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Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Repace AF Tablet

Repace AF Tablet is used to treat high blood pressure (hypertension). Hypertension is a medical condition in which blood pressure is elevated persistently in the arteries.

Repace AF Tablet contains Losartan and Amlodipine. Losartan lowers blood pressure and increases blood flow by preventing the narrowing of blood vessels. Amlodipine dilates (widens) blood vessels and increases blood flow.

In some cases, Repace AF Tablet can cause side effects like sleepiness, taste changes, headache, dizziness, tiredness, and upset stomach. Most of these side effects do not require medical attention and resolve over time. However, if these side effects persist longer, please consult your doctor.

If you are known to be allergic to Repace AF Tablet or any other medicines, please inform your doctor. Before taking Repace AF Tablet , let your doctor know if you have any kidney or liver problems or severe dehydration.

Uses of Repace AF Tablet

Repace AF Tablet is used in the treatment of High blood pressure (hypertension). The detailed uses of Repace AF Tablet are as follows:

  • Blood Pressure Management: Through blood vessel relaxation and a reduction in blood vessel resistance, Repace AF Tablet is used to treat hypertension.
  • Cardiovascular Risk Reduction: Repace AF Tablet helps to reduce the risk of cardiovascular events such as heart attacks and strokes.
  • Cardiovascular Health: Repace AF Tablet improves blood circulation and heart function.

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Directions for Use

  • Repace AF Tablet can be taken with or without food as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Repace AF Tablet as a whole with a glass of water.
  • Do not crush, break, or chew it.

Medicinal Benefits

  • Repace AF Tablet is a combination anti-hypertensive medicine used to treat high blood pressure (hypertension) and related heart conditions.
  • It contains Losartan and Amlodipine, which work together to improve blood flow and reduce strain on the heart.
  • It helps reduce elevated blood pressure, decreasing the risk of stroke, heart attack, and kidney problems.
  • Losartan (an angiotensin II receptor antagonist) prevents blood vessel narrowing, promoting smooth blood flow.
  • Amlodipine (a calcium channel blocker) relaxes blood vessel walls, improving circulation and lowering pressure.
  • It reduces the heart’s workload, helping it pump blood more efficiently.
  • It improves oxygen supply to the heart muscles, helping prevent or reduce chest discomfort caused by coronary artery disease.
  • The dual mechanism of action provides better blood pressure control and improved cardiovascular outcomes compared to single-drug therapy.

How Repace AF Tablet Works

Repace AF Tablet is a combination of two medicines, namely, Losartan and Amlodipine. Losartan belongs to a group of drugs called angiotensin II receptor antagonists. It lowers the blood pressure and increases the blood flow by preventing the narrowing of blood vessels. Amlodipine is a calcium channel blocker that dilates (widens) blood vessels and increases blood flow. Altogether, it helps to lower high blood pressure.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Repace AF Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the steps to manage angioedema (Swelling Under The Skin) as a side effect of medication:
  • If you experience angioedema, inform your doctor immediately. Treatment can help keep the swelling under control.
  • Seek medical attention if symptoms are severe, such as difficulty breathing or swallowing.
  • Follow your doctor's instructions to manage symptoms, which may include stopping or adjusting the medication that triggered angioedema.
  • Your doctor may also recommend antihistamines, steroids, or other treatments to reduce swelling and inflammation.
  • Make dietary and lifestyle changes as recommended, such as avoiding trigger foods or reducing stress.
  • Monitor your condition closely and track your symptoms to report them to your doctor.
  • Consult your doctor again if symptoms worsen or do not improve or if you experience any new or concerning symptoms.
  • Limit fruit intake to two servings a day, choose a low-potassium options like apples and strawberries.
  • Restrict starchy vegetables like potatoes and pumpkin to half a cup daily.
  • Avoid or limit foods like tomato products, high-bran cereals, and salty or sugary snacks.
  • Limit dairy products to 200g of yoghurt or 300ml of milk per day.
  • If you experience low blood sugar levels, inform your doctor. They will assess the severity and make recommendations for the next actions.
  • Your doctor will assess your symptoms, blood sugar levels, and overall health before recommending the best course of action, which may include treatment, lifestyle modifications, or prescription adjustments.
  • Follow your doctor's instructions carefully to manage the episode and adjust your treatment plan.
  • Make medication adjustments as recommended by your doctor to prevent future episodes.
  • Implement diet and lifestyle modifications as your doctor advises to manage low blood sugar levels.
  • Monitor your blood sugar levels closely for patterns and changes.
  • Track your progress by recording your blood sugar levels, food intake, and physical activity.
  • Seek further guidance from your doctor if symptoms persist or worsen so that your treatment plan can be revised.

