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  3. Rifagrap-M Tablet 10's

Rifagrap-M Tablet 10's, Pack of 10
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Written By ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Rifagrap-M Tablet 10's is used to treat bacterial infections, particularly those affecting the gastrointestinal tract, such as intestinal and parasitic infections. It eliminates harmful bacteria and prevents their growth. Common side effects may include nausea, diarrhea, abdominal pain, headache, dizziness, or a metallic taste.

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Composition :

METRONIDAZOLE-400Mg + RIFAXIMIN-200Mg

Manufacturer/Marketer :

Grapple Life Sciences Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Rifagrap-M Tablet 10's

Rifagrap-M Tablet 10's is an antibiotic combination used to treat bacterial and gastrointestinal infections (including traveller's diarrhoea and irritable bowel syndrome). Gastrointestinal infections are conditions caused by harmful microorganisms, such as bacteria, viruses, or parasites, that affect the digestive system. They often lead to symptoms like nausea, vomiting, diarrhoea, and abdominal pain.

Rifagrap-M Tablet 10's is a combination of Metronidazole and Rifaximin. Metronidazole is an antimicrobial agent that kills bacteria and protozoa by disrupting their DNA. Rifaximin is a non-absorbable antibiotic that works directly in the gut to inhibit bacterial growth. Together, they help relieve symptoms, prevent complications, and promote intestinal health.

Give Rifagrap-M Tablet 10's to your child as prescribed by the doctor. It can cause side effects like nausea, diarrhea, abdominal pain, headache, dizziness, or a metallic taste. These effects are usually temporary and do not require medical attention. However, if they continue or worsen, see your doctor for advice.

If your child is allergic to other medicines, please tell the doctor. Rifagrap-M Tablet 10's should be used only in doses prescribed by a doctor for children. It is recommended that you complete the entire course of Rifagrap-M Tablet 10's as prescribed by the doctor, even if your child feels better after a few days. Rifagrap-M Tablet 10's is used with caution in children with heart, liver/kidney disorder, colitis, blood dyscrasias, or neurologic toxicity.

Uses of Rifagrap-M Tablet 10's

Rifagrap-M Tablet 10's is used in the treatment of Traveller’s Diarrhoea, Small Intestinal Bacterial Overgrowth, and Irritable Bowel Syndrome (IBS) in children. The detailed uses of Rifagrap-M Tablet 10's are as follows:

  • Traveller’s Diarrhoea (TD): Rifagrap-M Tablet 10's effectively manages symptoms of traveller’s diarrhoea by combating bacterial and protozoal infections that cause gastrointestinal distress.
  • Treatment of Small Intestinal Bacterial Overgrowth: Rifagrap-M Tablet 10's helps reduce excessive bacterial growth in the small intestine.
  • Irritable Bowel Syndrome: Rifagrap-M Tablet 10's may help alleviate symptoms of IBS, such as abdominal pain, bloating, and diarrhea, by targeting gut bacteria and reducing inflammation.

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Directions for Use

  • Rifagrap-M Tablet 10's can be taken with or without food.
  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Administer the advised dose to the child using the measuring cup/measuring spoon/dropper.
  • Shake the bottle well before use.

Medicinal Benefits

Rifagrap-M Tablet 10'scombines the benefits of two antibiotics to treat a variety of gastrointestinal conditions. Metronidazole targets bacterial infections and helps treat conditions like gut infections, abscesses, and certain parasitic infections. Rifaximin, a non-absorbable antibiotic, is effective against bacterial overgrowth in the intestines and helps manage conditions like irritable bowel syndrome (IBS) and hepatic encephalopathy. Together, they support gut health, reduce bacterial infections, and improve overall digestive function.

How Rifagrap-M Tablet 10's Works

Rifagrap-M Tablet 10's is a combination of Metronidazole and Rifaximin. Metronidazole is an antimicrobial agent that kills bacteria and protozoa by disrupting their DNA. Rifaximin is a non-absorbable antibiotic that works directly in the gut to inhibit bacterial growth. Together, they help relieve symptoms, prevent complications, and promote intestinal health.

