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compositionComposition:CLOPIDOGREL-75MG+ROSUVASTATIN-20MG
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Prescription Medicine
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STATPURE-CV 20MG CAPSULES is a combination medication that contains Rosuvastatin (a statin) and Clopidogrel (an antiplatelet). It helps prevent heart attacks, strokes, and chest pain (angina) by lowering bad cholesterol and fats in the blood and preventing blood clots. Common side effects may include headache, nausea, ankle swelling, and a slow heartbeat. Take this medicine exactly as prescribed. Tell your doctor if you have liver problems, bleeding issues, or if you're pregnant, breastfeeding, or taking other blood thinners. Avoid drinking alcohol while on this medication.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

CLOPIDOGREL-75MG+ROSUVASTATIN-20MG

Manufacturer/Marketer :

Mankind Pharma Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About STATPURE-CV 20MG CAPSULES

STATPURE-CV 20MG CAPSULES is a prescription medication used to lower the risk of heart attacks, strokes, and blood clots in individuals with existing heart disease. It combines two active medicines that work together to keep your blood vessels clear and prevent dangerous blockages. This medicine is typically prescribed after a recent heart event or procedure, such as getting a stent.

You should take STATPURE-CV 20MG CAPSULES exactly once a day, at the same time every day, to ensure it works effectively in your body. It can be taken with or without food, though taking it with food may help prevent an upset stomach. Combining this medication with a heart-healthy diet, regular physical activity, and avoiding smoking will significantly improve your long-term results.

While taking STATPURE-CV 20MG CAPSULES , you might experience mild side effects such as an upset stomach, mild muscle aches, or bruising more easily than usual. However, you must contact your doctor immediately if you experience severe muscle pain, dark-coloured urine, unusual or uncontrollable bleeding, or signs of liver damage such as yellowing of your skin or eyes.

Do not take this if you have active liver disease or active bleeding such as a stomach ulcer. Patients with significant kidney impairment may require special monitoring and dose adjustments, and should use this medicine only under medical supervision. Before starting STATPURE-CV 20MG CAPSULES , tell your doctor if you have a history of liver or kidney disease, thyroid problems, or if you regularly drink alcohol.

This medicine can interact with certain pain relievers, other blood thinners, and some foods or beverages. Be sure to tell your doctor about all medicines, supplements, and dietary habits so potential interactions can be reviewed. If you are pregnant, planning to become pregnant, breastfeeding, or are over the age of 70, you must consult your doctor before using STATPURE-CV 20MG CAPSULES , as it may not be safe for you.

Uses of STATPURE-CV 20MG CAPSULES

STATPURE-CV 20MG CAPSULES is prescribed to reduce the risk of serious cardiovascular events by lowering cholesterol levels and preventing harmful blood clot formation. Its uses include:

  • Prevention of heart attacks: It prevents blood clots from forming in your arteries and lowers cholesterol to keep blood flowing smoothly to your heart.
  • Prevention of stroke: By stopping blood cells from sticking together and reducing plaque buildup, it reduces the risk of a clot blocking blood flow to your brain.
  • Management of acute coronary syndrome: It helps protect patients who have recently experienced chest pain or a heart attack from having another cardiovascular event.
  • Protection after stent placement: It keeps newly placed coronary stents open and clear of blood clots.
     

Key Benefits

When taken as prescribed, STATPURE-CV 20MG CAPSULES offers several important benefits for cardiovascular health and long-term protection, including:

  • Dual-action cardiovascular protection: STATPURE-CV 20MG CAPSULES combines cholesterol-lowering and antiplatelet effects in a single tablet, helping protect against heart attacks and strokes.
  • Improved treatment convenience: By combining two medicines into one pill, it reduces the number of medications you need to take each day, making it easier to follow your treatment plan.
  • Reduced risk of recurrent cardiovascular events: It significantly lowers the risk of experiencing another heart attack, stroke, or other serious cardiovascular complication.
  • Support for healthy blood circulation: By helping keep blood vessels open and reducing plaque buildup, it promotes smoother blood flow throughout the body.
  • Long-term heart and vascular health: Regular use helps protect blood vessels from further damage, supporting overall cardiovascular function and physical well-being.
     