What if I have taken an overdose of Repace AF Tablet

An overdose of Repace AF Tablet may cause unpleasant side effects. If you suspect you have taken an overdose, please consult a doctor immediately.

Drug Warnings

  • If you are known to be allergic to Repace AF Tablet or have any kidney or liver problems or severe dehydration, please inform your doctor beforehand.
  • Pregnant or breastfeeding women should also consult their doctor before taking this medicine.
  • Complete the course as suggested by the doctor, even if you feel better, to avoid disease recurrence.
  • Avoid consumption of alcohol with Repace AF Tablet as it may increase the risk of low blood pressure.
  • Avoid potassium supplements with Repace AF Tablet as it may lead to high potassium levels in the blood.
  • Let your doctor know if you are taking any other medicines, including supplements or herbal products.

Drug-Drug Interactions

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AmlodipineDantrolene
Critical

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
How does the drug interact with Repace AF Tablet:
Using Repace AF Tablet together with dantrolene may increase the risk of hyperkalemia (high blood potassium).

How to manage the interaction:
Taking Repace AF Tablet with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
How does the drug interact with Repace AF Tablet:
Coadministration of Repace AF Tablet with itraconazole may significantly raise the blood levels and effects of Repace AF Tablet.

How to manage the interaction:
Repace AF Tablet and itraconazole may interact, but if prescribed by a doctor, they can be used together. Consult a doctor if you develop chest discomfort, trouble breathing, dizziness or fainting, swelling of the hands, ankles, or feet, or any other of these symptoms. Without consulting a doctor, never stop taking any medication.
AmlodipineRifapentine
Severe
How does the drug interact with Repace AF Tablet:
Coadministration of Repace AF Tablet and Rifapentine may significantly reduce the blood levels of Repace AF Tablet, which may make the medication less effective.

How to manage the interaction:
There may be a possibility of interaction between Repace AF Tablet and Rifapentine, but it can be taken if prescribed by a doctor. If you have any symptoms, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
AmlodipineIdelalisib
Severe
How does the drug interact with Repace AF Tablet:
Coadministration of Repace AF Tablet and Idelalisib may raise Repace AF Tablet levels in the blood this may lead to serious side effects (irregular heart rhythm, fluid retention, swelling, heart failure, and abnormally low blood pressure).

How to manage the interaction:
Although taking Repace AF Tablet with idelalisib can result in an interaction, it can be taken if a doctor has advised it. However, if you experience dizziness or fainting, sudden, unexplained weight gain, swelling of the hands, ankles, or feet, chest discomfort, or trouble breathing while taking these drugs, consult the doctor. Use caution while getting up from a sitting or sleeping position and avoid driving or using dangerous machinery. Do not stop using any medications without a doctor's advice.
How does the drug interact with Repace AF Tablet:
Coadministration of Repace AF Tablet and carbamazepine together may significantly reduce Repace AF Tablet blood levels, making the medicine less effective.

