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compositionComposition:FENTANYL-50MCG
prescriptionPrescription Medicine
Rufenyl 50 mcg Injection 2 ml is used to relieve pain. It contains Fentanyl which works by blocking a chemical messenger in the brain responsible for causing pain. In some cases, this medicine may cause side effects such as dizziness, sleepiness, increased or decreased blood pressure, and irregular heartbeat. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

FENTANYL-50MCG

Manufacturer/Marketer :

Rusan Healthcare Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

Rufenyl 50 mcg Injection 2 ml belongs to a class of drugs known as 'opioid analgesics,' primarily used to relieve pain. It is used to reduce pain before and after surgery. Pain can be temporary (acute) or long-lasting (chronic) in nature. Acute pain is caused by damage to the tissues of the muscle, bone, or other organs for a short time. Chronic pain lasts for a long duration and is caused due to pathologies like nerve damage and osteoarthritis.

Rufenyl 50 mcg Injection 2 ml contains Fentanyl, which is primarily used to treat pain. It works by blocking a chemical messenger in the brain responsible for causing pain. Hence, changing the way the brain and nervous system respond to pain.

Rufenyl 50 mcg Injection 2 ml will be administered to your vein by a trained healthcare professional; hence, do not self-administer. This medicine may cause certain common side effects such as dizziness, sleepiness, increased or decreased blood pressure, and irregular heartbeat in some cases. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently. 

Avoid receiving Rufenyl 50 mcg Injection 2 ml if you are allergic to it or opioids or any ingredients of Rufenyl 50 mcg Injection 2 ml.  Inform your doctor if you have respiratory disorders, heart diseases, high blood pressure, and liver or kidney disease before starting treatment with Rufenyl 50 mcg Injection 2 ml. Avoid consuming alcohol along with Rufenyl 50 mcg Injection 2 ml as it could lead to increased dizziness. Rufenyl 50 mcg Injection 2 ml should not be used for a prolonged time, as it may lead to mental or physical dependence on Rufenyl 50 mcg Injection 2 ml. Using MAO inhibitor medicine along with Rufenyl 50 mcg Injection 2 ml may lead to serious side effects. Hence inform your doctor if you are using any such medicine. Blood pressure and cardiovascular (heart) status should be monitored closely during the treatment with Rufenyl 50 mcg Injection 2 ml, especially in people affected with high blood pressure and a history of heart failure. Rufenyl 50 mcg Injection 2 ml is not recommended for children below 18 years of age.

Uses of Rufenyl 50 mcg Injection 2 ml

Rufenyl 50 mcg Injection 2 ml is used in the treatment of Pain relief. The detailed uses of Rufenyl 50 mcg Injection 2 ml are as follows:

  • Severe Chronic Pain: Rufenyl 50 mcg Injection 2 ml is used to treat severe chronic pain.
  • Postoperative Pain: Rufenyl 50 mcg Injection 2 ml helps in the treatment of postoperative pain.

Key Benefits

Rufenyl 50 mcg Injection 2 ml belongs to a class of drugs known as 'opioid analgesics,' containing Fentanyl, primarily used to relieve pain. It is used to treat breakthrough pain (sudden episodes of pain occurring despite treatment with pain medication) in cancer patients. It is also used as an anaesthetic agent for short operations and relieves pain in conditions like rheumatoid arthritis and osteoarthritis and pain affecting the joints and muscles. It works by blocking a chemical messenger in the brain responsible for causing pain. Hence, changing the way the brain and nervous system respond to pain.