Side effects of Statpure-CV 20 Capsule
Here are the step-by-step strategies to manage the side effects of " Muscle Pain" caused by medication usage:
  • Report to Your Doctor: Inform your doctor about the muscle pain, as they may need to adjust your medication.
  • Stretch Regularly: Gentle stretching can help relieve muscle pain and stiffness.
  • Stay Hydrated: Adequate water intake supports muscle health by removing harmful substances and maintaining proper muscle function.
  • Warm or Cold Compresses: Apply cold or warm compresses to the affected area to reduce pain and inflammation.
  • Rest and Relaxation: Adequate rest helps alleviate muscle strain, while relaxation techniques like deep breathing and meditation can soothe muscle tightness, calm the mind, and promote relief from discomfort.
  • Gentle Exercise: Participate in low-impact activities, such as yoga or short walks, to improve flexibility, reduce muscle tension, and alleviate discomfort.
  • Consult a physician: If your symptoms don't improve or get worse, go to the doctor for help and guidance.
Here are the steps to manage Joint Pain caused by medication usage:
  • Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
  • Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
  • Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
  • Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Directions for Use

To get the maximum benefit from STATPURE-CV 20MG CAPSULES and reduce the risk of cardiovascular complications, it is important to take the medication exactly as prescribed by your doctor.

  • Swallow the tablet whole: Take the tablet with a full glass of water. Do not crush, chew, or break it unless your doctor or pharmacist advises otherwise, as this may affect how the medicine works.
  • Take it at the same time each day: Maintaining a consistent dosing schedule helps keep a steady level of the medication in your body and improves its effectiveness.
  • Can be taken with or without food: You may take STATPURE-CV 20MG CAPSULES either on an empty stomach or with meals, according to your preference or your doctor's advice.
  • Follow your doctor's instructions carefully: Always take the medication exactly as prescribed and attend any recommended follow-up appointments.
  • Do not stop treatment suddenly: Even if you feel well, do not discontinue STATPURE-CV 20MG CAPSULES without consulting your doctor, as stopping it abruptly may increase your risk of heart attack, stroke, or blood clot formation.
  • If you miss a dose: Take it as soon as you remember. However, if it is nearly time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.
     

How STATPURE-CV 20MG CAPSULES Works

How STATPURE-CV 20MG CAPSULES Works? STATPURE-CV 20MG CAPSULES protects your heart and blood vessels through two complementary mechanisms: Rosuvastatin belongs to a group of medicines called statins. It works in the liver by blocking an enzyme called HMG-CoA reductase, which is required for cholesterol production. This lowers levels of low-density lipoprotein (LDL or 'bad' cholesterol) and triglycerides in the blood while helping to stabilise existing fatty plaques within the arteries, reducing the risk of plaque rupture. Clopidogrel is an antiplatelet medicine that helps prevent blood platelets from sticking together and forming harmful blood clots. By reducing clot formation inside blood vessels, it helps maintain healthy blood flow and lowers the risk of heart attack and stroke. Together, these two medicines help keep arteries open, reduce plaque progression, and decrease the likelihood of dangerous cardiovascular events.
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Alcohol

Unsafe

STATPURE-CV 20MG CAPSULES should not be taken with alcohol as it may worsen your liver condition with increased secretion of liver enzymes like transaminase. Keep your doctor informed if you drink alcohol.

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Pregnancy

Unsafe

STATPURE-CV 20MG CAPSULES contains Rosuvastatin, which is a pregnancy category X medicine. It may cause harm to both the pregnant mother and the fetus. Hence, it is not recommended for pregnant women and those who are planning for a pregnancy. Your doctor may prescribe it only in extreme cases.

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Breast Feeding

Caution

Take STATPURE-CV 20MG CAPSULES only when prescribed, it is known to pass on in a limited quantity via breast milk to the child.

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Driving

Caution

Drive with caution, STATPURE-CV 20MG CAPSULES usually causes blurry vision and may affect driving ability.

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Liver

Caution

STATPURE-CV 20MG CAPSULES to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

STATPURE-CV 20MG CAPSULES to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Caution

STATPURE-CV 20MG CAPSULES is not recommended for children below the age of 10 years. The safety and effectiveness of STATPURE-CV 20MG CAPSULES have not been established in children due to limited testing of STATPURE-CV 20MG CAPSULES on children by competent authorities worldwide.

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Heart

Safe if prescribed

STATPURE-CV 20MG CAPSULES can be used in heart patients if prescribed by the physician to reduce the risk of heart attack and stroke. Please consult your physician if you have any concerns.

