actions.
  • Your doctor will assess your symptoms, blood sugar levels, and overall health before recommending the best course of action, which may include treatment, lifestyle modifications, or prescription adjustments.
  • Follow your doctor's instructions carefully to manage the episode and adjust your treatment plan.
  • Make medication adjustments as recommended by your doctor to prevent future episodes.
  • Implement diet and lifestyle modifications as your doctor advises to manage low blood sugar levels.
  • Monitor your blood sugar levels closely for patterns and changes.
  • Track your progress by recording your blood sugar levels, food intake, and physical activity.
  • Seek further guidance from your doctor if symptoms persist or worsen so that your treatment plan can be revised.
  • Limit fruit intake to two servings a day, choose a low-potassium options like apples and strawberries.
  • Restrict starchy vegetables like potatoes and pumpkin to half a cup daily.
  • Avoid or limit foods like tomato products, high-bran cereals, and salty or sugary snacks.
  • Limit dairy products to 200g of yoghurt or 300ml of milk per day.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.

Directions for Use

To get the most benefit from Repace A Tablet , please follow these step-by-step instructions carefully:

  • Swallow the tablet whole with a full glass of water. Do not chew, crush, or split the tablet.
  • Take this medicine once daily, with or without food, as directed by your doctor.
  • Try to take your dose at the same time every day to keep a steady amount of the medication in your body.
  • Always follow your doctor's exact instructions regarding how to take this medicine, and do not stop taking it suddenly even if you feel completely fine.
     

How Repace A Tablet Works

Repace A Tablet contains losartan and amlodipine, which work together to lower high blood pressure and improve blood flow throughout the body. Losartan is an angiotensin II receptor blocker (ARB) that works by blocking the action of angiotensin II, a natural substance that causes blood vessels to narrow. By preventing this effect, losartan helps relax and widen the blood vessels, allowing blood to flow more easily and reducing blood pressure. Amlodipine is a calcium channel blocker that prevents calcium from entering the muscle cells of the heart and blood vessels. This helps the blood vessels relax and widen, further improving blood flow and reducing the workload on the heart. Together, these actions help lower blood pressure, improve circulation, reduce strain on the heart, and decrease the risk of complications associated with hypertension, such as heart attack, stroke, and kidney damage.
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Alcohol

Unsafe

It is unsafe to consume alcohol, since alcohol consumption with Repace A Tablet may increase the risk of low blood pressure and cause adverse effects such as dizziness, fainting, light-headedness, or headache.

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Pregnancy

Caution

Please consult your doctor before taking Repace A Tablet if you plan to become pregnant or are already pregnant. Your doctor will weigh the potential risks and benefits before prescribing Repace A Tablet .

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Breast Feeding

Caution

There is no evidence on how Repace A Tablet affects breastfeeding. Please consult your doctor before taking Repace A Tablet if you are breastfeeding.

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Driving

Caution

Repace A Tablet may cause side effects like dizziness, headaches, nausea or tiredness, which can affect your ability to concentrate and drive. Hence, it is recommended not to drive or operate machinery until you are mentally alert.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before taking Repace A Tablet . The dosage will be initiated in lower doses and will be further increased in patients with liver diseases.

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Kidney

Caution

Repace A Tablet consists of Losartan, which may affect kidney function. Hence, it is advised to seek a doctor's advice before starting Repace A Tablet if you have kidney problems.

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Children

Caution

It is not recommended for children below six years. However, for children above six years, give Repace A Tablet in doses as prescribed by a doctor.

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Heart

Caution

Repace A Tablet is often prescribed to patients with heart problems to treat hypertension. However, it must be taken strictly under medical supervision, as it can affect liver and kidney function and may interact with other heart medications.

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Geriatrics

Caution

Repace A Tablet should be taken with caution in geriatric patients. Please inform your doctor before using Repace A Tablet .

What if I have taken an overdose of Repace A Tablet

An overdose of Repace A Tablet may cause unpleasant side effects. If you suspect you have taken an overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Reduce dietary sodium: Lower your salt intake by avoiding processed foods and using herbs instead of salt to flavour meals, as sodium causes water retention and raises blood pressure.
  • Avoid potassium-rich salt substitutes: One of the active ingredients in Repace A Tablet can increase potassium levels in your blood. Consult your doctor before using potassium supplements or potassium-based salt alternatives.
  • Stay properly hydrated: Drink adequate fluids throughout the day. Dehydration combined with blood pressure medicine can lead to excessive lightheadedness or dizziness.
  • Maintain a moderate exercise routine: Aim for low-impact cardiovascular activities, like brisk walking or cycling, for 30 minutes on most days of the week, with your doctor's approval.
     