Side effects of Rufenyl 50 mcg Injection 2 ml
Here are the step-by-step strategies to manage the side effects of " Muscle Pain" caused by medication usage:
  • Report to Your Doctor: Inform your doctor about the muscle pain, as they may need to adjust your medication.
  • Stretch Regularly: Gentle stretching can help relieve muscle pain and stiffness.
  • Stay Hydrated: Adequate water intake supports muscle health by removing harmful substances and maintaining proper muscle function.
  • Warm or Cold Compresses: Apply cold or warm compresses to the affected area to reduce pain and inflammation.
  • Rest and Relaxation: Adequate rest helps alleviate muscle strain, while relaxation techniques like deep breathing and meditation can soothe muscle tightness, calm the mind, and promote relief from discomfort.
  • Gentle Exercise: Participate in low-impact activities, such as yoga or short walks, to improve flexibility, reduce muscle tension, and alleviate discomfort.
  • Consult a physician: If your symptoms don't improve or get worse, go to the doctor for help and guidance.
  • Exercising regularly helps lower the risk of heart problems.
  • Maintain a healthy diet, including vegetables and fruits.
  • Rest well; get enough sleep.
  • Manage stress with yoga and meditation.
  • Limit alcohol and smoking.
  • Get enough sleep. Maintain a regular sleep cycle.
  • Eat a healthy diet and exercise regularly.
  • Manage stress with yoga or meditation.
  • Limit alcohol and caffeine.
  • Avoid driving or operating machinery unless you are alert.

Directions for Use

  • Your doctor will determine the appropriate dosage and timing of Rufenyl 50 mcg Injection 2 ml based on your body weight.
  • Rufenyl 50 mcg Injection 2 ml is administered by a healthcare professional in a medical setting.
  • Do not self-administer it.
Rufenyl 50 mcg Injection 2 ml contains Fentanyl, which is primarily used to treat pain. It works by blocking a chemical messenger in the brain responsible for causing pain. Hence, changing the way the brain and nervous system respond to pain.
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Alcohol

Unsafe

Rufenyl 50 mcg Injection 2 ml with alcohol may cause dizziness or drowsiness. Besides this, it can also damage your liver if taken for a longer duration. So, avoid or limit intake of alcoholic beverages with Rufenyl 50 mcg Injection 2 ml.

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Pregnancy

Unsafe

Rufenyl 50 mcg Injection 2 ml is a pregnancy category C drug. Generally, it is not recommended for use in pregnancy as it may harm your foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving Rufenyl 50 mcg Injection 2 ml. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Unsafe

It may be unsafe to use during breastfeeding as it may cause sleepiness and decreased heart rate in your infant. It is not recommended for use in breastfeeding. Hence, if you are breastfeeding, inform your doctor before receiving Rufenyl 50 mcg Injection 2 ml. Your doctor may suggest you to stop feeding while on treatment with this medicine.

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Driving

Unsafe

Rufenyl 50 mcg Injection 2 ml causes dizziness, sleepiness, and drowsiness. So, do not drive or operate any machinery after taking this medicine until you are alert.

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before receiving Rufenyl 50 mcg Injection 2 ml. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor before receiving Rufenyl 50 mcg Injection 2 ml. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Caution

Rufenyl 50 mcg Injection 2 ml is not recommended for children below the age of 18 years.

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Heart

Consult your doctor

Please inform your doctor if you have a history of heart disease before using Rufenyl 50 mcg Injection 2 ml. Your doctor will prescribe it only if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Limited information available for use of Rufenyl 50 mcg Injection 2 ml in elderly patients. Please consult your doctor.

Since Rufenyl 50 mcg Injection 2 ml is administered by a healthcare professional, an overdose is unlikely to occur. However, seek medical attention if you experience muscle stiffness, a decrease in heart rate, low blood pressure, a fall in body temperature, and breathing difficulties that may cause your skin to turn blue.

Diet & Lifestyle Advise

  • Do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do stretching and low-impact aerobic exercises like walking on a treadmill, bike riding, and swimming. You can also strengthen your muscles by lifting light weights.
  • In the chronic condition of arthritis or joint pain, including fish like salmon, trout, tuna, and sardines. These fishes are enriched with omega-3 fatty acids that have a minimum level of chemicals called cytokines, which ramp up inflammation.
  • Your sitting posture is important, especially when you have pain and inflammation. Try to sit as little as possible, and only for a short duration of time. Long-term immobility is harmful in conditions like arthritis.  Use back support like a rolled-up towel to minimise pain at the back of your spine curve. Keep your knees and hips at a right angle. Besides this, you can also use a footrest if required.
  • Include a diet rich in whole grains, vegetables, and fruits. This is a healthier option than eating many simple carbohydrates in processed foods.

