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  3. Rosufit CV 20 Capsule 15's

Rosufit CV 20 Capsule 15's, Pack of 15 CAPSULES
Rosufit CV 20 Capsule 15's, Pack of 15 CAPSULES
Rosufit CV 20 Capsule 15's, Pack of 15 CAPSULES
Rosufit CV 20 Capsule 15's, Pack of 15 CAPSULES
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Rosufit CV 20 Capsule is a combination medication that contains Rosuvastatin (a statin) and Clopidogrel (an antiplatelet). It helps prevent heart attacks, strokes, and chest pain (angina) by lowering bad cholesterol and fats in the blood and preventing blood clots. Common side effects may include headache, nausea, ankle swelling, and a slow heartbeat. Take this medicine exactly as prescribed. Tell your doctor if you have liver problems, bleeding issues, or if you're pregnant, breastfeeding, or taking other blood thinners. Avoid drinking alcohol while on this medication.

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Composition :

CLOPIDOGREL-75MG + ROSUVASTATIN-20MG

Manufacturer/Marketer :

Ajanta Pharma Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Rosufit CV 20 Capsule

Rosufit CV 20 Capsule is a combination of two types of medicines: a statin and an antiplatelet. It is used to help prevent heart attacks, strokes, and chest pain (angina) in people who are at high risk of heart problems. A heart attack happens when the coronary arteries, blood vessels that supply blood and oxygen to the heart, become blocked by fatty deposits (plaques), including cholesterol. These plaques narrow the arteries, leading to atherosclerosis and coronary artery disease, which are the leading causes of most heart attacks.

Rosufit CV 20 Capsule contains two active ingredients that work together to protect your heart. Rosuvastatin lowers cholesterol production in the liver. It reduces bad cholesterol (LDL) and triglycerides (TG) while increasing good cholesterol (HDL). Clopidogrel is an antiplatelet medicine (blood thinner) that prevents blood cells (platelets) from clumping together and forming clots. Together, these medicines improve blood flow and reduce the risk of blocked arteries, helping prevent serious heart and brain complications.

Take Rosufit CV 20 Capsule exactly as prescribed by your doctor, usually once a day with or without food. Do not skip doses or stop taking the medicine without consulting a doctor. Common side effects may include headache, nausea, dizziness, swollen ankles (oedema), and in rare cases, slow heart rate. Most side effects are mild and go away on their own, but contact your doctor if they persist or worsen. If you miss a dose, take it as soon as you remember. If it’s almost time for your next dose, skip the missed one. Do not take two doses at the same time.

Do not stop taking Rosufit CV 20 Capsule without consulting your doctor, as stopping it suddenly may increase your risk of heart attack or stroke. Please inform your doctor of any medical conditions or allergies you may have before starting Rosufit CV 20 Capsule . Always inform your doctor that you are taking Rosufit CV 20 Capsule before any surgery or if a new medicine is prescribed. Rosufit CV 20 Capsule should not be used during pregnancy or breastfeeding, as it may harm the baby. It is also not recommended for use in children below 10 years.

Uses of Rosufit CV 20 Capsule

Rosufit CV 20 Capsule is used to reduce the risk of serious heart and blood vessel problems in people at high risk of cardiovascular disease. It is commonly prescribed for:

  • Prevention of heart attacks: It helps lower LDL (bad) cholesterol and reduces the formation of blood clots that could block the coronary arteries.
  • Prevention of strokes: It improves blood flow to the brain and decreases the risk of clot-related (thrombotic) events.
  • Management of chest pain (angina): It enhances the blood supply to the heart muscles, relieving chest pain and discomfort caused by reduced blood flow.
  • Slowing the progression of atherosclerosis: It reduces the buildup of cholesterol and plaque in blood vessels, helping to maintain healthy arteries.
  • Secondary prevention of cardiovascular events: It is used in people who have already had a heart attack, stroke, or undergone heart procedures such as angioplasty or bypass surgery to help prevent future events.

Directions for Use

  • Take Rosufit CV 20 Capsule with or without food as advised by your doctor.
  • It is recommended to follow your doctor’s recommendations regarding the dosage and duration.
  • Swallow it as a whole with a glass of water.
  • Do not crush, chew or break it.

Medicinal Benefits

  • Rosufit CV 20 Capsule effectively reduces the risk of heart attacks and strokes by lowering bad cholesterol and preventing blood clots.
  • Slows the progression of atherosclerosis, helping keep arteries open and reducing cardiovascular strain.
  • Provides dual protection. Rosuvastatin stabilises cholesterol plaques, while Clopidogrel prevents clot formation on them.
  • Improves long-term cardiovascular outcomes in patients with coronary artery disease or those who’ve had angioplasty or bypass surgery.
  • Lowers the chance of future cardiovascular events in high-risk individuals or those with a history of heart attack or stroke.