How to manage the interaction:
Although there is an interaction between Repace AF Tablet with carbamazepine, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms contact the doctor immediately. Do not stop using any medications without talking to a doctor.
AmlodipineMitotane
Severe
How does the drug interact with Repace AF Tablet:
Using Repace AF Tablet and mitotane together may drastically lower Repace AF Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of Repace AF Tablet with mitotane can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineFosphenytoin
Severe
How does the drug interact with Repace AF Tablet:
When Repace AF Tablet is taken with Fosphenytoin, it may decrease the blood levels of Repace AF Tablet, which may make Repace AF Tablet less effective.

How to manage the interaction:
Although taking Repace AF Tablet and Fosphenytoin together can cause an interaction, it can be taken if a doctor has suggested it. Do not stop using any medications without a doctor's advice.
AmlodipineDolasetron
Severe
How does the drug interact with Repace AF Tablet:
Using dolasetron together with Repace AF Tablet can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
There may be a possibility of interaction between Repace AF Tablet and Dolasetron, but it can be taken if prescribed by a doctor. If you have any of these symptoms, like feeling dizzy, lightheaded, or your heart beating irregularly, it's important to call a doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Repace AF Tablet:
Using phenobarbital and Repace AF Tablet may drastically lower Repace AF Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of phenobarbital with Repace AF Tablet can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Repace AF Tablet:
Using Repace AF Tablet and rifabutin together may lower Repace AF Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although there is an interaction between Repace AF Tablet with rifabutin, but it can be taken if a doctor has advised it. Consult the doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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AMLODIPINE-5MG+LOSARTAN-50MGPotassium rich foods
Moderate

Drug-Food Interactions

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AMLODIPINE-5MG+LOSARTAN-50MGPotassium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt

How to manage the interaction:
Taking Repace AF Tablet with potassium-containing salt substitutes or potassium supplements can cause high levels of potassium in the blood. Avoid taking potassium-containing salt substitutes or potassium supplements while being treated with Repace AF Tablet.

Diet & Lifestyle Advise

  • Reduce sodium intake in your diet to maintain your blood pressure.
  • Eat natural and healthy foods by cutting down on high-sodium processed foods.
  • Lose those extra pounds, since being obese can be a risk factor for hypertension.
  • Exercise regularly to maintain good heart health.
  • Avoid smoking and alcohol intake.
  • Chronic stress may also cause high blood pressure. Therefore, avoid stress triggers and make time for yourself to relax and do activities that you enjoy.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES
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Alcohol

Unsafe

It is unsafe to consume alcohol, since alcohol consumption with Repace AF Tablet may increase the risk of low blood pressure and cause adverse effects such as dizziness, fainting, light-headedness, or headache.

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Pregnancy

Caution

Please consult your doctor before taking Repace AF Tablet if you plan to become pregnant or are already pregnant. Your doctor will weigh the potential risks and benefits before prescribing Repace AF Tablet .

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Breast Feeding

Caution

There is no evidence on how Repace AF Tablet affects breastfeeding. Please consult your doctor before taking Repace AF Tablet if you are breastfeeding.

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Driving

Caution

Repace AF Tablet may cause side effects like dizziness, headaches, nausea or tiredness, which can affect your ability to concentrate and drive. Hence, it is recommended not to drive or operate machinery until you are mentally alert.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before taking Repace AF Tablet . The dosage will be initiated in lower doses and will be further increased in patients with liver diseases.

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Kidney

Caution

Repace AF Tablet consists of Losartan, which may affect kidney function. Hence, it is advised to seek a doctor's advice before starting Repace AF Tablet if you have kidney problems.

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Children

Caution

It is not recommended for children below six years. However, for children above six years, give Repace AF Tablet in doses as prescribed by a doctor.

FAQs

Repace AF Tablet is used to treat high blood pressure (hypertension).

Repace AF Tablet consists of Losartan and Amlodipine. Losartan lowers blood pressure and increases blood flow by preventing the narrowing of blood vessels. Amlodipine dilates (widens) blood vessels and increases blood flow. Altogether, Repace AF Tablet helps to lower high blood pressure, chest pain (angina) and other conditions caused by coronary artery disease.

