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compositionComposition:TENOFOVIR DISOPROXIL-300MG
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Reviro 300mg Tablet is used to treat HIV infection and chronic hepatitis B. It contains Tenofovir disoproxil, which works by interfering with the normal working of enzymes (reverse transcriptase in HIV and DNA polymerase in HBV) that are essential for the production of viruses. It may cause common side effects such as diarrhoea, vomiting, nausea, bloating, flatulence, weakness, dizziness, headache, abdominal pain, and fatigue. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

TENOFOVIR DISOPROXIL-300MG

Manufacturer/Marketer :

Dr Reddy's Laboratories Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Reviro 300mg Tablet

Reviro 300mg Tablet is a prescription oral medication used to manage human immunodeficiency virus type 1 (HIV-1) and chronic hepatitis B virus infections. It works by stopping the virus from multiplying in your body, which helps keep your immune system strong and reduces the risk of active liver damage. This medicine does not cure HIV-1 or hepatitis B, but it helps manage these long-term conditions effectively.

To get the best results, you must take Reviro 300mg Tablet consistently every single day at the same time, exactly as your doctor tells you. You can take this tablet with or without food, though taking it with a meal may help if you experience a mild upset stomach. Maintaining a balanced diet and staying well-hydrated are helpful lifestyle habits that support your body while on this treatment.

While taking Reviro 300mg Tablet , you might experience common, mild side effects such as nausea, diarrhea, or feeling unusually tired. However, you must seek medical attention immediately if you notice signs of serious conditions, such as severe stomach pain, unusual muscle pain, or signs of kidney trouble. Your doctor will monitor your health closely to ensure the medication is working safely.

Before starting this treatment, tell your healthcare provider if you have a history of kidney disease, liver problems, or bone thinning. Do not take this medicine if you are already taking other medications that contain the same active ingredients or are known to harm your kidneys. It is also vital to share if you have both HIV-1 and hepatitis B, as stopping this medicine can cause your hepatitis B to worsen suddenly.

Reviro 300mg Tablet can interact with certain pain relievers or other antiviral drugs, which may increase the risk of kidney damage. Avoid drinking alcohol while taking this medicine, as it can place extra stress on your liver. If you are pregnant, planning to become pregnant, breastfeeding, or are an older adult, consult your doctor or pharmacist to discuss the risks and benefits.

Uses of Reviro 300mg Tablet

Reviro 300mg Tablet is used in the treatment of HIV (Human Immunodeficiency Virus) infection and Chronic Hepatitis. The detailed uses of Reviro 300mg Tablet are as follows:

  • HIV-1 Infection: Reviro 300mg Tablet is used in combination with other antiviral medicines to control the virus, protect the immune system, and lower the risk of developing infections.
  • Chronic Hepatitis B: This medicine helps lower the amount of hepatitis B virus in your body, reducing active liver inflammation and preventing long-term liver damage.
  • HIV-1 Pre-Exposure Prophylaxis (PrEP): It is used in combination with other specific antiviral medications to help prevent HIV infection in individuals who are at a higher risk

Key Benefits

  • Immune System Protection (For HIV Management): By keeping the viral load (amount of virus) in your blood extremely low, this medication helps protect your immune cells from being damaged. This keeps your immune system stronger and much better equipped to fight off everyday infections, helping you stay active and healthy.
  • Long-Term Liver Support (For Chronic Hepatitis B): The medication works continuously to slow down and reduce viral activity directly inside the liver. This significantly reduces active inflammation, helps prevent severe liver scarring (cirrhosis), and lowers the risk of long-term liver complications, providing vital support for your ongoing health.
Side effects of Reviro 300mg Tablet
  • Apply a hot/cold pack to the affected area.
  • Doing gentle exercises can help cope with pain by stretching muscles.
  • Get enough sleep. It helps enhance mood and lower pain sensitivity.
  • Avoid alcohol, smoking and tobacco as they can increase pain.
  • Follow a well-balanced meal.
  • Meditation and massages may also help with pain.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.

Directions for Use

  • Swallow the tablet whole with a full glass of water. Do not crush, chew, or split the tablet, as this can affect how the medicine is absorbed into your body.
  • Always follow your doctor's exact instructions regarding how to take this medicine, and never stop taking it without consulting them first.
  • Take your dose at the same time every day to keep a steady level of the medicine in your bloodstream.
  • You can take it with or without food, but keeping a consistent routine is key to managing your condition effectively.
     