Have a query?

How Soon It Starts Working

The time required for Repace A Tablet to start to work: Repace A Tablet ideally shows its action within 4 to 8 hours after administration.

The time for which the effects of Repace A Tablet last: The effect of Repace A Tablet lasts for 24 hours.

What if you forget to take Repace A Tablet

If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and take the next dose at the scheduled time. Do not take a double dose.

Storage

•Store Repace A Tablet tablets at room temperature, ideally between 68°F and 77°F (20°C to 25°C). •Keep the tablets in their original packaging to protect them from light, heat, and moisture.

Drug Warnings

  • Monitor Blood Pressure Regularly: Measure and track your blood pressure regularly at home, keeping a simple log to review with your doctor.
  • Change Positions Slowly: Rise slowly and carefully from a sitting or lying position to help prevent dizziness or falls, particularly when starting treatment or after a dose adjustment.Use Caution When Driving: Avoid driving or performing activities that require alertness until you understand how this medicine affects you.
  • Inform Healthcare Providers: Inform any doctor, surgeon, or dentist that you are taking Repace A Tablet before undergoing surgery or dental procedures.
  • Report a Persistent Cough: Although a persistent dry cough is much more commonly associated with ACE inhibitor medicines (a different class of blood pressure medications), inform your doctor if you develop an ongoing cough while taking this medicine so the cause can be properly assessed.
     

Drug-Drug Interactions

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Drug-Drug Interactions


Repace A Tablet may interact with certain medications, potentially affecting its effectiveness or increasing the risk of side effects, including:

  • Taking Repace A Tablet alongside other blood pressure medications or water pills (diuretics) can cause your blood pressure to drop too low, resulting in severe dizziness.
  • Combining this medicine with potassium-sparing water pills, potassium supplements, or certain medications can lead to dangerously high potassium levels in your blood.
  • Nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or naproxen can make Repace A Tablet less effective at lowering blood pressure and can increase the risk of kidney damage.
    This medicine can increase the levels of lithium in your blood, raising the risk of lithium toxicity.

Drug-Food Interactions

Certain foods and beverages may affect the safety and effectiveness of Repace A Tablet . For example:

  • Avoid eating grapefruit or drinking grapefruit juice while taking Repace A Tablet , as it can increase the amount of the medication in your bloodstream and increase the risk of side effects like leg swelling or low blood pressure.
  • Limit or avoid alcohol consumption, as alcohol can amplify the blood-pressure-lowering effect of this medicine, causing dizziness or fainting.


Drug-Disease Interactions

Certain medical conditions may require special precautions when using Repace A Tablet , including:

  • Kidney Disease: If you have severe kidney problems, taking Repace A Tablet can further affect your kidney function, requiring regular blood tests.
  • Liver Damage: This medicine is processed by the liver. If you have liver disease, the drug can build up in your body, meaning you may require a lower starting dose.
  • Dehydration or Low Salt Levels: If you have recently experienced severe vomiting, diarrhoea, or excessive sweating, taking this medication can cause an unsafe drop in blood pressure.
     
Critical

Drug-Drug Interactions

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Critical
How does the drug interact with Repace A Tablet:
Using Losartan and Amlodipine together with dantrolene may increase the risk of hyperkalemia (high blood potassium).

How to manage the interaction:
Taking Losartan and Amlodipine with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
How does the drug interact with Repace A Tablet:
Coadministration of Ceritinib together with Losartan and Amlodipine can slow heart rate and increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is an interaction between Losartan and Amlodipine with Ceritinib, it can be taken if a doctor has advised it. However, consult the doctor if you have sudden dizziness, lightheadedness, fainting, or an irregular heartbeat. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Repace A Tablet:
Coadministration of Losartan and Amlodipine with Spironolactone can increase potassium levels in the blood, which can lead to severe conditions like kidney problems and irregular heart rhythm.