Have a query?

Drug Warnings

Do not receive Rufenyl 50 mcg Injection 2 ml if you are allergic to opioids or any ingredients of Rufenyl 50 mcg Injection 2 ml.Inform your doctor if you have respiratory disorders, heart diseases, high blood pressure, liver/kidney disease or hypothyroidism (underactive thyroid) before starting treatment with Rufenyl 50 mcg Injection 2 ml. Do not take Rufenyl 50 mcg Injection 2 ml for a prolonged time, Rufenyl 50 mcg Injection 2 ml contains fentanyl that may lead to mental or physical dependence on Rufenyl 50 mcg Injection 2 ml. Do not take Rufenyl 50 mcg Injection 2 ml if you are pregnant or breastfeeding, as it may cause adverse effects on the baby. Rufenyl 50 mcg Injection 2 ml is not recommended for children below 18 years of age. Using MAO inhibitor medicine along with Rufenyl 50 mcg Injection 2 ml may lead to serious side effects. Hence inform your doctor if you are using any such medicine. Rufenyl 50 mcg Injection 2 ml should be taken with extreme caution in patients who have a history of alcoholism or drug abuse. Avoid consuming alcohol while on this medication, as it can lead to excessive sleepiness. Blood pressure and cardiovascular (heart) status should be monitored closely during the treatment with Rufenyl 50 mcg Injection 2 ml, especially in people affected with high blood pressure and a history of heart failure.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Rufenyl 50 mcg Injection 2 ml:
Taking Linezolid with Rufenyl 50 mcg Injection 2 ml may increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although there is an interaction between Linezolid and Rufenyl 50 mcg Injection 2 ml, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, muscle pain, stomach cramps, vomiting, and diarrhoea. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Rufenyl 50 mcg Injection 2 ml:
Taking Safinamide with Rufenyl 50 mcg Injection 2 ml can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Safinamide with Rufenyl 50 mcg Injection 2 ml is not recommended as it can result in an interaction, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), increased heart rate, fever, excessive sweating, muscle pain, stomach cramps, vomiting, and loose stools. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Rufenyl 50 mcg Injection 2 ml:
Taking Rufenyl 50 mcg Injection 2 ml and mifepristone may significantly increase the blood levels of Rufenyl 50 mcg Injection 2 ml, which may increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between mifepristone and Rufenyl 50 mcg Injection 2 ml, they can be taken together if advised by a doctor. Do not stop using any medications without talking to your doctor.
FentanylSecobarbital
Severe
How does the drug interact with Rufenyl 50 mcg Injection 2 ml:
Coadministration of secobarbital and Rufenyl 50 mcg Injection 2 ml can increase the risk of side effects such as breathing problems.

How to manage the interaction:
Although taking Rufenyl 50 mcg Injection 2 ml together with secobarbital can result in an interaction, they can be taken together if prescribed by your doctor. However, consult a doctor if you experience watery eyes, runny nose, sneezing, excessive sweating, fever, chills, rapid heartbeat, body aches, abdominal cramping, vomiting, diarrhea, and weight loss. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Rufenyl 50 mcg Injection 2 ml:
Co-administration of Imatinib can raise the levels of Rufenyl 50 mcg Injection 2 ml in the blood and increase its effects.

How to manage the interaction:
Although taking Rufenyl 50 mcg Injection 2 ml together with Imatinib can result in an interaction, they can be taken together if prescribed by a doctor. However, consult your doctor if you feel sleepy or have difficulty breathing. Do not stop taking any medication without consulting a doctor.
How does the drug interact with Rufenyl 50 mcg Injection 2 ml:
Combining Atracurium with Rufenyl 50 mcg Injection 2 ml can increase the risk of irregular heart rhythm and low blood pressure.

How to manage the interaction:
There may be a possibility of interaction between Atracurium and Rufenyl 50 mcg Injection 2 ml, but it can be taken if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Rufenyl 50 mcg Injection 2 ml:
Coadministration of Rufenyl 50 mcg Injection 2 ml and phenytoin may reduce the blood levels of Rufenyl 50 mcg Injection 2 ml, which may make the medication less effective in treating your pain.