How Reviro 300mg Tablet Works

This medicine contains Tenofovir disoproxil. Reviro 300mg Tablet belongs to a class of antiviral medications that act as blockers inside infected cells. When a virus like HIV-1 or hepatitis B attempts to replicate, it relies on specific proteins and enzymes to build new copies of its genetic material. Once you take Reviro 300mg Tablet , the active medicine is absorbed and converted inside your cells. It then mimics the natural building blocks of the virus's DNA. When the virus tries to use this mimic to build its DNA chain, the process is abruptly cut short. This prevents the virus from multiplying, successfully lowering the viral load in your body and allowing your immune system to recover.
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Alcohol

Caution

Consuming alcohol while using Reviro 300mg Tablet may worsen the condition.

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Pregnancy

Caution

Reviro 300mg Tablet is a category B medicine. It should be used with caution in pregnant women.

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Breast Feeding

Caution

In the case of chronic hepatitis B, Reviro 300mg Tablet should be used in breastfeeding mothers only if clinically needed. Avoid breastfeeding if you have HIV.

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Driving

Caution

Reviro 300mg Tablet may cause dizziness. So, avoid driving if you feel dizzy.

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Liver

Caution

Reviro 300mg Tablet should be used with caution if you have liver disease. Dose adjustments may be necessary.

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Kidney

Caution

Reviro 300mg Tablet should not be used in adolescents with kidney failure. In other people with severe kidney diseases, Reviro 300mg Tablet is prescribed only if clinically needed.

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Children

Caution

Reviro 300mg Tablet should be used with caution in children below 12 years of age.

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Heart

Consult your doctor

Inform your doctor if you have any existing heart disease. Your doctor will prescribe this medicine only if the potential benefits outweigh the risks.

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Geriatrics

Caution

Limited information is available regarding the usage of Reviro 300mg Tablet in elders, so please consult a doctor if you have any concerns.

What if I have taken an overdose of Reviro 300mg Tablet

If you take too much of this medicine, seek immediate emergency medical attention or contact a poison control centre right away.

Diet & Lifestyle Advise

  • Drink plenty of water: Because this medication is processed by your kidneys, staying well-hydrated helps your kidneys flush out waste products effectively.
  • Limit alcohol intake: Alcohol can strain your liver and increase the risk of liver damage, especially if you are treating chronic hepatitis B.
  • Eat bone-supporting foods: Since this medication can sometimes cause bone thinning, make sure your diet includes adequate calcium and Vitamin D, or discuss supplements with your doctor.
  • Avoid self-medicating with pain relievers: Common over-the-counter pain medicines like ibuprofen can strain your kidneys. Always ask your pharmacist for kidney-safe alternatives.

Health Queries

Is it safe and appropriate to take Reviro 300 (once daily) and Udimarin (twice daily) for Hepatitis B recovery if I also have diabetes?

Veda Maddala

Veda Maddala

M Pharmacy

Yes, it is generally safe to take tenofovir (once daily) and ursodeoxycholic acid (twice daily) for Hepatitis B recovery if you have diabetes. There are no direct harmful interactions between these medications. However, because both diabetes and tenofovir can impact your kidney function over time, it is very important to have your kidney health monitored regularly by your doctor. Additionally, keeping your blood sugar well-controlled is essential, as improving your liver health can also positively influence your diabetes management. Always consult your physician to ensure your treatment plan is perfectly tailored to your health needs.

I am a Hepatitis B patient and have been taking Tenvir for the past two years. Although my HBV DNA level is now zero, my doctor advised me to continue the medication. Recently, I have been experiencing severe hair loss and back pain from my hips to my neck, making me feel as though my bones are weak. Are these symptoms side effects of Tenvir or Hepatitis B, and what medical advice or alternative treatments should I discuss with my doctor?

Dr. S Aneela

Dr. S Aneela

M. Pharm (Pharmacology)., PhD

It is excellent that your viral load is undetectable. However, stopping treatment can cause the virus to reactivate, which is why your doctor advised continuing. Your back pain and feeling of weak bones may be side effects of Tenvir (tenofovir disoproxil fumarate), which can sometimes reduce bone density. Hair loss is less common but possible. Please do not stop your medication. Instead, consult your doctor to discuss these symptoms. They may recommend a bone density scan (DEXA) and check your kidney function. You can also discuss switching to alternative medications with a better bone safety profile, such as tenofovir alafenamide or entecavir.
health query

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How Soon It Starts Working

The time required for Reviro 300mg Tablet to start to work: The time required for Reviro 300mg Tablet to start to work is 1 to 2 hours after administration. The time for which the effects of Reviro 300mg Tablet last: The duration of action for Reviro 300mg Tablet is not clinically established.