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Geriatrics

Consult your doctor

STATPURE-CV 20MG CAPSULES should be used in elderly people only if prescribed by the physician.

What if I have taken an overdose of STATPURE-CV 20MG CAPSULES

Do not take more than the prescribed dose. Using more medication will not improve your symptoms; rather, they may cause poisoning or serious side effects. If you suspect that you may have overdosed of STATPURE-CV 20MG CAPSULES or if you experience any adverse events, please go to the emergency department of the closest hospital.

Diet & Lifestyle Advise

  • Follow a heart-healthy diet: Focus on eating foods low in saturated fats, trans fats, and cholesterol. Increase your intake of soluble fibre, fresh vegetables, fruits, and whole grains.
  • Grapefruit and grapefruit juice: Grapefruit interactions are much more significant with certain statins that are metabolised through the CYP3A4 enzyme system. Rosuvastatin is minimally affected by grapefruit in most patients. Routine avoidance is generally not required, but you should consult your doctor or pharmacist if you regularly consume grapefruit or take multiple medications.
  • Incorporate regular, gentle exercise: Aim for at least 150 minutes of moderate-intensity exercise, like brisk walking, each week, as cleared by your doctor.
  • Limit alcohol consumption: Drinking alcohol can increase your risk of liver damage and stomach bleeding while taking this medicine.
  • Avoid smoking: Smoking damages blood vessels and increases the risk of blood clots, working against the benefits of this medicine.
  • Keep scheduled blood tests: Regular lipid profile testing and other laboratory monitoring help your healthcare provider assess how well the medication is working. 
     
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How Soon It Starts Working

The time required for STATPURE-CV 20MG CAPSULES to start to work: STATPURE-CV 20MG CAPSULES ideally shows its action within 1 hour after administration. The time for which the effects of STATPURE-CV 20MG CAPSULES last: The effect of STATPURE-CV 20MG CAPSULES lasts for 24 hours.

What if you forget to take STATPURE-CV 20MG CAPSULES

If you miss a dose of STATPURE-CV 20MG CAPSULES , take it as soon as you remember. However, if it is almost time for the next dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for the missed one.

Storage

Store STATPURE-CV 20MG CAPSULES at room temperature, between 20°C to 25°C (68°F to 77°F). •Keep the medication in its original packaging or container to protect it from moisture and direct light.

Drug Warnings

  • Inform all healthcare providers: Tell any doctor, dentist, or surgeon that you are taking STATPURE-CV 20MG CAPSULES before scheduling any medical or dental procedures, as you may need to stop taking it temporarily to prevent excess bleeding.
  • Watch for signs of bleeding: Be cautious when using sharp objects, shaving, or brushing your teeth. Use a soft-bristled toothbrush and an electric razor to minimize the risk of cuts.
  • Monitor for muscle pain: Pay close attention to any unexplained muscle aches or weakness, and report them to your doctor immediately, especially if accompanied by a fever or dark-coloured urine.
  • Avoid self-medicating for pain: Do not take nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or naproxen without asking your doctor first, as they can significantly increase your risk of stomach bleeding.
  • Do not stop taking suddenly: Stopping this medication abruptly can greatly increase your risk of a heart attack or stroke. Always consult your doctor before making any changes.
  • Individual response may vary: Some people process clopidogrel differently due to genetic factors. In certain situations, your doctor may recommend additional testing or alternative treatment options to ensure adequate protection against blood clots.
  • Attend regular follow-up appointments: Your doctor may periodically monitor your cholesterol levels, liver function, kidney function, and overall cardiovascular health to ensure the medication remains safe and effective.
  • Do not allow your medication supply to run out: Because sudden interruption of treatment may increase the risk of heart attack, stroke, or blood clot formation, refill your prescription before your current supply is exhausted. 
     

Drug-Drug Interactions

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Drug-Drug Interactions

Before taking STATPURE-CV 20MG CAPSULES , inform your doctor about all medications, supplements, and herbal products you use, as several medicines can increase the risk of side effects or alter how this combination works.

  • Blood thinners (like warfarin): Combining STATPURE-CV 20MG CAPSULES with anticoagulants can significantly increase the risk of bleeding and bruising.
  • Nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen: Taking these medicines together may increase the risk of stomach irritation, ulcers, and gastrointestinal bleeding.
  • Certain antidepressants (such as SSRIs): These medications can further increase the risk of bleeding when used alongside clopidogrel.
  • HIV, hepatitis C, or antifungal medications: Some of these medicines can increase rosuvastatin levels in the body, raising the risk of muscle damage and other side effects.
  • Certain stomach acid medicines (such as omeprazole): Some medicines can reduce the activation of clopidogrel in the body, potentially making it less effective. Always check with your doctor before starting new medications. 