Storage

• Store in a cool and dry place away from sunlight.• Keep Rifagrap-M Tablet 10's out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Rifagrap-M Tablet
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
  • Inflammation of Vagina needs immediate attention and cannot be ignored.
  • Get a physical examination and prevent wearing clothes that can hold heat and moisture.
  • Avoid using vaginal sprays or perfumed soaps that increase itching and irritation.
  • Follow your doctor's instructions, and rest well with proper medication.
  • Take a balanced diet and get regular screenings to reduce inflammation.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Eat fiber-rich foods like whole grains, fruits, vegetables, and legumes to promote regular bowel movements.
  • Drink plenty of water to soften stool and make it easier to pass.
  • Avoid trigger foods like dairy, gluten, or spicy foods that can worsen constipation.
  • Exercise regularly, like walking or yoga, to stimulate bowel movements.
  • Practice yoga and pelvic floor exercises to strengthen muscles involved in bowel movements.
  • Inform your doctor if you experience severe symptoms like abdominal pain, vomiting, or blood in the stool.
  • Defecation urgency can bother you, and if this happens without a specific reason, consult your doctor.
  • Avoid infections that may frequently occur by maintaining good hygiene if you have an issue of frequent bowel movements.
  • Avoid eating fibre-containing foods, nuts and caffeine that make you feel like defecating.
  • Stay calm and do not smoke or drink alcohol, as it can worsen your condition.
  • Contract specific muscles near the anus that help to stop releasing the stool.
  • Try to stand or lie down instead of sitting for long hours if you have defecation urgency.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.

What if I have taken an overdose of Rifagrap-M Tablet 10's

Give Rifagrap-M Tablet 10's only as advised by the physician. Do not exceed the prescribed dose, as it might cause an overdose. If you suspect you have given an overdose, seek immediate medical attention.

Drug Warnings

Avoid giving Rifagrap-M Tablet 10's to your child if she/he is allergic to it. Keep your Pediatrician informed about your child’s health condition, including their previous medications and medical history, to rule out any side effects/interactions. Before administration, inform the pediatrician about all the OTC medicines, including other vitamin supplements that your child is taking. It is advised not to give more than the prescribed dose of medicine. Also, inform your doctor if your child has a history of heart, liver/kidney disorder, colitis, blood dyscrasias, or neurologic toxicity before administration. 

Drug-Drug Interactions

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MetronidazoleDisulfiram
Critical
MetronidazoleAmprenavir
Critical

Drug-Drug Interactions

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MetronidazoleDisulfiram
Critical
How does the drug interact with Rifagrap-M Tablet:
Coadministration of Disulfiram with Rifagrap-M Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Rifagrap-M Tablet and Disulfiram together is generally avoided as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience sudden dizziness, confusion, weakness, shortness of breath, or palpitations, contact your doctor. Do not discontinue any medications without consulting a doctor.
MetronidazoleAmprenavir
Critical
How does the drug interact with Rifagrap-M Tablet:
Co-administration of Amprenavir with Rifagrap-M Tablet can increase the risk or severity of side effects.

How to manage the interaction:
Taking Rifagrap-M Tablet with Amprenavir is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience throbbing in the head and neck, throbbing headache, difficulty breathing, nausea, vomiting, sweating, thirst, chest pain, rapid heartbeat, palpitation, low blood pressure, dizziness, lightheadedness, blurred vision, and confusion, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MetronidazoleEthanol
Critical
How does the drug interact with Rifagrap-M Tablet:
Drinking alcohol while taking Rifagrap-M Tablet can increase the risk or severity of side effects.

How to manage the interaction:
Taking Rifagrap-M Tablet with Ethanol is avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience flushing, throbbing in head and neck, throbbing headache, difficulty breathing, nausea, vomiting, sweating, thirst, chest pain, rapid heartbeat, palpitation, low blood pressure, dizziness, lightheadedness, blurred vision, and confusion, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
RifaximinCholera, live attenuated
Severe
How does the drug interact with Rifagrap-M Tablet:
Coadministration of cholera vaccine with Rifagrap-M Tablet may reduce the effect of the cholera vaccine.

How to manage the interaction:
Taking Rfaximine and Cholera, live attenuated together can result in an interaction, but it can be taken together if prescribed by a doctor. It is recommended to take the cholera vaccine at least 14 days following the last dosage of Rifagrap-M Tablet. Do not discontinue any medicine without consulting a doctor.
MetronidazoleBusulfan
Severe
How does the drug interact with Rifagrap-M Tablet:
Coadministration of Busulfan and Rifagrap-M Tablet may increase the risk of side effects.