How Rosufit CV 20 Capsule Works

Rosufit CV 20 Capsule is a combination of two medications, Rosuvastatin and Clopidogrel, used to reduce the risk of heart attack, stroke, and other cardiovascular events. Rosuvastatin is a statin that lowers cholesterol by inhibiting the HMG-CoA reductase enzyme, thereby reducing levels of LDL (bad cholesterol) and triglycerides while increasing HDL (good cholesterol). Clopidogrel is an antiplatelet agent that prevents blood platelets from clumping together, helping to reduce the risk of harmful blood clots. Together, they work to manage high cholesterol and prevent clot-related complications, offering comprehensive protection against serious heart and blood vessel conditions.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Rosufit CV 20 Capsule

Do not take more than the prescribed dose. Using more medication will not improve your symptoms; rather, they may cause poisoning or serious side effects. If you suspect that you may have overdosed of Rosufit CV 20 Capsule or if you experience any adverse events, please go to the emergency department of the closest hospital.

Drug Warnings

  • Do not take Rosufit CV 20 Capsule if you are allergic to any of its ingredients.
  • Do not use Rosufit CV 20 Capsule if you are pregnant, planning to become pregnant, or breastfeeding, as Rosuvastatin may harm the unborn baby and is strictly contraindicated during pregnancy.
  • Avoid Rosufit CV 20 Capsule if you have active liver disease or any active bleeding conditions, such as stomach ulcers or brain haemorrhage, unless specifically advised by your doctor.
  • Inform your doctor about all medications you are taking, especially antibiotics (like clarithromycin), antifungals (like itraconazole), HIV medicines, or blood thinners like warfarin, due to the risk of serious interactions.
  • Tell your doctor you are taking Rosufit CV 20 Capsule before any surgery or if a new medicine is being prescribed, to avoid potential complications or interactions.
  • Do not stop taking Rosufit CV 20 Capsule suddenly without medical advice, as this may increase the risk of heart attack, stroke, or other serious cardiovascular events.

Drug-Drug Interactions

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ClopidogrelSelexipag
Critical
ClopidogrelMifepristone
Critical

Drug-Drug Interactions

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ClopidogrelSelexipag
Critical
How does the drug interact with Rosufit CV 20 Capsule:
When Selexipag and Rosufit CV 20 Capsule are taken together, the body's ability to break down Selexipag may be reduced.

How to manage the interaction:
Taking Rosufit CV 20 Capsule with Selexipag is not recommended, please consult your doctor before taking it. They can be taken if prescribed by your doctor.
ClopidogrelMifepristone
Critical
How does the drug interact with Rosufit CV 20 Capsule:
Taking Rosufit CV 20 Capsule together with mifepristone increases the risk of vaginal bleeding in women.

How to manage the interaction:
Although taking Rosufit CV 20 Capsule with mifepristone is not recommended, that would certainly result in interaction, it can be taken if a doctor prescribes it. If you experience prolonged and heavy bleeding, consult a doctor immediately. Do not discontinue any medication without consulting a doctor.
ClopidogrelDeferasirox
Severe
How does the drug interact with Rosufit CV 20 Capsule:
Taking deferasirox together with Rosufit CV 20 Capsule may increase the risk of gastrointestinal ulcers and bleeding.

How to manage the interaction:
Although taking Rosufit CV 20 Capsule together with Deferasirox has a possibility of interaction, it can be taken if prescribed by your doctor. However, if you experience abdominal pain, bloating, dizziness, lightheadedness, red or black, tarry stools oe headache. Do not discontinue any medication without consulting your doctor.
ClopidogrelCangrelor
Severe
How does the drug interact with Rosufit CV 20 Capsule:
Co-administration of Cangrelor with Rosufit CV 20 Capsule and reduce its effectiveness if used at the same time.

How to manage the interaction:
Although taking Rosufit CV 20 Capsule with cangrelor can result in an interaction, they can be taken together if prescribed by a doctor. Rosufit CV 20 Capsule should be taken after the Cangrelor infusion is complete. Do not stop taking any medication without consulting a doctor.
ClopidogrelAcalabrutinib
Severe
How does the drug interact with Rosufit CV 20 Capsule:
Taking Rosufit CV 20 Capsule with acalabrutinib may increase the risk of bleeding.

How to manage the interaction:
There could be a possible interaction between Rosufit CV 20 Capsule and Acalabrutinib, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience any unusual bleeding or have other signs of bleeding, like feeling dizzy or lightheaded, red or black, sticky stools, or severe headaches. Do not discontinue any medication without consulting your doctor.
ClopidogrelPrasugrel
Severe
How does the drug interact with Rosufit CV 20 Capsule:
Taking Rosufit CV 20 Capsule together with Prasugrel will have an additive effect and increase the risk of bleeding.