Repace AF Tablet can cause high levels of potassium in the blood, leading to hyperkalaemia. Hence, it is not recommended to use potassium supplements along with Repace AF Tablet . However, consult your doctor if you are already taking other medicines before starting Repace AF Tablet .

Do not stop using Repace AF Tablet even if you feel better. It should be strictly used as advised by your doctor to avoid the recurrence of symptoms and worsening of the disease.

The duration you take Repace AF Tablet depends on your health needs and blood pressure control. Typically, high blood pressure requires ongoing treatment. Your doctor will closely monitor your progress and decide how long you should continue taking the medication. It's essential not to stop taking Repace AF Tablet without consulting your doctor first, as they will adjust your treatment plan accordingly.

Follow a balanced diet in moderation, accentuating natural and healthy foods, fresh fruits and vegetables, whole grains, low-fat or fat-free dairy products, and lean protein sources like poultry, fish, legumes, nuts and seeds. Legumes like beans and lentils are also great additions. Remember to limit your sodium intake to help manage your blood pressure. Aim for variety and inclusivity in your diet to ensure you're getting all the essential nutrients. By following this diet, you'll be well on your way to supporting your overall health and well-being! If you have specific dietary needs or restrictions, always consult with a healthcare professional or registered dietitian for personalized guidance.

Yes, you can take Repace AF Tablet on an empty stomach. However, if you experience stomach upset or discomfort, taking it with food may help alleviate these symptoms. Consult your doctor or pharmacist for personalized advice.

When managing hypertension with medication, it's crucial to monitor your blood pressure regularly and maintain open communication with your healthcare provider. This includes sharing any pre-existing kidney issues or concerns about pregnancy or breastfeeding. Additionally, be mindful of dehydration and potential allergic reactions, which can impact your overall well-being. By taking these precautions and being proactive about your health, you can effectively manage your hypertension and reduce the risk of related complications.

Yes, you may feel dizzy after taking Repace AF Tablet . This is one of the most common side effects of Repace AF Tablet because it lowers blood pressure and increases blood flow, which makes you feel dizzy, especially during quick actions (standing, walking, lying). To manage it, stay hydrated and take slow actions while sitting or lying. If dizziness is increasing, consult your doctor; he will help you manage your condition.

Please consult your doctor before taking Repace AF Tablet if you plan to become pregnant or are already pregnant. Your doctor will weigh the potential risks and benefits before prescribing Repace AF Tablet .

Adopting a healthy lifestyle is crucial when managing hypertension. Focus on consuming a balanced diet rich in whole foods, fruits, and vegetables and limiting your sodium intake. Regular exercise can also help maintain good heart health. Additionally, avoid smoking and alcohol consumption and find ways to manage stress, such as relaxation techniques or engaging in enjoyable activities. By making these lifestyle changes, you can significantly improve your overall health and well-being.

The most common side effects of the Repace AF Tablet are ankle swelling, dizziness, flushing, headache, hyperkalaemia, palpitations, sleepiness, taste changes, tiredness, and upset stomach, which can have a lasting impact and vanish as time goes on. Inform your doctor if you feel more uncomfortable with the symptoms.

Repace AF Tablet is not recommended for children under 6 years old. For children over 6, follow a doctor's instructions for proper dosing and usage. If your child has hypertension, consult with your doctor to discuss the best course of treatment, including medication and lifestyle changes. Your doctor will help you develop a plan to manage your child's condition and promote healthy habits.

Keep Repace AF Tablet in its original container, stored at room temperature away from moisture and light. Keep it out of the reach of children and pets. When disposing of medication, don't flush it down the toilet. Instead, take unused or expired medicines to a pharmacy or drug take-back location. Ask your pharmacist or healthcare provider for guidance if you're unsure about proper disposal. Following these simple steps will help ensure safety and responsibility when storing and disposing of medication.

Country of origin

India

Manufacturer/Marketer address

Sun Pharmaceutical Industries Ltd., SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - REP0004

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