How to manage the interaction:
Taking Rifagrap-M Tablet and Busulfan together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience unusual bruising or bleeding, fever, diarrhea, sore throat, muscle aches, shortness of breath, or burning during urination, contact a doctor immediately. Do not discontinue the medication without a doctor's advice.
MetronidazoleMebendazole
Severe
How does the drug interact with Rifagrap-M Tablet:
Coadministration of Rifagrap-M Tablet with mebendazole may increase the risk or severity of side effects.

How to manage the interaction:
Although there is a possible interaction between Rifagrap-M Tablet and mebendazole, they can be taken together if your doctor has prescribed them. However, if you experience any unusual symptoms like fever, body ache, painful red rash, cough, peeling of the skin, or Drooling, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
MetronidazoleWarfarin
Severe
How does the drug interact with Rifagrap-M Tablet:
Coadministration of Rifagrap-M Tablet with warfarin can increase the risk of bleeding.

How to manage the interaction:
There is a possible interaction between Rifagrap-M Tablet and warfarin, but they can be taken together if a doctor has prescribed them. Consult a doctor if experience unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not stop using any medications without talking to a doctor.
MetronidazoleFluconazole
Moderate
How does the drug interact with Rifagrap-M Tablet:
Co-administration of Fluconazole together with Rifagrap-M Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
-Taking Rifagrap-M Tablet with Fluconazole together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid spicy or greasy foods that could upset the stomach.
  • Serve smaller, more frequent meals to help prevent stomach discomfort.
  • Limit foods high in fiber if the child has diarrhea to avoid worsening symptoms.
  • Include probiotics to support healthy digestion.
  • Avoid sugary drinks and junk food, as these can worsen stomach issues or irritate the gut.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS
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Alcohol

Not applicable

-

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Pregnancy

Not applicable

-

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Breast Feeding

Not applicable

-

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Driving

Not applicable

-

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Liver

Caution

If your child is suffering from liver disease, inform your doctor before using Rifagrap-M Tablet 10's.

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Kidney

Caution

If your child is suffering from kidney disease, inform your doctor before using Rifagrap-M Tablet 10's.

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Children

Safe if prescribed

Rifagrap-M Tablet 10's should be used for children in dose and duration as advised by the doctor.

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Heart

If your child has any heart disease, please consult a doctor before giving Rifagrap-M Tablet 10's.

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Geriatrics

Not applicable

Rifagrap-M Tablet 10's is for paediatric patients only.

FAQs

Rifagrap-M Tablet 10's is an antibiotic used to treat bacterial infections, particularly those affecting the gastrointestinal tract, such as traveler's diarrhea, Small Intestinal Bacterial Overgrowth and irritable bowel syndrome.

Rifagrap-M Tablet 10's is a combination of Metronidazole and Rifaximin. Metronidazole is an antimicrobial agent that kills bacteria and protozoa by disrupting their DNA. Rifaximin is a non-absorbable antibiotic that works directly in the gut to inhibit bacterial growth. Together, they help relieve symptoms, prevent complications, and promote intestinal health.

Consult your doctor before giving Rifagrap-M Tablet 10's with other antibiotics to avoid drug interactions.

Giving higher amounts than prescribed to children is ineffective and may lead to negative effects. To ensure safe and effective use, follow your doctor's dosage instructions.

You are not recommended to stop giving Rifagrap-M Tablet 10's to your child without consulting the doctor as it may worsen the condition or cause recurring symptoms. Therefore, use Rifagrap-M Tablet 10's for as long as your doctor has prescribed it, and if your child experiences any difficulty while taking Rifagrap-M Tablet 10's, please consult your doctor.

Common side effects include nausea, headache, dizziness, metallic taste, and diarrhea. If these side effects persist or worsen, seek immediate medical attention.

Country of origin

India

Manufacturer/Marketer address

Scf 1025, 1St & 2nd Floor, Motor Market, Manimajra, Chandigarh 160101, India
Other Info - RIF0287

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Reference

  1. https://pediazone.in/products/xifatic-m-suspension/
  2. https://www.drugs.com/metronidazole.html
  3. https://www.drugs.com/mtm/rifaximin.html

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