Drug-Food Interactions

Certain foods and beverages may affect the safety or effectiveness of STATPURE-CV 20MG CAPSULES . Keep the following precautions in mind:

  • Grapefruit and grapefruit juice: Grapefruit interactions are much more significant with certain statins that are metabolised through the CYP3A4 enzyme system. Rosuvastatin is minimally affected by grapefruit in most patients. Routine avoidance is generally not required, but patients should consult their doctor or pharmacist if they regularly consume grapefruit or take multiple medications.
  • Excessive alcohol consumption: Drinking large amounts of alcohol may increase the risk of liver problems and should be avoided or limited while taking this medication.

Drug-Disease Interactions

Certain medical conditions can affect whether STATPURE-CV 20MG CAPSULES is suitable for you. Make sure your healthcare provider is aware of your complete medical history before starting treatment.

  • Active liver disease: This medication should not be used in patients with active liver disease, as it may worsen liver function.
  • Kidney impairment: Patients with moderate to severe kidney disease may require dose adjustments and closer monitoring, particularly because rosuvastatin exposure can increase in severe renal impairment. Your doctor will determine the appropriate dose based on your kidney function.
  • Active internal bleeding: Conditions such as a bleeding stomach ulcer or other active bleeding disorders make this medication unsafe because clopidogrel reduces blood clotting.
  • Thyroid disorders: Patients with uncontrolled thyroid conditions may have a higher risk of muscle-related side effects associated with rosuvastatin.
  • History of muscle disorders: Individuals with previous muscle problems or statin-associated muscle symptoms should use this medication with caution and under medical supervision.
     
Clopidogrel + RosuvastatinSelexipag
Critical
Clopidogrel + RosuvastatinMifepristone
Critical

Drug-Drug Interactions

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Clopidogrel + RosuvastatinSelexipag
Critical
How does the drug interact with Statpure-CV 20 Capsule:
When Selexipag and Clopidogrel are taken together, the body's ability to break down Selexipag may be reduced.

How to manage the interaction:
Taking Clopidogrel with Selexipag is not recommended, please consult a doctor before taking it. They can be taken if prescribed by a doctor. Do not discontinue the medications without consulting a doctor.
Clopidogrel + RosuvastatinMifepristone
Critical
How does the drug interact with Statpure-CV 20 Capsule:
Co-administration of Clopidogrel together with Mifepristone increases the risk of vaginal bleeding in women.

How to manage the interaction:
Although taking Clopidogrel with Mifepristone is not recommended, that would certainly result in interaction, it can be taken if a doctor prescribes it. If you experience prolonged and heavy bleeding, consult a doctor immediately. Do not discontinue any medication without consulting a doctor.
Clopidogrel + RosuvastatinTirofiban
Severe
How does the drug interact with Statpure-CV 20 Capsule:
Coadministration of Tirofiban with Clopidogrel and Rosuvastatin can increase the risk of bleeding.

How to manage the interaction:
There may be a possibility of interaction between Tirofiban and Clopidogrel, but it can be taken if prescribed by a doctor. Do not discontinue any medications without consulting your doctor.
Clopidogrel + RosuvastatinRabeprazole
Severe
How does the drug interact with Statpure-CV 20 Capsule:
Taking Statpure-CV 20 Capsule with Rabeprazole can reduce the effectiveness of Clopidogrel.

How to manage the interaction:
Taking Statpure-CV 20 Capsule and Rabeprazole together possibly has an interaction, but you can take these medications together if a doctor has advised it. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Clopidogrel + RosuvastatinRivaroxaban
Severe
How does the drug interact with Statpure-CV 20 Capsule:
Co-administration of Clopidogrel with Rivaroxaban increases the risk of severe bleeding due to the additive effect.