How to manage the interaction:
Taking Losartan and Amlodipine with Spironolactone is not recommended as it can result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, or tingling in your hands and feet. It is important to maintain proper fluid intake while taking these medications. Do not stop taking any medication without a doctor's advice.
How does the drug interact with Repace A Tablet:
Using enalapril together with Losartan and Amlodipine may increase the risk of side effects such as low blood pressure, kidney function impairment, and a condition called hyperkalemia (high blood potassium). In severe cases, hyperkalemia can lead to kidney problems, muscle paralysis, and irregular heart rhythm.

How to manage the interaction:
Although taking Enalapril with Losartan and Amlodipine may result in an interaction, they can be taken together if your doctor prescribes it. However, contact a doctor immediately if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. Do not discontinue any medication without consulting a doctor.
Severe
How does the drug interact with Repace A Tablet:
Coadministration of Losartan and Amlodipine with Captopril can increase potassium levels, which can lead to severe conditions like kidney failure, muscle paralysis, and irregular heart rhythm.

How to manage the interaction:
Taking Losartan and Amlodipine with Captopril together can result in an interaction, but it can be taken if your doctor has advised it. However, you should contact a doctor immediately if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Repace A Tablet:
Coadministration of Amlodipine and Rifapentine may significantly reduce the blood levels of amlodipine, which may make the medication less effective.

How to manage the interaction:
There may be a possibility of interaction between Repace A Tablet and Rifapentine, but it can be taken if prescribed by a doctor. If you have any symptoms, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Repace A Tablet:
Coadministration of Losartan and Amlodipine with Nitisinone may increase the blood levels and effects of Nitisinone.

How to manage the interaction:
Taking Nitisinone with Losartan and Amlodipine together can result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms or if you feel unwell after taking your medication, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Repace A Tablet:
Coadministration of Losartan and Amlodipine with Trimethoprim can increase potassium levels, which can lead to severe conditions like kidney problems.

How to manage the interaction:
Taking Losartan and Amlodipine with Trimethoprim together can result in an interaction, but it can be taken if your doctor has advised it. However, you should contact a doctor immediately if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat. Do not stop using any medications without talking to a doctor.
How does the drug interact with Repace A Tablet:
Coadministration of Losartan and Amlodipine with Perindopril can increase kidney problems and irregular heart rhythm.

How to manage the interaction:
Taking Losartan and Amlodipine with Perindopril together can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Losartan + AmlodipinePotassium citrate
Severe
How does the drug interact with Repace A Tablet:
Coadministration of Losartan and Amlodipine with Potassium citrate can increase potassium levels, which can lead to severe conditions like kidney failure, muscle paralysis, and irregular heart rhythm.

How to manage the interaction:
Taking Losartan and Amlodipine with Potassium citrate together can result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, or feelings of heaviness in your legs. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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AMLODIPINE-5MG+LOSARTAN-25MGPotassium rich foods
Moderate

Drug-Food Interactions

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AMLODIPINE-5MG+LOSARTAN-25MGPotassium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt

How to manage the interaction:
Taking Repace A Tablet with potassium-containing salt substitutes or potassium supplements can cause high levels of potassium in the blood. Avoid taking potassium-containing salt substitutes or potassium supplements while being treated with Repace A Tablet.

All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTI- HYPERTENSIVES]

FAQs

Repace A Tablet is used to treat high blood pressure (hypertension).

Repace A Tablet consists of Losartan and Amlodipine. Losartan lowers blood pressure and increases blood flow by preventing the narrowing of blood vessels. Amlodipine dilates (widens) blood vessels and increases blood flow. Altogether, Repace A Tablet helps to lower high blood pressure, chest pain (angina) and other conditions caused by coronary artery disease.

Repace A Tablet can cause high levels of potassium in the blood, leading to hyperkalaemia. Hence, it is not recommended to use potassium supplements along with Repace A Tablet . However, consult your doctor if you are already taking other medicines before starting Repace A Tablet .

Do not stop using Repace A Tablet even if you feel better. It should be strictly used as advised by your doctor to avoid the recurrence of symptoms and worsening of the disease.

The duration you take Repace A Tablet depends on your health needs and blood pressure control. Typically, high blood pressure requires ongoing treatment. Your doctor will closely monitor your progress and decide how long you should continue taking the medication. It's essential not to stop taking Repace A Tablet without consulting your doctor first, as they will adjust your treatment plan accordingly.