How to manage the interaction:
Although taking Rosufit CV 20 Capsule together with Prasugrel may result in interaction, it can be taken if prescribed by a doctor. However, If you experience any unusual bleeding or have other signs of bleeding like feeling dizzy or lightheaded, red or black, sticky stools, or having a severe headache, consult a doctor immediately. Do not discontinue any medication without consulting a doctor.
ClopidogrelLoperamide
Severe
How does the drug interact with Rosufit CV 20 Capsule:
Taking loperamide with Rosufit CV 20 Capsule may significantly increase the blood levels of loperamide. This can lead to serious and complications such as irregular heart rhythm.

How to manage the interaction:
Although talking Rosufit CV 20 Capsule with loperamide may result in an interaction, it can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, or shortness of breath. Do not discontinue any medications without consulting a doctor.
ClopidogrelFluconazole
Severe
How does the drug interact with Rosufit CV 20 Capsule:
Co-administration of Rosufit CV 20 Capsule with fluconazole can reduce the effectiveness of Rosufit CV 20 Capsule.

How to manage the interaction:
Rosufit CV 20 Capsule and Fluconazole may interact, but you can take these medications together if a doctor has advised it. Do not stop using any medications without talking to your doctor.
ClopidogrelFluvoxamine
Severe
How does the drug interact with Rosufit CV 20 Capsule:
Taking fluvoxamine can lower the levels of Rosufit CV 20 Capsule in the blood, which can result in a decreased effectiveness of Rosufit CV 20 Capsule.

How to manage the interaction:
Taking Rosufit CV 20 Capsule and Fluvoxamine together possibly has an interaction, but you can take these medications together if your doctor has advised it. However, if you experience shortness of breath, dizziness, loss of balance, or trouble walking, consult your doctor immediately. Do not discontinue any medication without consulting your doctor.
ClopidogrelOmeprazole
Severe
How does the drug interact with Rosufit CV 20 Capsule:
When taken together omeprazole can lower the levels of Rosufit CV 20 Capsule in the blood, which can result in a decreased effectiveness of Rosufit CV 20 Capsule.

How to manage the interaction:
Taking omeprazole and Rosufit CV 20 Capsule together has an interaction, but you can take these medications together if a doctor has advised it. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Follow a Mediterranean or DASH diet rich in vegetables, fruits, whole grains, legumes, nuts, and healthy fats, such as olive oil, which has been shown to reduce the risk of cardiovascular events.
  • Limit your intake of saturated fats and eliminate trans fats to lower LDL cholesterol and reduce your risk of atherosclerosis.
  • Reduce sodium intake to less than 2,300 mg per day to help control blood pressure and lower the risk of stroke and heart disease.
  • Engage in at least 150 minutes of moderate aerobic exercise per week, such as brisk walking, swimming, or cycling, to improve heart health and cholesterol levels.
  • Quit smoking and avoid secondhand smoke exposure, as tobacco significantly increases the risk of clot formation and arterial damage.
  • Limit alcohol consumption to no more than one standard drink per day for women and two for men, as excessive alcohol raises blood pressure and cardiovascular risk.
  • Maintain a healthy weight (BMI 18.5–24.9); even modest weight loss improves cholesterol, blood pressure, and blood sugar control.
  • Manage blood sugar effectively, especially in patients with diabetes, to prevent accelerated vascular damage and cardiovascular complications.
  • Reduce chronic stress through techniques like mindfulness, relaxation, or yoga, and aim for 7–8 hours of quality sleep to support overall cardiovascular health.
  • Take medications like Rosuvastatin and Clopidogrel exactly as prescribed, and attend regular medical check-ups to monitor lipid levels, clotting function, and overall cardiovascular risk.

Habit Forming

No

Therapeutic Class

ANTICOAGULANT/ANTITHROMBOTIC

Rosufit CV 20 Capsule Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Rosufit CV 20 Capsule should not be taken with alcohol as it may worsen your liver condition with increased secretion of liver enzymes like transaminase. Keep your doctor informed if you drink alcohol.

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Pregnancy

Unsafe

Rosufit CV 20 Capsule contains Rosuvastatin, which is a pregnancy category X medicine. It may cause harm to both the pregnant mother and the fetus. Hence, it is not recommended for pregnant women and those who are planning for a pregnancy. Your doctor may prescribe it only in extreme cases.

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Breast Feeding

Caution

Take Rosufit CV 20 Capsule only when prescribed, it is known to pass on in a limited quantity via breast milk to the child.