How to manage the interaction:
Although taking Clopidogrel with Rivaroxaban may possibly result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience any unusual bleeding or have other signs of bleeding like feeling dizzy or lightheaded, red or black, sticky stools, coughing up or vomiting blood that looks like coffee grounds, or having a severe headache consult a doctor immediately. Do not discontinue any medication without consulting a doctor.
Clopidogrel + RosuvastatinFluvoxamine
Severe
How does the drug interact with Statpure-CV 20 Capsule:
Taking Fluvoxamine can lower the levels of Statpure-CV 20 Capsule in the blood, which can result in a decreased effectiveness of Clopidogrel.

How to manage the interaction:
Taking Statpure-CV 20 Capsule and Fluvoxamine together possibly has an interaction, but you can take these medications together if a doctor has advised it. However, if you experience chest pain, shortness of breath, fatigue, dizziness, loss of balance, or trouble walking, consult a doctor immediately. Do not discontinue any medication without consulting a doctor.
Clopidogrel + RosuvastatinPioglitazone
Severe
How does the drug interact with Statpure-CV 20 Capsule:
Taking Pioglitazone with Statpure-CV 20 Capsule can increase the blood levels of Pioglitazone, when these medicines are taken together, you may experience hypoglycemia (low blood sugar).

How to manage the interaction:
Taking Statpure-CV 20 Capsule together with Pioglitazone may possibly lead to interaction, but it can be taken if prescribed by a doctor. Consult a doctor immediately if you experience any symptoms like headache, dizziness, drowsiness, nervousness, weakness, shakings, nausea, hunger, sweating, and palpitation. It is advised to maintain a blood sugar levels. Do not discontinue any medication without consulting the doctor.
Clopidogrel + RosuvastatinFondaparinux
Severe
How does the drug interact with Statpure-CV 20 Capsule:
Taking Statpure-CV 20 Capsule together with Fondaparinux can increase the risk of bleeding.

How to manage the interaction:
There may be a possibility of interaction between Statpure-CV 20 Capsule and Fondaparinux, but they can be taken together if prescribed by a doctor. However, if you experience bleeding, severe back pain, dizziness, black or red stools, severe headache, weakness, and vomiting contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Clopidogrel + RosuvastatinAtazanavir
Severe
How does the drug interact with Statpure-CV 20 Capsule:
Co-administration of Statpure-CV 20 Capsule and Atazanavir can increase the blood levels of Rosuvastatin and can increase the risk of liver damage and rhabdomyolysis ( breakdown of skeletal muscle tissue).

How to manage the interaction:
Co-administration of Statpure-CV 20 Capsule and Atazanavir can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, dark-colored urine, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Clopidogrel + RosuvastatinRegorafenib
Severe
How does the drug interact with Statpure-CV 20 Capsule:
Co-administration of Regorafenib together with Clopidogrel may increase the risk of bleeding.

How to manage the interaction:
There may be a possibility of interaction between Clopidogrel and Regorafenib, but it can be taken if prescribed by a doctor. However, if you experience any unusual bleeding or have other signs of bleeding like feeling dizzy or lightheaded, red or black, sticky stools, coughing up or vomiting blood that looks like coffee grounds, or having a severe headache consult a doctor immediately. Do not discontinue any medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