What if you forget to take Reviro 300mg Tablet

If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not take two doses at the same time to make up for a missed one.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Do not stop taking Reviro 300mg Tablet suddenly: Stopping this treatment abruptly if you have hepatitis B can cause a severe, life-threatening flare-up of the infection.
  • Check your tablets before taking: Always inspect the tablets before taking your dose; do not use them if they are discolored, cracked, or show signs of moisture damage.
  • Disclose all your medications: Tell every doctor you see that you are taking Reviro 300mg Tablet , especially before starting any new prescription or over-the-counter drugs.
  • Practice safe habits: This medicine reduces the amount of virus in your body but does not prevent the transmission of HIV-1 or hepatitis B to others through sexual contact or blood sharing.

Drug-Drug Interactions

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Drug-Drug Interactions:

  • Kidney-damaging medicines: Taking this medicine with other drugs that can affect kidney function (such as certain antibiotics or high-dose pain relievers like ibuprofen) can increase the risk of serious kidney damage.
  • Other antivirals: Combining Reviro 300mg Tablet with other hepatitis or HIV antivirals may alter medication levels in your body, increasing the risk of side effects.

Drug-Food Interactions:

  • High-fat meals: In some cases, taking certain formulations of this medicine with a very high-fat meal can significantly increase how much drug is absorbed, potentially increasing side effects. Check with your pharmacist regarding your specific brand.

Drug-Disease Interactions:

  • Kidney disease: If you have pre-existing kidney problems, this medicine can accumulate in your body, increasing the risk of side effects. Your doctor may need to adjust your dosing schedule.
  • Hepatitis B and HIV co-infection: If you have both infections, taking this medicine without a complete HIV treatment plan can cause the HIV virus to become resistant to treatment.
Tenofovir disoproxilStreptozocin
Critical
Tenofovir disoproxilDidanosine
Critical

Drug-Drug Interactions

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Tenofovir disoproxilStreptozocin
Critical
How does the drug interact with Reviro 300mg Tablet:
Combining Reviro 300mg Tablet and Streptozocin can increase the risk of kidney problems.

How to manage the interaction:
Taking Reviro 300mg Tablet with Streptozocin is not recommended, as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without talking to your doctor.
Tenofovir disoproxilDidanosine
Critical
How does the drug interact with Reviro 300mg Tablet:
Coadministration of Didanosine with Reviro 300mg Tablet can increase the levels and risk of Didanosine side effects.

How to manage the interaction:
Taking Didanosine with Reviro 300mg Tablet is not recommended, please consult your doctor before taking it. It can be taken if your doctor prescribes it. However, if you experience severe headaches, confusion, weakness, trouble walking, muscle pain, or high fever, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Tenofovir disoproxilCisplatin
Severe
How does the drug interact with Reviro 300mg Tablet:
Coadministration of Cisplatin and Reviro 300mg Tablet can increase the risk of kidney damage and reduce kidney function.

How to manage the interaction:
Taking Cisplatin and Reviro 300mg Tablet together can lead to an interaction, it can be taken when advised by your doctor. However, if you experience any symptoms like nausea, vomiting, irregular urination, sudden weight gain or weight loss, shortness of breath, muscle cramps, dizziness, and irregular heart rhythm, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
Tenofovir disoproxilTobramycin
Severe
How does the drug interact with Reviro 300mg Tablet:
Coadministration of tobramycin with Reviro 300mg Tablet can increase the risk of kidney problems.

How to manage the interaction:
Taking Reviro 300mg Tablet with Tobramycin together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
Tenofovir disoproxilPiroxicam
Severe
How does the drug interact with Reviro 300mg Tablet:
Coadministration of Piroxicam and Reviro 300mg Tablet can increase the risk of kidney damage.

How to manage the interaction:
Co-administration of Reviro 300mg Tablet with Piroxicam can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, decreased appetite, increased or decreased urine, weight gain or loss that occurs suddenly, swelling, difficulty breathing, muscle pain, dizziness, and irregular heartbeat, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
Tenofovir disoproxilAmikacin
Severe
How does the drug interact with Reviro 300mg Tablet:
Coadministration of Reviro 300mg Tablet with Amikacin can increase the risk of developing kidney problems.