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Driving

Caution

Drive with caution, Rosufit CV 20 Capsule usually causes blurry vision and may affect driving ability.

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Liver

Caution

Rosufit CV 20 Capsule to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Rosufit CV 20 Capsule to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

bannner image

Children

Caution

Rosufit CV 20 Capsule is not recommended for children below the age of 10 years. The safety and effectiveness of Rosufit CV 20 Capsule have not been established in children due to limited testing of Rosufit CV 20 Capsule on children by competent authorities worldwide.

Have a query?

FAQs

Rosufit CV 20 Capsule is used to prevent heart attacks and strokes in the future. It lowers the raised level of cholesterol and fats (triglycerides) in the body.

Rosufit CV 20 Capsule is composed of two medicines, namely: Rosuvastatin and Clopidogrel. Rosuvastatin is a lipid-lowering medication that inhibits the enzyme responsible for producing cholesterol in the body. As a result, it lowers the bad cholesterol (low-density lipoproteins or LDL) and triglycerides (TG), and increases the levels of good cholesterol (high-density lipoproteins or HDL). Clopidogrel is a blood thinner (anticoagulant) that collectively prevents the formation of clots in the blood vessels. Together, Rosufit CV 20 Capsule reduces the increased levels of bad cholesterol (low-density lipoprotein and triglycerides) and prevents blood clots, thereby reducing the risk of heart attack, stroke, and heart-related chest pain (angina).

Yes, Rosufit CV 20 Capsule contains clopidogrel that prevents blood clotting. It works by preventing platelets (a type of blood cell) from sticking together and forming clots, thereby preventing heart attacks and strokes.

No, Rosufit CV 20 Capsule contains Rosuvastatin, pregnancy category X medicine, and can harm both pregnant mother and unborn baby. Even if you are planning for pregnancy, tell your doctor that you are using Rosufit CV 20 Capsule .

If you accidentally take an overdose of Rosufit CV 20 Capsule , you may have liver problems (increased secretion of liver enzymes) and bleeding complications. If problems persist, please go to the nearest clinic or hospital immediately.

It would be best if you had total lipid profile (TG, HDL, LDL, VLDL, TC) and Blood coagulation tests like Complete blood count (CBC), Factor V assay, Fibrinogen Test, Prothrombin time (PT or PT-INR), Platelet count, Thrombin time and Bleeding time to analyze your blood clot timing and cholesterol level.

Do not drink grapefruit juice while taking Rosufit CV 20 Capsule . Grapefruit juice may increase the blood-thinning effect of your medicine.

Yes, prolonged use of Rosufit CV 20 Capsule may cause muscle diseases like myopathy and rhabdomyolysis. So if you feel any musculoskeletal pain after taking Rosufit CV 20 Capsule , consult your doctor about this issue.

Yes, taking Rosufit CV 20 Capsule can increase bleeding risk as it contains aspirin and clopidogrel, which belong to a class of blood-thinning agents. Therefore, please exercise caution when shaving, cutting fingernails or toenails, or using sharp objects to prevent bleeding. Before undergoing any surgical procedure, please inform your doctor that you are taking Rosufit CV 20 Capsule .

Consult your doctor before taking other medications while on treatment with Rosufit CV 20 Capsule to prevent any potential interactions. Let the doctor know if you are taking antibiotics, anti-HIV drugs, antifungal, blood thinners, anti-arthritis medicines, oral contraceptives, cardiac medicines or immunosuppressants.

If you are due to undergo any surgery or dental procedure, inform the doctor that you are taking Rosufit CV 20 Capsule . The doctor might ask you to stop Rosufit CV 20 Capsule before surgery as it might increase the risk of bleeding.

Follow a healthy diet and exercise regularly. Avoid smoking and alcohol consumption. Manage stress by doing meditation. Be cautious while using sharp objects.

It might be safe to use paracetamol while taking Rosufit CV 20 Capsule as other painkillers may increase the risk of bleeding. However, consult the doctor before using any painkiller medicines.

Side effects of Rosufit CV 20 Capsule include headaches, ankle swelling due to fluid retention (oedema), slow heart rate, and nausea. If the side effects are persistent, reach out to your doctor.

Country of origin

India

Manufacturer/Marketer address

Ajanta House, Charkop, Kandivli West, Mumbai 400 067, India
Other Info - ROS0775

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 25, 2025 | 8:21 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.nhs.uk/medicines/clopidogrel/
  2. https://www.drugs.com/uk/pdf/leaflet/1052686.pdf
  3. https://medlineplus.gov/druginfo/meds/a603033.html#:~:text=Rosuvastatin%20is%20in%20a%20class,other%20parts%20of%20the%20body.

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