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FAQs

STATPURE-CV 20MG CAPSULES is used to prevent heart attacks and strokes in the future. It lowers the raised level of cholesterol and fats (triglycerides) in the body.
STATPURE-CV 20MG CAPSULES is composed of two medicines, namely: Rosuvastatin and Clopidogrel. Rosuvastatin is a lipid-lowering medication that inhibits the enzyme responsible for producing cholesterol in the body. As a result, it lowers the bad cholesterol (low-density lipoproteins or LDL) and triglycerides (TG), and increases the levels of good cholesterol (high-density lipoproteins or HDL). Clopidogrel is a blood thinner (anticoagulant) that collectively prevents the formation of clots in the blood vessels. Together, STATPURE-CV 20MG CAPSULES reduces the increased levels of bad cholesterol (low-density lipoprotein and triglycerides) and prevents blood clots, thereby reducing the risk of heart attack, stroke, and heart-related chest pain (angina).
Yes, STATPURE-CV 20MG CAPSULES contains clopidogrel that prevents blood clotting. It works by preventing platelets (a type of blood cell) from sticking together and forming clots, thereby preventing heart attacks and strokes.
No, STATPURE-CV 20MG CAPSULES contains Rosuvastatin, pregnancy category X medicine, and can harm both pregnant mother and unborn baby. Even if you are planning for pregnancy, tell your doctor that you are using STATPURE-CV 20MG CAPSULES .
If you accidentally take an overdose of STATPURE-CV 20MG CAPSULES , you may have liver problems (increased secretion of liver enzymes) and bleeding complications. If problems persist, please go to the nearest clinic or hospital immediately.
It would be best if you had total lipid profile (TG, HDL, LDL, VLDL, TC) and Blood coagulation tests like Complete blood count (CBC), Factor V assay, Fibrinogen Test, Prothrombin time (PT or PT-INR), Platelet count, Thrombin time and Bleeding time to analyze your blood clot timing and cholesterol level.
Do not drink grapefruit juice while taking STATPURE-CV 20MG CAPSULES . Grapefruit juice may increase the blood-thinning effect of your medicine.
Yes, prolonged use of STATPURE-CV 20MG CAPSULES may cause muscle diseases like myopathy and rhabdomyolysis. So if you feel any musculoskeletal pain after taking STATPURE-CV 20MG CAPSULES , consult your doctor about this issue.
Yes, taking STATPURE-CV 20MG CAPSULES can increase bleeding risk as it contains aspirin and clopidogrel, which belong to a class of blood-thinning agents. Therefore, please exercise caution when shaving, cutting fingernails or toenails, or using sharp objects to prevent bleeding. Before undergoing any surgical procedure, please inform your doctor that you are taking STATPURE-CV 20MG CAPSULES .
Consult your doctor before taking other medications while on treatment with STATPURE-CV 20MG CAPSULES to prevent any potential interactions. Let the doctor know if you are taking antibiotics, anti-HIV drugs, antifungal, blood thinners, anti-arthritis medicines, oral contraceptives, cardiac medicines or immunosuppressants.
If you are due to undergo any surgery or dental procedure, inform the doctor that you are taking STATPURE-CV 20MG CAPSULES . The doctor might ask you to stop STATPURE-CV 20MG CAPSULES before surgery as it might increase the risk of bleeding.
Follow a healthy diet and exercise regularly. Avoid smoking and alcohol consumption. Manage stress by doing meditation. Be cautious while using sharp objects.
It might be safe to use paracetamol while taking STATPURE-CV 20MG CAPSULES as other painkillers may increase the risk of bleeding. However, consult the doctor before using any painkiller medicines.
Side effects of STATPURE-CV 20MG CAPSULES include headaches, ankle swelling due to fluid retention (oedema), slow heart rate, and nausea. If the side effects are persistent, reach out to your doctor.
It is highly recommended to limit or avoid alcohol while taking this medicine. Drinking alcohol regularly can increase your risk of liver damage and stomach bleeding. Talk to your doctor about what is safe for you.
Grapefruit has a well-known interaction with certain statins that are metabolised through the CYP3A4 enzyme system. Rosuvastatin is minimally affected by grapefruit in most patients, so routine avoidance is generally not required. However, if you regularly consume grapefruit or take multiple medications, you should consult your doctor or pharmacist to determine whether any dietary restrictions apply to you.
You should avoid taking nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or naproxen without consulting your healthcare provider. These pain relievers can significantly increase your risk of stomach ulcers and serious bleeding when combined with STATPURE-CV 20MG CAPSULES . Talk to your doctor for safe pain relief alternatives.
If you develop unexplained muscle pain, tenderness, or weakness—especially if you also have a fever or dark-coloured urine—contact your doctor immediately. This could be a sign of a rare but serious muscle condition. Talk to your doctor right away.
No, STATPURE-CV 20MG CAPSULES is not safe for use during pregnancy or while breastfeeding, as it can harm the developing baby. If you become pregnant or plan to become pregnant while taking this medicine, stop taking it and contact your healthcare provider immediately. Talk to your doctor for alternative options.
STATPURE-CV 20MG CAPSULES can be taken at any time of day, but it is best to take it at the same time every day to maintain a consistent level of medicine in your body. Some people prefer taking it in the evening, but you should follow your doctor's recommendation. Talk to your doctor or pharmacist for guidance.
STATPURE-CV 20MG CAPSULES is typically a long-term treatment designed to prevent serious heart events. Even if you feel perfectly healthy, you should continue taking it as prescribed. Stopping the medication early can increase your risk of heart attack or stroke. Talk to your doctor before making any changes.

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Country of origin

India

Manufacturer/Marketer address

208, Okhla Industrial Estate, Phase III, New Delhi - 110020.
Other Info - STA0728
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