Follow a balanced diet in moderation, accentuating natural and healthy foods, fresh fruits and vegetables, whole grains, low-fat or fat-free dairy products, and lean protein sources like poultry, fish, legumes, nuts and seeds. Legumes like beans and lentils are also great additions. Remember to limit your sodium intake to help manage your blood pressure. Aim for variety and inclusivity in your diet to ensure you're getting all the essential nutrients. By following this diet, you'll be well on your way to supporting your overall health and well-being! If you have specific dietary needs or restrictions, always consult with a healthcare professional or registered dietitian for personalized guidance.

Yes, you can take Repace A Tablet on an empty stomach. However, if you experience stomach upset or discomfort, taking it with food may help alleviate these symptoms. Consult your doctor or pharmacist for personalized advice.

When managing hypertension with medication, it's crucial to monitor your blood pressure regularly and maintain open communication with your healthcare provider. This includes sharing any pre-existing kidney issues or concerns about pregnancy or breastfeeding. Additionally, be mindful of dehydration and potential allergic reactions, which can impact your overall well-being. By taking these precautions and being proactive about your health, you can effectively manage your hypertension and reduce the risk of related complications.

Ankle or leg swelling (oedema) is a recognised side effect of one of the active components in Repace A Tablet . It occurs because the medication relaxes blood vessels, which can sometimes cause fluid to pool in your lower extremities. This side effect is usually harmless, but you should talk to your doctor if the swelling is painful or worsens.

Adopting a healthy lifestyle is crucial when managing hypertension. Focus on consuming a balanced diet rich in whole foods, fruits, and vegetables and limiting your sodium intake. Regular exercise can also help maintain good heart health. Additionally, avoid smoking and alcohol consumption and find ways to manage stress, such as relaxation techniques or engaging in enjoyable activities. By making these lifestyle changes, you can significantly improve your overall health and well-being.

The most common side effects of the Repace A Tablet are ankle swelling, dizziness, flushing, headache, hyperkalaemia, palpitations, sleepiness, taste changes, tiredness, and upset stomach, which can have a lasting impact and vanish as time goes on. Inform your doctor if you feel more uncomfortable with the symptoms.

Repace A Tablet is not recommended for children under 6 years old. For children over 6, follow a doctor's instructions for proper dosing and usage. If your child has hypertension, consult with your doctor to discuss the best course of treatment, including medication and lifestyle changes. Your doctor will help you develop a plan to manage your child's condition and promote healthy habits.

Keep Repace A Tablet in its original container, stored at room temperature away from moisture and light. Keep it out of the reach of children and pets. When disposing of medication, don't flush it down the toilet. Instead, take unused or expired medicines to a pharmacy or drug take-back location. Ask your pharmacist or healthcare provider for guidance if you're unsure about proper disposal. Following these simple steps will help ensure safety and responsibility when storing and disposing of medication.

No, you should not stop taking Repace A Tablet even if your blood pressure readings are normal. High blood pressure is a chronic condition that is managed, not cured, by this medication. Stopping it suddenly can cause your blood pressure to spike dangerously. Talk to your doctor before making any changes to your treatment.

It is best to avoid or strictly limit alcohol while taking Repace A Tablet . Alcohol can widen your blood vessels further, which can cause a rapid drop in blood pressure when combined with this medicine, leading to dizziness, lightheadedness, or fainting. Talk to your doctor about what is safe for you.

While a persistent dry cough is less common with Repace A Tablet than with other types of blood pressure medications, it can still occur in some individuals. If you develop an ongoing dry cough that does not go away, talk to your doctor to determine the cause.

Yes, Repace A Tablet can affect how your kidneys work, especially if you already have kidney disease, heart failure, or severe dehydration. Your doctor will likely perform routine blood tests to check your kidney function and potassium levels while you are on this medication. Talk to your doctor if you notice any changes in how often you urinate.

Dizziness can occur, especially when you first start taking Repace A Tablet or when your dose is increased. If you feel dizzy, sit or lie down immediately until the feeling passes, and rise slowly when standing up. If the dizziness persists, is severe, or causes you to faint, talk to your doctor right away.

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Country of origin

India

Manufacturer/Marketer address

Sun Pharmaceutical Industries Ltd., SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - REP0005
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