How to manage the interaction:
Although taking Amikacin and Reviro 300mg Tablet together can result in an interaction, it can be taken when a doctor has prescribed it. Consult the doctor if you experience vomiting, loss of appetite, irregular urination, sudden weight gain or loss, shortness of breath, weakness, or dizziness. Do not discontinue any medications without a doctor's advice.
Tenofovir disoproxilRifampicin
Severe
How does the drug interact with Reviro 300mg Tablet:
Rifampin may significantly lower the tenofovir levels in your blood, possibly decreasing its effectiveness in treating your condition.

How to manage the interaction:
Although taking Rifampicin together with Reviro 300mg Tablet can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Tenofovir disoproxilPolymyxin b
Severe
How does the drug interact with Reviro 300mg Tablet:
Coadministration of Reviro 300mg Tablet with Polymyxin B can increase the risk of side effects.

How to manage the interaction:
Taking Reviro 300mg Tablet with Polymyxin B together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor immediately. Do not stop using any medications without consulting a doctor.
Tenofovir disoproxilNeomycin
Severe
How does the drug interact with Reviro 300mg Tablet:
Coadministration of Neomycin and Reviro 300mg Tablet can increase the risk of developing kidney problems.

How to manage the interaction:
Taking Neomycin and Reviro 300mg Tablet together can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, shortness of breath, muscle cramps, dizziness, and irregular heart rhythm, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
Tenofovir disoproxilPrimidone
Severe
How does the drug interact with Reviro 300mg Tablet:
Coadministration of Primidone and Reviro 300mg Tablet can increase the risk of developing Reviro 300mg Tablet side effects.

How to manage the interaction:
Taking Reviro 300mg Tablet and Primidone together can possibly result in an interaction, it can be taken if prescribed by a doctor. However, if you experience any symptoms like dizziness, diarrhea, headache, or trouble sleeping, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIRETROVIRAL AGENTS]

FAQs

Reviro 300mg Tablet is used to treat HIV infection and chronic hepatitis B.
Reviro 300mg Tablet does not affect fertility. However, consult your doctor immediately if you develop any side effects while using Reviro 300mg Tablet .
Reviro 300mg Tablet should be taken as prescribed by your doctor. Abrupt stopping of this medicine may lead to resistance to other medications making the infection difficult to treat.
Reviro 300mg Tablet is used to treat HIV-1 virus so you can take the Reviro 300mg Tablet but if you are suffering with tuberculosis then you should consult the doctor. Inform about your medical conditions and take Reviro 300mg Tablet only if it is advised by your physician. Do not self-medicate.
In case of HIV-1 infection, Reviro 300mg Tablet may reduce the risk of passing the virus to others, but the chances of infecting others can still be there. In case of HBV infection, Reviro 300mg Tablet has not proven to reduce the risk of passing the virus to others.
You should take the Reviro 300mg Tablet for as long as it is prescribed by the doctor. Do not stop using it without the notice of the doctor until the course is completed as it may worsen your condition.
If you vomit within 1 hour of taking Reviro 300mg Tablet , then take the other tablet. If you vomit more than 1 hour after taking Reviro 300mg Tablet , then do not take another dose.
No, Reviro 300mg Tablet does not cure HIV-1 or hepatitis B. Instead, it helps control the virus, lowers the viral load in your body, and protects your immune system and liver from further damage. Talk to your doctor about long-term management goals.
Some pregnant individuals may need to continue this medication to protect their health and prevent passing the virus to the baby. However, you must discuss the risks and benefits with your doctor to make a safe, individualized plan.
Reviro 300mg Tablet is processed by the kidneys and can sometimes cause kidney damage or decreased kidney function over time. Your doctor will order regular blood and urine tests to monitor your kidney health while you are on this medicine. Talk to your doctor if you experience changes in urination.
It is highly recommended to avoid or strictly limit alcohol while taking Reviro 300mg Tablet . Alcohol can place extra strain on your liver and increase the risk of liver damage, particularly if you are treating chronic hepatitis B. Talk to your doctor for personalized advice.
You should avoid taking frequent or high doses of pain relievers like ibuprofen while taking Reviro 300mg Tablet , as both can strain your kidneys and increase the risk of kidney problems. Speak to your pharmacist or doctor about safer alternatives for pain relief.
Yes, Reviro 300mg Tablet can sometimes cause a reduction in bone mineral density, which may increase the risk of bone thinning or fractures. Your doctor may monitor your bone health and recommend calcium or Vitamin D supplements. Talk to your doctor if you have a history of bone issues.

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Country of origin

India

Manufacturer/Marketer address

Dr. Reddy's Laboratories Ltd., 8-2-337, Road No. 3, Banjara Hills, Hyderabad, Telangana 500034, INDIA
Other Info - REV0227
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