How to manage the interaction:
Although taking Rufenyl 50 mcg Injection 2 ml together with Phenytoin can result in an interaction, they can be taken together if prescribed by your doctor. However, consult a doctor if you experience watery eyes, a runny nose, sneezing, excessive sweating, fever, depression, tremors, rapid heartbeat, body aches, abdominal cramping, vomiting, or diarrhea. Do not stop taking any medication without consulting a doctor.
How does the drug interact with Rufenyl 50 mcg Injection 2 ml:
Coadministration of Dasatinib with Rufenyl 50 mcg Injection 2 ml may significantly increase the blood levels and effects of Rufenyl 50 mcg Injection 2 ml.

How to manage the interaction:
Although there is an interaction between Rufenyl 50 mcg Injection 2 ml and Dasatinib, they can be taken together if prescribed by a doctor. However, consult a doctor immediately if you experience excessive sleepiness, difficulty breathing, and/or shortness of breath. Do not discontinue using any medications without consulting a doctor.
How does the drug interact with Rufenyl 50 mcg Injection 2 ml:
Taking Rufenyl 50 mcg Injection 2 ml and Ketamine together can increase the risk of adverse effects.

How to manage the interaction:
Taking Ketamine with Rufenyl 50 mcg Injection 2 ml together can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms - sleepy, confused, or having trouble focusing- contact your doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Rufenyl 50 mcg Injection 2 ml:
Co-administration of Rufenyl 50 mcg Injection 2 ml with vortioxetine can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Although there is an interaction between vortioxetine and Rufenyl 50 mcg Injection 2 ml together can cause an interaction, they can be taken together if prescribed by a doctor. However, if you experience confusion, hallucinations (seeing and hearing things that do not exist), increased heart rate, fever, muscle pain or stiffness, stomach cramps, vomiting, or diarrhea, consult a doctor. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Yes
[NARCOTIC (OPIOID) ANALGESIC]

FAQs

Rufenyl 50 mcg Injection 2 ml is used to relieve pain.

Rufenyl 50 mcg Injection 2 ml contains Fentanyl which works by blocking a chemical messenger in the brain responsible for causing pain. Hence, changing the way the brain and nervous system respond to pain.

Yes, Rufenyl 50 mcg Injection 2 ml sometimes may make you breathe more slowly than usual or can cause shortness of breath. If you feel so, please inform your doctor immediately. Also, people with any breathing problems should inform their doctor before starting Rufenyl 50 mcg Injection 2 ml.

Elderly patients (aged more than 65 years) are more likely to have confusion and sleepiness or age-related health issues, which may require caution and an adjustment in the dose for patients receiving Rufenyl 50 mcg Injection 2 ml. So, it is better to consult a doctor before receiving this medicine.

Rufenyl 50 mcg Injection 2 ml is a habit-forming drug. It is not likely to be addictive if you take it for 2-4 weeks. However, if the doctor has prescribed you for more than 2-4 weeks, your doctor may reduce your dose before completely stopping it.

Do not stop receiving Rufenyl 50 mcg Injection 2 ml until instructed by your doctor. You may get side effects like confusion, depression, nervousness, sweating, and diarrhea. Your doctor may lower the dose of Rufenyl 50 mcg Injection 2 ml if using it for more than 2-4 weeks of treatment to reduce side effects.

Be careful while receiving Rufenyl 50 mcg Injection 2 ml as it may cause dizziness, light-headedness, and fainting when you get up too quickly from a lying position. This is more common when you first start receiving Rufenyl 50 mcg Injection 2 ml. To overcome this problem, get out of bed slowly, resting your feet on the floor for a few minutes before standing up. Avoid consumption of alcohol while treatment with Rufenyl 50 mcg Injection 2 ml as it may lead to dangerous side effects.

The side effects of Rufenyl 50 mcg Injection 2 ml include sleepiness, dizziness, increased or decreased blood pressure, and irregular heartbeat in some cases. Most of these side effects resolve on their own over time. However, consult the doctor if any of these side effects persist or worsen.

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